Histogram Matched Chest X-Rays Based Tuberculosis Detection Using CNN

Tuberculosis (TB) is a severe infection that mostly affects the lungs and kills millions of people’s lives every year. Tuberculosis can be diagnosed using chest X-rays (CXR) and data-driven deep learning (DL) approaches. Because of its better automated feature extraction capability, convolutional neural networks (CNNs) trained on natural images are particularly effective in image categorization. A combination of 3001 normal and 3001 TB CXR images was gathered for this study from different accessible public datasets. Ten different deep CNNs (Resnet50, Resnet101, Resnet152, InceptionV3, VGG16, VGG19, DenseNet121, DenseNet169, DenseNet201, MobileNet) are trained and tested for identifying TB and normal cases. This study presents a deep CNN approach based on histogram matched CXR images that does not require object segmentation of interest, and this coupled methodology of histogram matching with the CXRs improves the accuracy and detection performance of CNN models for TB detection. Furthermore, this research contains two separate experiments that used CXR images with and without histogram matching to classify TB and non-TB CXRs using deep CNNs. It was able to accurately detect TB from CXR images using pre-processing, data augmentation, and deep CNN models. Without histogram matching the best accuracy, sensitivity, specificity, precision and F1-score in the detection of TB using CXR images among ten models are 99.25%, 99.48%, 99.52%, 99.48% and 99.22% respectively. With histogram matching the best accuracy, sensitivity, specificity, precision and F1-score are 99.58%, 99.82%, 99.67%, 99.65% and 99.56% respectively. The proposed methodology, which has cutting-edge performance, will be useful in computer-assisted TB diagnosis and aids in minimizing irregularities in TB detection in developing countries.     

Detection of COVID-19 from chest X-ray images: Boosting the performance with convolutional neural network and transfer learning

Coronavirus disease (COVID-19) is a pandemic that has caused thousands of casualties and impacts all over the world. Most countries are facing a shortage of COVID-19 test kits in hospitals due to the daily increase in the number of cases. Early detection of COVID-19 can protect people from severe infection. Unfortunately, COVID-19 can be misdiagnosed as pneumonia or other illness and can lead to patient death. Therefore, in order to avoid the spread of COVID-19 among the population, it is necessary to implement an automated early diagnostic system as a rapid alternative diagnostic system. Several researchers have done very well in detecting COVID-19; however, most of them have lower accuracy and overfitting issues that make early screening of COVID-19 difficult. Transfer learning is the most successful technique to solve this problem with higher accuracy. In this paper, we studied the feasibility of applying transfer learning and added our own classifier to automatically classify COVID-19 because transfer learning is very suitable for medical imaging due to the limited availability of data. In this work, we proposed a CNN model based on deep transfer learning technique using six different pre-trained architectures, including VGG16, DenseNet201, MobileNetV2, ResNet50, Xception, and EfficientNetB0. A total of 3886 chest X-rays (1200 cases of COVID-19, 1341 healthy and 1345 cases of viral pneumonia) were used to study the effectiveness of the proposed CNN model. A comparative analysis of the proposed CNN models using three classes of chest X-ray datasets was carried out in order to find the most suitable model. Experimental results show that the proposed CNN model based on VGG16 was able to accurately diagnose COVID-19 patients with 97.84% accuracy, 97.90% precision, 97.89% sensitivity, and 97.89% of F1-score. Evaluation of the test data shows that the proposed model produces the highest accuracy among CNNs and seems to be the most suitable choice for COVID-19 classification. We believe that in this pandemic situation, this model will support healthcare professionals in improving patient screening.     

Deep-CoV: An integrated deep learning model to detect COVID-19 using chest X-ray and CT images

The COVID-19 virus has fatal effect on lung function and due to its rapidity the early detection is necessary at the moment. The radiographic images have already been used by the researchers for the early diagnosis of COVID-19. Though several existing research exhibited very good performance with either x-ray or computer tomography (CT) images, to the best of our knowledge no such work has reported the assembled performance of both x-ray and CT images. Thus increase in accuracy with higher scalability is the main concern of the recent research. In this article, an integrated deep learning model has been developed for detection of COVID-19 at an early stage using both chest x-ray and CT images. The lack of publicly available data about COVID-19 disease motivates the authors to combine three benchmark datasets into a single dataset of large size. The proposed model has applied various transfer learning techniques for feature extraction and to find out the best suite. Finally the capsule network is used to categorize the sub-dataset into COVID positive and normal patients. The experimental results show that, the best performance exhibits by the ResNet50 with capsule network as an extractor-classifier pair with the combined dataset, which is composed of 575 numbers of x-ray images and 930 numbers of CT images. The proposed model achieves accuracy of 98.2% and 97.8% with x-ray and CT images, respectively, and an average of 98%.     

