钕激光照射小鼠肿瘤对其体内免疫过程的影响

本文就钕激光照射小鼠带有黑色素肿瘤细胞和对体液的免疫性变化情况进行了实验研究，其结果证明激光照射具有促进机体免疫系统的抗肿瘤作用。     

激光微束照射对蛙卵发育影响的初步研究

一、前言激光微束照射技术在生物学上的应用才有十多年的历史,自从1962年 Bessis 等人首先应用红宝石激光微光束对生物细胞进行显微照射以来,应用激光微束技术研究生物发育机理方面越来越被人们所重视。它可以用来破坏一个细胞卵子或胚胎的某一部分,比之用机械的显微技术更为准确,更为简单,并可以避免由     

激光照射对蓖麻蚕血清蛋白的影响

我们采用不同波长的激光照射蓖麻蚕蚕卵，使它产生半致互效应，经孵化后的幼虫在五龄期取血分析它的血清蛋白谱，证实了激光照射对蓖麻蚕的遗传性状具有诱变作用，其机理涉及到激光照射与基因表达及调控的关系。     

激光照射时间对治疗鲜红斑痣的影响

激光照射时间对治疗鲜红斑痣的影响１引言鲜红斑涛是皮肤中毛细血管的畸形造成离散的粉红、红色或深红色的斑块。这些毛细血管的畸形损毁了患者的容貌，使其在社交活动中，尤其是在和异性交往中倍受痛苦，因此鲜红斑病的患者求治的心情极为迫切，促使人们寻求最佳的治疗方...     

激光照射对运动损伤康复效果影响研究

为使运动员的身体健康得到保障,研究了激光照射对运动损伤康复效果的影响。将不同运动员分为对照组和激光照射组,采用复合激光治疗仪对激光照射组实施不同剂量的激光治疗,采用生物化学法和显微观察法测试SOD活性、MDA含量、骨骼肌蛋白质生成率、羟脯氨酸含量等指标,衡量激光照射对运动损伤的影响。实验证明:52 J/cm²激光照射组的SOD活性、NOS活性、NO含量、SOD/MDA比值、NO/MDA比值与肌纤维结蛋白明显高于静止对照组与运动对照组,骨骼肌蛋白质生成率与羟脯氨酸含量明显高于运动对照组,具有良好的炎细胞抑制效果,MDA含量低于静止对照组与运动对照组,神经坏死率与CK活性明显低于运动对照组。综上所述,激光照射有助于运动损伤的康复,激光照射剂量越高,康复效果越好。     

紫外准分子激光照射对生物材料改性影响

近二十年国内外致力研究激光用于材料表面的改性,成为发展极为迅速的一门高新技术。医用生物材料直接与人体接触,要求材料表面与人体组织相容。激光表面处理可望改善医用生物材料的生物相容性。本文利用准分子激光对三种生物材料表面处理,得到了激光照射的最佳脉冲参数。准分子激光照射材料表面后,通过培养细胞的比对实验,显微镜观察证实处理后生物材料的生物相容性比处理前有明显的提高。证明激光表面处理有助于提高材料的生物相容性。     

激光照射对CFU-s和CFU-e增殖的影响

低剂量的He-Ne澈光照射可使多向性造血干细胞（CFU-s）和粒系定向干细胞（CFE-e）的增殖能力增加。将激光处理的骨髓细胞从静脉辅注给900拉德^60Co-γ射线照射的受体小鼠，从第三天开始股骨有核细胞数及CFU-1含量明显增多。     

激光照射对荷瘤小鼠淋巴细胞活性的影响

采用MTT还原分析法研究氦氖激光照射对SP2 /O骨髓瘤小鼠脾细胞、胸腺细胞的增殖活性的影响。结果表明激光具有增强荷瘤小鼠免疫细胞活性的功能。激光组与对照组相比P <0 0 1,差异明显。由此证明氦氖激光照射免疫器官区 (脾区 )具有活化淋巴细胞 ,促进淋巴细胞DNA合成 ,提高机体免疫力的作用。     

Immunomodulating effect of cyclophosphamide in experimental chemotherapy of transplanted tumors

A comparative morphofunctional analysis of lymphoid cells of BALB/c mice with the transplantable tumours was performed after the cyclophosphamide (CP) treatment. CP was injected by 3 schemes in a dose of 200 mg/kg of body weight. It was found that the more effective therapeutic scheme of CP treatment is accompanied by essential normalization of the ratio of lymphocyte populations in the lymph nodes against a background of a comparatively good state of proliferating cells as well as by a higher rate of restoration of proliferative responses to T and B cell mitogens in vivo.     

