Gain ratio based fuzzy weighted association rule mining classifier for medical diagnostic interface

The health care environment still needs knowledge based discovery for handling wealth of data. Extraction of the potential causes of the diseases is the most important factor for medical data mining. Fuzzy association rule mining is well-performed better than traditional classifiers but it suffers from the exponential growth of the rules produced. In the past, we have proposed an information gain based fuzzy association rule mining algorithm for extracting both association rules and member-ship functions of medical data to reduce the rules. It used a ranking based weight value to identify the potential attribute. When we take a large number of distinct values, the computation of information gain value is not feasible. In this paper, an enhanced approach, called gain ratio based fuzzy weighted association rule mining, is thus proposed for distinct diseases and also increase the learning time of the previous one. Experimental results show that there is a marginal improvement in the attribute selection process and also improvement in the classifier accuracy. The system has been implemented in Java platform and verified by using benchmark data from the UCI machine learning repository.     

Computer aided brain tumor detection system using watershed segmentation techniques

Magnetic Resonance Imaging (MRI) is an advanced medical imaging technique that has proven to be an effective tool in the study of the human brain. In this article, the brain tumor is detected using the following stages: enhancement stage, anisotropic filtering, feature extraction, and classification. Histogram equalization is used in enhancement stage, gray level co‐occurrence matrix and wavelets are used as features and these extracted features are trained and classified using Support Vector Machine (SVM) classifier. The tumor region is detected using morphological operations. The performance of the proposed algorithm is analyzed in terms of sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV). The proposed system achieved 0.95% of sensitivity rate, 0.96% of specificity rate, 0.94% of accuracy rate, 0.78% of PPV, and 0.87% of NPV, respectively. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 297–301, 2015     

改进的 AdaBoost人脸检测方法

针对传统 AdaBoost算法检测速度快准确率低的问题,本文提出了一种改进的 AdaBoost算法以提高人脸的正确检测率,该算法首先利用快速积分图提取人脸的 Haar特征,然后使用阈值设定的方法对传统的 AdaBoost算法进行改进,并将每次检测的最优弱分类器级联形成最终的强分类器,通过强弱分类器对 Haar特征判别,从而检测图像中的人脸部分。采用本方法对多种实验图像集进行人脸检测实验, FERET彩色图像库的正确检测率为96.07%,视频图像的正确检测率为 96%。实验结果表明,本文所设计的人脸检测算法能够对静态图像以及视频图像中的人脸进行有效检测,为人脸的正确识别打下了基础,该算法也为计算机视觉领域的研究提供一种有效方法。     

Detection and classification of microcalcification from digital mammograms with firefly algorithm,extreme learning machine and non-linear regression models: A comparison

In this study, abnormalities in medical images are analysed using three classifiers, and the results are compared. Breast cancer remains a major public health problem among women worldwide. Recently, many algorithms have evolved for the investigation of breast cancer diagnosis through medical imaging. A computer-aided microcalcification detection method is proposed to categorise the nature of breast cancer as either benign or malignant from input mammogram images. The standard mammogram image corpus, the Mammogram Image Analysis Society database is utilised, and feature extraction is performed using five different wavelet families at level 4 and level 6 decomposition. The work is accomplished through firefly algorithm (FA), extreme learning machine (ELM) and least-square-based non-linear regression (LSNLR) classifiers. The performance of the classifiers is compared by benchmark metrics, such as total error rate, specificity, sensitivity, area under the receiver operating characteristic curve, precision, F1 score and the Matthews correlation coefficient. As validation of the classifier results, a kappa analysis is included to determine the agreement among classifiers. The LSNLR classifier attains a 3% to 7% improvement in average accuracy compared with the average classification accuracy of the FA (86.75%) and ELM (90.836%) classifiers.     

