一款含发酵组合物的护肤品抗衰功效评价研究

对一款含发酵组合物的护肤品进行抗衰功效评价研究和消费者主观评测,评价发酵组合物作为抗衰剂在护肤品中的抗衰性能。研究了发酵组合物中的核心抗衰成分ALPHA-KG对SPT的mRNA表达促进作用。选择30名25～45岁的女性受试者作为研究对象,采用随机双盲安慰剂对照的实验设计,测试0 D,14 D,28 D时,Primos测试前额、外眼角、鼻唇沟的皱纹,VISIA-CR全脸图像,临床评估,收集受试者主观评价结果。结果显示,与不含发酵组合物的基质相比,含发酵组合物的基质对皮肤有紧致效果,对于前额、外眼角、鼻唇沟、眼下、全脸细纹均有改善;消费者主观评估,90%的受试者认为该护肤品有细化毛孔、改善面部皱纹、提高皮肤弹性等功效。     

含MER-SCEX的头皮洗护产品组对头皮和面部抗衰功效评价

验证了MER-SCEX具有调节头皮微生态平衡达到头皮抗衰功效,对含有MER-SCEX的头皮洗护产品组采用测试头皮水分含量、头皮油脂含量、头皮发红、减少掉发的方法研究其抗衰功效,同时研究了头皮抗衰与面部肌肤抗衰老间的关联性,开展了头皮抗衰洗护产品组对于人面部抗衰的临床疗效研究。结果表明,该含MER-SCEX的头皮抗衰洗护产品组可以帮助头皮水油平衡,减少头皮炎症和发红,减少掉发;在4周的考察周期中发现头皮护理产品对于面部抗衰也有功效,证明该产品可紧致皮肤,针对性减少前额、外眼角、鼻泪沟部位的皱纹,提高皮肤弹性,细化毛孔等功效。     

一种天然植物组方的舒缓修护功效

为了测试一种天然植物组方的舒缓、修护功效,采用UVB紫外光诱导HaCaT细胞产生炎症因子,将不同质量分数的天然植物组方与其进行共培养,测试组方的抗炎效果;通过人体测试,对受试者使用前后皮肤的红斑指数、黑素指数、经皮失水率进行测试。结果显示,制备的天然植物组方具有较好的抗炎作用,对于TNF-α、IL-1α、IL-6均具有明显的抑制作用;使用13天后,受试者皮肤红斑指数、黑素指数、经皮失水率较使用前皆有改善,差异有统计学意义（P <0.05）。13天的试验期间未出现任何皮肤不良反应,表明其具有良好的安全性,适用于敏感性皮肤人群。     

一种中草药复合物化妆品的祛痘抗炎功效评价研究

研究了5种中草药复合醇提取物和含有该5种中草药复合醇提物的祛痘精华液的安全性和功效性,用痤疮丙酸杆菌进行体外抑菌实验;用脂多糖LPS诱导RAW264.7小鼠巨噬细胞建立的炎症模型,进行抗炎功效测试;同时用红细胞溶血测试进行刺激性评估;最后通过含有该5种中草药复合提取物的祛痘精华液进行人体斑贴安全性测试及祛痘功效测试并与市售某款含1%水杨酸有效成分的热销祛痘产品进行对比。结果显示含有此5种中草药复合醇提物的祛痘精华液安全、温和且具有祛痘抗炎作用。     

一款护肤组合物对婴幼儿皮肤屏障修复功效的评价研究

目的：研究一款模拟胎脂脂质成分设计的护肤组合物对婴幼儿皮肤屏障的改善效果。方法：采用婴儿原代角质细胞组织培养的3D皮肤模型进行测评,选用十二烷基硫酸钠作为刺激物,构建体外皮肤损伤阳性模型。在损伤模型上持续使用14 d组合物,研究皮肤屏障功能指标[经皮失水值（TWEL）、经皮电阻值（TER）、组织形态]的变化。结果：使用该组合物14 d后,经皮失水值明显下降,且优于阳性对照组;经皮电阻值明显上升且优于阳性对照组;相比阳性对照组的组织形态,产品组的角质层疏松程度缓解,荧光黄染料数量减少。结论：该组合物具有重建皮肤屏障的功效,有望作为一款化妆品原料添加在婴童护肤品中使用。     

