共查询到20条相似文献,搜索用时 31 毫秒
1.
The objective of this study was to investigate if health data recorded by Canadian dairy producers can be used for genetic selection. Eight diseases are recorded by producers on a voluntary basis: mastitis, displaced abomasum, ketosis, milk fever, retained placenta, metritis, cystic ovaries, and lameness. Between 40 to 60% of all herds had to be excluded by editing procedures for each trait, assuming unreliable health recording. All analyses were carried out for first-lactation Holstein cows. The majority of disease cases occurred in the first month of lactation. Mean disease frequencies were 12.6, 3.7, 4.5, 4.6, 10.8, 8.2, and 9.2% for mastitis, displaced abomasum, ketosis, retained placenta, metritis, cystic ovaries, and lameness, respectively. Milk fever was very rare in first-lactation cows with a frequency of only 0.20%, and was, therefore, not considered in the analyses. Univariate and bivariate linear animal models were fitted. Heritabilities for mastitis, displaced abomasum, ketosis, retained placenta, metritis, cystic ovaries, and lameness were 0.02, 0.06, 0.03, 0.03, 0.02, 0.03, and 0.01, respectively. Genetic correlations between diseases were mostly positive. The strongest genetic correlations were found between displaced abomasum and ketosis (0.64) and between retained placenta and metritis (0.62). The remaining genetic correlations ranged from -0.22 (between metritis and lameness) to 0.49 (between mastitis and lameness). In agreement with the genetic correlations, the largest phenotypic correlations were found between displaced abomasum and ketosis (0.27) and retained placenta and metritis (0.14). All other phenotypic correlations were low and close to zero (0.00 to 0.06). Pearson correlations between breeding values for health traits and other routinely evaluated traits were computed, which revealed noticeable favorable relationships to direct herd life and fertility. In addition, a moderate favorable association was found between mastitis and somatic cell score. Mastitis is the most promising trait to be included in routine genetic evaluation, because it is the most recorded disease and has a high frequency and positive genetic correlations to all other health traits. Although, about 40% of all Canadian dairy producers participate in the health-recording system, a large proportion of the data are lost after data validation. Thus, dairy producers should be encouraged to keep accurate and complete health data. 相似文献
2.
N. Vukasinovic N. Bacciu C.A. Przybyla P. Boddhireddy S.K. DeNise 《Journal of dairy science》2017,100(1):428-438
In March 2016, Zoetis Genetics offered the first commercially available evaluation for wellness traits of Holstein dairy cattle. Phenotypic data on health events, pedigree, and genotypes were collected directly from producers upon obtaining their permission. Among all recorded health events, 6 traits were chosen to be included in the evaluation: mastitis, metritis, retained placenta, displaced abomasum, ketosis, and lameness. Each trait was defined as a binary event, having a value of 1 if a cow has been recorded with a disorder at any point during the lactation and zero otherwise. The number of phenotypic records ranged from 1.8 million for ketosis to 4.1 million for mastitis. Over 14 million pedigree records and 114,216 genotypes were included in the evaluation. All traits were analyzed using univariate threshold animal model with repeated observations, including fixed effect of parity and random effects of herd by year by season of calving, animal, and permanent environment. A total of 45,425 single nucleotide polymorphisms were used in the genomic analyses. Animals genotyped with low-density chips were imputed to the required number of single nucleotide polymorphisms. All analyses were based on the single-step genomic BLUP, a method that combines phenotype, pedigree, and genotype information. Predicted transmitting abilities were expressed in percentage points as a difference from the average estimated probability of a disorder in the base population. Reliabilities of breeding values were obtained by approximation based on partitioning of a function of reliability into contributions from records, pedigree, and genotypes. Reliabilities of genomic predicted transmitting abilities for young genotyped and pedigreed females without recorded health events had average values between 50.2% (displaced abomasum) and 51.9% (mastitis). Genomic predictions for wellness traits can provide new information about an animal’s genetic potential for health and new selection tools for dairy wellness improvement. 相似文献
3.
