Effects of reformed exhaust gas recirculation on the HC and CO emissions of a spark-ignition engine fueled with LNG

Reformed exhaust gas recirculation (REGR), which can generate onboard hydrogen-rich gas (i.e., the reformate including H₂, CO, unreformed hydrocarbon, etc.) via catalytic reforming of fuel and engine exhaust gas, is an attractive way to improve the performance and emissions characteristics of the engine fueled with liquefied natural gas (i.e., NG engine). However, the leakage during the valve overlap period and incomplete burning of the added reformate may lead to extra HC and CO emissions from the engine with REGR. In the present study, a multi-dimensional computation fluid dynamics model coupled with a detailed chemical kinetic mechanism was developed to investigate the effects of the ratio of reformate addition (R_ref) and exhaust valve closed (EVC) timing on the total emissions characteristics as well as the sources of HC and CO emissions from the engine. The emissions from the combustion and the leaking were included to calculate the total emissions. Moreover, the unburned CO from the added reformate was distinguished from the total CO emissions by adding marked-species. Results show that the unburned CH₄ in the cylinder is the main component of the total CH₄ emissions. Due to the increase of the concentrations of OH, O and H radicals during the combustion process, the oxidization of CH₄ is promoted with the increase of R_ref at high load, and therefore the total CH₄ emissions decrease. However, the total CO emissions increase with the increase of R_ref, and it is demonstrated that the unburned CO from the added reformate increases and turns to be the main sources of the total CO emissions. At R_ref of 10%, the total CH₄ and CO emissions firstly remain nearly constant and then increase dramatically with the delay of EVC timing. Therefore, low concentration of CO in the reformate and short valve duration are recommended to achieve low HC and CO emissions for the NG engine with REGR.     

Hydrogen-rich gas generation via the exhaust gas-fuel reformer for the marine LNG engine

Reformed exhaust gas recirculation technology has attracted great attention in internal combustion engines. A platform of an exhaust gas-fuel reformer connected with the marine LNG engine was set up for generating on-board hydrogen. Based on the platform, effects of the methane to oxygen ratio (M/O) and reformed exhaust gas ratio (R_EG) from the reformer and excess air ratio (λ) from the engine on the components, hydrogen yield, thermal efficiency and reforming process of the reformer were experimentally investigated. Results shown that hydrogen-rich gases (reformate) can be generated by reforming the mixture of engine exhaust gas (about 400 °C) and methane supplied via the reformer with Ni/Al₂O₃ catalyst, and the hydrogen concentration of reformate was between 6.2% and 12.6% by volume. The methane supplied rate and λ affected the components and temperature of the reactant in the reformer, while R_EG changed the gas hour space velocity during the exhaust gas-fuel reforming processes, resulting in the difference in the components of the reformate and thermal efficiency. At the present experimental condition, the highest H₂ concentration reformate was generated under the M/O of 2.0, λ of 1.55 and R_EG of 6%.     

Improving gasoline direct injection (GDI) engine efficiency and emissions with hydrogen from exhaust gas fuel reforming

Exhaust gas fuel reforming has been identified as a thermochemical energy recovery technology with potential to improve gasoline engine efficiency, and thereby reduce CO₂ in addition to other gaseous and particulate matter (PM) emissions. The principle relies on achieving energy recovery from the hot exhaust stream by endothermic catalytic reforming of gasoline and a fraction of the engine exhaust gas. The hydrogen-rich reformate has higher enthalpy than the gasoline fed to the reformer and is recirculated to the intake manifold, i.e. reformed exhaust gas recirculation (REGR).     

