共查询到20条相似文献,搜索用时 15 毫秒
1.
2.
Metal salts of mono(hydroxypentyl)phthalate [M(HPP)2, where M is Ca2+, Cd2+, Pb2+, or Zn2+] were synthesized by the reaction of 1,5‐pentane diol, phthalic anhydride, and metal acetate. A new series of metal‐containing polyurethanes containing ionic links in the main chain were synthesized by the reaction of hexamethylene diisocyanate or toluylene 2,4‐diisocyanate with the M(HPP)2 salts. The structures of the monomers and polymers were confirmed with infrared, 1H‐NMR, and 13C‐NMR spectra and elemental analysis. The polymers were also characterized with thermogravimetric analysis, differential scanning calorimetry, and solubility and viscosity measurements. The antibacterial activity of these polyurethanes was investigated with the agar diffusion method. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 1194–1206, 2002 相似文献
3.
Carboxymethyl chitosan sodium (CMCTS) was synthesized by chitosan and chloroacetic acid under an alkali catalyst. Acrylic acid sodium salt and methylacrylic acid sodium salt were grafted onto CMCTS to obtain copolymers with good water solubility. The graft reaction was carried out at 70°C for 2 h, and ammonium persulfate was used as an initiator. The structure changes of chitosan and its derivatives were investigated by the FTIR. The antibacterial activity of chitosan derivatives against Staphylococcus aureus and Escherichia coli were explored by the viable cell counting method. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 1357–1361, 2002 相似文献
4.
根据α,β-不饱和醛酮亲核加成反应原理合成化合物L{[3-(4-N,N-dimethyl-pyenyl)-5-Anthracen-9-yl]-Pyrazoline}和化合物M[3-ferroceny-5-(Anthracen-9-yl)-Pyrazoline]。利用~1H NMR和~(13)C NMR对化合物进行结构表征,通过抑菌实验研究化合物抑菌生物活性。探析新型吡唑啉衍生物对革兰氏阳性菌、革兰氏阴性菌和真菌的抑菌效果,研究其结构变化对活性的影响。结果表明,化合物L和M对典型革兰氏阳性菌和典型革兰氏阴性菌有一定的抑菌效果,对真核细胞型微生物作用不明显。通过比较两者对细菌的作用结果(抑菌圈直径的大小),化合物L的抑菌作用明显强于化合物M,化合物L吡唑啉环连接N、N-二甲基苯环可能增强了抑菌生物活性。 相似文献
5.
先用两步法合成了无O-甲基化 N,N,N-三甲基壳聚糖季铵盐(TMC),再通过相转移催化合成了N,N,N-三甲基O-辛基壳聚糖季铵盐(TMOC),用 FTIR、1H NMR、EA、TG 等方法对产物进行表征,并研究其抗菌性能。结果表明,TMOC在pH值为5.5的抗菌活性优于pH值为7.2的抗菌活性;TMOC对革兰阳性菌S. aureus的抗菌活性比革兰阴性菌E. coli强。在不影响水溶性的前提下,O-烷基化改性能有效提高壳聚糖季铵盐的抗菌活性,并且抗菌活性随着O-烷基化度的提高而提高。研究结果为壳聚糖基抗菌剂的改性和制备提供了依据。 相似文献
6.
报道了配合物GdI3.2CS(NH2)2.10H2O的新合成方法,通过元素分析、X-射线粉末衍射、红外光谱、质谱、差热-热重分析,确定了配合物的组成和结构,首次测定了配体碘化钆、硫脲和配合物对枯草芽孢杆菌、葡萄球菌和大肠杆菌的抗菌活性。抗菌活性测试结果表明,所有试样对枯草芽孢杆菌的杀死作用显著,且高浓度溶液(0.05 mol/L)比低浓度溶液(0.01 mol/L)的抗菌效果好;对金黄色葡萄球菌、大肠杆菌的杀死作用不明显;浓度为0.05 mol/L时,配合物GdI3.2CS(NH2)2.10H2O对枯草芽孢杆菌的杀死作用大于CS(NH2)2和GdI3.9H2O。 相似文献
7.
以2,4-二氯-5-氟苯乙酮为起始原料,通过β-酮酸酯化,与原甲酸三乙酯缩合,同2-氨基吡啶发生取代,再经环合反应、硼配合反应和哌嗪化反应合成得到了N-吡啶取代喹诺酮抗菌化合物,总收率为39.3%,并对其抗菌活性进行了试验。 相似文献
8.
利用二茂铁甲醛分别与1,2-乙二胺、1,3-丙二胺和1,4-丁二胺缩合,合成了3种双二茂铁基希夫碱,进行了生物活性实验。结果表明,3种双二茂铁基希夫碱对大肠埃希氏菌和金黄色葡萄球菌均具有较好的抗菌活性,1,3-丙二胺双缩二茂铁甲醛对金黄色葡萄球菌的抑菌能力最强,生物效价为210 U/mg(与四环素盐酸盐相比较);1,4-丁二胺双缩二茂铁甲醛对大肠埃希氏菌的抑菌能力最好,生物效价为1 058 U/mg(与四环素盐酸盐相比较)。3种双二茂铁基希夫碱对大肠埃希氏菌的抑菌能力比对金黄色葡萄球菌的抑菌能力强。 相似文献
9.
