共查询到20条相似文献,搜索用时 8 毫秒
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Takahashi M Saibara T Nemoto Y Ono M Akisawa N Iwasaki S Toda K Ogawa Y Wakatsuki A Inagaki S Onishi S 《Lipids》2003,38(7):687-692
The unique inborn hypertriglyceridemia seen in FLS (fatty liver Shionogi) mice was relieved by the administration of purified
apolipoprotein (apo) C-II. Lipoprotein lipase (LPL) and its cofactor, apoC-II, play a pivotal role in VLDL metabolism. Therefore,
we investigated the genetic background involved in this hypertriglyceridemia. Plasma levels of TG and total cholesterol as
well as LPL activity were measured in male FLS mice and C57/BL6J mice. Agarose gel electrophoresis and fast protein liquid
chromatography were used to analyze the lipoprotein profile. A cross experiment was done to determine the genetic background
of hypertriglyceridemia observed in FLS mice. cDNA sequences of apoC-II and apoC-III of FLS mice were determined. Preα-lipoprotein
was the predominant lipoprotein class in FLS mouse plasma. LPL activity remained in the range observed in C57/BL6J mice, and
purified apoC-II transiently relieved FLS mice from hypertriglyceridemia. Preα-lipoproteinemia was inherited in an autosomal
recessive manner. ApoC-III appeared to be a causal factor for this unique hypertriglyceridemia. Microsatellite analysis, however,
revealed that the responsible chromosome was not 7; rather, apoC-III mapped onto chromosome 9. Therefore, we suggest apoC-III
as a candidate causative factor for the hypertriglyceridemia observed in FLS mice because an excessive amount of apoC-III
attenuates LPL activity in vivo and in vitro. 相似文献
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Measurement technique on the diffusion coefficient of powder flow in a screw feeder by X-ray visualization 总被引:3,自引:0,他引:3
Measuring the diffusion coefficient of powder flow, which shows the magnitude of mixing, using X-ray visualization has been developed with the help of image processing techniques. Injecting minute metallic tracers into the powder yielded flow characteristics using the X-ray penetration images. The diffusion coefficient of the flow was determined by tracer figure deformation with time. Using this method, we evaluated four kinds of powder flows transported using different shaped screws in a screw feeder unit. The following results were obtained from this investigation: (i) Increasing the pitch width of the screw yielded decreased transport velocity and a larger diffusion coefficient. (ii) Double screw provided the largest transport velocity and the smallest diffusion coefficient.In addition, uncertainty analysis was applied to the method of measuring the diffusion coefficient to achieve greater bias limit. 相似文献
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我公司生料配料取料采用CGQ150/22.5侧式刮板取料机,在取料机行进过程中,为保证大车行走前后轮水平同步,在两个主驱动轮内侧,分别设置了两对防偏轮,固定在轨道两侧.在使用中经常出现因防偏轮轴承损坏,使大车行走前后轮发生歪斜,导致取料机行进过程中跳停,必须在回车后,将前后轮重新调正后,才能再次取料.致使取料时间延长,... 相似文献
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Bahaa M. Abu-Zied 《Ceramics International》2019,45(4):4540-4548
This article focuses on the nano-crystalline tricobalt tetraoxide (Co3O4) synthesis using the combustion method. The fabrication process involves the combustion a mixture of cobalt nitrate as oxidized and expanded polystyrene (EPS) as a novel fuel. The effects of fuel/oxidizer ratio on the phases formed, Co3O4 as a major phase and CoO as an impurity, and the Co3O4 crystallite size have been addressed. Based on the thermal analyses data (TGA and DTA), which follow the phase changes during the heat treatment of the parent fuel/oxidizer precursor, the different parent precursors have been calcined at 500?°C. Characterization of the formed solids has been performed using various tools (XRD, FT-IR, SEM, TEM, and XPS). It was concluded that the EPS content, in the combustion precursor mixtures, is a key parameter that controls the phase features of the prepared nanomaterials. CoO impurity was detected for the solids with EPS?>?4?wt%. The crystallite size, morphology, and the surface elemental concentration are influenced by changing the EPS content. The activity of the different powders towards hydrogen peroxide decomposition has been evaluated at the 35–50?°C temperature range. 相似文献