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1.
可持续发展CIMS(S—CIMS)的体系结构及其实施策略研究   总被引:8,自引:0,他引:8  
在分析可持续发展和CIMS的战略意义的基础上,提出了可持续发展CIMS(S-CIMS)的概念,并结合S-CIMS的特点和体系结构对S-CIMS的信息流进行了详细分析,最后还根据我国的具体情况阐明了在我国实施S-CIMS的策略。  相似文献   

2.
简述了TW-CIMS总体结构,总体功能模型,核心的关键技术以及详细设计的概要,阐述了TW-CIMS详细设计的个性化特征,包括详细设计的原则、组织与人员配置、把握详细设计的方向,详细设计的难点与重点四方面内容,就TW-CIMS中存在的并带有一定普遍性的MRPⅡ的用户化改造,建立产品明细管理系统,以实现MRPⅡ与CAD/CAPP/CAE的集成两大关键技术提出了相应的实用化解决方案。  相似文献   

3.
重视GT在CIMS中的应用   总被引:2,自引:0,他引:2  
综合某工作企业的CIMS规划实际,说明了GT在CIMS中的应用。包括信息分类编码,GT-CAD,GT-CAPP,GT-CAM,GT-车间布局以及GT-生产计划编制。自始至终,从顶到下贯串GT主线。  相似文献   

4.
德国CIMS现状与发展趋势一、德国CIMS的现状1.组织机构80年代中期,德国政府的联邦研究、技术、科学和教育部(BMBF)在西德地区的高校中建立了十个面向小型企业、以CIM技术培训及转让为目标的中心(CIM-TT)。两德统一后,又在原东德地区的高校...  相似文献   

5.
向东  张根保 《机械》1998,25(6):2-5
将可持续发展的思想融于CIMS,提出了可持续发展CIMS(S-CIMS)的基本概念,在此基础上对S-CIMS的特点和体系结构进行了初步探讨,最后详细分析了S-CIMS各分系统之间的内在联系和信息交换。  相似文献   

6.
结合某工业企业的CIMS规划实际,说明了GT在CIMS中的应用。包括信息分类编码,GT-CAD,GT-CAPP,GTCAM,GT-车间布局以及GT-生产计划编制。自始至终、从顶到下贯串GT主线。  相似文献   

7.
在总结下年来CIMS研究,开发和应用中的成果,特别是着批推广应用试点工厂的初步实践经验的基础上,对推广CIMS提出了十点看法,这就是:CIMS是制造业的革命;推广CIMS是为了实现国民经济信息化;在推广中就以改革总揽全局;以管理为突破口;紧紧抓住系统的开放性和集成  相似文献   

8.
CIMS应用集成平台技术发展现状与趋势   总被引:15,自引:1,他引:15  
本文讨论了CIMS应用集成平台的产生背景和发展情况。给出了CIMS应用集成平台的定义、基本特性和功能,介绍了国内外几种典型集成平台产品的基本功能和系统结构,并对它们进行了比较。结合企业CIMS实施对集成平台支持工具的需求和计算机软件技术的发展趋势,探讨了CIMS应用集成平台的发展趋势。  相似文献   

9.
本文回顾了12年来我国CIMS研究、开发和应用的进程,总结了系统集成的三个发展阶段,即基于异构环境的信息集成、基于设计过程重建和优化的过程集成(如并行工程)以及面向全球制造的企业间集成(简称企业集成,如敏捷制造)。在每一个发展阶段中,信息技术和现代管理方法都是相辅相成地进行研究和应用的。从我国几十家企业的应用示范情况来看,我国CIMS的总体思路和技术路线是基本成功的。文章还总结了我国CIMS最主要的技术特点,即“系统论”的思想,强调多学科(除了技术学科以外,还包括管理和经济等学科)的协同发展以及理论与实践的紧密结合。  相似文献   

10.
从计算机集成制造系统(CIMS)概念设计入手,按照系统论观点,通过分析CIMS的基本构成及各组成部分之间的关系,将CIMS分为决策、产品设计、经营管理和生产实施,并进一步对生产实施的组成及其内外部环境进行了研究,指出柔性制造系统(FMS)是生产实施的一部分,并对FMS的实质、组成、任务和功能等进行了深入的分析。  相似文献   