Corona-Nidaan: lightweight deep convolutional neural network for chest X-Ray based COVID-19 infection detection

The coronavirus COVID-19 pandemic is today’s major public health crisis, we have faced since the Second World War. The pandemic is spreading around the globe like a wave, and according to the World Health Organization’s recent report, the number of confirmed cases and deaths are rising rapidly. COVID-19 pandemic has created severe social, economic, and political crises, which in turn will leave long-lasting scars. One of the countermeasures against controlling coronavirus outbreak is specific, accurate, reliable, and rapid detection technique to identify infected patients. The availability and affordability of RT-PCR kits remains a major bottleneck in many countries, while handling COVID-19 outbreak effectively. Recent findings indicate that chest radiography anomalies can characterize patients with COVID-19 infection. In this study, Corona-Nidaan, a lightweight deep convolutional neural network (DCNN), is proposed to detect COVID-19, Pneumonia, and Normal cases from chest X-ray image analysis; without any human intervention. We introduce a simple minority class oversampling method for dealing with imbalanced dataset problem. The impact of transfer learning with pre-trained CNNs on chest X-ray based COVID-19 infection detection is also investigated. Experimental analysis shows that Corona-Nidaan model outperforms prior works and other pre-trained CNN based models. The model achieved 95% accuracy for three-class classification with 94% precision and recall for COVID-19 cases. While studying the performance of various pre-trained models, it is also found that VGG19 outperforms other pre-trained CNN models by achieving 93% accuracy with 87% recall and 93% precision for COVID-19 infection detection. The model is evaluated by screening the COVID-19 infected Indian Patient chest X-ray dataset with good accuracy.

     

Deep learning based detection of COVID-19 from chest X-ray images

The whole world is facing a health crisis, that is unique in its kind, due to the COVID-19 pandemic. As the coronavirus continues spreading, researchers are concerned by providing or help provide solutions to save lives and to stop the pandemic outbreak. Among others, artificial intelligence (AI) has been adapted to address the challenges caused by pandemic. In this article, we design a deep learning system to extract features and detect COVID-19 from chest X-ray images. Three powerful networks, namely ResNet50, InceptionV3, and VGG16, have been fine-tuned on an enhanced dataset, which was constructed by collecting COVID-19 and normal chest X-ray images from different public databases. We applied data augmentation techniques to artificially generate a large number of chest X-ray images: Random Rotation with an angle between ??10 and 10 degrees, random noise, and horizontal flips. Experimental results are encouraging: the proposed models reached an accuracy of 97.20?% for Resnet50, 98.10?% for InceptionV3, and 98.30?% for VGG16 in classifying chest X-ray images as Normal or COVID-19. The results show that transfer learning is proven to be effective, showing strong performance and easy-to-deploy COVID-19 detection methods. This enables automatizing the process of analyzing X-ray images with high accuracy and it can also be used in cases where the materials and RT-PCR tests are limited.

     

COVID-19 chest X-ray image classification in the presence of noisy labels

The Corona Virus Disease 2019 (COVID-19) has been declared a worldwide pandemic, and a key method for diagnosing COVID-19 is chest X-ray imaging. The application of convolutional neural network with medical imaging helps to diagnose the disease accurately, where the label quality plays an important role in the classification problem of COVID-19 chest X-rays. However, most of the existing classification methods ignore the problem that the labels are hardly completely true and effective, and noisy labels lead to a significant degradation in the performance of image classification frameworks. In addition, due to the wide distribution of lesions and the large number of local features of COVID-19 chest X-ray images, existing label recovery algorithms have to face the bottleneck problem of the difficult reuse of noisy samples. Therefore, this paper introduces a general classification framework for COVID-19 chest X-ray images with noisy labels and proposes a noisy label recovery algorithm based on subset label iterative propagation and replacement (SLIPR). Specifically, the proposed algorithm first obtains random subsets of the samples multiple times. Then, it integrates several techniques such as principal component analysis, low-rank representation, neighborhood graph regularization, and k-nearest neighbor for feature extraction and image classification. Finally, multi-level weight distribution and replacement are performed on the labels to cleanse the noise. In addition, for the label-recovered dataset, high confidence samples are further selected as the training set to improve the stability and accuracy of the classification framework without affecting its inherent performance. In this paper, three typical datasets are chosen to conduct extensive experiments and comparisons of existing algorithms under different metrics. Experimental results on three publicly available COVID-19 chest X-ray image datasets show that the proposed algorithm can effectively recover noisy labels and improve the accuracy of the image classification framework by 18.9% on the Tawsifur dataset, 19.92% on the Skytells dataset, and 16.72% on the CXRs dataset. Compared to the state-of-the-art algorithms, the gain of classification accuracy of SLIPR on the three datasets can reach 8.67%-19.38%, and the proposed algorithm also has certain scalability while ensuring data integrity.     