Emphasizing increased profit through increased dairy cow production has revealed a negative relationship of production with fitness and health traits. Decreased cow health can affect herd profitability through increased rates of involuntary culling and decreased or lost milk sales. The development of genomic selection methodologies, with accompanying substantial gains in reliability for low-heritability traits, may dramatically improve the feasibility of genetic improvement of dairy cow health. Producer-recorded health information may provide a wealth of information for improvement of dairy cow health, thus improving profitability. The principal objective of this study was to use health data collected from on-farm computer systems in the United States to estimate variance components and heritability for health traits commonly experienced by dairy cows. A single-step analysis was conducted to estimate genomic variance components and heritabilities for health events, including cystic ovaries, displaced abomasum, ketosis, lameness, mastitis, metritis, and retained placenta. A blended H matrix was constructed for a threshold model with fixed effects of parity and year-season and random effects of herd-year and sire. The single-step genomic analysis produced heritability estimates that ranged from 0.02 (standard deviation = 0.005) for lameness to 0.36 (standard deviation = 0.08) for retained placenta. Significant genetic correlations were found between lameness and cystic ovaries, displaced abomasum and ketosis, displaced abomasum and metritis, and retained placenta and metritis. Sire reliabilities increased, on average, approximately 30% with the incorporation of genomic data. From the results of these analyses, it was concluded that genetic selection for health traits using producer-recorded data are feasible in the United States, and that the inclusion of genomic data substantially improves reliabilities for these traits. 相似文献
4.
Path analysis and multiple logistic-normal regression were used to model the interrelationships between stated herd management practices and herd 30-d postpartum incidence rates of dystocia, retained placenta, and clinical postpartum metritis, cystic ovary, milk fever, ketosis, left displaced abomasum, and mastitis. Management risk factors were obtained from a personal interview questionnaire. Data were from 2141 multiparous Holstein calvings from May 1981 through April 1982 in 32 commercial herds in the vicinity of Cornell University. Farms where the stated policy was to administer low calcium diets to the dry cows experienced more dystocia and retained placenta. More dystocia was experienced on farms where the stated policy was to administer extra vitamin D to dry cows, where dry cows were housed with the milking cows, or where calving occurred in maternity pens rather than stanchions. There was an increased likelihood of milk fever and left displaced abomasum on farms on which the stated policy was to lead feed. Farms where dairy farmers treated cases of retained placenta had more retained placenta than farms on which the treatment was done by the veterinarian. Farms reporting the practice of feeding the cows to increase their weight during the dry period had increased odds of ketosis. 相似文献
5.
《Journal of dairy science》2022,105(1):495-508
Among other regulations, organic cows in the United States cannot receive antibiotics and preserve their organic status, emphasizing the importance of prevention of illness and benefit of high genetic merit for disease resistance. At the same time, data underlying national genetic evaluations primarily come from conventional cows, drawing concern to the possibility of a genotype by environment interaction whereby the value of a genotype varies depending on the environment, and potentially limits the relevance of these evaluations to organic cows. The objectives of this study were to characterize the genetics of and determine the presence of genotype by environment interaction for health traits in US organic dairy cows. Individual cow health data were obtained from 16 US Department of Agriculture certified organic dairy farms from across the United States that used artificial insemination and maintained detailed records. Data were obtained for the following traits: died, lameness, mastitis, metabolic diseases (displaced abomasum, ketosis, and milk fever), reproductive diseases (abortion, metritis, and retained placenta), transition health events (any health event occurring 21 d before or after parturition), and all health events. Binary phenotypes (1 = diseased, 0 = otherwise) for 38,949 lactations on 19,139 Holstein cows were used. Genotypes from 2,347 cows with 87.5% or greater Holstein breed-based representation were incorporated into single-step multitrait threshold animal models that included stayability (1 = completed lactation, 0 = otherwise). Gibbs sampling was used. Genomic predicted transmitting abilities (gPTA) from national genetic evaluations were obtained for sires for production, fitness, health, and conformation traits. We approximated genetic correlations for sires using these gPTA and our estimated breeding values. We also regressed health phenotypes on cow estimated breeding values and sire gPTA. Heritabilities (± standard error) ranged from 0.03 ± 0.01 (reproductive diseases) to 0.11 ± 0.03 (metabolic diseases). Most genetic correlations among health traits were positive, though the genetic correlation between metabolic disease and mastitis was ?0.42 ± 0.17. Approximate genetic correlations between disease resistance for our health trait categories and disease resistance for the nationally-evaluated health traits generally carried the expected sign with the strongest correlation for mastitis (0.72 ± 0.084). Regression coefficients carried the expected sign and were mostly different from zero, indicating that evaluations from primarily conventional herd data predicted health on organic farms. In conclusion, use of national evaluations for health traits should afford genetic improvement for health in US organic herds. 相似文献
6.