11.
Cadmium, zinc, selenium, and copper were administered, singly or in combination, orally or subcutaneously. Experiment I included 32 calves of both sexes; six received Cd (two groups), Zn, Cd, and Zn, and Cd and Se (two groups) and one group was a control. In Experiment II (21 bulls), three were given Cd, Cd, and Cu, and Cd and Zn, respectively, and one group was a control. For light microscopy, in Experiment I the highest amounts of silver granules were present in the samples of liver, small intestine, and vesicular gland of all the exposed groups; in Experiment II the most affected organs were liver, kidney, and small intestine. For electron microscopy, in Experiment I, after administration of Cd and Zn, the highest amounts of granules were seen in the cytoplasm of hepatocytes and cells of the proximal and distal renal tubules and the lowest amounts were found in glandular cells of the pancreas. Administration of Cd and Se resulted in the presence of large numbers of granules in the nuclei and nucleoli of spermatogonies. In Experiment II, ingestion of Cd and Zn in feed led to the appearance of highest amounts of granules in the nucleoli, nuclei, and cytoplasm of cells in testes, kidneys, and pancreas. Following Cd intake, the highest accumulation of granules was observed in the nucleoli of hepatocytes and cells of the proximal and distal renal tubules. Combined Cd and Cu produced the highest number of granules in cells of the proximal and distal renal tubules and in the nucleoli and nuclei of germinal epithelium.  相似文献   

12.
To ascertain the possible implications of the nitric oxide (NO*) producing system in striatal senescence, and by using immunohistochemistry and image-processing approaches, we describe the presence of the enzyme nitric oxide synthase (NOS), the NADPH-diaphorase (NADPH-d) histochemical marker, and nitrotyrosine-derived complexes (N-Tyr) in the striatum of adult and aged rats. The results showed neuronal NOS immunoreactive (nNOS-IR) aspiny medium-sized neurons and nervous fibres in both age groups, with no variation in the percentage of immunoreactive area but a significant decrease in the intensity and in the number of somata with age, which were not related to the observed increase with age of the striatal bundles of the white matter. In addition, NADPH-d activity was detected in neurons with morphology similar to that of the nNOS-IR cells; a decrease in the percentage of area per field and in the number of cells, but an increase in the intensity of staining for the NADPH-d histochemical marker, were detected with age. The number of neuronal NADPH-d somata was higher than for the nNOS-IR ones in both age groups. Moreover, N-Tyr-IR complexes were observed in cells (neurons and glia) and fibres, with a significant increase in the percentage of the area of immunoreaction, related to the increase of white matter, but a decrease in intensity for the aged group. On the other hand, we did not detect the inducible isoform (iNOS) either in adult or in aged rats. Taken together, these results support the contention that NADPH-d staining is not such an unambiguous marker for nNOS, and that increased protein nitration may participate in striatal aging.  相似文献   

13.
The S100 protein in nervous tissue appears to play important roles in regulating neuronal differentiation, glial proliferation, plasticity, development, axonal growth, and in neurogenetic processes. In fish, the adult neurogenic activity is much higher than in mammals. In this study, the localization of S100 protein was investigated in the brain of annual teleost fish, Nothobranchius furzeri, which is an emerging model organism for aging research. By immunohistochemical techniques, S100 immunoreactivity (IR) was detected in glial cells, small neurons, and fibers throughout all regions of central nervous system (CNS) with different pattern of distribution. In the telencephalon, S100 IR was seen in the olfactory bulbs and in different areas of the telencephalic hemispheres. In the diencephalon, S100 positivity was observed in the habenular nuclei of the epithalamus, in the cortical thalamic nucleus, in the dorsal, ventral and caudal portions, the latter with the posterior recessus nucleus, and in the diffuse inferior lobe of the hypothalamus, along the diencephalic ventricle and in the dorsal optic tract. In the mesencephalon, S100 IR was observed in the longitudinal tori, in the optic tectum, and along the mesencephalic ventricle. In the rhombencephalon, S100 IR was shown in valvula and body of the cerebellum, and in some nuclei of the medulla oblongata. The results suggest that S100 may play a key role in the maintenance of the CNS and in neurogenesis processes in the adulthood.  相似文献   

14.
利用DTF型太阳光度计在我国几个典型城市地区较长期观测得到的资料,分析了不同地区气溶胶光学厚度日变化和季节变化特征,得到了各地区观测期间日均值、月均值和季节值的变化.结果显示,观测期间丽江地区气溶胶光学厚度最小,大气较洁净,大气中以细粒子为主;其次是张北;喀什和合肥地区气溶胶光学厚度都较大,但喀什、张北多以粗粒子为主,合肥多以细粒子为主.各地区都在春季气溶胶光学厚度较大,冬季最小.喀什的气溶胶光学厚度值多集中在0.15到0.7之间,张北多集中在0.08到0.4之间,合肥多集中在0.2到0.75之间,丽江多集中在0.01到0.1之间.各地区气溶胶光学厚度和(A)ngstr(o)m波长指数频率分布基本呈高斯分布,气溶胶光学厚度峰值分布由高到低依次为合肥、喀什、张北、丽江,(A)ngstr(o)m波长指数由高到低依次为丽江、合肥、张北、喀什.  相似文献   

