电化学方法制备磷酸钙生物陶瓷镀层

电化学方法是制备磷酸钙生物陶瓷镀层的重要方法之一,具有其它方法无可比拟的优点。基于电化学原理有三种技术可用于制备生物活性陶瓷镀层一电沉积技术、电化学复合共沉积技术和电泳沉积技术。本文对这三种技术用于制备磷酸钙生物陶瓷镀层的原理、特点及应用作了评述。     

电沉积法制备磷酸钙生物活性陶瓷涂层

综述了用电沉积法在金属生物材料表面涂敷磷酸钙生物活性陶瓷的工艺，分析了电沉积工艺的特点，并介绍了制备金属－羟基磷灰石复合涂层的复合电沉积工艺。     

碳/碳复合材料表面声电沉积磷酸钙生物活性涂层过程建模

声电沉积是一种非线性涂层制备生物活性磷酸钙的新方法,然而目前关于该方法的机理还不清楚。文章采用声电沉积法在C/C表面制备了磷酸钙涂层,结合实验过程,给出了声电沉积磷酸钙涂层的物理模型,并给出了沉积过程中受扩散过程控制的动力学方程,设计了相应的实验,证实阴极声电沉积生物活性钙磷速率主要由溶液中的离子向阴极表面扩散所控制。     

多孔磷酸钙生物陶瓷的成型与烧结

研究了制备作人工骨材料的磷酸钙生物活性多孔陶瓷的成型条件和烧结条件,建立了制备多孔磷酸钙生物陶瓷的适宜工艺,制得了三种多孔磷酸钙生物陶瓷ｐ－β－ＴＣＰ,ｐ－ＨＡ和ｐ－ＨＡ／ＴＣＰ。     

钛合金—氧化铝—磷酸钙复合材料

以自蔓高温合成的钛合金氧化铝复合前驱体，添加具有生物活性的磷酸钙陶瓷粉末，热压烧结制备的钛合金－氧化铝－磷酸钙多相复合材料，具有较高的机械强度，并有良好的生物相容性和生物降解性，在生物医学工程中具有应用前景，本文对其制备工艺和性能测量均作了较为详细的介绍。     

最新磷酸钙、亚磷酸盐专利文摘

可在体内降解成孔的磷酸钙骨水泥的制备方法;等离子喷涂羟基磷灰石涂层后处理方法;生物活性硅酸三钙自固化材料、制备方法及用途；纳米结构化可降解生物医用复合材料及其制备方法；药物载体磷酸钙纳米线及其制备方法；抗菌过磷酸钙及其制作方法。[第一段]     

微波烧结制备碳酸化多孔羟基磷灰石纳米陶瓷

采用活性炭辅助微波烧结的方法制备多孔碳酸化磷酸钙纳米陶瓷。通过考察多孔陶瓷坯体在不同烧结温度的线收缩率和抗压强度得到合适的烧结温度。1000℃微波烧结得到多孔碳酸化磷酸钙纳米陶瓷：抗压强度约为2.5MPa,平均晶粒尺寸约为132nm,孔隙率约为75%。与常规陶瓷相比,该种陶瓷抗压强度相当、晶粒尺寸更小并且微观结构更均匀...     

微波烧结法制备TCP/TTCP复合生物陶瓷材料的研究

采用微波烧结方法制备TCP/TTCP复合磷酸钙生物陶瓷材料,以四水硝酸钙(Ca(NO3)2·4H2O)和磷酸氢二铵((NH4)2HPO4)为初始原料制备磷酸三钙(TCP)和磷酸四钙(TTCP).研究了当代PCP/TTCP(物质的量)配比为1:1时,不同的烧结温度对复合钙磷陶瓷的结构和晶相的影响.对烧结后的样品在模拟体液中进行了浸泡实验,监测了浸泡过程中的pH值变化,通过扫描电镜、X射线衍射分析对浸泡后试样的结构和晶相的变化进行了分析.结果表明微波烧结制备的磷酸钙生物陶瓷的主晶相是HA,其结构均匀,致密度较好.且在1200℃下微波烧结HA能稳定存在,陶瓷具有良好的表面生物活性.浸泡溶液的pH值变化幅度小(在7.40～7.72之间),接近中性.     

专利信息

电磁炉陶瓷板及其制备方法;掺加氧化锌晶须制备磷酸钙基生物陶瓷的技术;β-TCP／HAP／Ca2P2O7多相多孔生物陶瓷的制备方法.     

