Metaheuristics with Deep Learning Empowered Biomedical Atherosclerosis Disease Diagnosis and Classification

Atherosclerosis diagnosis is an inarticulate and complicated cognitive process. Researches on medical diagnosis necessitate maximum accuracy and performance to make optimal clinical decisions. Since the medical diagnostic outcomes need to be prompt and accurate, the recently developed artificial intelligence (AI) and deep learning (DL) models have received considerable attention among research communities. This study develops a novel Metaheuristics with Deep Learning Empowered Biomedical Atherosclerosis Disease Diagnosis and Classification (MDL-BADDC) model. The proposed MDL-BADDC technique encompasses several stages of operations such as pre-processing, feature selection, classification, and parameter tuning. Besides, the proposed MDL-BADDC technique designs a novel Quasi-Oppositional Barnacles Mating Optimizer (QOBMO) based feature selection technique. Moreover, the deep stacked autoencoder (DSAE) based classification model is designed for the detection and classification of atherosclerosis disease. Furthermore, the krill herd algorithm (KHA) based parameter tuning technique is applied to properly adjust the parameter values. In order to showcase the enhanced classification performance of the MDL-BADDC technique, a wide range of simulations take place on three benchmarks biomedical datasets. The comparative result analysis reported the better performance of the MDL-BADDC technique over the compared methods.     

Fitness adaptive deer hunting-based region growing and recurrent neural network for melanoma skin cancer detection

This proposal aims to enhance the accuracy of a dermoscopic skin cancer diagnosis with the aid of novel deep learning architecture. The proposed skin cancer detection model involves four main steps: (a) preprocessing, (b) segmentation, (c) feature extraction, and (d) classification. The dermoscopic images initially subjected to a preprocessing step that includes image enhancement and hair removal. After preprocessing, the segmentation of lesion is deployed by an optimized region growing algorithm. In the feature extraction phase, local features, color morphology features, and morphological transformation-based features are extracted. Moreover, the classification phase uses a modified deep learning algorithm by merging the optimization concept into recurrent neural network (RNN). As the main contribution, the region growing and RNN improved by the modified deer hunting optimization algorithm (DHOA) termed as Fitness Adaptive DHOA (FA-DHOA). Finally, the analysis has been performed to verify the effectiveness of the proposed method.     

Automated Deep Learning Based Melanoma Detection and Classification Using Biomedical Dermoscopic Images

Melanoma remains a serious illness which is a common form of skin cancer. Since the earlier detection of melanoma reduces the mortality rate, it is essential to design reliable and automated disease diagnosis model using dermoscopic images. The recent advances in deep learning (DL) models find useful to examine the medical image and make proper decisions. In this study, an automated deep learning based melanoma detection and classification (ADL-MDC) model is presented. The goal of the ADL-MDC technique is to examine the dermoscopic images to determine the existence of melanoma. The ADL-MDC technique performs contrast enhancement and data augmentation at the initial stage. Besides, the k-means clustering technique is applied for the image segmentation process. In addition, Adagrad optimizer based Capsule Network (CapsNet) model is derived for effective feature extraction process. Lastly, crow search optimization (CSO) algorithm with sparse autoencoder (SAE) model is utilized for the melanoma classification process. The exploitation of the Adagrad and CSO algorithm helps to properly accomplish improved performance. A wide range of simulation analyses is carried out on benchmark datasets and the results are inspected under several aspects. The simulation results reported the enhanced performance of the ADL-MDC technique over the recent approaches.     

Optimal Deep Transfer Learning Model for Histopathological Breast CancerClassification

Earlier recognition of breast cancer is crucial to decrease the severity and optimize the survival rate. One of the commonly utilized imaging modalities for breast cancer is histopathological images. Since manual inspection of histopathological images is a challenging task, automated tools using deep learning (DL) and artificial intelligence (AI) approaches need to be designed. The latest advances of DL models help in accomplishing maximum image classification performance in several application areas. In this view, this study develops a Deep Transfer Learning with Rider Optimization Algorithm for Histopathological Classification of Breast Cancer (DTLRO-HCBC) technique. The proposed DTLRO-HCBC technique aims to categorize the existence of breast cancer using histopathological images. To accomplish this, the DTLRO-HCBC technique undergoes pre-processing and data augmentation to increase quantitative analysis. Then, optimal SqueezeNet model is employed for feature extractor and the hyperparameter tuning process is carried out using the Adadelta optimizer. Finally, rider optimization with deep feed forward neural network (RO-DFFNN) technique was utilized employed for breast cancer classification. The RO algorithm is applied for optimally adjusting the weight and bias values of the DFFNN technique. For demonstrating the greater performance of the DTLRO-HCBC approach, a sequence of simulations were carried out and the outcomes reported its promising performance over the current state of art approaches.     

