卷烟逐口烟丝消耗量的测定

为准确测定卷烟抽吸时的逐口烟丝消耗量,基于力矩平衡原理设计了一种能实时监测卷烟抽吸过程中烟支质量损失的装置,结合抽吸比率实验获得了卷烟抽吸时的逐口烟丝消耗量,并进一步考察了滤嘴通风率对逐口烟丝消耗量的影响,探讨了燃烧锥端进气量与烟丝消耗量之间的关系。结果表明：1）设计装置能准确测定出烟支的质量变化,且精密度RSD<1%;2）由卷烟抽吸失重曲线可明显区分出烟支阴燃和吸燃过程,并根据卷烟吸燃前后质量差计算得到了卷烟抽吸逐口质量损失,其大小随抽吸口序的增加而增加;3）结合抽吸比率实验测得了卷烟抽吸逐口烟丝消耗量,实验所用1#、2#和3#卷烟稳定抽吸时其逐口烟丝消耗量在19.9～26.2 mg之间;4）相同口序下卷烟抽吸消耗的烟丝量随滤嘴通风率增大而减小;5）燃烧锥端进气量与烟丝消耗量呈线性关系,且每毫升燃烧锥端进气量消耗的烟丝量与烟丝燃烧性相关。     

Revising the machine smoking regime for cigarette emissions: implications for tobacco control policy

Background

The WHO Framework Convenion on Tobacco Control includes provisions for testing and regulating cigarette emissions. However, the current international standard for generating cigarette emissions—the ISO machine smoking regime—is widely acknowledged to be inappropriate for purposes of setting regulatory restrictions.

Objective

To review alternatives to the ISO machine smoking regime and the extent to which they: 1) Represent human smoking behaviour, 2) Reduce the potential for industry exploitation, particularly in the area of risk communication, and 3) Serve as suitable measures for product regulation.

Methods

Emissions data from 238 Canadian cigarette brands tested under the ISO and “Canadian Intense” machine smoking regimes.

Results

None of the alternative smoking regimes, including the Canadian Intense method, are more “representative” of human smoking behaviour and none provide better predictors of human exposure.

Conclusions

Given that alternatives such as the Canadian Intense regime are subject to the same fundamental limitations as the ISO regime, key questions need to be addressed before any smoking regime should be used to set regulatory limits on smoke emissions. In the meantime, regulators should remove quantitative emission values from cigarette packages and more work should be done on alternative machine smoking methods.The issue of how to test and regulate conventional cigarettes represents a critical challenge for tobacco control. To date, the primary means of testing cigarette toxicity has been to machine smoke the cigarettes according to a standard puffing regime and to measure the chemical emissions in the mainstream smoke. In many jurisdictions, these cigarette “yields” are printed on packages and represent the only source of information on constituents or toxicity available to consumers. Cigarette emissions also serve as a regulatory standard in several of jurisdictions, including the European Union, where brands that generate emissions >10 mg of tar, 1 mg of nicotine or 10 ppm of carbon monoxide are prohibited. The puffing regime used to machine smoke the cigarettes—the International Organization for Standardization (ISO) regime¹—is widely recognised to be inadequate for the purposes of product regulation or consumer information. The ISO regime constitutes a set of puffing parameters that systematically underestimate smoking behaviour in humans.^2,3,4 Tobacco manufacturers have also designed cigarette brands to perform one way under the machine smoking conditions, but to deliver much greater smoke constituents to humans.^5,6 As a result, the emissions generated under the ISO smoking regime have little relationship with actual measures of human exposure, and exaggerate the differences between brands in a manner that has proved deceptive to both consumers and regulators.^7,8,9 Overall, the emissions from the ISO regime have served as more of an industry marketing tool to falsely reassure health‐concerned smokers, rather than as a valid measure of cigarette toxicity.^2,10,11,12There is a growing movement to develop a more meaningful machine testing method. The World Health Organization''s Framework Convention on Tobacco Control (FCTC)—the world''s first international public health treaty—includes provisions for testing and regulating cigarette emissions under Article 9.¹³ These provisions will need to be specified now that the FCTC has come into force. After discussions with the WHO, the ISO convened a working group (ISO TC 126 WG9) to develop recommendations for “…a robust and practical smoking regime that as far as possible is representative of smokers'' behaviour”. Meanwhile, the World Health Organization''s Study Group on Tobacco Product Regulations (WHO TobReg) has developed its own set of recommendations, which were under consideration by the ISO Working Group.¹⁴ There are also concerns that the ISO committee structure responsible for setting tobacco standards is dominated by the tobacco industry.¹²Before any new testing regime is implemented, it is critical to ensure that the new standards will serve the interests of public health rather than the tobacco industry. The purpose of this paper is to review the smoking regimes that are under consideration by the ISO Working Group, and to examine the implications for tobacco control policy and product regulation. In particular, we examine the extent to which the proposed regimes will: (1) succeed in “representing” smoking behaviour in humans and generate better predictors of human exposure; (2) reduce the potential for industry exploitation, particularly in the field of risk communication; and (3) help to establish more effective regulatory limits on cigarette toxicity.     