Analysis of reformed EGR on the performance of a diesel particulate filter

The use of a diesel particulate filter (DPF) in combination with an upstream diesel oxidation catalyst (DOC) has been successfully implemented and shown to reduce carbon monoxide (CO), hydrocarbon (HC) and Particulate Matter (PM) diesel exhaust gas emissions. However issues including cost, size and uncontrolled active regeneration under a low temperature window still require attention. This study therefore primarily focuses on the potential benefits of using a single catalytic coated DPF (cDPF) and a combined DOC-cDPF instead of the DOC-DPF aftertreatment system utilising a passive, low temperature regeneration method. Comparisons were made through monitoring exhaust gas compositions from an experimental single cylinder diesel engine as well as measuring the pressure drop across the filters to analyse the accumulation of soot particles. The influence of reformed EGR (REGR), enriched simulated hydrogen (H₂) and CO, on DPF and cDPF soot loading was of interest as H₂ promotes the NO to NO₂ oxidation. Similarly the addition of simulated reformate (added either directly into the engine intake or exhaust manifold) for optimal performance of the aftertreatment systems was examined.The effects of adding REGR resulted in a significant decrease in total engine-out NO_x emissions, as well as an increase in both NO₂ concentration and NO₂/NO_x ratio. This resulted in improved filter efficiency and overall loading, especially under a DOC-cDPF aftertreatment configuration system. As a whole, a simultaneous NO_x and PM reduction was achieved.     

On-board generation of hydrogen to improve in-cylinder combustion and after-treatment efficiency and emissions performance of a hybrid hydrogen–gasoline engine

Hydrogen on-board fuel reforming has been identified as a waste energy recovery technology with potential to improve Internal combustion engines (ICE) efficiency. Additionally, can help to reduce CO₂, NO_x and particulate matter (PM) emissions. As this thermochemical energy is recovered from the hot exhaust stream and used in an efficient way by endothermic catalytic reforming of petrol mixed with a fraction of the engine exhaust gas. The hydrogen-rich reformate has higher enthalpy than the petrol fed to the reformer and is recirculated to the intake manifold, which will be called reformed exhaust gas recirculation (rEGR).The rEGR system has been simulated by supplying hydrogen (H₂) and carbon monoxide (CO) into a conventional Exhaust Gas Recirculation (EGR) system. The hydrogen and CO concentrations in the rEGR stream were selected to be achievable in practice at typical gasoline exhaust temperatures (temperatures between 300 and 600 °C). A special attention has been paid on comparing rEGR to the baseline ICE, and to conventional EGR. The results demonstrate the potential of rEGR to simultaneously increase thermal efficiency, reduce gaseous emissions and decrease PM formation.Complete fuel reformation can increase the calorific value of the fuel by 28%. This energy can be provided by the waste heat in the exhaust and so it is ideal for combination with a gasoline engine with its high engine-out exhaust temperatures.The aim of this work is to demonstrate that exhaust gas fuel reforming on an engine is possible and is commercially viable. Also, this paper demonstrates how the combustion of reformate in a direct injection gasoline engine via reformed Exhaust Gas Recirculation (rEGR) can be beneficial to engine performance and emissions.     

Effect of exhaust gas recirculation (EGR) temperature for various EGR rates on heavy duty DI diesel engine performance and emissions

DI diesel engines are well established today as the main powertrain solution for trucks and other relevant heavy duty vehicles. At the same time emission legislation (mainly for NO_x and particulate matter) becomes stricter, reducing their limit to extremely low values. One efficient method to control NO_x in order to achieve future emissions limits is the use of rather high exhaust gas recirculation (EGR) rates accompanied by increased boost pressure to avoid the negative impact on soot emissions. The method is based on the reduction of gas temperature level and O₂ availability inside the combustion chamber, but unfortunately it has usually an adverse effect on soot emissions and brake specific fuel consumption (bsfc). The use of high EGR rates creates the need for EGR gas cooling in order to minimize its negative impact on soot emissions especially at high engine load were the EGR flow rate and exhaust temperature are high. For this reason in the present paper it is examined, using a multi-zone combustion model, the effect of cooled EGR gas temperature level for various EGR percentages on performance and emissions of a turbocharged DI heavy duty diesel engine operating at full load. Results reveal that the decrease of EGR gas temperature has a positive effect on bsfc, soot (lower values) while it has only a small positive effect on NO. As revealed, the effect of low EGR temperature is stronger at high EGR rates.     