Optimal Deep Learning Based Inception Model for Cervical Cancer Diagnosis

Prevention of cervical cancer becomes essential and is carried out by the use of Pap smear images. Pap smear test analysis is laborious and tiresome work performed visually using a cytopathologist. Therefore, automated cervical cancer diagnosis using automated methods are necessary. This paper designs an optimal deep learning based Inception model for cervical cancer diagnosis (ODLIM-CCD) using pap smear images. The proposed ODLIM-CCD technique incorporates median filtering (MF) based pre-processing to discard the noise and Otsu model based segmentation process. Besides, deep convolutional neural network (DCNN) based Inception with Residual Network (ResNet) v2 model is utilized for deriving the feature vectors. Moreover, swallow swarm optimization (SSO) based hyperparameter tuning process is carried out for the optimal selection of hyperparameters. Finally, recurrent neural network (RNN) based classification process is done to determine the presence of cervical cancer or not. In order to showcase the improved diagnostic performance of the ODLIM-CCD technique, a series of simulations occur on benchmark test images and the outcomes highlighted the improved performance over the recent approaches with a superior accuracy of 0.9661.     

Evolutionary Algorithsm with Machine Learning Based Epileptic Seizure Detection Model

Machine learning (ML) becomes a familiar topic among decision makers in several domains, particularly healthcare. Effective design of ML models assists to detect and classify the occurrence of diseases using healthcare data. Besides, the parameter tuning of the ML models is also essential to accomplish effective classification results. This article develops a novel red colobuses monkey optimization with kernel extreme learning machine (RCMO-KELM) technique for epileptic seizure detection and classification. The proposed RCMO-KELM technique initially extracts the chaotic, time, and frequency domain features in the actual EEG signals. In addition, the min-max normalization approach is employed for the pre-processing of the EEG signals. Moreover, KELM model is used for the detection and classification of epileptic seizures utilizing EEG signal. Furthermore, the RCMO technique was utilized for the optimal parameter tuning of the KELM technique in such a way that the overall detection outcomes can be considerably enhanced. The experimental result analysis of the RCMO-KELM technique has been examined using benchmark dataset and the results are inspected under several aspects. The comparative result analysis reported the better outcomes of the RCMO-KELM technique over the recent approaches with the of 0.956.     

Diagnosis of Various Skin Cancer Lesions Based on Fine-Tuned ResNet50 Deep Network

With the massive success of deep networks, there have been significant efforts to analyze cancer diseases, especially skin cancer. For this purpose, this work investigates the capability of deep networks in diagnosing a variety of dermoscopic lesion images. This paper aims to develop and fine-tune a deep learning architecture to diagnose different skin cancer grades based on dermatoscopic images. Fine-tuning is a powerful method to obtain enhanced classification results by the customized pre-trained network. Regularization, batch normalization, and hyperparameter optimization are performed for fine-tuning the proposed deep network. The proposed fine-tuned ResNet50 model successfully classified 7-respective classes of dermoscopic lesions using the publicly available HAM10000 dataset. The developed deep model was compared against two powerful models, i.e., InceptionV3 and VGG16, using the Dice similarity coefficient (DSC) and the area under the curve (AUC). The evaluation results show that the proposed model achieved higher results than some recent and robust models.     

A serialized classification method for pulmonary nodules based on lightweight cascaded convolutional neural network-long short-term memory

Computer Assisted Diagnosis (CAD) is an effective method to detect lung cancer from computed tomography (CT) scans. The development of artificial neural network makes CAD more accurate in detecting pathological changes. Due to the complexity of the lung environment, the existing neural network training still requires large datasets, excessive time, and memory space. To meet the challenge, we analysis 3D volumes as serialized 2D slices and present a new neural network structure lightweight convolutional neural network (CNN)-long short-term memory (LSTM) for lung nodule classification. Our network contains two main components: (a) optimized lightweight CNN layers with tiny parameter space for extracting visual features of serialized 2D images, and (b) LSTM network for learning relevant information among 2D images. In all experiments, we compared the training results of several models and our model achieved an accuracy of 91.78% for lung nodule classification with an AUC of 93%. We used fewer samples and memory space to train the model, and we achieved faster convergence. Finally, we analyzed and discussed the feasibility of migrating this framework to mobile devices. The framework can also be applied to cope with the small amount of training data and the development of mobile health device in future.     

