65例小儿过敏性紫癜的护理体会

总结了65例小儿过敏性紫癜的护理要点,主要护理措施是依据临床特征采取针对性护理措施.认为在治疗过程中,正确指导患儿日常生活与学习,并采取综合性护理,对小儿过敏性紫癜的恢复与预后起着重要的作用.     

小儿过敏性紫癜的护理

总结了89例小儿过敏性紫癜的护理体会,主要护理措施包括心理护理、皮肤护理、饮食护理、疼痛护理、紫癜性肾炎的护理和用药护理.认为有效治疗和精心护理对该病的恢复起着重要的作用.     

过敏性紫癜60例临床发病治疗研究

目的:探讨过敏性紫癜(HSP)的临床发病及诊治特点.方法:回顾性分析60例HSP患者的临床资料,对HSP的发病特点,临床表现及肾损害等方面资料.结果:60例患者中有46例经治愈出院 (占76.7%),症状、体征恢复正常,尿常规仍有异常者44例(占23.3%).结论:HSP发病诱因以感染占首位,合并肾损害常见,皮肤紫癜反复或合并消化道症状明显者肾脏更易受累.     

24例小儿过敏性紫癜综合治疗的临床分析

目的:探讨过敏性紫癜(HSP)的临床疗效.方法:回顾分析24例患者的临床资料.结果:24例均于1周内症状改善,21例于10～14天后痊愈出院,随访1年无复发.2例于出院2周后复发,仅见少许皮疹,口服强的松治愈,随访1年无复发.1例形成了紫癜性肾炎,经过免疫抑制剂环磷酰胺、中药等治疗,随访1年无加重.结论:单纯性HSP临床治疗,疗程最短,疗效最理想,合并肾脏改变的病例病程较长.     

中药治疗小儿过敏性紫癜52例临床观察

目的:观察中药治疗小儿过敏性紫癜的临床疗效.方法:98例过敏性紫癜患儿随机分为治疗组52例,对照组46例,对照组以西药治疗,治疗组在其基础上加服中药.两组分别治疗三周后,比对两组疗效.结果:总有效率,治疔组96.1%,对照组80.4%,(P＜0.05)皮疹消退时间及尿常规恢复正常时间均短于对照组.结论:中药治疗小儿过敏性紫癜具有显著疗效,病程短,值得推广.     

40例合并心脏损害的儿童过敏性紫癜临床分析

目的:探讨过敏性紫癜患儿合并心脏损害的病理机制、临床特点以及诊断和治疗.方法:选择过敏性紫癜合并心脏损害患儿40例,检查、观察其心电图及心肌酶学改变,并对其不同分型作对比分析.结果:心电图异常25例,其中混合型19例,单纯型6例.心肌酶谱异常的27例中,混合型18例,单纯型9例,混合型病例心肌酶谱高于单纯型.恢复期心肌酶及心电图均可恢复正常.结论:过敏性紫癜合并心肌损害,混合型病例更为多见.对过敏性紫癜患儿应及早行心电图、心肌酶谱的检查,以及时预防和治疗心脏损害.     

中西医结合治疗小儿过敏性紫癜68例疗效观察

目的:观察中西医结合治疗小儿过敏性紫癜的临床疗效.方法:将133例小儿过敏性紫癜患儿随机分为治疗组68例,对照组65例,对照组采用单纯西药治疗,治疗组在对照组的基础上加服中药,14d后观察疗效.结果:治疗组临床治愈率为83 8%,总有效率95.6%,对照组临床治愈率为76.8%,总有效率为84.6%.结论:中西医结合治疗小儿过敏性紫癜可提高疗效,缩短病程,值得临床推广使用.     

肝纤维化血清标记物检测分析

目的:通过对肝病患者肝纤维化血清标记物测定分析,找出有助于肝纤维化诊断的实验指标.方法:采用酶联免疫吸附试验方法,测定肝病患者血清中HA、LN、CⅣ、PCⅢ的含量.结果:HA、LN、CⅣ、PCⅢ的含量随着病情发展而升高.结论:血清HA、LN、CⅣ、PCⅢ的联合检测有助于硬化的诊断和治疗.     