Correlates of cigarette smoking during pregnancy and its genetic and environmental overlap with nicotine dependence.

Cigarette smoking during pregnancy (CSDP) is associated with a number of negative outcomes in the offspring. Therefore, clarifying the correlates of CSDP and the extent to which CSDP is associated with nicotine dependence is an important step toward reducing its rate in the general population. Using data from 1,134 adult Australian female monozygotic and dizygotic twin pairs, we explored the associations between CSDP and sociodemographic and psychiatric correlates and between CSDP and patterns of cigarette smoking. Further, we examined the role of heritable and environmental influences on CSDP and investigated whether these latent risk factors are shared with a predisposition to nicotine dependence. Women smoking during an entire pregnancy reported heavier dependence and more unsuccessful quit attempts, compared with the community sample of mothers and with women who smoked during only part of a pregnancy. Educational attainment, weekly church attendance, spousal current smoking, and nicotine dependence also were associated with CSDP. Heritable influences explained 34% of the variation in CSDP, with the remainder related to nonshared environmental factors. A large proportion of the genetic influences on CSDP were shared with DSM-III-R nicotine dependence, with little overlap across the nonshared environmental influences. A lifetime history of difficulty with smoking cessation, in conjunction with social background and psychiatric comorbidity, especially during pregnancy, needs to be considered by treatment providers when counseling expectant mothers about the potential risks of CSDP.     

Telephone assistance for smoking cessation: one year cost effectiveness estimations

A randomised trial evaluated the American Cancer Society's telephone counselling service to assist smoking cessation. Counselling nearly doubles a smokers' odds of quitting and maintaining cessation for one year. The estimated cost for each case of maintained smoking cessation attributable to counselling availability is approximately 1300 dollars.     

Use of smokeless tobacco is a risk factor for cigarette smoking.

This study assessed the risk of smoking uptake over 2 years in adolescent boys (in grades 7 and 9) who had used smokeless tobacco (ST). We used logistic regression to determine whether the odds of adolescent boys taking up regular smoking over a period of 2 years were greater among initial nonsmokers who used ST, compared with nonusers of ST, after accounting for six well-established predictors of smoking. Initiation of weekly smoking 2 years after baseline was associated with ST use at baseline, even after including dichotomous measures of parent, sibling, or close friend smoking; low academic grades; 30-day alcohol use; and a scale measure of deviant behavior. With these other predictors included in the model, the odds ratio for the association of ST use with weekly smoking after 2 years was strong and significant (OR = 2.55, 95% CI 1.45-4.47, p<.001). The use of ST in the 7th and 9th grades is a significant risk factor for subsequent smoking even when controlling for other factors.     

A pilot study on voucher-based incentives to promote abstinence from cigarette smoking during pregnancy and postpartum.

We report results from a pilot study examining the use of vouchers redeemable for retail items as incentives for smoking cessation during pregnancy and postpartum. Of 100 study-eligible women who were still smoking upon entering prenatal care, 58 were recruited from university-based and community obstetric practices to participate in a smoking cessation study. Participants were assigned to either contingent or noncontingent voucher conditions. Vouchers were available during pregnancy and for 12 weeks postpartum. In the contingent condition, vouchers were earned for biochemically verified smoking abstinence. In the noncontingent condition, vouchers were earned independent of smoking status. Abstinence monitoring and associated voucher delivery was conducted daily during the initial 5 days of the cessation effort, gradually decreased to every other week antepartum, increased to once weekly during the initial 4 weeks postpartum, and then decreased again to every other week for the remaining 8 weeks of the postpartum intervention period. Contingent vouchers increased 7-day point-prevalence abstinence at the end-of-pregnancy (37% vs. 9%) and 12-week postpartum (33% vs. 0%) assessments. That effect was sustained through the 24-week postpartum assessment (27% vs. 0%), which was 12 weeks after discontinuation of the voucher program. Total mean voucher earnings across antepartum and postpartum were 397 US dollars (SD=414 US dollars) and 313 US dollars (SD=142 dollars) in the contingent and noncontingent conditions, respectively. The magnitude of these treatment effects exceed levels typically observed with pregnant and recently postpartum smokers, and the maintenance of effects through 24 weeks postpartum extends the duration beyond those reported previously.     