Multiview convolutional neural networks for lung nodule classification

To find a better way to screen early lung cancer, motivated by the great success of deep learning, we empirically investigate the challenge of classifying lung nodules in computed tomography (CT) in an end‐to‐end manner. Multi‐view convolutional neural networks (MV‐CNN) are proposed in this article for lung nodule classification. Unlike the traditional CNNs, a MV‐CNN takes multiple views of each entered nodule. We carry out a binary classification (benign and malignant) and a ternary classification (benign, primary malignant, and metastatic malignant) using the Lung Image Database Consortium and Image Database Resource Initiative database. The results show that, for binary or ternary classifications, the multiview strategy produces higher accuracy than the single view method, even for cases that are over‐fitted. Our model achieves an error rate of 5.41 and 13.91% for binary and ternary classifications, respectively. Finally, the receiver operating characteristic curve and t‐distributed stochastic neighbor embedding algorithm are used to analyze the models. The results reveal that the deep features learned by the model proposed in this article have a higher separability than features from the image space and the multiview strategies; therefore, researchers can get better representation. © 2017 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 27, 12–22, 2017     

Improved Metaheuristics with Machine Learning Enabled Medical Decision Support System

Smart healthcare has become a hot research topic due to the contemporary developments of Internet of Things (IoT), sensor technologies, cloud computing, and others. Besides, the latest advances of Artificial Intelligence (AI) tools find helpful for decision-making in innovative healthcare to diagnose several diseases. Ovarian Cancer (OC) is a kind of cancer that affects women’s ovaries, and it is tedious to identify OC at the primary stages with a high mortality rate. The OC data produced by the Internet of Medical Things (IoMT) devices can be utilized to differentiate OC. In this aspect, this paper introduces a new quantum black widow optimization with a machine learning-enabled decision support system (QBWO-MLDSS) for smart healthcare. The primary intention of the QBWO-MLDSS technique is to detect and categorize the OC rapidly and accurately. Besides, the QBWO-MLDSS model involves a Z-score normalization approach to pre-process the data. In addition, the QBWO-MLDSS technique derives a QBWO algorithm as a feature selection to derive optimum feature subsets. Moreover, symbiotic organisms search (SOS) with extreme learning machine (ELM) model is applied as a classifier for the detection and classification of ELM model, thereby improving the overall classification performance. The design of QBWO and SOS for OC detection and classification in the smart healthcare environment shows the study’s novelty. The experimental result analysis of the QBWO-MLDSS model is conducted using a benchmark dataset, and the comparative results reported the enhanced outcomes of the QBWO-MLDSS model over the recent approaches.     

Multimodal brain tumor detection and classification using deep saliency map and improved dragonfly optimization algorithm

In the last decade, there has been a significant increase in medical cases involving brain tumors. Brain tumor is the tenth most common type of tumor, affecting millions of people. However, if it is detected early, the cure rate can increase. Computer vision researchers are working to develop sophisticated techniques for detecting and classifying brain tumors. MRI scans are primarily used for tumor analysis. We proposed an automated system for brain tumor detection and classification using a saliency map and deep learning feature optimization in this paper. The proposed framework was implemented in stages. In the initial phase of the proposed framework, a fusion-based contrast enhancement technique is proposed. In the following phase, a tumor segmentation technique based on saliency maps is proposed, which is then mapped on original images based on active contour. Following that, a pre-trained CNN model named EfficientNetB0 is fine-tuned and trained in two ways: on enhanced images and on tumor localization images. Deep transfer learning is used to train both models, and features are extracted from the average pooling layer. The deep learning features are then fused using an improved fusion approach known as Entropy Serial Fusion. The best features are chosen in the final step using an improved dragonfly optimization algorithm. Finally, the best features are classified using an extreme learning machine (ELM). The experimental process is conducted on three publically available datasets and achieved an improved accuracy of 95.14, 94.89, and 95.94%, respectively. The comparison with several neural nets shows the improvement of proposed framework.     

