共查询到18条相似文献,搜索用时 171 毫秒
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以羧甲基壳聚糖(CMCS)和氧化魔芋葡甘聚糖(OKGM)为原料,采用冷冻干燥法制备羧甲基壳聚糖/氧化魔芋葡甘聚糖(CMCS/OKGM)复合海绵,通过FTIR、~1HNMR、SEM等对其结构进行表征,通过吸水率、孔隙率、透气率、对NIH-3T3细胞增殖的影响、抗菌能力及急性全身毒性等测试来评价其性能。确定CMCS/OKGM复合海绵的最优制备工艺为:先采用高碘酸钠氧化制备OKGM,再按5∶5的体积比将质量浓度均为5%的CMCS溶液和OKGM溶液混合,加入2%的甘油作为塑化剂,冷冻干燥即得。CMCS/OKGM复合海绵具有良好的吸水率、孔隙率、透气率、抗菌活性、生物安全性且能促进表皮细胞增殖,是优良的医用慢性伤口敷料基础底料。 相似文献
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以2,4-二羟基苯甲醛(DDBA)为扩链剂,丙烯酸羟乙酯(HEA)为封端剂制备了含有醛基的水性聚氨酯(DPU),在温和的条件下引入不同含量的羧甲基壳聚糖(CMCh)溶液合成了CMCh席夫碱,接着其与丙烯酰胺经自由基反应合成了聚氨酯-羧甲基壳聚糖席夫碱水凝胶(DPU-Ch).通过FTIR、SEM、力学性能、溶胀保水性、抗菌性和血液相容性测试等对水凝胶结构和性能进行了表征.结果表明,水凝胶的机械性能随着CMCh含量的增加先增大后减小,水凝胶显示出良好的溶胀能力和保水能力;水凝胶对革兰氏阳性和阴性细菌菌株均显示出良好的抗菌性能;水凝胶溶血率均低于5%,表明其具有良好的细胞相容性,小鼠成纤维细胞(NIH3T3)存活率在90%以上证明其细胞毒性较低.当CMCh添加量为DPU树脂固含量的4%时,DPU-Ch水凝胶综合性能最佳,溶胀比为10.58,24 h失水率为31.1%,压缩强度为0.70 MPa,溶血率为2.4%,细胞存活率为101%±1.7%,抗菌性能良好. 相似文献
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In order to enhance the mechanical properties of konjac glucomannan film in the dry state and research the application of konjac glucomannan on food preservation domain, blend transparent film was prepared by blending 3 wt % sodium alginate aqueous solution with 4.5 wt % konjac glucomannan aqueous solution and dried at 40oC for 4 h. The structure and properties of the blend films were studied by infrared, wide angle X‐ray diffraction, scanning electron microscopy, and differential thermal analysis. Crystallinities of blend films were increased with the increase of sodium alginate. The tensile strength and breaking elongation of the blend films in dry state were obviously higher than those of both sodium alginate and konjac glucomannan films. Tensile strength of the dry blend film achieved 77.8 MPa when the retention of sodium alginate in the film was 27.9 wt %. The structure analysis indicated that there was a strong interaction between konjac glucomannan and sodium alginate, and this is resulted from the intermolecular hydrogen bonds. Moisture content and degree of water swelling of the blend films were increased due to the introduction of sodium alginate. Results from the film coating preservation experiment to litchi and honey peach showed that this blend film had water‐holding ability. The fruit weight loss rate and rot rate both decreased by various values. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 77: 617–626, 2000 相似文献
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Blend films were prepared by blending 7 wt % konjac glucomannan (KGM) aqueous solution with 2 wt % chitosan (CH) in acetate solution and dried at 40°C for 4 h to obtain the transparent films. Their structure and properties were studied by infrared (IR), wide‐angle X‐ray diffraction (WAXD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and differential thermal analysis (DTA). Crystallinities of the blend films decreased with the increase of konjac glucomannan. The thermostability, tensile strength, and breaking elongation of the blend films in dry state were obviously higher than those of both konjac glucomannan and chitosan films. Tensile strength of the dry blend film achieved 73.0MPa when the weight ratio of chitosan to konjac glucomannan was 7:3. The structure analysis indicated that there is a strong interaction between konjac glucomannan and chitosan resulted from intermolecular hydrogen bonds. The water solubility of the blend films was improved by blending with konjac glucomannan, so they have promising applications to soluble antiseptic coating of pills. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 76: 509–515, 2000 相似文献
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A series of novel blend films of deacetylated konjac glucomannan (d‐KGM) and Chitosan hydrochloride (CHI·HCl) were prepared successfully by using the solvent‐casting technique with different blending ratios of the two polymers. The miscibility and aggregation structure of the blend films were studied by Fourier transform infrared spectroscopy, wide‐angle X‐ray diffraction and scanning electron microscopy. The results indicated that the blend system of d‐KGM and CHI·HCl had a conditional miscibility. A new crystal occurred and hydrogen‐bonding interaction was strengthened when the CHI·HCl content in the blend films was 40%. The effects of deacetylation degree of KGM, acids (the solvent Chitosan dissolved in), temperature, and the mix ratio on the swelling behavior of the blend films were also studied. The blend film KC3 (CHI·HCl content in the blend films was 30%) had not only the highest equilibrium swelling degree (26 times) but also the highest tensile strength, and it could be regarded as a potential absorbent film material. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 相似文献
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Tiziana Nardo Valeria Chiono Piergiorgio Gentile Maryam Tabrizian Gianluca Ciardelli 《国际聚合物材料杂志》2016,65(14):741-750