Exposure to cigarette promotions and smoking uptake in adolescents: evidence of a dose-response relation

OBJECTIVE: To assess whether a dose-response relation exists between the number of cigarette promotional items (CPIs) owned by an adolescent, and smoking behaviour. DESIGN AND SETTING: Voluntary, self administered survey of 1265 sixth through to 12th grade students (ages 10-19 years), representing 79-95% of all students attending five rural New Hampshire and Vermont public (state funded) schools in October 1996. The association between the number of CPIs owned by students and smoking behaviour was examined using multivariate regression methods. OUTCOME MEASURES: Adjusted odds of being a smoker (>/= 100 cigarettes lifetime) and, among never and experimental smokers, adjusted cumulative odds of having higher levels on a smoking uptake index given the number of CPIs owned. RESULTS: One third of students owned a CPI (n = 406). Among owners, 211 owned one, 82 owned two, 57 owned three, 24 owned four, 23 owned five, and 7 students owned six CPIs. The number of CPIs owned by students was not associated with grade in school but was significantly higher in males, those with poorer school performance, those who perceived high prevalence of peer smoking, and those with higher exposure to peer and family smoking. The more items a student owned, the greater the chances of being a smoker. For example, smoking prevalence was 11.2% for those not owning a CPI, 41.5% for those owning two, 58.5% for those owning four, and 71.4% for those owning six CPIs. The dose-response relation remained after controlling for confounding; compared with those who did not own a CPI, the likelihood of being a smoker was significantly higher for those who owned one CPI, with an adjusted odds ratio (OR) of 2.7 (95% confidence interval (CI) 1.7 to 4.1); OR was 3.4 (95% CI 1.9 to 5.9) for those owning two CPIs, and 8.4 (95% CI 5.0 to 14.2) for those owning three or more CPIs. After excluding smokers, there was a crude dose-response association between CPI ownership and higher rates of experimentation with cigarettes among sixth to ninth graders (ages 11-15 years) only (n = 543). After controlling for confounding influences, the dose-response relation remained, with the likelihood of being higher on the smoking uptake index rising with the number of CPIs owned: one CPI, adjusted cumulative OR 1.7 (95% CI 1.1 to 2.60); two CPIs, OR 2.5 (95% CI 1.2 to 5.1); and three or more CPIs, OR 4.8 (95% CI 1.9 to 12.2). CONCLUSIONS: This study offers evidence of a dose-response relation between the number of CPIs owned by adolescents and higher likelihood of experimental and established smoking. The dose-response relation persists after controlling for confounding influences. These data provide further support of a causal relation between tobacco promotional campaigns and smoking behaviour among adolescents.     

What parents prefer and children like – Investigating choice of vegetable-based food for children

The inherent challenge of investigating food choice of new products for children is that more than one person is involved in the long-term decision-making. Parents decide in the purchase situation while children pass their verdict when they consume the meal. In this paper we suggest linking family decision-making and food choice, and reveal results from two empirical studies of vegetable-based food for children. One study discloses parents’ preferences regarding different food concepts while the other looks into children’s liking before and after tasting the products. Results show that parents know fairly well what children like. Sharing the meal experience with their children and having meal variation options are important benefits for parents. Parents are more concerned about health while children prefer products that look familiar. However, after tasting an unfamiliar product children are less reserved.     

Smoke constituent exposure and smoking topography of adolescent daily cigarette smokers.

Adolescent smoking prevalence is a major health concern, with 24.4% reporting smoking in the past 30 days and 15.8% considered daily smokers. The purpose of this study was to characterize biobehavioral nicotine dependence, smoke constituent exposure and smoking topography in adolescent daily smokers. Relationships among biological markers of nicotine dependence (nicotine boost, carbon monoxide [CO] boost and cotinine levels) with existing self-report measures (modified Fagerstr?m Tolerance Questionnaire [mFTQ] and the motivations for smoking scale) were examined. Gender differences were characterized. Fifty adolescents 13-18 years old were recruited for the study, 50% female. CO, plasma nicotine levels pre- and postcigarette, cotinine, and smoking topography were measured during a smoking bout with participant's usual cigarette. Average CO boost, pre- to postcigarette was 7.2 + 3.6 ppm, baseline cotinine level averaged 224.0 +/- 169.6 ng/ml and nicotine boost averaged 23.4 +/- 21.7 ng/ml. Mean puffs per cigarette was 14.2 +/- 6.3. Males had significantly higher total puff volumes, but similar smoke constituent exposure to females, and higher handling of cigarettes as smoking motive. In regression analysis, 35% of variance in tobacco use, as indicated by baseline cotinine concentration, was explained by maximum puff duration, postcigarette CO level, and nicotine dependence, as measured by the mFTQ. Results indicated adolescents had considerable smoke constituent exposure and nicotine dependence suggesting the importance of appropriate smoking cessation treatment.     