The objectives of this study were to calculate genetic correlations between health traits that were recorded in on-farm herd management software programs and to assess relationships between these traits and other traits that are routinely evaluated in US dairy sires. Data consisted of 272,576 lactation incidence records for displaced abomasum (DA), ketosis (KET), mastitis (MAST), lameness (LAME), cystic ovaries (CYST), and metritis (MET) from 161,622 cows in 646 herds. These data were collected between January 1, 2001 and December 31, 2003 in herds using the Dairy Comp 305, DHI-Plus, or PCDART herd management software programs. Binary incidence data for all disorders were analyzed simultaneously using a multiple-trait threshold sire model that included random sire and herd-year-season of calving effects. Although data from multiple lactations were available for some animals, our genetic analysis included only first parity records due to concerns about selection bias and improper modeling of the covariance structure. Heritability estimates for the presence or absence of each disorder during first lactation were 0.14 for DA, 0.06 for KET, 0.09 for MAST, 0.03 for LAME, 0.04 for CYST, and 0.06 for MET. Estimated genetic correlations were 0.45 between DA and KET, 0.42 between KET and CYST, 0.20 between MAST and LAME, 0.19 between KET and LAME, 0.17 between DA and CYST, 0.17 between KET and LAME, 0.17 between KET and MET, and 0.16 between LAME and CYST. All other correlations were negligible. Correlations between predicted transmitting abilities for the aforementioned health traits and existing production, type, and fitness traits were low, though it must be noted that these estimates may have been biased by low reliability of the health trait evaluations. Based on results of this study, it appears that genetic selection for health disorders recorded in on-farm software programs can be effective. These traits can be incorporated into selection indices directly, or they can be combined into composite traits, such as "reproductive disorders", "metabolic disorders", or "early lactation disorders". 相似文献
7.
Path analysis of dry period nutrition, postpartum metabolic and reproductive disorders, and mastitis in Holstein cows 总被引:6,自引:0,他引:6
C R Curtis H N Erb C J Sniffen R D Smith D S Kronfeld 《Journal of dairy science》1985,68(9):2347-2360
Path analysis and logistic regression were used to model direct and indirect relationships among clinical periparturient (within 30 d after calving) retained placenta, metritis, veterinary-assisted dystocia, uncomplicated and complicated ketosis, left displaced abomasum, parturient paresis, mastitis, and estimated nutrient intakes (protein, calcium, phosphorus, energy; coded into terciles) in the last 3 wk of the dry period. Data were from 1,374 multiparous Holstein lactations for calvings from March 1981 through February 1982 in 31 commercial herds in central New York. Periparturient disorders occurred as a complex. Odds ratios for the multiplicative effects of parturient paresis on incidence of veterinary-assisted dystocia, retained placenta, complicated ketosis, and clinical mastitis were 7.2, 4.0, 23.6, and 5.4, respectively. Reproductive disorders were interrelated. Retained placenta, left displaced abomasum, and parturient paresis directly increased risk of complicated ketosis (odds ratios were 16.4, 53.5, and 23.6, respectively). Higher terciles of estimated energy intake in the last 3 wk of the dry period decreased risk of veterinary-assisted dystocia and left displaced abomasum, while higher terciles of estimated protein intake decreased risk of retained placenta and uncomplicated ketosis. Estimated nutrient intakes were directly related to subsequent metabolic disorders and directly and indirectly related (mediated by metabolic disorders) to reproductive disorders. The study suggests that feeding higher intakes (relative to National Research Council recommendations) of protein and energy in the last 3 week of the dry period may reduce the incidence of metabolic and reproductive disorders. Exact recommendations as to the amounts and types of feed cannot be made from our results. 相似文献
8.