Poly(DL-lactide-co-ε-caprolactone) (PLCL) and poly(DL-lactide-co-glycolide) (PLGA) blends of various compositions were prepared. Fractured sections of PLCL/PLGA blends did not evidence phase separation and blend glass transition temperatures suggested some degree of blend compatibility. The elastic modulus showed a negative deviation from the additive law of mixture. Superior biocompatibility in terms of fibroblast NIH 3T3 cell adhesion and proliferation, better mechanical properties, and a more homogeneous phase were obtained with PLCL/PLGA 25/75 blend. Rapid degradation of PLCL phase (4–8 weeks) in PLCL/PLGA 25/75 blend led to a porous structure, which makes it a potential candidate for drug delivery systems. 相似文献
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Porous poly(3‐hydroxybutrate‐co‐3‐hydroxyvalerate) (PHBV) film was prepared by solute leaching of salt/PHBV cast film. The surface chemistry of the PHBV membrane was modified by performing graft polymerization of methacrylic acid (MAA) on ozone treated porous PHBV film, followed by immobilization of type I collagen. The surface characteristics of the modified and nonmodified porous films were measured by water contact angle. The rat osteosarcoma cell line UMR‐106 osteoblast like cells were used as model cells to evaluate the cell viability on surfaces. The initial cell attachment, growth pattern, and proliferation as measured by MTT assay were used to evaluate the bone cell viability on the modified and nonmodified films. Among the PHBV films studied, the nonmodified porous PHBV and the porous PHBV film type I collagen dip coated showed no significant difference in cell attachment and proliferation, while the porous PHBV membrane that was collagen immobilized after MAA grafting showed considerable activity of osteoblast like cells. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 1916–1921, 2005 相似文献
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The blend films of konjac glucomannan (KGM) and polyacrylamide (PAAm) were prepared by using the solvent‐casting technique. Transparent blend films were obtained in all blending ratios. The physical properties of the films were investigated by Fourier transform infrared spectroscopy, wide‐angle X‐ray diffraction, thermogravimetric analysis, scanning electron microscopy, and by measurement of mechanical properties. The results indicated the occurrence of intra‐ and intermolecular interactions of the pure components, as well as the intermolecular interactions between KGM and PAAm through hydrogen bond formation. The thermal stability and mechanical properties of both tensile strength and elongation at break of the films were improved by blending KGM with PAAm. It was worth noting that the blend film had the greatest tensile strength when the KGM content in the blend films was around 30 wt %. Surface morphology of the films observed by SEM was consistent with the above‐noted results. Furthermore, the water absorbability of the blend films was also investigated. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 81: 882–888, 2001 相似文献
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A new kind of blend film was made by mixing the solutions of collagen, konjac glucommnnan (KGM), and sodium alginate. The structure of the blend film was characterized by FTIR, XRD, atomic absorption spectrophotometer, and SEM, respectively. The effects of weight ratio between the polymers on light transmittance, tensile strength, elongation at break, water permeability, and water absorption of the film were studied. The results showed that there were strong interactions and good compatibility between collagen, KGM, and sodium alginate in the film. The film possesses good mechanical properties. Therefore, it can be applied in biomedicine as a new type of biomaterial. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007 相似文献
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Poly(ε‐caprolactone) (PCL) has been thermally synthesized, and then fractionated to blend with poly(ethyl glycol) (PEG). Blend films of PCL and PEG have been prepared by solution casting. Fourier transform infrared spectrum and differential scanning calorimetry of the films have been carried out, and the results indicate some hydrogen bonding interaction between the two components, which is resulted from the carbonyl groups of PCL and the hydroxyl end‐groups of the low‐molecular‐weight PEG. Scanning electron microscope images of the blend films reveal porous network structures for their surfaces and for their inner parts and the porous structure becomes more pronounced with the increase of PEG in the blend film. Ibuprofen (IBU) was used as the model drug to test the drug release behavior for the PCL/PEG blend matrices. The results show that IBU could be released from the blend tablets rapidly, and the release rate increases with PEG content. Analysis of the release profiles indicates PCL erosion control release mechanism of pure PCL tablet, but drug diffusion control of the blend tablet, because PEG can absorb water to allow water feasible to diffuse into drug core and dissolve drug. Therefore, the interconnected channels in the blend matrices and the hydrophilic nature of PEG contribute to the improvement of the IBU release rate. The research indicates that drug release rate from PCL based material could be efficiently improved by addition of small amount of hydrophilic low‐molecular‐weight PEG. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011 相似文献