Analysis of hydrogen peroxide in cigarette smoke from selected Chinese cigarette brands under conventional and intense machine smoking conditions

The purpose of the present work was to investigate the concentration ranges of H₂O₂ generated from cigarette smoke of selected Chinese brands and the effect of different smoking behaviors on the deliveries of H₂O₂. A simple, rapid and reliable fluorescence assay was developed for the measurement of H₂O₂ based on the catalytic activity of hemoglobin using 10-acetyl-3, 7-dihydroxyphenoxazine (Amplex Red) as the substrate. The proposed method was applied to determine the H₂O₂ deliveries from mainstream cigarette smoke of 30 Chinese (5 blended and 25 Virginia) and two reference cigarettes (3R4F and 1R5F) under two machine smoking regimes. Results showed that, under ISO smoking conditions, Chinese blended cigarettes had lower H₂O₂ yields than Chinese flue-cured cigarettes (mean value 2.41 vs. 4.69?μg?cig^?1, p?<?0.05). As expected, the deliveries of H₂O₂ for all cigarettes analyzed were higher under Canadian intense smoking conditions than those under ISO conditions (ISO mean 4.31?μg?cig^?1 vs. Canadian mean 5.96?μg?cig^?1, p?<?0.05). In addition, the ratios of H₂O₂ to nicotine yields were utilized to show the relative differences in yields among brands tested in this work and more than a twofold difference was found for most of selected Chinese blended and flue-cured cigarettes.     

College student involvement in cigarette smoking: the role of psychosocial and behavioral protection and risk.

A theory-based protection and risk model was applied to explain variation in college students' cigarette smoking. Key aims were to examine whether psychosocial and behavioral protective and risk factors can account for cross-sectional and developmental variation in smoking, and to examine whether protection moderates the impact of risk on smoking involvement. Data for this three-wave longitudinal study were collected in fall 2002, spring 2003, and spring 2004 from 549 male and 427 female first-semester college students at the University of Colorado, Boulder. A 32-page questionnaire was used, with content theoretically derived from the constructs in problem-behavior theory. Cigarette smoking (number of cigarettes smoked on an average day in the past month), three types of psychosocial protection (models protection, controls protection, support protection), three types of psychosocial risk (models risk, opportunity risk, and vulnerability risk), two types of behavioral protection (church involvement, academic achievement), and two types of behavioral risk (problem drinking, marijuana use) were assessed. Psychosocial and behavioral protective and risk factors accounted for significant variation in smoking involvement, and protection moderated the impact of risk. Findings were consistent, for the most part, for both genders and across three separate waves of data. Key predictors of smoking involvement included controls protection, models risk, vulnerability risk, behavioral protection, and behavioral risk. Antecedent protective and risk factors were associated with the initiation of smoking in the college setting. A model of protective and risk factors can be useful in understanding college smoking behavior and suggesting targets for intervention.     

Perceptions by Hispanics of channels and sources of health messages regarding cigarette smoking

OBJECTIVE: To identify the perceptions that two communities of urban Hispanics have of various sources and channels of information regarding cigarette smoking and to compare them with those of non-Hispanic whites. DESIGN: Random samples of subjects of both ethnic groups and of both genders were surveyed by telephone to determine the perceived credibility and motivating power of 13 different channels of information and of 14 different sources of cigarette smoking information. SUBJECTS: 544 Hispanics and 542 non-Hispanic whites from San Francisco, California and Houston, Texas, 18-65 years in age, of both genders. RESULTS: Differences in the proportion of respondents assigning various perceived qualities to sources and channels of information regarding cigarette smoking were found to exist across ethnic groups (Hispanics and non-Hispanic whites); the respondents' gender (particularly among Hispanics); and the acculturation level of the Hispanic respondents. Nevertheless, there was a cluster of channels (printed media and television news) and of sources (physicians, people with cancer, friends, and peers) that were positively evaluated by large proportions of the respondents in both ethnic groups. CONCLUSIONS: Hispanics differ from non-Hispanic whites in their evaluation of various possible sources and channels of information about tobacco control. Culturally appropriate interventions for Hispanics need to be designed so as to use those channels and sources of information that are more positively perceived by Hispanics.