MRI brain image classification—a hybrid approach

The present article proposes a novel computer‐aided diagnosis (CAD) technique for the classification of the magnetic resonance brain images. The current method adopt color converted hybrid clustering segmentation algorithm with hybrid feature selection approach based on IGSFFS (Information gain and Sequential Forward Floating Search) and Multi‐Class Support Vector Machine (MC‐SVM) classifier technique to segregate the magnetic resonance brain images into three categories namely normal, benign and malignant. The proposed hybrid evolutionary segmentation algorithm which is the combination of WFF(weighted firefly) and K‐means algorithm called WFF‐K‐means and modified cuckoo search (MCS) and K‐means algorithm called MCS‐K‐means, which can find better cluster partition in brain tumor datasets and also overcome local optima problems in K‐means clustering algorithm. The experimental results show that the performance of the proposed algorithm is better than other algorithms such as PSO‐K‐means, color converted K‐means, FCM and other traditional approaches. The multiple feature set comprises color, texture and shape features derived from the segmented image. These features are then fed into a MC‐SVM classifier with hybrid feature selection algorithm, trained with data labeled by experts, enabling the detection of brain images at high accuracy levels. The performance of the method is evaluated using classification accuracy, sensitivity, specificity, and receiver operating characteristic (ROC) curves. The proposed method provides highest classification accuracy of greater than 98% with high sensitivity and specificity rates of greater than 95% for the proposed diagnostic model and this shows the promise of the approach. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 226–244, 2015     

A new rectangular window based image cropping method for generalization of brain neoplasm classification systems

Classification of brain neoplasm images is one of the most challenging research areas in the field of medical image processing. The main objective of this study is to design a brain neoplasm classification system that can be trained using multiple various sized MR images of different institutions. The proposed method is a generalized classification system; it can be used in a single institute or in a number of institutions at the same time, without any restriction on image size. The generalization and unbiased capability of the proposed method can bring researchers on a single platform to work on some standard forms of computer aided diagnosis system with more efficient diagnostic capabilities. In this study, a suitable size of moveable rectangular window is used between segmentation and feature extraction stages. A semiautomatic, localized region based active contour method is used for segmentation of brain neoplasm region. Discrete wavelet transform for feature extraction, principal component analysis for feature selection and support vector machine is used as classifier. For the first time MR images of 2 sizes and from different institutions are used in training and testing of brain neoplasm classifier. Three glioma grades were classified using 92 MR images. The proposed method achieved the highest accuracy of 88.26%, the highest sensitivity of 92.23% and the maximum specificity of 93.93%. In addition, the proposed method is computationally less complex, requires shorter processing time and is more efficient in terms of storage capacity.     

Fractional gravitational search-radial basis neural network for bone marrow white blood cell classification

Automotive image segmentation systems are becoming an important tool in the medical field for disease diagnosis. The white blood cell (WBC) segmentation is crucial, because it plays an important role in the determination of the diseases and helps experts to diagnose the blood disease disorders. The precise segmentation of the WBCs is quite challenging because of the complex contents in the bone marrow smears. In this paper, a novel neural network (NN) classifier is proposed for the classification of the bone marrow WBCs. The proposed NN classifier integrates the fractional gravitation search (FGS) algorithm for updating the weight in the radial basis function mapping for the classification of the WBC based on the cell nucleus feature. The experimentation of the proposed FGS-RBNN classifier is carried on the images collected from the publically available dataset. The performance of the proposed methodology is evaluated over the existing classifier approaches using the measures accuracy, sensitivity, and specificity. The results show that the classification using the nucleus features alone can be utilized to achieve the classification with the better accuracy. Moreover, the classification performance of the proposed FGS-RBNN is better than the existing classifiers, and it is proved to be the efficacious classifier with a classification accuracy of 95%.     

An efficient automated methodology for detecting and segmenting the ischemic stroke in brain MRI images

Brain tumor and brain stroke are two important causes of death in and around the world. The abnormalities in brain cell leads to brain stroke and obstruction in blood flow to brain cells leads to brain stroke. In this article, a computer aided automatic methodology is proposed to detect and segment ischemic stroke in brain MRI images using Adaptive Neuro Fuzzy Inference (ANFIS) classifier. The proposed method consists of preprocessing, feature extraction and classification. The brain image is enhanced using Heuristic histogram equalization technique. Then, texture and morphological features are extracted from the preprocessed image. These features are optimized using Genetic Algorithm and trained and classified using ANFIS classifier. The performance of the proposed ischemic stroke detection system is analyzed in terms of sensitivity, specificity, accuracy, positive predictive value, negative predictive value, and Mathew's correlation coefficient.     