The relationship between milk yield and the incidence of some diseases in dairy cows 总被引:4,自引:0,他引:4
Fleischer P Metzner M Beyerbach M Hoedemaker M Klee W 《Journal of dairy science》2001,84(9):2025-2035
Logistic regression models were used to examine the relationship between milk yield and incidence of certain disorders. Lactations (n = 2197) of 1074 Holstein-Friesian cows from 10 dairies (25 to 146 cows per dairy) in Lower Saxony were studied. The 305-d yield from the previous and current lactations served as the standards for milk yield. Eight disorder complexes were considered: retained placenta, metritis, ovarian cysts, mastitis, claw diseases, milk fever, ketosis, and displaced abomasum. Each disorder complex was modeled separately. In addition to milk yield, the influences of the lactation number, the calving season and the other disorder complexes were examined with the "herd" factor taken into account. A correlation between retained placenta, mastitis, and milk fever to milk yield during the previous lactation was found to be probable and for ketosis and displaced abomasum such a correlation was found to be possible. A connection to the yield in the current lactation was shown for ovarian cysts, claw diseases, and milk fever. No relationship to milk yield existed for metritis. An influence of the lactation number was also demonstrated in various models. Single models allowed a demonstration of the influences of both milk yield and lactation number. Limitations of the model types are discussed. 相似文献
9.
LeBlanc SJ Duffield TF Leslie KE Bateman KG TenHag J Walton JS Johnson WH 《Journal of dairy science》2002,85(6):1416-1426
The objective of this study was to investigate parenteral vitamin E for the prevention of peripartum disease in dairy cows. A randomized clinical trial was conducted in 21 commercial dairy herds. Cows (n = 1142) were randomly assigned to receive either a single subcutaneous injection of 3000 IU of vitamin E, or placebo, 1 wk before expected calving. Serum alpha-tocopherol was significantly increased in treated cows at 7 and 14 d, but not at 21 d after injection. Overall, there were no significant differences between treatment groups in the incidence of retained placenta, clinical mastitis, metritis, endometritis, ketosis, displaced abomasum, or lameness. However, there was a conditional benefit of treatment for reduction of the incidence of retained placenta. Cows with marginal pretreatment vitamin E status (serum alpha-tocopherol to cholesterol mass ratio < 2.5 x 10(-3)) that received an injection of vitamin E tended to have reduced risk of retained placenta. However, in cows with adequate serum vitamin E, there was no reduction in the incidence of any disease. For clinical application, primiparous animals were most likely to benefit from prepartum injection of vitamin E. 相似文献
10.
Effects of diseases on test day milk yield and body weight of dairy cows from Danish research herds.
The pre- and postdisease interrelationships of energy corrected test day milk yield and body weight of dairy cows caused by mastitis, three reproductive disorders (retained placenta, metritis, cystic ovaries), and seven metabolic disorders (milk fever, ketosis, decreased rumen motility, enteritis, left displaced abomasum, right displaced abomasum, and off feed) were quantified by using mixed models analysis with repeated measures of continuous data. The data were weekly recordings from 4414 lactations collected in three Danish research herds. High milk yield was a risk factor for ketosis and enteritis. Heavier primiparous cows were more likely to contract mastitis. Milk yield was decreased for a disease-specific period for all study diseases except cystic ovaries and right displaced abomasum. Metabolic disorders had a detrimental effect on body weight. The highest weight loss (69 kg) was associated with left displaced abomasum. The persistence of the weight loss differed considerably among study diseases. Almost all weight loss occurred up to and including the initial week after diagnosis, which emphasized the detrimental effect of the subclinical stage. However, weekly measured body weight seemed superior to weekly energy corrected test day milk yield for disease detection only for decreased rumen motility and left displaced abomasum. This study demonstrates the importance of the predisease level for accurate estimation of the loss of milk yield and body weight from disease. 相似文献
11.
