抛落冲击力及其对球磨机筒体结构损伤的分析

湿式球磨机运行时矿石和钢球沿筒体内壁上升,到一定高度而抛落下来,对筒体产生冲击。但在筒体结构强度设计计算中此项冲击力是忽略不计的。根据理论分析和实际观察结果对此项抛落冲击力及其对筒体结构的损伤进行了初步探讨。并认为,必须考虑抛落冲击力对筒体结构强度的影响。最后,提出了防止抛落冲击力对筒体结构损伤的实际措施。     

Modulation of the expression of the rabbit galectin-3 gene by p53 and c-Ha-ras proteins and PMA

Galectin-3 is a galactose-binding lectin that has been found in several mammalian tissues. Galectin-3 gene is expressed in a wide range of normal and tumoral cells. In the case of myeloid cells, its expression correlates with the differentiation of monocytes to macrophages. In the case of cancer cell lines, its expression correlates with tumorigenicity and metastatic potential. The regulation of the expression of this gene is still largely unknown. The rabbit galectin-3 gene has been isolated and characterized. Its structure revealed an organization similar to that of the murine galectin-3 gene. The genomic sequences located upstream from its 5' end, upon insertion upstream from a promoter-free reporter gene, exhibited a strong promoter activity. This activity was upregulated upon treatment of transfected smooth muscle cells with phorbol 12-myristate 13-acetate (PMA) as well as upon transfection with a EJ/ras encoding plasmid. Conversely, it was downmodulated upon transfection with wild-type p53 but not with mutated p53. The regulatory sequences involved in the positive regulation of the gene were located upon serial deletion experiments.     

Briquettes with nanostructured materials used to modify of cast iron

A method is developed to fabricate briquettes with nanostructured materials aimed at modification of cast iron resulting in the improvement of the physicochemical properties of cast iron and its castings. This improvement is achieved by grain refinement, stable modification, the elimination of pyroelectric effect upon modification, and a decrease in the sensitivity to chilling upon melt solidification.     

Joint Committee on Aviation Pathology: XII. Sarcoidosis: a review of some features of importance in aviation medicine

Sarcoidosis is defined in terms of its histology and natural history. Emphasis is placed upon its insidious nature and potentially pronounced pathophysiological effects. The use of lung function studies as an index of disability in the three described phases is discussed. Though we have only found the disease coincidentally in aircraft accidents, stress is placed upon the need for careful monitoring of affected aircrew and the necessity for respiratory function tests.     

Role of behavior genetics in psychology.

Argues that the relevance of behavior genetics to psychology depends upon the extent to which it can alter its fundamental axis from one centering upon genetics to one centering upon behavior. Genetic models make assumptions which in behavior as a class are generally unmet, and at best provide information only about the operations of genes. Rather than a genetics of behaviors, the best use of genotype in behavioral analysis should be sought. This change would produce a behavior genetics perceived as a genetically-aware psychology which concentrates upon mechanisms and allows for the systematic and simultaneous consideration of variables of environmental origin. 3 research strategies appropriate for a genetically-aware psychology are discussed. (47 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

TAR-RNA binding by HIV-1 Tat protein is selectively inhibited by its L-enantiomer

An oligoribonucleotide, corresponding to the Tat-interactive top half of the HIV-1 TAR RNA stem-loop, was synthesized in both the natural D- and the enantiomeric L-configurations. The affinity of Tat for the two RNAs, assessed by competition binding experiments, was found to be identical and is reduced 10-fold for both, upon replacement of the critical bulge residue U23 with cytidine. It is suggested that this interaction of the flexible Tat protein depends strongly upon the tertiary structure of a binding pocket within TAR, but not upon its handedness, and may be described by a 'hand-in-mitten' model.     

Health care systems in transition: People's Republic of China. Part I: An overview of China's health care system

The People's Republic of China for the first 30 years of its existence had a centrally directed health care system which achieved impressive health gains for its population. By emphasizing prevention; organizing innovative, low-cost, locally controlled health services; and promoting accessible primary health care in rural areas, China increased life expectancy for most of its people, dramatically reduced levels of infant mortality, and eradicated or controlled a range of infectious and parasitic diseases. Since 1978, however, China's leadership has come to depend more upon market forces than central direction and planning to achieve economic growth. These new orientation has had major effects upon the organization and financing of health services. After more than a decade of economic and agricultural reform, China still has problems providing good-quality, affordable, and equitable health services for the majority of the rural population and both urban and rural poor. The need to pay for health care considerably exacerbates poverty in China. This paper describes the structure of government and the health care system, the nature of change during 1978-90, the impact of the reforms upon health status and health care delivery, and future challenges.     

Clinico-radiologic and morphopathologic aspects of mediastinal-pulmonary hemangiopericytoma

The paper points out the diagnosis of intrathoracic hemangiopericytoma in 13 patients in the "M.Nasta" Institute of Pneumophthisiology, a seldom seen disease considered quite serious because of its malignant form and its late finding out. This is due to its non-distinctive, small number of symptoms, which has a negative influence upon the disease prognosis and evolution.     