生物活性β-硅酸二钙的喷雾干燥-微波快速烧结制备与性能表征

将微波烧结工艺与喷雾干燥技术相结合,成功探索了一种制备β-Ca2SiO4陶瓷的新工艺,考察了制备的β-Ca2SiO4陶瓷的生物活性。用扫描电子显微镜、X射线衍射和红外光谱分析对前驱体和β-Ca2SiO4陶瓷进行了表征。结果表明:前驱体为四水硝酸钙、硝酸钙及硅溶胶的混合物,由80～300nm的粒子团聚而成;新工艺制备的β-Ca2SiO4陶瓷可在30min内于900℃烧成,并且不发生β→γ的相变。通过模拟体液浸泡实验考察了制备的β-Ca2SiO4陶瓷的生物活性,结果表明:制备的β-Ca2SiO4陶瓷,通过模拟体液浸泡可在72h内诱导类骨磷灰石沉积在表面,显示出良好的生物活性。由此得出结论:采用喷雾干燥-微波烧结工艺制备β-Ca2SiO4陶瓷,与传统工艺相比,能显著降低烧结温度,缩短烧结所需时间,并且制备的β-Ca2SiO4陶瓷具有良好的生物活性。     

电泳沉积功能陶瓷涂层技术

本文评述了功能陶瓷悬浮液的稳定性、电泳沉积技术原理、以及该技术在制备生物陶瓷、超导陶瓷、铁电陶瓷、耐磨耐高温陶瓷等功能陶瓷涂层方面的应用。讨论了电流、电压、分散介质及陶瓷本身特性等因素对电泳沉积过程和功能陶瓷沉积层性能的影响。     

Bioactive glass coating using aerosol deposition

This work demonstrates the successful deposition of bioactive glass (BG) 45S5 coatings on various metallic and ceramic substrates at room temperature under low vacuum condition by using aerosol deposition (AD). This room temperature and particle impact consolidation-based deposition method enabled us to deposit well-adhered and dense BG coatings directly on metallic and ceramic substrates. In vitro tests with human osteoblast-like cells on substrates with a 45S5 BG coating demonstrated high cell activity on the surfaces. All tested materials exhibited high in vitro biocompatibility as no inhibition in cell proliferation could be observed. The utilization of AD process for achieving non-crystalline BG coatings is promising for practical bio-medical applications, e.g., bioactive coatings on bioinert metallic and ceramic substrates.     

在非水溶液体系中电泳沉积Ti6Al4V/BG/HA梯度涂层

本工作的目的是探索制备钛合金表面生物活性梯度涂层的新方法 ,提高涂层的结合强度及稳定性 .通过诱导羟基磷灰石 (HA)在生物玻璃 (BG)颗粒表面的结晶 ,改变了生物玻璃表面的带电特性 ;采用电泳沉积 (EPD)法 ,在非水溶液体系中实现了BG和HA在阴极Ti6Al4V基体上的共沉积 ,经烧结获得了生物活性梯度陶瓷涂层 ,得到了一种制备生物活性梯度陶瓷涂层的新工艺 .用XRD对涂层的相组成进行了定性分析 ,结果表明涂层由HA ,榍石和玻璃组成 ;采用粘结拉伸法测定的涂层与基体结合强度大于 18MPa,用SEM观察涂层表面及断面的形貌 ,可见涂层表面较为平整 ,没有明显的裂纹 ;涂层与基体结合紧密 ,且存在一明显的界面梯度区域 .     

A study of the electrophoretic deposition of bioactive glass-chitosan composite coating

Bioactive glass is coated on implant's surface to improve corrosion resistance and osseointegration, when placed in the body. Bioactive glass particles were synthesized through a sol-gel process and deposited along with chitosan to form a composite coating on a stainless steel substrate using electrophoretic deposition technique. Stable suspensions of chitosan-bioactive glass were prepared using bioactive glass particles (<1 μm) and 0.5 g/l chitosan solution. The influence of ethanol-water ratio on deposition yield was investigated. For all process conditions, best results were achieved with suspension of 30 vol% water in ethanol-water containing 2 g/l bioactive glass. FTIR studies showed that chitosan was absorbed on ceramic particle surface via hydroxyl and amid bonds. In order to evaluate the coating, its structure and electrochemical properties were studied. It was concluded that increasing the process voltage led to an increase in particle size and porosity, but induced cracks in the coating. In the presence of the polymer-bioactive glass coating, current density in artificial saliva was decreased by 52% and corrosion potential shifted toward more noble values.     

三元硼化物陶瓷涂层的制备及其力学性能研究

笔者采用的是在Q235钢基体表面用固相反应法制备三元硼化物陶瓷涂层,因为固相反应法制备陶瓷消耗的能源少、污染小、工艺简单,相对传统的制备工艺所需成本较低,所以研究固相反应型三元硼化物陶瓷涂层有很高的科学价值和实用价值.笔者采用Fe-B、Mo、Fe、Al、Cr为陶瓷骨料,使用无机粘结剂磷酸二氢铝作为陶瓷涂层的粘结剂来制备...     