He-Ne激光血卟啉杀死动物移植肝癌的研究

应用大功率He—Ne激光血卟啉杀死动物移植肝癌的技术及其操作方法;并对治疗机理进行了探讨。     

三结太阳电池栅线对激光辐照中的传热影响研究

为了研究三结太阳电池表面的栅线在1 070 nm连续激光辐照过程中的传热影响机制,文中通过激光辐照过程中三结太阳电池实时的电致发光现象分析三结太阳电池的损伤情况,并建立三维锗基太阳电池模型,借助有限元分析软件COMSOL对连续激光辐照锗基太阳电池的温度分布进行仿真。结果表明:在连续激光功率密度为72.5 W/cm2、辐照时间为41 s时,三结太阳电池的顶电池出现轻微损伤,损伤区域首先沿着栅线分布。在锗基太阳电池的仿真模型中,电池的温度升高至1 318 K,栅线引起了三结太阳电池热量传递方向的各项异性,沿着栅线具有更高的热传导速率。仿真结果能够对实验现象给予合理的解释。     

高功率激光束近地面大气传输研究

本文报导连续波高功率CO2激光束的近地面大气传输特性研究,激光功率为3kW～5kW,传输距离为77m～107m,获得了由于光束畸变和大气影响引起的接收光斑变化图样.     

Characteristics of the metastatic spread of transplanted tumors under high-altitude conditions

The data on nature of metastatic spreading of transplantable animal tumours of the Tien-Shan mountains at an altitude of 3200 m above sea level are reviewed. It is shown that the adaptation of mice with Ehrlich adenocarcinoma is followed by the primary tumour growth inhibition and a two-fold decrease of frequency of metastatic spreading into regional lymph nodes as compared with the control animals at sea level. In mountains the activity of metastatic spreading into lungs of Lewis lung carcinoma and Walker carcinosarcoma decreases. In experiments with (CBA x C57Bl)F1 mice-hybrids with Lewis lung carcinoma the enhancement of antitumour and antimetastatic effect of the cyclophosphamide is revealed under high-altitude hypoxia influence.     

Accumulation of 125J-triiodothyronine in the transplanted tumors of mice and rats

Investigations carried out in various transplantable tumours (Lewis carcinoma, carcinoma-37, melanoma B-16 in mice and sarcoma-45 in rats) did not show 125J-triiodothyronine accumulation by the tumour.     

Decreased isoproterenol sensitivity of the salivary epithelium in mice with transplanted tumors

The proliferative response of secretory cells of parotid glands to isoproterenol could not be observed in tumour-bearing mice, while in normal mice a ten-fold increase was usually observed. Mice with subcutaneous allografts of normal tissue (tail fragments) demonstrated sensitivity similar to normal mice. Apparently, a lack of sensitivity in tumour-bearing mice is characteristic of the tumour-host interaction. According to electron microscopic cytochemical data the adenylate cyclase activity is not changed in the mentioned cells of the tumour-bearing mice. It is supposed that lack of sensitivity is due to an alteration of certain properties of some other components of the beta-adrenergic system.     

Effects of indomethacin and BCG vaccine on growth of transplanted tumors in mice

Continuous administration of indomethacin (IM) in drinking water (20 micrograms/ml) causes moderate inhibition of the growth of transplantable tumors in control mice but significantly increases the antitumor effect of BCG vaccine inoculated in combination with transplanted tumor cells. Hepatoma 29, insensitive to the vaccine becomes highly sensitivity to it under IM administration.     

Proteolysis in the cells of malignant human and animal tumors

The data concerning proteolytic enzymes in human and animal malignant tumours are reviewed. The activity of these proteinases, its changes in the course of the disease, intracellular localization and secretion into the extracellular space and blood are discussed. The role of proteolytic enzymes including the role of plasminogen activator in tumour progress and during the metastasis development is considered.     

Effect of exogenous interleukin 2 on the functional activity of immunocompetent cells in mice with transplanted tumors

The use of two independent test-systems (intravenous adoptive transfer of immune response on tumour cells by intact syngenic recipient and mixed cultivation of immunocompetent and tumour cells in diffusion chambers) made it possible to establish that exogenous IL-2 possesses an expressive capacity both to the positive and to the negative modulation of immunological mechanisms during the tumour growth.