Compact Bat Algorithm with Deep Learning Model for Biomedical EEG EyeState Classification

Electroencephalography (EEG) eye state classification becomes an essential tool to identify the cognitive state of humans. It can be used in several fields such as motor imagery recognition, drug effect detection, emotion categorization, seizure detection, etc. With the latest advances in deep learning (DL) models, it is possible to design an accurate and prompt EEG EyeState classification problem. In this view, this study presents a novel compact bat algorithm with deep learning model for biomedical EEG EyeState classification (CBADL-BEESC) model. The major intention of the CBADL-BEESC technique aims to categorize the presence of EEG EyeState. The CBADL-BEESC model performs feature extraction using the ALexNet model which helps to produce useful feature vectors. In addition, extreme learning machine autoencoder (ELM-AE) model is applied to classify the EEG signals and the parameter tuning of the ELM-AE model is performed using CBA. The experimental result analysis of the CBADL-BEESC model is carried out on benchmark results and the comparative outcome reported the supremacy of the CBADL-BEESC model over the recent methods.     

Optimized Convolutional Neural Network Models for Skin Lesion Classification

Skin cancer is one of the most severe diseases, and medical imaging is among the main tools for cancer diagnosis. The images provide information on the evolutionary stage, size, and location of tumor lesions. This paper focuses on the classification of skin lesion images considering a framework of four experiments to analyze the classification performance of Convolutional Neural Networks (CNNs) in distinguishing different skin lesions. The CNNs are based on transfer learning, taking advantage of ImageNet weights. Accordingly, in each experiment, different workflow stages are tested, including data augmentation and fine-tuning optimization. Three CNN models based on DenseNet-201, Inception-ResNet-V2, and Inception-V3 are proposed and compared using the HAM10000 dataset. The results obtained by the three models demonstrate accuracies of 98%, 97%, and 96%, respectively. Finally, the best model is tested on the ISIC 2019 dataset showing an accuracy of 93%. The proposed methodology using CNN represents a helpful tool to accurately diagnose skin cancer disease.     

Deep learning technology for improving cancer care in society: New directions in cancer imaging driven by artificial intelligence

The goal of this study is to show emerging applications of deep learning technology in cancer imaging. Deep learning technology is a family of computational methods that allow an algorithm to program itself by learning from a large set of examples that demonstrate the desired behavior. Applications of deep learning technology to cancer imaging can assist pathologists in the detection and classification of cancer in the early stages of its development to allow patients to have appropriate treatments that can increase their survival. Statistical analyses and other analytical approaches, based on data of ScienceDirect (a source for scientific research), suggest that the sharp increase of the studies of deep learning technology in cancer imaging seems to be driven by high rates of mortality of some types of cancer (e.g., lung and breast) in order to solve consequential problems of a more accurate detection and characterization of cancer types to apply efficient anti-cancer therapies. Moreover, this study also shows sources of the trajectories of deep learning technology in cancer imaging at level of scientific subject areas, universities and countries with the highest scientific production in these research fields. This new technology, in accordance with Amara's law, can generate a shift of technological paradigm for diagnostic assessment of any cancer type and disease. This new technology can also generate socioeconomic benefits for poor regions because they can send digital images to labs of other developed regions to have diagnosis of cancer types, reducing as far as possible current gap in healthcare sector among different regions.     

Sailfish Optimizer with EfficientNet Model for Apple Leaf Disease Detection

Recent developments in digital cameras and electronic gadgets coupled with Machine Learning (ML) and Deep Learning (DL)-based automated apple leaf disease detection models are commonly employed as reasonable alternatives to traditional visual inspection models. In this background, the current paper devises an Effective Sailfish Optimizer with EfficientNet-based Apple Leaf disease detection (ESFO-EALD) model. The goal of the proposed ESFO-EALD technique is to identify the occurrence of plant leaf diseases automatically. In this scenario, Median Filtering (MF) approach is utilized to boost the quality of apple plant leaf images. Moreover, SFO with Kapur's entropy-based segmentation technique is also utilized for the identification of the affected plant region from test image. Furthermore, Adam optimizer with EfficientNet-based feature extraction and Spiking Neural Network (SNN)-based classification are employed to detect and classify the apple plant leaf images. A wide range of simulations was conducted to ensure the effective outcomes of ESFO-EALD technique on benchmark dataset. The results reported the supremacy of the proposed ESFO-EALD approach than the existing approaches.     