铁皮石斛提取物在化妆品中的应用

为了探讨铁皮石斛提取物在化妆品中的应用,通过清除ABTS自由基试验、酪氨酸酶活性抑制试验、封闭性斑贴测试、临床功效测试,验证铁皮石斛提取物的效果。结果显示,铁皮石斛提取物对ABTS自由基有较好的清除效果,半数清除浓度值(IC₅₀)为(6.84±0.94)mg/mL。对酪氨酸酶具有较好的抑制作用,IC₅₀为(8.57±0.81) mg/mL。根据封闭性斑贴测试,显示含质量分数10%铁皮石斛提取物的精华液无刺激性。32名受试者使用6周后结果表明,与使用前相比皮肤含水量增长15.34%、经皮失水减少17.84%、皮肤黄度减少5.46%、透亮度增加5.67%,均有显著改善(P<0.01)。因此,铁皮石斛提取物具有较强抗氧化和抑制酪氨酸酶功效,温和安全,长期使用含质量分数10%铁皮石斛提取物的精华液能达到保湿、保护皮肤屏障、祛黄、美白功效,值得临床推广和使用。     

LYCD制备及保湿抗衰老功效评价

本文研究了生产LYCD的最佳条件,并对LYCD乳液的保湿、抗衰老功效进行了人体测试,通过水合度、皮肤弹性、透皮失水率（TEWL）及皮肤更新速率的研究,结果表明：LYCD是一种安全有效的新型保湿抗衰老化妆品。     

复合多肽眼霜的延缓衰老功效测试与分析

对实验室自制的复合多肽眼霜进行临床功效测试,评价其抗衰效果。选取30名有效受试者为研究对象,选用无创仪器检测方法,监测对照组和测试组使用对应产品0,2,4和8周的皮肤角质层水分含量、弹性、粗糙度、皱纹体积和皱纹面积占比,以及受试者主观评价结果,并借助SPSS数据统计软件对实验结果进行统计分析。结果显示,复合多肽眼霜对皮肤角质层水分含量的提高、皮肤弹性的增强、眼部皱纹的减少具有显著作用,说明其具有良好的抗衰老功效。     

含有1,3-β葡聚糖和植物提取复配物的保湿研究

研究测试1,3-β葡聚糖和植物提取复配物在化妆品中的保湿作用以及运用,对比透明质酸的保湿功效.采用CM825型皮肤水分对测试仪,对两种添加有该原料的产品进行皮肤水份含量测试.两种产品都具有相对不错的保湿作用,只含有0.05％1,3-β葡聚糖粉末和2％MF-800的精华液对于皮肤角质层的保湿能力强于只含有0.1％透明质酸...     

含有延缓皮肤衰老组合物的护肤品在面部皮肤年轻化中的应用效果

探讨含有一种专利延缓皮肤衰老组合物的精华液与面霜对面部皮肤年轻化的改善效果。将上述产品分别开展4周单一产品试验和12周组合产品试验。两类试验均为自身前后对照研究,分别通过仪器测试或医生评估,评价受试者皮肤光泽度、弹性、纹理等指标。结果显示,研究结束时,受试者相关评价指标均有改善,与基线数据相比差异具有统计学意义（P<0.05）。表明含该组合物的护肤品有助于促进面部皮肤年轻化。     

底座连接口特征参数对显示器后壳注塑质量的影响分析

在Moldflow分析软件的基础上,对显示器后壳进行仿真研究,以翘曲变形量为质量指标,结合控制变量法进行单因素变动实验,保持注射工艺参数不变,研究显示器后壳底座连接口对制品翘曲变形的影响.对数据进行图表分析,结果表明显示器后壳尺寸定位68.58 cm(27英寸)时,底座连接口选用圆形,连接口位置距离底边26 mm,尺寸...     