15.
Investigations on the relations between the phase angle of the acoustic impedance at the driver piston and the system performance of a standing wave thermoacoustic cooler were performed. The system performance measured at a fixed acoustic power showed that the coefficient of performance of the standing wave thermoacoustic cooler increases as the phase angle increases when the stack temperature span is relatively low. The results were consistent with the simulation results obtained from DELTAE, a computer code based on linear thermoacoustic theory. Analysis on the temperature profiles along the stack showed that the cooling efficiency (COP) of the system could be decreased or increased as the phase angle of the acoustic impedance at the driver piston changes depending on the stack temperature spans. This paper was recommended for publication in revised form by Associate Editor Yeon June Kang Insu Paek received the B.S. degree in Mechatronics Engineering from Kangwon National University, Chuncheon, Korea, in 1997, the M.S. degree in Mechanical Engineering from the University of Texas at Austin, USA, in 2000, and the Ph. D. degree in Mechanical Engineering from Purdue University, West Lafayette, USA, in 2005. He worked as a postdoctoral researcher in Purdue University and McGill University in 2006 and 2007. He is currently a faculty member in the Department of Mechatronics Engineering, Kangwon National University, Chuncheon, Korea. His research interests include thermoacoustic cooling and power generation, solar heat driven absorption cooling., and wind power. Luc Mongeau received the B.S. and M.S. degrees in mechanical engineering from the University of Montreal, QC, Canada, in 1984 and 1986, respectively, and the Ph. D. degree in Acoustics from Pennsylvania State University, University Park, USA, in 1990. He is currently a professor in the Department of Mechanical Engineering at McGill University, Montreal, QC, Canada. He has published over 50 archival journal publications on various topics related to acoustics and noise control. His research activities are in the flow and turbomachinery noise areas, as well as in the areas of voice production, and thermoacoustic refrigeration. James E. Braun received the B.S. degree in Mechanical Engineering from the University of Massachusetts, USA, in 1976, and the M.S. and Ph. D. degrees in Mechanical Engineering from the University of Wisconsin, Madison, USA, in 1980 and 1988, respectively. He is currently a professor in the Department of Mechanical Engineering, Purdue University, West Lafayette, USA. Professor Braun’s research combines the use of computer modeling, optimization, and experiments to study and improve the performance of thermal systems. He has published over 140 papers. Professor Braun is currently an associate editor for the international journal of HVAC&R Research. Shin You Kang received the B.S. and M.S. degrees in the Department of Mechanical Design from Seoul National University, Seoul, Korea, in 1982, and 1986, respectively. He then received the Ph.D. in Mechanical Engineering at the same university in 1992. Professor Kang is currently a professor in the Department of Mechatronics Engineering, Kangwon National University, Chuncheon, Korea. His research interests include mechanical structure design, crash analysis, optimal design, computational structure analysis and evaluation.  相似文献   

16.
Developmental and seasonal changes in the production of androgens, estrogens, and progestins seem to control sex-specific differentiation and seasonal changes in appetitive and consummatory sexual behaviors of birds. This results in profound sex differences in the quality (sex-specific) or quantity (sex-typical) of behaviors such as courtship, territoriality, or copulation. Steroids affect the brain by binding to intracellularly located receptors. The same brain areas express androgen, estrogen, and progesterone receptors in male and female brains. Sex differences in these genetically determined patterns occur in the size of neuron populations that intrinsically express sex steroid receptors. Further permanent sex differences are subsequent to degenerative fates of receptor expressing neuron populations during ontogeny. Transient sex differences in receptor expression appear to be due to area-specific up- and down-regulation of receptor levels, reflecting transient changes in the level of circulating steroids, changes in environmental conditions, or in the physiological status of the individuals. In particular, intrinsic sex differences in the expression pattern of sex steroid receptors and steroid-independent regulation of the expression level of these receptors in the brain are limiting mechanisms for gonad-dependent sexual development and activities.  相似文献   