Periparturient traits in seven high dairy herds. Incidence rates, association with parity, and interrelationships among traits 总被引:5,自引:0,他引:5
O Markusfeld 《Journal of dairy science》1987,70(1):158-166
Interrelationships among nine periparturient traits and their association with parity were investigated in 8521 calvings of dairy cows examined routinely between 5 to 14 d postpartum. Rates of twins, stillbirth, milk fever, prolapsed uterus, retained placenta, primary metritis, displaced abomasum, ketonuria, and aciduria were 5.8, 6.3, 1.4, 3, 17.8, 36.1, 1.7, 30.4, and 29.5%, respectively. The risk for twins, milk fever, prolapsed uterus, displaced abomasum, ketonuria, and aciduria increased with parity, whereas that for stillbirth and metritis was higher in heifers than in cows. Stillbirth, retained placenta, metritis, displaced abomasum, ketonuria, and aciduria were directly associated with birth of twins; prolapsed uterus and retained placenta with stillbirth; prolapsed uterus, retained placenta, and primary metritis with milk fever; displaced abomasum, ketonuria, and aciduria with retained placenta and with metritis; ketonuria and aciduria with displaced abomasum and aciduria with ketonuria. 相似文献
12.
Changes in milk production associated with occurrence of clinical diseases (dystocia, stillbirth, twin births, milk fever, retained placenta, displaced abomasum, limping due to foot lesions, metritis, ketosis, and mastitis) were investigated. Data were collected daily on 388 lactation. Stepwise least squares regression was used to evaluate existence of associations between diseases and six yield measures that characterized milk production in the first 119 d postpartum. Logistic regression was used to investigate whether milk yield 1 to 5 d in milk might be of use to detect cows with early postpartum metritis (less than 21 d after calving). Lower milk production to 5 d postpartum was associated with an increased risk of early postpartum metritis in the logistic regression model. Yield to 5 and to 21 d postpartum was lower in cases of stillbirth, retained placenta, and early postpartum metritis. Yield from 22 to 49 d postpartum remained lower in cows diagnosed with early postpartum metritis. Milk yield losses occurred during diagnosis and treatment of displaced abomasum and mastitis. Ketosis was associated with yield losses prior to and at treatment. Ketosis to 21 d in milk was also associated with lower production after treatment. Limping diagnosed in the first 49 d postpartum coincided with higher yield to 5 d, to 21 d, and after 49 d postpartum. 相似文献
13.