Comparison of the effects of EGR and lean burn on an SI engine fueled by hydrogen-enriched low calorific gas

A naturally aspirated spark ignition (SI) engine fueled by hydrogen-blended low calorific gas (LCG) was tested in both exhaust gas recirculation (EGR) and lean burn modes. The “dilution ratio” was introduced to compare their effects on engine performance and emissions under identical levels of dilution. LCG composed of 40% natural gas and 60% nitrogen was used as a main fuel, and hydrogen was blended with the LCG in volumes ranging from 0 to 20%. The engine test results demonstrated that EGR operations at stoichiometry showed a narrower dilution range, inferior combustion characteristics, lower brake thermal efficiency, faster nitrogen oxides (NO_x) suppression, and higher total hydrocarbon (THC) emissions for all hydrogen blending rates compared to lean burn. These trends were mainly due to the increased oxygen deficiency as a result of using EGR in LCG/air mixtures. Hydrogen enrichment of the LCG improved combustion stability and reduced THC emissions while increasing NO_x. In terms of efficiency, hydrogen addition induced a competition between combustion enhancement and increases in the cooling loss, so that the peak thermal efficiency occurred at 10% H₂ with excess air ratio of 1.5. The engine test results also indicated that a close-to-linear NO_x-efficiency relationship occurred for all hydrogen blending rates in both operations as long as stable combustion was achieved. NO_x versus combustion duration analysis showed that adding H₂ reduced combustion duration while maintaining the same level of NO_x. The methane fraction contained in the THC emissions decreased slightly with an increase in hydrogen enrichment at low EGR or excess air dilution ratios, but this tendency was diminished at higher dilution ratios because of the combined dilution effects from the inert gas in the LCG and the diluents (EGR or excess air).     

Numerical study of effects of reformed exhaust gas recirculation (REGR) on dimethyl ether HCCI combustion

The effects of reformed exhaust gas recirculation (REGR) on combustion and emissions of dimethyl ether (DME) homogeneous charge compression ignition (HCCI) engines are studied by multi-dimensional CFD coupled with chemical kinetic model. The results show that REGR combing EGR and DME reformed gases (DRG) improves combustion and emissions. REGR can delay ignition time by both EGR and DRG, and makes main combustion closer to top dead center (TDC), which is beneficial to reducing compression negative work and broadening load range of HCCI engines. The interaction of DRG and EGR helps avoid too high pressure rise rate or low power performance when being applied independent of each other. HC, CO and NO_x emissions can be controlled simultaneously by REGR. Both advantages of DRG and EGR are used to decrease the emissions of HCCI engines by REGR, while the disadvantages of high emissions are alleviated when one of them is applied.     

Hydrogen rich exhaust gas recirculation (H2EGR) for performance improvement and emissions reduction of a compression ignition engine

Hydrogen (H₂), being carbon free energy carrier, is best suitable for compression ignition (CI) engines with better performance and lower carbon derived emissions. Novelty of present study is the employment of low-cost catalyst (alumina) for production of H₂ reformate (hydrogen rich exhaust gas recirculation: H2EGR) in an indigenous catalytic reactor. Experimental tests were carried out on a CI engine under three conditions; base diesel, exhaust gas recirculation (EGR), and H2EGR. Results indicated that brake thermal efficiency of the engine with H2EGR was higher than EGR and comparable with base diesel operation. All carbon-based emissions including smoke emission decreased significantly with H2EGR than diesel and EGR operations. In addition, oxides of nitrogen emission (NO_x) also decreased by about 46% with H2EGR than base diesel operation. It is concluded that H2EGR is a promising option for CI engines for simultaneous reduction of both NO_x and smoke emissions along with the additional benefit of higher efficiency.     

Experimental study of hydrogen enriched compressed natural gas (HCNG) engine and application of support vector machine (SVM) on prediction of engine performance at specific condition

The effect of excess air ratio (λ) and ignition advance angle (θ_ig) on the combustion and emission characteristics of hydrogen enriched compressed natural gas (HCNG) on a 6-cylinder compressed natural gas (CNG) engine has been experimental studied in an engine test bench, aiming at enriching the sophisticated calibration of HCNG fueled engine and increasing the prediction accuracy of the SVM method on automobile engines. Three different fuel blends were selected for the experiment: 0%, 20% and 40% volumetric hydrogen blend ratios. It is noted that combustion intensity varies with the excess air ratio and the ignition advance angle, so are the emissions. The optimal value of λ or θ_ig has been explored in the specific engine condition. Results show that blending hydrogen can enhance and advance the combustion and stability of CNG engine, and it also has some benefic influence on the emissions such as reducing the CO and CH₄. Meanwhile, a simulation research on forecasting the engine performance by using the support vector machine (SVM) method was conducted in detail. The torque, brake specific fuel consumption and NO_x emission have been selected to characterize the power, economic and emissions of the engine with various HCNG fuels, respectively. It can be seen that the optimal model built by the SVM method can highly describe the relationship of the engine properties and condition parameters, since the value of the complex correlation coefficient is larger than 0.97. Secondly, the prediction performance of the optimal model for torque or BSFC is much better than the case of NO_x. Besides, the optimal model built by the PSO optimization method has the best prediction accuracy, and the accuracy of the model obtained based on the training group with 20% hydrogen blend ratio is the best compared with those of others. The upshots in this article provide experimental support and theoretical basis for the adoption of HCNG fuel on internal combustion engines as well as the application of intelligent algorithmic in the engine calibration technology field.     