Computer aided automated detection and classification of brain tumors using CANFIS classification method

The development of abnormal cells in human brain leads to the formation of tumors. This article proposes an efficient approach for brain tumor detection and segmentation using image fusion and co-active adaptive neuro fuzzy inference system (CANFIS) classification method. The brain MRI images are fused and the dual tree complex wavelet transform is applied on the fused image. Then, the statistical features, local ternary pattern features and gray level co-occurrence matrix features. These extracted features are classified using CANFIS classification approach for the classification of source brain MRI image into either normal or abnormal. Further, morphological operations are applied on the abnormal brain MRI image for segmenting the tumor regions. The proposed methodology is evaluated with respect to the performance metrics sensitivity, specificity, positive predictive value, negative predictive value, tumor segmentation accuracy with detection rate. The proposed image fusion based brain tumor detection and classification methodology stated in this article achieves 96.5% of average sensitivity, 97.7% of average specificity, 87.6% of positive predictive value, 96.6% of negative predictive value, and 98.8% of average accuracy.     

Automated detection of glioblastoma tumor in brain magnetic imaging using ANFIS classifier

This article proposes a novel and efficient methodology for the detection of Glioblastoma tumor in brain MRI images. The proposed method consists of the following stages as preprocessing, Non‐subsampled Contourlet transform (NSCT), feature extraction and Adaptive neuro fuzzy inference system classification. Euclidean direction algorithm is used to remove the impulse noise from the brain image during image acquisition process. NSCT decomposes the denoised brain image into approximation bands and high frequency bands. The features mean, standard deviation and energy are computed for the extracted coefficients and given to the input of the classifier. The classifier classifies the brain MRI image into normal or Glioblastoma tumor image based on the feature set. The proposed system achieves 99.8% sensitivity, 99.7% specificity, and 99.8% accuracy with respect to the ground truth images available in the dataset.     

CANFIS based glioma brain tumor classification and retrieval system for tumor diagnosis

Brain tumor classification and retrieval system plays an important role in medical field. In this paper, an efficient Glioma Brain Tumor detection and its retrieval system is proposed. The proposed methodology consists of two modules as classification and retrieval. The classification modules are designed using preprocessing, feature extraction and tumor detection techniques using Co‐Active Adaptive Neuro Fuzzy Inference System (CANFIS) classifier. The image enhancement can be achieved using Heuristic histogram equalization technique as preprocessing and further texture features as Local Ternary Pattern (LTP) features and Grey Level Co‐occurrence Matrix (GLCM) features are extracted from the enhanced image. These features are used to classify the brain image into normal and abnormal using CANFIS classifier. The tumor region in abnormal brain image is segmented using normalized graph cut segmentation algorithm. The retrieval module is used to retrieve the similar segmented tumor regions from the dataset for diagnosing the tumor region using Euclidean algorithm. The proposed Glioma Brain tumor classification methodology achieves 97.28% sensitivity, 98.16% specificity and 99.14% accuracy. The proposed retrieval system achieves 97.29% precision and 98.16% recall rate with respect to ground truth images.     

Automated diagnosis system for age‐related macular degeneration using hybrid features set from fundus images

Impairment to macula can cause loss of central vision. There are various macular disorders that can affect macular region and if not treated at an early stage can cause irreversible central vision loss. Age‐related macular degeneration (AMD) disorder is one of the most threading macular disorder. Bright lesion, drusens presence in macular region is known as the hallmark of AMD disorder. This bright lesion differentiation from other bright lesion like exudates is important for accurate diagnosis of AMD. Focus of this article is automated diagnosis of affected macular region by applying a hybrid features set containing textural, color, and structural/shape features for more accurate detection of AMD at an early stage using fundus images. These features also help to distinguish drusens from exudates. The proposed algorithm at first stage, detect macular region from input fundus image and then perform features extraction based on textural pattern, edge, and structural properties of macular region to classify abnormal macula from normal macula. For classification, we have used support vector machine (SVM), K‐nearest neighbor and neural networks but SVM classifier achieves high accuracy. The proposed algorithm is tested on publicly available STARE and locally available AFIO datasets. Attained sensitivity, specificity, and accuracy of our proposed system are 97.5%, 95% and 95.45%, respectively, when applied on STARE dataset. When we have applied our proposed system on AFIO dataset, we have attained sensitivity, specificity, and accuracy of 93.3%, 92% and 92.34%, respectively.     