妊娠合并哮喘孕妇血清IgE水平与哮喘病情变化关系的研究

目的 探讨妊娠合并哮喘孕妇血清IgE水平与哮喘病情变化的关系.结果 选择70例不同严重程度的妊娠合并哮喘孕妇,运用酶联免疫吸附法对其过敏原特异性IgE抗体进行检测.结果过敏原特异性IgE抗体的阳性率以屋尘和螨虫阳性率最高;各组妊娠合并哮喘孕妇总IgE抗体阳性结果与检出过敏原种类差异有显著性意义.结论 妊娠合并哮喘孕妇哮喘发作的主要诱因是屋尘和户尘螨;其严重程度与血清总IgE水平的高低呈正相关;对多种抗原表现特异性IgE阳性者往往病情较重.     

脑卒中患者血清心肌酶谱、血糖检测的意义

临床上治疗脑卒中同时应动态观察心肌酶谱及血糖变化,一旦出现心肌损害现象应及时调整治疗方案,保护心脏功能以防止永久性心肌损害的发生.     

Non-specific airway hyperresponsiveness in mono-sensitive Sicilian patients with allergic rhinitis. Its relationship to total serum IgE levels and blood eosinophils during and out of the pollen season

BACKGROUND: Initial attempts to evaluate the association between allergic rhinitis and non-specific bronchial responsiveness has produced conflicting results. In fact, some studies showed a strong correlation and other failed to find an association. However, little is known about the effect of natural specific allergen exposure on the bronchial reactivity of mono-sensitive patients with rhinitis in the southern Mediterranean area, in relation to skin reactivity to allergens, total serum IgE levels and blood eosinophils. OBJECTIVES: The significance of the association between allergic rhinitis, and abnormal airway responsiveness with regard to the pathogenesis of asthma is unclear. For this reason, we have studied non-specific bronchial hyperreactivity, in patients with seasonal allergic rhinitis, with reference to the responsible allergen. The aim of the study was to correlate the responsiveness to bronchoprovocation with methacholine in subjects a with allergic rhinitis during and out of the pollen season with total serum IgE and blood eosinophils. METHODS: Fourty-nine non-smoking patients with clinical diagnosis of allergic rhinitis and mono-sensitive skin-prick tests to pollen allergens were enrolled in the study. Twenty patients suffered from seasonal rhinitis to Parietaria pollen, 15 patients to Gramineae pollen and 14 patients to Olea pollen. In all patients lung function measurements (assessed as response to methacholine), total serum IgE and blood eosinophil counts were measured during and out of the pollen season. RESULTS: During pollen season, 16 out of 49 rhinitis patients demonstrated values of bronchial responsiveness measured as response to inhaled methacholine in the asthmatic range whereas out of the pollen season only eight patients were in the asthmatic range. By analysing the results with reference to the responsible allergen, during the pollen season 15 out of 16 patients were Parietaria-sensitive and out of the pollen season seven out of eight patients. Finally, in Parietaria-sensitive rhinitis bronchial responsiveness significantly correlated, during and out of the pollen season, with total serum IgE and with blood eosinophil counts. CONCLUSIONS: Our results are consistent with the hypothesis that Parietaria is more important than Olea and Gramineae as a risk for developing non-specific bronchial hyperresponsiveness. On the whole, present observations provide further evidence that there is an interrelationship of allergen kind, total serum IgE, eosinophil and bronchial hyperresponsiveness suggesting that they may play a role in the development of bronchial asthma in rhinitis patients.     

Comparison among delayed-type skin tests, serum IgE levels and peripheral blood CD4 in HIV-positive patients

Three groups of HIV-positive men and a control group of healthy subjects were evaluated simultaneously by delayed-type skin tests with recall antigens detection of CD4 cell counts in peripheral blood and the IgE serum levels. Delayed-type skin test reactivity and CD4 cell counts in peripheral blood decreased while IgE serum levels increased as immune imbalance progressed with the worsening of HIV infection (p = 0.003 between controls and HIV-positive patients). The existence of atopy did not significantly influence IgE serum levels in the groups of HIV-positive patients (p < 0.2). Candidin appeared as a useful antigen in the delayed-type skin tests considering that it was the only antigen that remained positive with low values of CD4 cell counts (< or = 250/mm3). The detection of serum IgE levels as well as the performance of delayed-type skin tests with recall antigens are useful tools to evaluate immunological status whereas the number of CD4 in peripheral blood is critical for determining the initiation of antiretroviral therapy.