Experimental investigation on NG dual fuel engine improvement by hydrogen enrichment

The crude oil graduate depletion, as well as aspects related to environmental pollution and global warming instigated many researches concerning alternative fuels. Natural gas (NG) is one of the most attractive available fuels. A promising technique for its use in internal combustion engines is the dual fuel concept. One of the main problems with this technique is that, at low loads, the engine efficiency decreases compared to conventional diesel. The unburned hydrocarbons and carbon monoxide emissions are also higher in dual fuel mode. An effective method to compensate the demerits of limited lean-burn ability and slow burning velocity of NG is to mix it with a fuel that possesses wide flammability limit and fast burning velocity. Hydrogen (H₂) is thought to be the best gaseous candidate for natural gas.In the present work, NG enrichment with various H₂ blends is investigated as a technique for improving dual fuel mode, especially at low loads. Impact on engine performance and emissions is experimentally examined. Total BSFC is considerably reduced. An important benefit in terms of BTE, reaching to increase a 12% with the 10%H₂ blend compared to the pure NG case, is also achieved. THC and CO emissions are in general reduced as a result of the improvement of gaseous fuel utilization. CO₂ emissions are also in general reduced. Even though a slight increase is in overall observed for NO_x emissions, it's almost insignificant.     

Application of exhaust gas fuel reforming in diesel and homogeneous charge compression ignition (HCCI) engines fuelled with biofuels

This paper documents the application of exhaust gas fuel reforming of two alternative fuels, biodiesel and bioethanol, in internal combustion engines. The exhaust gas fuel reforming process is a method of on-board production of hydrogen-rich gas by catalytic reaction of fuel and engine exhaust gas. The benefits of exhaust gas fuel reforming have been demonstrated by adding simulated reformed gas to a diesel engine fuelled by a mixture of 50% ultra low sulphur diesel (ULSD) and 50% rapeseed methyl ester (RME) as well as to a homogeneous charge compression ignition (HCCI) engine fuelled by bioethanol. In the case of the biodiesel fuelled engine, a reduction of NO_x emissions was achieved without considerable smoke increase. In the case of the bioethanol fuelled HCCI engine, the engine tolerance to exhaust gas recirculation (EGR) was extended and hence the typically high pressure rise rates of HCCI engines, associated with intense combustion noise, were reduced.     

Emissions reductions using hydrogen from plasmatron fuel converters

Improvements in internal combustion engine and aftertreatment technologies are needed to meet future environmental quality goals. Systems using recently developed compact plasmatron fuel converters in conjunction with state-of-the-art engines and aftertreatment catalysts could provide new opportunities for obtaining substantial emissions reductions. Plasmatron fuel converters provide a rapid response, compact means to transform a wide range of hydrocarbon fuels (including gasoline, natural gas and diesel fuel) into hydrogen-rich gas. Hydrogen-rich gas can be used as an additive to provide NO_x reductions of more than 80% in spark ignition gasoline engine vehicles by enabling very lean operation or heavy exhaust engine recirculation. It may also be employed for cold start hydrocarbon reduction. If certain requirements are met, it may also be possible to achieve higher spark ignition engine efficiencies (e.g., up to 95% of those of diesel engines). These requirements include the attainment of ultra lean, high compression ratio, open throttle operation using only a modest amount of hydrogen addition. For diesel engines, use of compact plasmatron reformers to produce hydrogen-rich gas for the regeneration of NO_x absorber/adsorbers and particulate traps for diesel engine exhaust aftertreatment could provide significant advantages. Recent tests of conversion of diesel fuel to hydrogen-rich gas using a low current plasmatron fuel converter with non-equilibrium plasma features are described.     