The role of the symmetry and the flexibility of the anion on the characteristics of the nanostructures and the viscosities of ionic liquids☆

The transport properties of ionic liquids (ILs) are crucial properties in view of their applications in electrochem-ical devices. One of the most important advantages of ILs is that their chemical–physical properties and conse-quently their bulk performances can be well tuned by optimizing the chemical structures of their ions. This will require elucidating the structural features of the ions that fundamentally determine the characteristics of the nanostructures and the viscosities of ILs. Here we showed for the first time that the“rigidity”, the order, and the compactness of the three-dimensional ionic networks generated by the anions and the cation head groups determine the formation and the sizes of the nanostructures in the apolar domains of ILs. We also found that the properties of ionic networks are governed by the conformational flexibility and the symmetry of the anion and/or the cation head group. The thermal stability of the nanostructures of ILs was shown to be con-trolled by the sensitivity of the conformational equilibrium of the anion to the change of temperature. We showed that the viscosity of ILs is strongly related to the symmetry and the flexibility of the constitute ions rather than to the size of the nanostructures of ILs. Therefore, the characteristics of the nanostructures and the viscosities of ILs, especially the thermal stability of the nanostructures, can be fine-tuned by tailoring the symmetry and the conformational flexibility of the anion.     

浅谈设备的性能与操作对胎面压出质量的影响

简要介绍了胎面压出的工作原理及工艺过程，对设备的配置及操作对胎面压出质量的影响进行了分析，并对压出过程中常见的质量缺陷、造成的原因以及解决措施提出了自己的见解。     

Investigation of the effects of fatty acids on the compressive strength of the concrete and the grindability of the cement

In cement industry, a great energy consumption has been observed during grinding of clinker. To reduce this consumption, some waste products have been used as grinding aids.In this investigation, the effects of sunflower oil (SO), oleic acid (OA), stearic acid (SA), myristic acid (MA) and lauric acid (LA) on the fineness and strength of the cement have been examined. These aids were added into clinker in certain ratios based on the cement clinker weight and the grinding has been done for a definite time at the same condition.All of the fatty acids used increased the fineness as compared with the cement without the grinding additives. SO and OA decreased the strength significantly, LA decreased it to a lesser extent and SA increased it definitely according to the common cement. But MA did not alter the strength of the cement as much as SA. In addition, the covering of the balls influences the grinding of cement clinker unfavourably.     

煤粉流动性对GSP气化炉气力输送的影响研究

针对GSP气化装置煤粉气力输送在试车阶段出现的煤粉锁斗下料不畅、发料罐输送性能不佳等问题,从原料煤性质和工业装置的改进方面出发,通过煤粉的流动性参数的测量与研究,分析出现上述工程问题可能的内在原因,并提出工业装置改进方法,为保证GSP煤粉气力输送工业装置的正常运行提供解决办法。     

关于建立火炸药安全数据库的探讨

由反映火炸药及其制品的危险性能和用于对它们的生产、储运系统进行安全评价数学模型出发,探讨了如何建立一个全面、实用的火炸药安全评估数据库。通过对此数据库内容、数据表示方法、数据搜索方法以及建立步骤的讨论,明确了该数据库的使用对象和主要功能。     

The effect of the length of the oxyethylene chain on the conductivity of the polyurethaneurea electrolyte

Polyurethaneureas (PUU), which were synthesized from 4,4′-diphenylmethane diisocyanate (MDI), poly(ethylene glycol) (PEG), and 3,5-diaminobanzoic acid (DABA), were used as polyelectrolytes in this study. Differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FT-IR) were used to monitor the effect of the various kinds of PEG on the changes in morphology of PUU electrolytes corresponding to the concentration of lithium perchlorate (LiClO₄) dopants. The results of DSC and FT-IR indicate the Li⁺ ions coordinate with the soft and hard segments. Additionally, the crystallinity of the PEG soft segment and the ordered hydrogen-bonded urea carbonyl groups decreased with increasing salt concentration. Impedance spectroscopy (IS) measurements show that the PUU electrolyte with the high phase separation degree has the high ionic conductivity. The hard-segment T_g and the soft-segment T_m influence the conductivity behavior of polyelectrolytes with increasing measurement temperature.     

Effect of the drafting force on the strength of the bottom of the spinneret

In spinning basalt fibres, the drafting force is in the same range as in spinning of glass fibres. The effect of the drafting force can not be considered in the calculation for the strength and rigidity of the bottom of the spinneret. __________ Translated from Khimicheskie Volokna, No. 5, pp. 47–50, September–October, 2007.     

转子挤压组合凹模的应力分析

组合凹模的应力分析是一个非常复杂的问题，对其进行精确分析是解决模具寿命的关键。本文采用有限元分析软件Ansys对转子的组合凹模进行了分析，为转子组合凹模的优化设计提供了依据。