Incidences of ketosis, metritis, mastitis, and retained placenta were studied in Israeli Holstein cows calving between 2008 and 2017. These diseases were selected based on their economic impact. Ketosis, metritis, and retained placenta were scored dichotomously. Mastitis was scored as absent, a single occurrence during the lactation, or more than 1 occurrence. Ketosis and metritis were recorded during the first 21 d after calving, retained placenta during the first 5 d after calving, and mastitis up to 305 d in milk. The effects of herd-year-season, calving age, month of calving, gestation length, and occurrence of dystocia were included in the first-parity analysis models. All effects were significant for metritis and retained placenta. For ketosis, all effects were significant, except for gestation length. For mastitis, only the effects of herd-year-season and calving age were significant. Variance components were computed by the multitrait animal model. The 4 diseases were analyzed jointly based on first-parity records, and each disease was analyzed separately for parities 1 to 3 with the different parities considered separate traits. The 4 disease traits in first parity were also analyzed jointly with the 6 major traits included in the Israeli breeding index: milk, fat, and protein production; somatic cell score; female fertility; and longevity. Heritability was highest for metritis and lowest for mastitis, but all heritabilities were <0.07, similar to previous studies. For all 4 diseases, genetic correlations among the first 3 parities were >0.65, and all residual correlations were <0.07. Selection of herd-years assumed to have more accurate recording of mastitis did not result in higher heritability estimates. Genetic correlations between the disease traits and milk, fat, and protein production were economically unfavorable, while correlations between the disease traits and somatic cell score, female fertility, and longevity were economically favorable. Expected genetic changes in the disease traits after 10 yr of selection with the current Israeli breeding index were all <1%, except for ketosis, which was predicted to increase by 1.5%. Inclusion of these traits in a proposed index with the disease traits constituting 7% of the index would result in only marginal improvements for the disease traits and adversely affect genetic gain for fat and protein production. Thus, inclusion of these traits in the breeding index cannot be justified economically. 相似文献
14.
The objective of this study was to determine the feasibility of genetic selection for health traits in dairy cattle using data recorded in on-farm herd management software programs. Data regarding displaced abomasum (DA), ketosis (KET), mastitis (MAST), lameness (LAME), cystic ovaries (CYST), and metritis (MET) were collected between January 1, 2001 and December 31, 2003 in herds using Dairy Comp 305, DHI-Plus, or PCDART herd management software programs. All herds in this study were either participants in the Alta Genetics (Watertown, WI) Advantage progeny testing program or customers of the Dairy Records Management Systems (Raleigh, NC) processing center. Minimum lactation incidence rates were applied to ensure adequate reporting of these disorders within individual herds. After editing, DA, KET, MAST, LAME, CYST, and MET data from 75,252 (313), 52,898 (250), 105,029 (429), 50,611 (212), 65,080 (340), and 97,318 (418) cows (herds) remained for analysis. Average lactation incidence rates were 0.03, 0.10, 0.20, 0.10, 0.08, and 0.21 for DA, KET, MAST, LAME, CYST, and MET (including retained placenta), respectively. Data for each disorder were analyzed separately using a threshold sire model that included a fixed parity effect and random sire and herd-year-season of calving effects; both first lactation and all lactation analyses were carried out. Heritability estimates from first lactation (all lactation) analyses were 0.18 (0.15) for DA, 0.11 (0.06) for KET, 0.10 (0.09) for MAST, 0.07 (0.06) for LAME, 0.08 (0.05) for CYST, and 0.08 (0.07) for MET. Corresponding heritability estimates for the pooled incidence rate of all diseases between calving and 50 d postpartum were 0.12 and 0.10 for the first and all lactation analyses, respectively. Mean differences in PTA for probability of disease between the 10 best and 10 worst sires were 0.034 for DA, 0.069 for KET, 0.130 for MAST, 0.054 for LAME, 0.039 for CYST, and 0.120 for MET. Based on the results of this study, it appears that genetic selection against common health disorders using data from on-farm recording systems is possible. 相似文献
15.