Prediction of performance,combustion and emission characteristics of diesel-thermal cracked cashew nut shell liquid blends using artificial neural network

This paper explores the use of artificial neural networks (ANN) to predict performance, combustion and emissions of a single cylinder, four stroke stationary, diesel engine operated by thermal cracked cashew nut shell liquid (TC-CNSL) as the biodiesel blended with diesel. The tests were performed at three different injection timings (21°, 23°, 25°CA bTDC) by changing the thickness of the advance shim. The ANN was used to predict eight different engine-output responses, namely brake thermal efficiency (BTE), brake specific fuel consumption (BSFC), exhaust gas temperature (EGT), carbon monoxide (CO), oxide of nitrogen (NO _x ), hydrocarbon (HC), maximum pressure (P _max) and heat release rate (HRR). Four pertinent engine operating parameters, i.e., injection timing (IT), injection pressure (IP), blend percentage and pecentage load were used as the input parameters for this modeling work. The ANN results show that there is a good correlation between the ANN predicted values and the experimental values for various engine performances, combustion parameters and exhaust emission characteristics. The mean square error value (MSE) is 0.005621 and the regression value of R ² is 0.99316 for training, 0.98812 for validation, 0.9841 for testing while the overall value is 0.99173. Thus the developed ANN model is fairly powerful for predicting the performance, combustion and exhaust emissions of internal combustion engines.     

Generating efficiency and emissions of a spark-ignition gas engine generator fuelled with biogas–hydrogen blends

We investigated the generating efficiency and pollutant emissions of a four-stroke spark-ignition gas engine generator operating on biogas–hydrogen blends of varying excess air ratios and hydrogen concentrations. Experiments were carried out at a constant engine speed of 1200 rpm and a constant electric power output of 10 kW. The experimental results showed that the peak values of generating efficiency, maximum cylinder pressure, and NO_x emissions were elevated at an excess air ratio of around 1.2 as the hydrogen concentration was increased. CO₂ emissions decreased as the excess air ratio and hydrogen concentration increased, due to lean-burn conditions and hydrogen combustion. An efficiency per NO_x emissions ratio (EPN) was defined to consider the relationship between the generating efficiency and NO_x emissions. A maximum EPN value of 0.7502 was obtained with a hydrogen concentration of 15%, for an excess air ratio of 2.0. At this EPN value, the NO_x and CO₂ emissions were 39 ppm and 1678.32 g/kWh, respectively, and the generating efficiency was 29.26%. These results demonstrated that the addition of hydrogen to biogas enabled the effective generation of electricity using a gas engine generator through lean-burn combustion.     

Effect of Exhaust Gas Recirculation (EGR) on performance,emissions, deposits and durability of a constant speed compression ignition engine

To meet stringent vehicular exhaust emission norms worldwide, several exhaust pre-treatment and post-treatment techniques have been employed in modern engines. Exhaust Gas Recirculation (EGR) is a pre-treatment technique, which is being used widely to reduce and control the oxides of nitrogen (NO_x) emission from diesel engines. EGR controls the NO_x because it lowers oxygen concentration and flame temperature of the working fluid in the combustion chamber. However, the use of EGR leads to a trade-off in terms of soot emissions. Higher soot generated by EGR leads to long-term usage problems inside the engines such as higher carbon deposits, lubricating oil degradation and enhanced engine wear. Present experimental study has been carried out to investigate the effect of EGR on soot deposits, and wear of vital engine parts, especially piston rings, apart from performance and emissions in a two cylinder, air cooled, constant speed direct injection diesel engine, which is typically used in agricultural farm machinery and decentralized captive power generation. Such engines are normally not operated with EGR. The experiments were carried out to experimentally evaluate the performance and emissions for different EGR rates of the engine. Emissions of hydrocarbons (HC), NO_x, carbon monoxide (CO), exhaust gas temperature, and smoke opacity of the exhaust gas etc. were measured. Performance parameters such as thermal efficiency, brake specific fuel consumption (BSFC) were calculated. Reduction in NO_x and exhaust gas temperature were observed but emissions of particulate matter (PM), HC, and CO were found to have increased with usage of EGR. The engine was operated for 96 h in normal running conditions and the deposits on vital engine parts were assessed. The engine was again operated for 96 h with EGR and similar observations were recorded. Higher carbon deposits were observed on the engine parts operating with EGR. Higher wear of piston rings was also observed for engine operated with EGR.     