Data-mining-based dynamic dispatching rule selection mechanism for shop floor control systems using a support vector machine approach

The purpose of this paper is to develop a data-mining-based dynamic dispatching rule selection mechanism for a shop floor control system to make real-time scheduling decisions. In data mining processes, data transformations (including data normalisation and feature selection) and data mining algorithms greatly influence the predictive accuracy of data mining tasks. Here, the z-scores data normalisation mechanism and genetic-algorithm-based feature selection mechanism are used for data transformation tasks, then support vector machines (SVMs) is applied for the dynamic dispatching rule selection classifier. The simulation experiments demonstrate that the proposed data-mining-based approach is more generalisable than approaches that do not employ a data-mining-based approach, in terms of accurately assigning the best dispatching strategy for the next scheduling period. Moreover, the proposed SVM classifier using the data-mining-based approach yields a better system performance than obtained with a classical SVM-based dynamic dispatching rule selection mechanism and heuristic individual dispatching rules under various performance criteria over a long period.     

Automated screening of glaucoma stages from retinal fundus images using BPS and LBP based GLCM features

Glaucoma is an eye disease in which the retinal nerve fibers are irreversibly damaged. Early identification of glaucoma is essential because it may slow the progression of the illness. The clinical treatments and medical imaging methods that are currently available are all manual and require expert supervision. An automated glaucoma diagnosis system that is fast, accurate, and helps to reduce the load on professionals is necessary for mass screening. In our proposed work, a novel approach based on bit-plane slicing (BPS), local binary pattern (LBP), and gray-level co-occurrence matrix (GLCM) is used. First, fundus images are separated into channels like red, green, and blue, and these separated channels are split into plans using BPS. Then, LBP images are obtained from selected green channel images. Second, we extract features based on GLCM from LBP images. Finally, using a least-squares support vector machine classifier, the higher ranked features are employed to classify glaucoma stages. According to the findings of the experiments, our model outperformed state-of-the-art approaches for glaucoma classification. Using 10-fold cross-validation, this model achieved an improved classification accuracy of 95.04%, specificity of 96.37%, and sensitivity of 93.77%. We conducted many relative experiments with deep learning and traditional machine learning-based models to test our proposed methodology. Compared to existing glaucoma classification approaches, the new method has been shown to be more efficient.     

Detection and Classification of Diabetic Retinopathy Using DCNN and BSN Models

Diabetes is associated with many complications that could lead to death. Diabetic retinopathy, a complication of diabetes, is difficult to diagnose and may lead to vision loss. Visual identification of micro features in fundus images for the diagnosis of DR is a complex and challenging task for clinicians. Because clinical testing involves complex procedures and is time-consuming, an automated system would help ophthalmologists to detect DR and administer treatment in a timely manner so that blindness can be avoided. Previous research works have focused on image processing algorithms, or neural networks, or signal processing techniques alone to detect diabetic retinopathy. Therefore, we aimed to develop a novel integrated approach to increase the accuracy of detection. This approach utilized both convolutional neural networks and signal processing techniques. In this proposed method, the biological electro retinogram (ERG) sensor network (BSN) and deep convolution neural network (DCNN) were developed to detect and classify DR. In the BSN system, electrodes were used to record ERG signal, which was pre-processed to be noise-free. Processing was performed in the frequency domain by the application of fast Fourier transform (FFT) and mel frequency cepstral coefficients (MFCCs) were extracted. Artificial neural network (ANN) classifier was used to classify the signals of eyes with DR and normal eye. Additionally, fundus images were captured using a fundus camera, and these were used as the input for DCNN-based analysis. The DCNN consisted of many layers to facilitate the extraction of features and classification of fundus images into normal images, non-proliferative DR (NPDR) or early-stage DR images, and proliferative DR (PDR) or advanced-stage DR images. Furthermore, it classified NPDR according to microaneurysms, hemorrhages, cotton wool spots, and exudates, and the presence of new blood vessels indicated PDR. The accuracy, sensitivity, and specificity of the ANN classifier were found to be 94%, 95%, and 93%, respectively. Both the accuracy rate and sensitivity rate of the DCNN classifier was 96.5% for the images acquired from various hospitals as well as databases. A comparison between the accuracy rates of BSN and DCNN approaches showed that DCNN with fundus images decreased the error rate to 4%.     