Prediction of Covid-19 Based on Chest X-Ray Images Using Deep Learning with CNN

The COVID-19 pandemic has caused trouble in people’s daily lives and ruined several economies around the world, killing millions of people thus far. It is essential to screen the affected patients in a timely and cost-effective manner in order to fight this disease. This paper presents the prediction of COVID-19 with Chest X-Ray images, and the implementation of an image processing system operated using deep learning and neural networks. In this paper, a Deep Learning, Machine Learning, and Convolutional Neural Network-based approach for predicting Covid-19 positive and normal patients using Chest X-Ray pictures is proposed. In this study, machine learning tools such as TensorFlow were used for building and training neural nets. Scikit-learn was used for machine learning from end to end. Various deep learning features are used, such as Conv2D, Dense Net, Dropout, Maxpooling2D for creating the model. The proposed approach had a classification accuracy of 96.43 percent and a validation accuracy of 98.33 percent after training and testing the X-Ray pictures. Finally, a web application has been developed for general users, which will detect chest x-ray images either as covid or normal. A GUI application for the Covid prediction framework was run. A chest X-ray image can be browsed and fed into the program by medical personnel or the general public.     

An automated CNN architecture search for glaucoma diagnosis based on NEAT

Glaucoma is an ocular disease that causes damage to the optic nerve, inducing successive narrowing of the visual field in affected patients due to an increased intraocular pressure, which can lead patients to blindness in an advanced stage without clinical reversal. For several years, the use of deep learning with convolutional neural networks (CNNs) has been successfully put into practice for several years. However, building a deep learning network requires an amount of experiments to find the fittest parameters, best choice of layers and an amount of available data. Thus it is not always able to produce satisfactory results due to the amount of parameters that need to be configured to adapt the CNN architecture to the problem in question, in most cases, with small datasets. Based on this scenario, this paper proposes and analyzes a CNN architecture construction from scratch, based on Neuroevolution of Augmenting Topologies for diagnosing glaucoma from fundus images. The method was evaluated with RIM-ONE and the combination of five glaucoma datasets in which we highlight 0.961 and 0.943 of f1-score, respectively for each dataset.

     

Leveraging Multimodal Ensemble Fusion-Based Deep Learning for COVID-19 on Chest Radiographs

Recently, COVID-19 has posed a challenging threat to researchers, scientists, healthcare professionals, and administrations over the globe, from its diagnosis to its treatment. The researchers are making persistent efforts to derive probable solutions for managing the pandemic in their areas. One of the widespread and effective ways to detect COVID-19 is to utilize radiological images comprising X-rays and computed tomography (CT) scans. At the same time, the recent advances in machine learning (ML) and deep learning (DL) models show promising results in medical imaging. Particularly, the convolutional neural network (CNN) model can be applied to identifying abnormalities on chest radiographs. While the epidemic of COVID-19, much research is led on processing the data compared with DL techniques, particularly CNN. This study develops an improved fruit fly optimization with a deep learning-enabled fusion (IFFO-DLEF) model for COVID-19 detection and classification. The major intention of the IFFO-DLEF model is to investigate the presence or absence of COVID-19. To do so, the presented IFFO-DLEF model applies image pre-processing at the initial stage. In addition, the ensemble of three DL models such as DenseNet169, EfficientNet, and ResNet50, are used for feature extraction. Moreover, the IFFO algorithm with a multilayer perceptron (MLP) classification model is utilized to identify and classify COVID-19. The parameter optimization of the MLP approach utilizing the IFFO technique helps in accomplishing enhanced classification performance. The experimental result analysis of the IFFO-DLEF model carried out on the CXR image database portrayed the better performance of the presented IFFO-DLEF model over recent approaches.     