Dairy cows suffer blood Ca losses as lactation begins and might be affected by hypocalcemia in its clinical (total serum Ca concentration <1.50 mM) or subclinical form (total serum Ca concentration ≤2.14 mM). Several studies have suggested that hypocalcemia is associated with different health problems of the cow but results from different studies are not consistent. The objective of this study was to assess potential associations between subclinical hypocalcemia (SCHC) and displaced abomasum, intramammary infections, metritis, retained placenta, and ketosis. Also, the associations between SCHC and milk yield and reproductive function were evaluated. After discarding cows (32) with clinical hypocalcemia, a total of 764 cows from 6 different commercial farms were enrolled in this study. Blood samples were collected at 24 to 48 h postcalving and analyzed for total Ca concentration. Odds ratios of the different afflictions potentially associated with SCHC were calculated. Seventy-eight percent of the analyzed cows incurred SCHC. The occurrence of displaced abomasum, ketosis, retained placenta, and metritis was 3.7, 5.5, 3.4, and 4.3 times more likely, respectively, in cows that had SCHC than in cows with normocalcemia. Furthermore, the risk of incurring retained placenta or metritis increased in multiparous cows as serum Ca concentrations decreased compared with that in primiparous cows. Normocalcemic cows, independent of parity, were more likely to show their first estrus sooner after calving than SCHC cows, but no correlation was found between SCHC and other reproductive parameters. Different serum Ca concentration cutoffs were identified for several postpartum afflictions (≤1.93, ≤2.05, ≤2.05, and ≤2.10 mM for ketosis, retained placenta, metritis, and displaced abomasum, respectively). In conclusion, SCHC, defined as serum Ca ≤2.14 mM, is a frequent illness affecting the majority of the dairy cows with important repercussions on health. However, if SCHC were to be used to predict postpartum disease, different serum Ca cutoff points are likely to be needed because best predictive cutoff values varied among postpartum ketosis, displaced abomasum, retained placenta, and metritis. 相似文献
16.
A meta-analysis of the impact of monensin in lactating dairy cattle. Part 3. Health and reproduction
A meta-analysis of the impact of monensin on health and reproductive outcomes in dairy cattle was conducted. A total of 16 papers were identified with sufficient data and quality to evaluate health and reproductive outcomes for monensin. The available trials provided approximately 9,500 cows with sufficient data for analysis. This provided good statistical power to examine the effects of monensin on health and reproduction. Over all the trials analyzed, monensin decreased the risk of ketosis [relative risk (RR) = 0.75], displaced abomasums (RR = 0.75), and mastitis (RR = 0.91). No significant effects of monensin were found for milk fever, lameness, dystocia, retained placenta, or metritis. Monensin had no effect on first-service conception risk (RR = 0.97) or days to pregnancy (hazard ratio = 0.93). However, the impact of monensin on dystocia, retained placenta, and metritis was heterogeneous for all 3 outcome measures and random effect models were utilized. Causes of the heterogeneity were explored with meta-regression. Days of treatment with monensin before calving increased the risk of dystocia. Delivery method of monensin influenced the incidence of retained placenta and metritis, with risk being lower with controlled release capsule treatment compared with delivery in either topdress or in a total mixed ration. Days of treatment before calving also influenced retained placenta with an increase in risk with more days treated before calving. Improvements in ketosis, displaced abomasums, and mastitis with monensin were achieved. Exposure to prolonged treatment in the dry period with monensin may increase the risk of dystocia and retained placenta. 相似文献
17.
The aim of this study was to determine the prevalence, major management systems, and fresh cow clinical conditions associated with ketosis in western European dairy herds. A total of 131 dairies were enrolled in Germany, France, Italy, the Netherlands, and the United Kingdom during 2011 to 2012. A milk-based test for ketones (Keto-Test; Sanwa Kagaku Kenkyusho Co. Ltd., Nagoya, Japan; distributed by Elanco Animal Health, Antwerp, Belgium) was used for screening cows between d 7 and 21 after calving and ketosis was defined as a Keto-Test ≥100 µmol/L. Study cows were observed for clinical disease up to 35 d postcalving. Multivariate analysis (generalized estimating equation logistic regression) was performed to determine country, farm, management, feed, and cow factors associated with ketosis and to determine associations between ketosis and fresh cow diseases. Thirty-nine percent of the cows were classified as having ketosis. The herd average of ketosis was 43% in Germany, 53% in France, 31% in Italy, 46% in the Netherlands, and 31% in the United Kingdom. Of the 131 farms, 112 (85%) had 25% or more of their fresh cows resulting as positive for ketosis. Clinical ketosis was not reported in most farms and the highest level of clinical ketosis reported was 23%. The risks of ketosis were significantly lower in Italy and the United Kingdom compared with France, the Netherlands, and Germany. Larger herd size was associated with a decreased risk of ketosis. The farms that fed partially mixed rations had 1.5 times higher odds of ketosis than those that fed total mixed rations. Cows that calved in April to June had the highest odds of ketosis, with about twice as high odds compared with cows that calved in July to September. The cows that calved in January to March tended to have 1.5 times higher risk of ketosis compared with cows that calved in July to September. The odds of ketosis in parity 2 and parity 3 to 7 was significantly higher (1.5 and 2.8 times higher, respectively) than the odds of ketosis in parity 1. The odds of ketosis was significantly smaller in parity 2 compared with parity 3 to 7. Ketosis was associated with significantly higher odds of all common fresh cow conditions: metritis, mastitis, displaced abomasum, clinical ketosis, lameness, and gastrointestinal disorders. Odds of ketosis in cows having had twins or dystocia were not increased, whereas higher odds of ketosis were observed in cows with milk fever or retained placenta. 相似文献
18.
