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1.
The aim of the editorial note is to introduce the scope of this special issue (SI). We explain our editorial approach and provide a brief summary of eight articles included in the SI following multiple rounds of reviews. Finally, we outline future research questions which stemmed out of the discussions of this SI.  相似文献   

2.
While logistics research recently has placed increased focus on disruption management, few studies have examined the response and recovery phases in post-disaster operations. We present a multiple objective, integrated network optimisation model for making strategic decisions in the supply distribution and network restoration phases of humanitarian logistics operations. Our model provides an equity-based solution for constrained capacity, budget and resource problems in post-disaster logistics management. We conduct designed experiments for this NP-hard problem to analyse important aspects of the integrated problem for both small- and large-sized networks: full vs. partial restoration and pooled vs. separate budgeting approach. Finally, we apply the model to a Hazus-generated regional case study based on an earthquake scenario and generate efficient Pareto frontiers to understand the trade-off between the objectives of interest.  相似文献   

3.
Trust between partners, a key element enabling coordination across supply chains, has recently started gaining attention in humanitarian operations literature. Yet, empirical examination of this concept is scant. Borrowing from extant literature on trust within organisational behaviour stream, this paper aims to empirically verify trust formation types: companion, competence and commitment, in a disaster relief supply chain using primary and secondary data from an Indian Humanitarian relief organisation (HRO). Further, we identify variations in trust formation during disaster relief activities and developmental programmes, and between upstream and downstream partners of a humanitarian relief organisation. Based on the results of our content analysis, we contend that while companion based trust is significantly more prevalent during developmental programmes, competence based trust is important during both disaster periods and otherwise. We also find that there are significant differences in the trust formation between upstream and downstream partners and the HRO. This study has significant theoretical and practical implications on identifying the role of trust in humanitarian operations.  相似文献   

4.
There has been tremendous interest in blockchain technology (BT) (also known as distributed ledger technology) around the globe and across sectors. Following significant success in the financial sector, other sectors, such as humanitarian sector, have started deploying BT at various levels. Although the use of BT in the humanitarian sector is in its infancy, donors and government agencies are increasingly calling for building BT-enabled swift-trust (ST) and more collaborative relationships among various humanitarian actors in order to improve the transparency and traceability of disaster relief materials, information exchanges and flow of funds in disaster relief supply chains. Our study, which is informed by organisational information processing theory and relational view, proposes a theoretical model to understand how BT can influence operational supply chain transparency (OSTC) and ST among actors engaged in disaster relief operations. Our model also shows how BT-enabled ST can further improve collaboration (CO) among actors engaged in disaster relief operations and enhance supply chain resilience (SCR). We formulated and tested six research hypotheses, using data gathered from international non-governmental organisations with the help of the Coordinator for Humanitarian Affairs (OCHA) database. We received 256 usable responses using a pre-tested survey-based instrument designed for key informants. Our results confirm that our six hypotheses were supported. Our study offers significant and valid contributions to the literature on ST, CO and SCR and BT/distributed ledger technology. We have also noted the limitations of our study and have offered future research directions.  相似文献   

5.
Cancers are rarely caused by single mutations, but often develop as a result of the combined effects of multiple mutations. For most cells, the number of possible cell divisions is limited because of various biological constraints, such as progressive telomere shortening, cell senescence cascades or a hierarchically organized tissue structure. Thus, the risk of accumulating cells carrying multiple mutations is low. Nonetheless, many diseases are based on the accumulation of such multiple mutations. We model a general, hierarchically organized tissue by a multi-compartment approach, allowing any number of mutations within a cell. We derive closed solutions for the deterministic clonal dynamics and the reproductive capacity of single clones. Our results hold for the average dynamics in a hierarchical tissue characterized by an arbitrary combination of proliferation parameters. We show that hierarchically organized tissues strongly suppress cells carrying multiple mutations and derive closed solutions for the expected size and diversity of clonal populations founded by a single mutant within the hierarchy. We discuss the example of childhood acute lymphoblastic leukaemia in detail and find good agreement between our predicted results and recently observed clonal diversities in patients. This result can contribute to the explanation of very diverse mutation profiles observed by whole genome sequencing of many different cancers.  相似文献   

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