Stacked-autoencoder-based model for COVID-19 diagnosis on CT images

With the outbreak of COVID-19, medical imaging such as computed tomography (CT) based diagnosis is proved to be an effective way to fight against the rapid spread of the virus. Therefore, it is important to study computerized models for infectious detection based on CT imaging. New deep learning-based approaches are developed for CT assisted diagnosis of COVID-19. However, most of the current studies are based on a small size dataset of COVID-19 CT images as there are less publicly available datasets for patient privacy reasons. As a result, the performance of deep learning-based detection models needs to be improved based on a small size dataset. In this paper, a stacked autoencoder detector model is proposed to greatly improve the performance of the detection models such as precision rate and recall rate. Firstly, four autoencoders are constructed as the first four layers of the whole stacked autoencoder detector model being developed to extract better features of CT images. Secondly, the four autoencoders are cascaded together and connected to the dense layer and the softmax classifier to constitute the model. Finally, a new classification loss function is constructed by superimposing reconstruction loss to enhance the detection accuracy of the model. The experiment results show that our model is performed well on a small size COVID-2019 CT image dataset. Our model achieves the average accuracy, precision, recall, and F1-score rate of 94.7%, 96.54%, 94.1%, and 94.8%, respectively. The results reflect the ability of our model in discriminating COVID-19 images which might help radiologists in the diagnosis of suspected COVID-19 patients.

     

A novel transfer learning approach for the classification of histological images of colorectal cancer

Colorectal cancer (CRC) is the second most diagnosed cancer in the United States. It is identified by histopathological evaluations of microscopic images of the cancerous region, relying on a subjective interpretation. The Colorectal Histology dataset used in this study contains 5000 images, made available by the University Medical Center Mannheim. This approach proposes the automatic identification of eight types of tissues found in CRC histopathological evaluation. We apply Transfer Learning from architectures of Convolutional Neural Networks (CNNs). We modify the structures of CNNs to extract features from the images and input them to well-known machine learning methods: Naive Bayes, Multilayer Perceptron, k-Nearest Neighbors, Random Forest, and Support Vector Machine (SVM). We evaluated 108 extractor–classifier combinations. The one that achieved the best results is DenseNet169 with SVM (RBF), reaching an Accuracy of 92.083% and F1-Score of 92.117%. Therefore, our approach is capable of distinguishing tissues found in CRC histopathological evaluation.

     

FaNet: fast assessment network for the novel coronavirus (COVID-19) pneumonia based on 3D CT imaging and clinical symptoms

The novel coronavirus (COVID-19) pneumonia has become a serious health challenge in countries worldwide. Many radiological findings have shown that X-ray and CT imaging scans are an effective solution to assess disease severity during the early stage of COVID-19. Many artificial intelligence (AI)-assisted diagnosis works have rapidly been proposed to focus on solving this classification problem and determine whether a patient is infected with COVID-19. Most of these works have designed networks and applied a single CT image to perform classification; however, this approach ignores prior information such as the patient’s clinical symptoms. Second, making a more specific diagnosis of clinical severity, such as slight or severe, is worthy of attention and is conducive to determining better follow-up treatments. In this paper, we propose a deep learning (DL) based dual-tasks network, named FaNet, that can perform rapid both diagnosis and severity assessments for COVID-19 based on the combination of 3D CT imaging and clinical symptoms. Generally, 3D CT image sequences provide more spatial information than do single CT images. In addition, the clinical symptoms can be considered as prior information to improve the assessment accuracy; these symptoms are typically quickly and easily accessible to radiologists. Therefore, we designed a network that considers both CT image information and existing clinical symptom information and conducted experiments on 416 patient data, including 207 normal chest CT cases and 209 COVID-19 confirmed ones. The experimental results demonstrate the effectiveness of the additional symptom prior information as well as the network architecture designing. The proposed FaNet achieved an accuracy of 98.28% on diagnosis assessment and 94.83% on severity assessment for test datasets. In the future, we will collect more covid-CT patient data and seek further improvement.

     

基于三种高分辨率影像样本迁移学习的城市水体提取研究

水体提取是遥感监测城市水环境必不可少的步骤,提取城市中的细小水体目前已成为遥感影像深度学习领域的热点。但是,深度学习需要大量的样本数据集作为输入,而且不同空间分辨率影像往往需要构建不同的样本集。如果影像的空间分辨率差异不大,可以先采用分辨率较低的影像样本训练模型,并加入少量的较高分辨率样本再次训练模型,这种模型可以保证精度和节约时间。研究选用了U-net图像分割模型,针对3种不同空间分辨率——分别为0.5 m、0.8 m和2 m的影像进行样本迁移学习。发现2 m到0.8 m、2 m到0.5 m、0.8 m到0.5 m 3种迁移学习后,提取水体结果对应评价指标F1-score、MIoU、Kappa都在0.80以上。在分辨率差异不大的前提下,这种从较低分辨率样本迁移到较高分辨率影像提取城市水体的方法基本可行,结果精度较好,适用于缺水型城市的水体提取。     