A large number of copolymers have been prepared from cardanyl acrylate on suspension polymerisation with vinyl monomers like methyl acrylate, ethyl acrylate, butyl acrylate, etc. These copolymer beads are almost uniform in size. Infrared spectral and swelling behaviour studies explain their various characteristics. The thermal behaviour of the copolymer beads has been studied with the help of a new computer method known as the LOTUS package method. 相似文献
10.
11.
稀土-蛋氨酸-邻菲咯啉配合物的合成、表征及抗菌活性研究 总被引:3,自引:1,他引:2
采用冷凝回流法合成了4种新型稀土(镧、铕、钐和钕)-蛋氨酸-邻菲咯啉三元配合物,通过元素分析、EDTA-滴定、摩尔电导、红外光谱,确定了配合物的组成为RE(Met)_3phenCl_3·3H_2O(RE:La~(3+)、Eu~(3+)、Sm~(3+)、Nd~(3+);Met=L-蛋氨酸;phen=邻菲咯啉).抗菌活性的研究表明,与配体相比,稀土三元配合物对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)均具有更强的抑菌能力. 相似文献
12.
13.
14.
15.
16.
以1-金刚烷甲酸为原料,通过酯化、肼解制得1-金刚烷甲酰肼,1-金刚烷甲酰肼再与芳香醛反应得到相应的酰腙,最后以苯和DMF为溶剂,酰腙与巯基乙酸脱水环化成2-芳基-3-(1-金刚烷甲酰胺基)-4-噻唑啉酮类化合物,并利用IR、1HNMR、13CNMR、ESI-MS和元素分析对7个目标化合物的结构进行了表征。用MTT方法评价了它们在体外对HepG-2,A549-1和231-2 3种癌细胞株的体外生长抑制活性。结果表明,所合成的7个新化合物均具有潜在的体外抑制癌细胞生长活性。 相似文献
17.
18.
Cationic nanopolystyrenes (CNPSs) were prepared by the polymerization of styrene with a cationic polymerizable emulsifier, N-(2-(methacryloyloxy)ethyl)-N,N-dimethyltetradecane-1-ammonium bromide (MDTB), in the presence of 2,2′-azobis(2-methylpropionamidine) dihydrochloride (APPH). The polymerization kinetics was investigated through monomer conversion versus polymerization time. 1H NMR spectra and FTIR spectra were used to confirm the structures of MDTB and nanopolymers. The particle size, ζ-potential, molecular weight, and thermal stability were also investigated by Zetasizer, gel permeation chromatography, and thermogravimetric analysis, respectively. The antibacterial activities of the obtained products were evaluated by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Staphylococcus aureus ATCC 29913 (S. aureus, a Gram-positive bacterium) and Escherichia coli ATCC 25922 (E. coli, a Gram-negative bacterium). The results indicated that the polymerization has the characteristics of microemulsion polymerization, all nanopolystyrenes are cationic and can be stored in the form of a microemulsion in aqueous phase, CNPSs present stable chemical structure at 190 °C, and their MIC and MBC reach 0.0625 and 0.125 mg mL−1 for E. coli, 0.0325 and 0.0625 mg mL−1 for S. aureus, respectively. Therefore, CNPSs are a promising new type of polymer antimicrobial agent, which can be used in the development of antimicrobial polymer materials and their products. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48405. 相似文献
19.
R. Puyenbroek P. J. Werkman B. A. C. Rousseeuw E. W. J. M. Drift J. C. Grampel 《Journal of Inorganic and Organometallic Polymers》1994,4(3):289-299
Poly(4-t-butoxycarbonyloxystyrene)-g-poly(dimethylsiloxane) and poly(t-butylmethacrylate)-g-poly(dimethylsiloxane) with various chemical compositions were synthesized via free radical polymerization of 4-t-butoxycarbonyloxystyrene (TBCS) or t-butylmethacrylate (TBMA) with silicone macromers. These macromers were prepared by anionic ring-opening polymerization of hexamethylcyclotrisiloxane (D3) and subsequent termination with a chlorosilane compound having a methacrylate functionality. The morphology of the graft copolymer systems was investigated by DSC and TEM. 相似文献
20.
Bernard Boutevin Yves Hervaud Ahmed Boulahna El Mestafa El Hadrami 《Polymer International》2002,51(5):450-457
We report, for the first time, the synthesis of a phosphonated styrenic monomer dimethyl vinylbenzyl phosphonate (VBP) according to the methods described in the literature for its equivalent diethyl vinylbenzyl phosphonate, and also the monodealkylation of this monomer (VBP) to the monosalt in a neutral medium and to the corresponding monoacid via a sulfonic resin. Various statistical copolymers and statistical block copolymers of styrene and VBP were prepared with different molar percentages of these comonomers. The dealkylation of statistical copolymers was carried out in the same way as for VBP. The phosphonated statistical copolymers, prepared, were characterized by various analytical methods which show good agreement with their structures. © 2002 Society of Chemical Industry 相似文献