Electrophoretic deposition of bioactive glass nanopowders on magnesium based alloy for biomedical applications

To slow down the initial biodegradation rate of magnesium (Mg) alloy, crystalline nano-sized bioactive glass coating was used to deposit on micro-arc oxidized AZ91 samples via electrophoretic deposition (EPD). Zeta potential and conductivity of the bioactive glass suspension were characterized at various pH values to identify the most stable dispersion conditions. The bone-bonding properties of bioactive glass coated samples were evaluated in terms of apatite-forming ability during the immersion in simulated body fluid (SBF) solution. Results revealed that the ability to form a bioactive glass coating via EPD was influenced by the degree of its crystalline phase composition. Moreover, the potentiodynamic polarization tests recorded significant drops in corrosion current density and corrosion rate of the coated samples which implies a good level of corrosion protective behavior. These preliminary results show that this process will enable the development of Mg implants in the later stage of bone healing.     

交流阻抗谱研究钙磷陶瓷电沉积层的结构

用交流阻抗技术研究了不同电沉积时间的钙磷陶瓷沉积层。结果表明，沉积时间不同的陶瓷沉积层的交流阻抗谱存在显著的差别。采用双层结构物理模型，对不同沉积时间陶瓷沉积层的交流阻抗谱进行计算机拟合，得到的等效电路各元件拟合值显示：电极表面钙磷陶瓷为内密外疏型梯度沉积层。在陶瓷电沉积过程中，钙磷晶粒同时沉积于距电极表面不同距离的部位，沉积层厚度增加的同时内层密度也在逐渐增加，整个 只层的梯度结构处于动态变化之中。     

Improved corrosion resistance of Al2O3 ceramic coatings on AZ31 magnesium alloy fabricated through cathode plasma electrolytic deposition combined with surface pore-sealing treatment

In this study, we explored the phase compositions and morphologies of the ceramic coatings from different aluminum sources (aluminum isopropoxide, aluminum nitrate, or a mixture of the two) prepared using cathode plasma electrolytic deposition (CPED) onto AZ31 magnesium alloys. Scanning electron microscopy and X-ray diffraction analyses of these coatings indicate that the deposited ceramic made from aluminum isopropoxide was composed of γ-Al₂O₃ whereas the one made from aluminum nitrate was composed of MgA1₂O₄, and that the former was more compact and uniform than the latter. A composite coating was prepared using epoxy resin as a protective layer that sealed the micropores on the CPED coating, thereby further improving its anticorrosion property. The elemental distribution of the cross-section of the composite coating was examined via energy dispersive spectroscopy. Corrosion resistance was investigated using potentiodynamic polarization curves and electrochemical impedance spectroscopy in a 3.5?wt% NaCl medium, and a salt spray test. The results indicate that the corrosion protection property of the Al₂O₃/epoxy resin coating of the magnesium alloy was better than that of the single Al₂O₃ coating. A cross-cut test revealed that the adhesion of the Al₂O₃/epoxy resin composite coating to the magnesium alloy surface was better than that of the single epoxy resin coating. The approach presented herein provides an attractive way to modify the surface of magnesium alloys to improve anticorrosion.     

Q235钢铁/AI-Ni镀层/微弧氧化陶瓷膜的性能研究

在Na2 SiO3溶液中,采用微弧氧化技术将钢铁基体上的A1-Ni合金镀层氧化为陶瓷膜.利用SEM观察Al-Ni陶瓷膜的表面形貌;利用Tafel极化曲线评价了A1-Ni陶瓷膜的耐蚀性;讨论了Na2 SiO3的质量浓度对陶瓷膜性能的影响.结果表明:Na2 SiO3的质量浓度对该陶瓷膜的厚度、硬度、耐蚀性均有一定的影响.     

Electrophoretic deposition of nanostructured TiO2/alginate and TiO2-bioactive glass/alginate composite coatings on stainless steel

Abstract

Two alginate (Alg) based composite coatings on stainless steel AISI 316L substrates, one containing titania nanoparticles (n-TiO₂) and another one a mixture (50/50 wt-%) of n-TiO₂ and bioactive glass (BG), intended for biomedical applications, were developed by electrophoretic deposition (EPD) from ethanol/water suspensions. Different n-TiO₂ (2–10 g L^?1) and BG (1–5 g L^?1) contents were studied for a fixed alginate concentration (2 g L^?1), and the properties of the electrophoretically obtained coatings were characterised. Coatings with high ceramic content (up to 67 vol.-%) were obtained. The presence of BG particles improves the mechanical properties of the coatings by increasing the adhesion to the substrate and also accelerates the formation of hydroxyapatite after immersion of the coatings in simulated body fluid. The electrochemical behaviour of the coated substrates, evaluated by polarisation curves in Dulbecco’s modified eagle medium at 37°C, confirmed the corrosion protection function of the novel EPD coatings. The present polymer–ceramic composite coatings belong to an emerging family of bioactive, compliant coatings that are promising for a range of biomedical applications.