A central-point-enhanced convolutional neural network for high-resolution remote-sensing image classification

As one of the most important algorithms in the field of deep learning technology, the convolutional neural network (CNN) has been successfully applied in many fields. CNNs can recognize objects in an image by considering morphology and structure rather than simply individual pixels. One advantage of CNNs is that they exhibit translational invariance; when an image contains a certain degree of distortion or shift, a CNN can still recognize the object in the image. However, this advantage becomes a disadvantage when CNNs are applied to pixel-based classification of remote-sensing images, because their translational invariance characteristics causes distortions in land-cover boundaries and outlines in the classification result image. This problem severely limits the application of CNNs in remote-sensing classification. To solve this problem, we propose a central-point-enhanced convolutional neural network (CE-CNN) to classify high-resolution remote-sensing images. By introducing the central-point-enhanced layer when classifying a sample, the CE-CNN increases the weight of the central point in feather maps while preserving the original textures and characteristics. In our experiment, we selected four representative positions on a high-resolution remote-sensing image to test the classification ability of the proposed method and compared the CE-CNN with the traditional multi-layer perceptron (MLP) and a traditional CNN. The results show that the proposed method can not only achieves a higher classification accuracy but also less distortion and fewer incorrect results at the boundaries of land covers. We further compared the CE-CNN with six state-of-the-art methods: k-NN, maximum likelihood, classification and regression tree (CART), MLP, support vector machine, and CNN. The results show that the CE-CNN’s classification accuracy is better than the other methods.     

Smart COVID-3D-SCNN: A Novel Method to Classify X-ray Images of COVID-19

The outbreak of the novel coronavirus has spread worldwide, and millions of people are being infected. Image or detection classification is one of the first application areas of deep learning, which has a significant contribution to medical image analysis. In classification detection, one or more images (detection) are usually used as input, and diagnostic variables (such as whether there is a disease) are used as output. The novel coronavirus has spread across the world, infecting millions of people. Early-stage detection of critical cases of COVID-19 is essential. X-ray scans are used in clinical studies to diagnose COVID-19 and Pneumonia early. For extracting the discriminative features through these modalities, deep convolutional neural networks (CNNs) are used. A siamese convolutional neural network model (COVID-3D-SCNN) is proposed in this study for the automated detection of COVID-19 by utilizing X-ray scans. To extract the useful features, we used three consecutive models working in parallel in the proposed approach. We acquired 575 COVID-19, 1200 non-COVID, and 1400 pneumonia images, which are publicly available. In our framework, augmentation is used to enlarge the dataset. The findings suggest that the proposed method outperforms the results of comparative studies in terms of accuracy 96.70%, specificity 95.55%, and sensitivity 96.62% over (COVID-19 vs. non-COVID19 vs. Pneumonia).     

COVID-19医学影像数据集及研究进展

由于影像学技术在新型冠状病毒肺炎（COVID-19）的诊断和评估中发挥了重要作用,COVID-19相关数据集陆续被公布,但目前针对相关文献中数据集以及研究进展的整理相对较少。为此,通过COVID-19相关的期刊论文、报告和相关开源数据集网站,对涉及到的新冠肺炎数据集及深度学习模型进行整理和分析,包括计算机断层扫描（CT）图像数据集和X射线（CXR）图像数据集。对这些数据集呈现的医学影像的特征进行分析;重点论述开源数据集,以及在相关数据集上表现较好的分类和分割模型。最后讨论了肺部影像学技术未来的发展趋势。     

基于深度学习的COVID-19智能诊断系统

本研究旨在探索运用深度学习的方法辅助医生利用胸部X光片进行COVID-19诊断的可行性和准确性。首先利用公开的COVID-QU-Ex Dataset训练集训练一个UNet分割模型,实现肺部ROI区域的自动分割。其次完成对该公共数据集肺部区域的自动提取预处理。再次利用预处理后的三分类影像数据（新冠肺炎、其它肺炎、正常）采用迁移学习的方式训练了一个分类模型MBCA-COVIDNET,该模型以MobileNetV2作为骨干网络,并在其中加入坐标注意力机制（CA）。最后利用训练好的模型和Hugging Face开源软件搭建了一套方便医生使用的COVID-19智能辅助诊断系统。该模型在COVID-QU-Ex Dataset测试集上取得了高达97.98%的准确率,而该模型的参数量和MACs仅有2.23M和0.33G,易于在硬件设备上进行部署。该智能诊断系统能够很好的辅助医生进行基于胸片的COVID-19诊断,提升诊断的准确率以及诊断效率。