Morphological feature extraction and KNG-CNN classification of CT images for early lung cancer detection

Lung cancer is a dangerous disease causing death to individuals. Currently precise classification and differential diagnosis of lung cancer is essential with the stability and accuracy of cancer identification is challenging. Classification scheme was developed for lung cancer in CT images by Kernel based Non-Gaussian Convolutional Neural Network (KNG-CNN). KNG-CNN comprises of three convolutional, two fully connected and three pooling layers. Kernel based Non-Gaussian computation is used for the diagnosis of false positive or error encountered in the work. Initially Lung Image Database Consortium image collection (LIDC-IDRI) dataset is used for input images and a ROI based segmentation using efficient CLAHE technique is carried as preprocessing steps, enhancing images for better feature extraction. Morphological features are extracted after the segmentation process. Finally, KNG-CNN method is used for effectual classification of tumour > 30mm. An accuracy of 87.3% was obtained using this technique. This method is effectual for classifying the lung cancer from the CT scanned image.     

Automated Artificial Intelligence Empowered White Blood Cells ClassificationModel

White blood cells (WBC) or leukocytes are a vital component of the blood which forms the immune system, which is accountable to fight foreign elements. The WBC images can be exposed to different data analysis approaches which categorize different kinds of WBC. Conventionally, laboratory tests are carried out to determine the kind of WBC which is erroneous and time consuming. Recently, deep learning (DL) models can be employed for automated investigation of WBC images in short duration. Therefore, this paper introduces an Aquila Optimizer with Transfer Learning based Automated White Blood Cells Classification (AOTL-WBCC) technique. The presented AOTL-WBCC model executes data normalization and data augmentation process (rotation and zooming) at the initial stage. In addition, the residual network (ResNet) approach was used for feature extraction in which the initial hyperparameter values of the ResNet model are tuned by the use of AO algorithm. Finally, Bayesian neural network (BNN) classification technique has been implied for the identification of WBC images into distinct classes. The experimental validation of the AOTL-WBCC methodology is performed with the help of Kaggle dataset. The experimental results found that the AOTL-WBCC model has outperformed other techniques which are based on image processing and manual feature engineering approaches under different dimensions.     

Intelligent Feature Selection with Deep Learning Based Financial Risk Assessment Model

Due to global financial crisis, risk management has received significant attention to avoid loss and maximize profit in any business. Since the financial crisis prediction (FCP) process is mainly based on data driven decision making and intelligent models, artificial intelligence (AI) and machine learning (ML) models are widely utilized. This article introduces an intelligent feature selection with deep learning based financial risk assessment model (IFSDL-FRA). The proposed IFSDL-FRA technique aims to determine the financial crisis of a company or enterprise. In addition, the IFSDL-FRA technique involves the design of new water strider optimization algorithm based feature selection (WSOA-FS) manner to an optimum selection of feature subsets. Moreover, Deep Random Vector Functional Link network (DRVFLN) classification technique was applied to properly allot the class labels to the financial data. Furthermore, improved fruit fly optimization algorithm (IFFOA) based hyperparameter tuning process is carried out to optimally tune the hyperparameters of the DRVFLN model. For enhancing the better performance of the IFSDL-FRA technique, an extensive set of simulations are implemented on benchmark financial datasets and the obtained outcomes determine the betterment of IFSDL-FRA technique on the recent state of art approaches.     

Feature Subset Selection with Artificial Intelligence-Based Classification Model for Biomedical Data

Recently, medical data classification becomes a hot research topic among healthcare professionals and research communities, which assist in the disease diagnosis and decision making process. The latest developments of artificial intelligence (AI) approaches paves a way for the design of effective medical data classification models. At the same time, the existence of numerous features in the medical dataset poses a curse of dimensionality problem. For resolving the issues, this article introduces a novel feature subset selection with artificial intelligence based classification model for biomedical data (FSS-AICBD) technique. The FSS-AICBD technique intends to derive a useful set of features and thereby improve the classifier results. Primarily, the FSS-AICBD technique undergoes min-max normalization technique to prevent data complexity. In addition, the information gain (IG) approach is applied for the optimal selection of feature subsets. Also, group search optimizer (GSO) with deep belief network (DBN) model is utilized for biomedical data classification where the hyperparameters of the DBN model can be optimally tuned by the GSO algorithm. The choice of IG and GSO approaches results in promising medical data classification results. The experimental result analysis of the FSS-AICBD technique takes place using different benchmark healthcare datasets. The simulation results reported the enhanced outcomes of the FSS-AICBD technique interms of several measures.