Hydrogen supplemented natural gas effect on a DI diesel engine operating under dual fuel mode with a biodiesel pilot fuel

In order to slow down the continuing environmental deterioration, regulations for pollutant emissions limitations are increasingly rigorous. The development of new alternative fuels for internal combustion engines is a very interesting solution not only to overcome the pollution problem but also because of the petroleum shortage. In this context, the present work investigates the improvement of a DI diesel engine operating at constant speed (1500 rpm) and under dual fuel mode with eucalyptus biodiesel and natural gas (NG) enriched by various H₂ quantities (15, 25 and 30 by v%). The eucalyptus biodiesel quantity injected into the engine cylinder is kept constant, to supply around 10% of the engine nominal power, for all examined engine loads. The engine load is further increased using only the gaseous fuel (NG+H₂), which is introduced with the intake air. The effect of H₂/NG blending ratio on the combustion parameters, performance and pollutant emissions of the engine is investigated and compared with those of pure NG case. An important benefit in terms of brake specific fuel consumption, reaching a decrease of 4–10% with the 25% H₂ blend compared to the pure NG case, is achieved. Concerning the pollutant emissions, NG enrichment with H₂ is an efficient solution to enhance the combustion process and hence reduce carbon monoxide, unburned hydrocarbon and soot emissions at high loads where they are important for pure NG. However for the nitrogen oxide emissions, NG blending with H₂ is attractive only at low and medium loads where their levels are lower than pure NG.     

Comparative engine performance and emission analysis of CNG and gasoline in a retrofitted car engine

A comparative analysis is being performed of the engine performance and exhaust emission on a gasoline and compressed natural gas (CNG) fueled retrofitted spark ignition car engine. A new 1.6 L, 4-cylinder petrol engine was converted to the computer incorporated bi-fuel system which operated with either gasoline or CNG using an electronically controlled solenoid actuated valve mechanism. The engine brake power, brake specific fuel consumption, brake thermal efficiency, exhaust gas temperature and exhaust emissions (unburnt hydrocarbon, carbon mono-oxide, oxygen and carbon dioxides) were measured over a range of speed variations at 50% and 80% throttle positions through a computer based data acquisition and control system. Comparative analysis of the experimental results showed 19.25% and 10.86% reduction in brake power and 15.96% and 14.68% reduction in brake specific fuel consumption (BSFC) at 50% and 80% throttle positions respectively while the engine was fueled with CNG compared to that with the gasoline. Whereas, the retrofitted engine produced 1.6% higher brake thermal efficiency and 24.21% higher exhaust gas temperature at 80% throttle had produced an average of 40.84% higher NO_x emission over the speed range of 1500–5500 rpm at 80% throttle. Other emission contents (unburnt HC, CO, O₂ and CO₂) were significantly lower than those of the gasoline emissions.     

An experimental investigation of incomplete combustion of gaseous fuels of a heavy-duty diesel engine supplemented with hydrogen and natural gas

This paper investigates the emissions of the unburned gaseous fuels of a heavy-duty diesel engine converted to operate under natural gas (NG)-diesel and hydrogen (H₂)-diesel dual fuel combustion mode. The detailed effects of the addition of H₂, NG, engine load, and engine speed on the exhaust emissions of the unburned H₂, methane (CH₄), and carbon monoxide (CO) were experimentally investigated. The combustion efficiencies of CH₄ and H₂ supplemented were also examined and compared.     

A modified diesel engine for natural gas operation: Performance and emission tests

A diesel engine was modified for natural gas operation to optimize performance using gaseous fuel. A variation of combustion ratios (CR) including 9.0:1, 9.5:1, 10.0:1 and 10.5:1 was utilized to evaluate engine performance and emissions from the same engine over the engine speeds between 1000 and 4000 rpm. Tested engine performance parameters include brake torque, brake power, specific fuel consumption (SFC) and brake thermal efficiency. Emissions tests recorded total hydrocarbon (THC), nitrogen oxides (NO_x) and carbon monoxide (CO). The results showed that a CR of 9.5:1 had the highest thermal efficiency and the lowest SFC while a CR of 10:1 showed a high torque at low speed. THC emissions were directly proportional to the CR. NO_x emissions increased with increasing CR and then declined after a CR of 10:1.