Information from 7712 lactations of Holstein dairy cows was collected from 33 commercial herds around Ithaca, NY in the 3 yr from 1981 to 1983. The data were divided into subsets corresponding to lactation 1, lactation 2, and lactation 3 or greater. To estimate heritabilities of dystocia, retained placenta, metritis, ovarian cysts, milk fever, and mastitis, a mixed linear model (herd-year fixed and sire random effects) with 0 or 1 as the observed response was used. Variance components were estimated using Henderson's Method 3. The results show moderate heritabilities (.15 to .40) for dystocia, metritis, milk fever, and mastitis and low heritability (less than .12) for retained placenta and cystic ovaries. Genetic correlations between dystocia, retained placenta, metritis, and mastitis were moderate in size and positive, whereas cystic ovaries were correlated negatively with dystocia and retained placenta. A general reproductive health trait (dystocia, retained placenta, metritis, cystic ovaries, and milk fever combined in one trait) also was analyzed. The estimated heritability of this trait was .21, .11, and .00 for first calf heifers, second lactation cows, and older cows, respectively. 相似文献
19.
A total of 850 Holstein cows from 13 commercial dairy herds were involved in the present study to compare the effects of 2 different dry period (DP) management strategies on health and reproductive parameters. Cows were assigned to either a short (SDP; 35-d) or a conventional (CDP; 60-d) DP management within each herd, based on previous 305-d milk yield, parity (414 primiparous and 436 multiparous), and estimated calving interval. Cows assigned to CDP were fed a dry cow ration from dry-off until 21 d prepartum, and were then switched to a precalving ration. Cows assigned to SDP were fed the precalving ration throughout their DP. Rations were specific to each herd. A significant treatment × parity interaction was found for culling rate. Dry period management did not affect culling rate for second-lactation cows but a significantly higher culling rate occurred in multiparous CDP cows compared with SDP (42.6 vs. 31.6% ± 3.7 for CDP and SDP, respectively). Management used in the DP did not affect incidence of severe ketosis, displaced abomasum, milk fever, and mastitis, although incidence of these metabolic disorders were lower in second-lactation than third- or greater-lactation cows. The incidence of mild ketosis (evaluated by milk ketone concentration) was lower following SDP, probably as a result of better energy balance. On the other hand, the incidence of retained placenta was higher in multiparous cows assigned to SDP, but the reason for this increase remains unclear. Nevertheless, this did not lead to increased incidence of metritis. Moreover, DP management did not influence reproductive measures, including days in milk at first breeding, number of breedings per conception, as well as conception rates at first and second services. Regarding days open, overall, all 13 herds were not significantly affected by treatment, but 1 herd clearly showed opposite results to the 12 others. Our results indicate that a short DP management strategy could facilitate transition from one lactation to the next by decreasing the incidence of mild ketosis, with no major negative effects on other health parameters and reproduction. The variation in results observed among herds suggests that other management practices influence the response observed following a short or conventional DP, emphasizing the need for other field studies. 相似文献