A deep learning model integrating convolution neural network and multiple kernel K means clustering for segmenting brain tumor in magnetic resonance images

In medical imaging, segmenting brain tumor becomes a vital task, and it provides a way for early diagnosis and treatment. Manual segmentation of brain tumor in magnetic resonance (MR) images is a time‐consuming and challenging task. Hence, there is a need for a computer‐aided brain tumor segmentation approach. Using deep learning algorithms, a robust brain tumor segmentation approach is implemented by integrating convolution neural network (CNN) and multiple kernel K means clustering (MKKMC). In this proposed CNN‐MKKMC approach, classification of MR images into normal and abnormal is performed by CNN algorithm. At next, MKKMC algorithm is employed to segment the brain tumor from the abnormal brain image. The proposed CNN‐MKKMC algorithm is evaluated both visually and objectively in terms of accuracy, sensitivity, and specificity with the existing segmentation methods. The experimental results demonstrate that the proposed CNN‐MKKMC approach yields better accuracy in segmenting brain tumor with less time cost.     

Hybrid features and optimization-driven recurrent neural network for glaucoma detection

Glaucoma is considered as the main source of irrevocable loss of vision. The earlier diagnosis of glaucoma is essential to provide earlier treatment and to reduce vision loss. The fundus images are transfigured in the ophthalmology and are used to visualize the structures of the optic disc. However, accuracy is considered as a major constraint. To increase accuracy, an effective optimization-driven classifier is developed for glaucoma detection. The proposed Jaya-chicken swarm optimization (Jaya-CSO) is employed for training the recurrent neural network (RNN) for glaucoma detection. The proposed Jaya-CSO is designed by integrating the Jaya algorithm with the chicken swarm optimization (CSO) technique for tuning the weights of the RNN classifier. The method utilized optic disc features, statistical features, and blood vessel features for the determination of the glaucomatous region. The features obtained from the optic disc, blood vessels, and the fundus image is formulated as a feature vector. Finally, the glaucoma classification is done using RNN using the feature vector such that the RNN is trained using the proposed Jaya-CSO. The proposed Jaya-CSO outperformed other existing models with maximal accuracy of 0.97, the specificity of 0.97, and sensitivity of 0.97, respectively.     

Factorization-based active contour segmentation and pelican optimization-based modified bidirectional long short-term memory for ovarian tumor detection

This paper proposes a novel three-dimensional convolution neural network-based modified bidirectional long short-term memory with pelican optimization (3D CNN based MBiLSTM with PO) algorithm for multiclass ovarian tumor detection. Initially, the International Collaboration on Cancer Reporting endometrial cancer dataset images are provided in pre-processing phase, which uses a pre-emphasis filter to process the input image. In the segmentation phase, pre-processed data is then partitioned into diverse subgroups (i.e., pixels), which minimizes the complexity of images. In this paper, a factorization-based active contour technique is employed in the effective segmentation of images. The segmented features are then extracted and classified using the 3D CNN-MBiLSTM with PO algorithm. Finally, the experimental results are conducted and compared with various other approaches for various performance metrics. Each metric is evaluated with respect to the different number of iterations. The accuracy, sensitivity, and specificity have reached a higher value of 98.5%, 96%, and 98.25%, respectively.     

基于小波融合的电容层析成像图像重建

提出了基于小波变换的电容层析成像重建图像融合方法。首先,使用共轭梯度最小二乘法算法及Landweber迭代算法分别进行图像重建;其次,将所得重建图像进行小波分解,其近似分量按加权平均的融合规则进行处理,细节分量按绝对值最大融合规则进行处理;最后,将融合之后的数据进行小波重构,获得新的重建图像。仿真及实验结果表明,融合后的重建图像精度有所提高、图像伪影明显减少。