17.
Liver endothelial cells form a continuous lining of the liver capillaries, or sinusoids, separating parenchymal cells and fat-storing cells from sinusoidal blood. Liver sinusoidal endothelial cells differ in fine structure from endothelial cells lining larger blood vessels and from other capillary endothelia in that they lack a distinct basement membrane and also contain open pores, or fenestrae, in the thin cytoplasmic projections which constitute the sinusoidal wall. This distinctive morphology supports the protective role played by liver endothelium, the cells forming a general barrier against pathogenic agents and serving as a selective sieve for substances passing from the blood to parenchymal and fat-storing cells, and vice versa. Sinusoidal endothelial cells, furthermore, significantly participate in the metabolic and clearance functions of the liver. They have been shown to be involved in the endocytosis and metabolism of a wide range of macromolecules, including glycoproteins, lipoproteins, extracellular matrix components, and inert colloids, establishing endothelial cells as a vital link in the complex network of cellular interactions and cooperation in the liver. Fine structural studies in combination with the development of cell isolation and culture techniques from both experimental animal and human liver have greatly contributed to the elucidation of these endothelial cell functions. Morphological and biochemical investigations have both revealed little changes with age except for an accumulation of iron ferritin and a decrease in the activities of glucose-6-phosphatase, Mg-ATPase, and in glucagon-stimulated adenylcyclase. Future studies are likely to disclose more fully the role of sinusoidal endothelial cells in the regulation of liver hemodynamics, in liver metabolism and blood clearance, in the maintenance of hepatic structure, in the pathogenesis of various liver diseases, and in the aging process in the liver.  相似文献   

18.
Changes in the patterns of production and in the effects of signal substances may be involved in the development of tendinosis, a chronic condition of pain in human tendons. There is no previous information concerning the patterns of sympathetic innervation in the human patellar tendon. In this study, biopsies of normal and tendinosis patellar tendons were investigated with immunohistochemical methods, including the use of antibodies against tyrosine hydroxylase (TH) and neuropeptide Y, and against alpha1-, alpha2A-, and beta1-adrenoreceptors. It was noticed that most of the sympathetic innervation was detected in the walls of the blood vessels entering the tendon through the paratendinous tissue, and that the tendon tissue proper of the normal and tendinosis tendons was very scarcely innervated. Immunoreactions for adrenergic receptors were noticed in nerve fascicles containing both sensory and sympathetic nerve fibers. High levels of these receptors were also detected in the blood vessel walls; alpha1-adrenoreceptor immunoreactions being clearly more pronounced in the tendinosis tendons than in the tendons of controls. Interestingly, immunoreactions for adrenergic receptors and TH were noted for the tendon cells (tenocytes), especially in tendinosis tendons. The findings give a morphological correlate for the occurrence of sympathetically mediated effects in the patellar tendon and autocrine/paracrine catecholamine mechanisms for the tenocytes, particularly, in tendinosis. The observation of adrenergic receptors on tenocytes is interesting, as stimulation of these receptors can lead to cell proliferation, degeneration, and apoptosis, events which are all known to occur in tendinosis. Furthermore, the results imply that a possible source of catecholamine production might be the tenocytes themselves  相似文献   

19.
毕克新  赵林海 《中国机械工程》2001,12(12):1444-1446
在分析发展中国家制造业概况的基础上,针对发展中国家制造业的特点,论述了发展中国家制造业技术创新活动中所涉及到的技术预测,评价和选择,研究与开发,生产与营销,技术转移与技术贸易,知识产权保护及纠纷处理以及在WTO规则下的不利影响因素等。提出了基于WTO规则的发展中国家制造业技术创新发展的若干对策。  相似文献   

20.
Pituitary adenylate cyclase-activating polypeptide (PACAP), a novel peptide of the secretin/glucagon/vasoactive intestinal polypeptide superfamily, has been initially characterized in mammals in 1989 and, only 2 years later, its counterpart has been isolated in amphibians. A number of studies conducted in the frog Rana ridibunda have demonstrated that PACAP is widely distributed in the central nervous system (particularly in the hypothalamus and the median eminence) and in peripheral organs including the adrenal gland. The cDNAs encoding the PACAP precursor and 3 types of PACAP receptors have been cloned in amphibians and their distribution has been determined by in situ hybridization histochemistry. Ontogenetic studies have revealed that PACAP is expressed early in the brain of tadpoles, soon after hatching. In the frog Rana ridibunda, PACAP exerts a large array of biological effects in the brain, pituitary, adrenal gland, and ovary, suggesting that, in amphibians as in mammals, PACAP may act as neurotrophic factor, a neurotransmitter and a neurohormone.  相似文献   

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