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

Dehydration of proteins results in significant, measurable conformational changes as observed using Fourier-transform infrared spectroscopy and resolution-enhancement techniques. For several proteins these conformational changes are at least partially irreversible, since, upon rehydration, denaturation and aggregation are observed. The presence of certain stabilizers inhibited these dehydration-induced transitions; the native structure was preserved in the dried state and upon reconstitution. Conformational transitions were also observed in a model polypeptide, poly-L-lysine, after lyophilization and were inhibited with the addition of stabilizing cosolutes. The ability of a particular additive to preserve the aqueous structure of dehydrated proteins and poly-L-lysine upon dehydration correlates directly with its ability to preserve the activity of lactate dehydrogenase, a labile enzyme, during drying.     

Thermodynamics of BPTI folding

A calorimetric study of the basic pancreatic trypsin inhibitor (BPTI) has been performed using the new generation of the adiabatic scanning microcalorimeters, operating in an extended temperature range of 5-130 degrees C. Precise measurements of the heat capacities of the native and unfolded states of BPTI show that the heat capacity change upon unfolding strongly depends on temperature; its value is maximal at about 50 degrees C and diminishes as the temperature is increased. The temperature dependencies of the enthalpy and entropy changes upon BPTI unfolding were found to be similar to those normally observed for other small globular proteins. The stability of BPTI has been correlated with its structure.     

不凝性气体对母液蒸发的影响与排除方法

本文叙述了母液蒸发过程中不凝性气体的来源及其对蒸汽温度、传热系数和传热面积的影响,阐明了排除不凝性气体的重要性,介绍了不凝性气体的常用排除方法。     

Importance of the critical-size bone defect in testing bone-regenerating materials

MOTIVATION: When two or more genomic maps of a chromosomal region are available, it is useful to be able to synthesize them to create a merged map. RESULTS: We show that map merging is an exploratory process because there are multiple ways to combine data based upon what the user wishes to focus on, and upon which particular data subset emphasis is desired. We describe Mapmerge, a program for merging two genomic maps, discuss its limitations, and illustrate an example of its use. AVAILABILITY: Freely available (ANSI C source code, a Make file, test data files, documentation) on request from the author. CONTACT: Prakash.Nadkarni@yale.edu     

冷轧冲压用汽车薄钢板的发展

介绍了三代冷轧冲压用汽车薄钢板的发展情况，着重叙述了第二代产品的特点以及国内冷轧深冲汽车板与国外同类产品的差距，为微碳深冲汽车板的研制提供了依据。     

Kinematic viscosity of Mg-Al melts in the magnesium-rich portion

Kinematic viscosity ν of Mg-Al melts containing up to 14 at % second component is measured by the method of damped torsional vibrations of a crucible with a melt. The measurements are performed in the temperature t range between liquidus and 900°C upon heating of a sample after its melting and upon subsequent cooling. Kinematic viscosity isotherms and the concentration dependences of the activation energy of viscous flow are constructed.     

Specializations in the predatory behavior of grasshopper mice (Onychomys leucogaster and O. torridus): A comparison with the golden hamster (Mesocricetus auratus).

The purpose of this study is to show that the grasshopper mouse's attack upon insects represents a specialized response that is well-suited for capturing nocturnally active arthropods, even ones with formidable defenses. Basically, a comparative approach is used. In the first part, the aspects of the biology and social behavior of the grasshopper mouse are compared with those of the omnivorous golden hamster to show that the former exhibits more specializations for a carnivorous life-style than the latter. Next, certain details of the motor, sensory, decision-making, and developmental processes of the attack upon insects are compared between grasshopper mice and hamsters. Grasshopper mice exhibit a more specialized method of seizing a moving prey, have a better suited sensory basis for tracking moving prey in the dark, and exhibit a more canalized decision-making and developmental process than hamsters. The significance of these differences to the mouse's carnivorous life-style are discussed. Finally, the grasshopper mouse's attack upon insects is compared with its attack upon lab mice to show that the former attack represents a different and more canalized response than the latter and that the attack upon insects plays a central role in the mouse's carnivorous life-style. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The binding and utilization of hemoglobin by Prevotella intermedia

Personalism in ethics denotes any system based upon the value of the person. Several versions of personalist morals have been developed over the past 50 years. Some have had particular interest in the field of medical ethics. Here the question is being studied about one such system, the so-called Leuven personalist morals and its usefulness in today's world of bioethics. In order to test the usefulness of this system the case of artificial insemination is examined both in the early 1970s in the context of the Leuven clinics and, subsequently, in the 1990s in a US policy document. The investigation reveals strengths and weaknesses of this personalism. Regarding AID it reveals unresolved oppositions. The conclusion seems to be that this personalism had, no doubt, a profound impact upon medical ethics within its own circle but, as regards the universal usefulness of the system, serious doubts remain.     

谈科技统计核算问题及措施

针对广钢科技统计核算的现状和存在的问题进行了分析,并提出了改进科技统计工作应采取的措施。     

Reduction kinetics of molybdenum oxide in slag

The reduction rate of Mo oxide in slag by iron-carbon melt under different stirring conditions, reaction temperatures and slag composition has been investigated. Results indicate that the reduction of Mo oxide is a fast reaction; both stirring and temperature have evident influence upon the reaction; while the initial concentration of Mo oxide and content of fluoride in slag have also some influence upon the reaction. The reduction of Mo oxide is an apparent first order reaction. At 1440–1500°C, the reduction rate of Mo oxide is mainly controlled by Mo transfer in slag, with its diffusion activation energy of 223 kJ/mol. At 1500–1590°C, the transfer of Mo in metal turns to be the main limiting step, with its diffusion activation energy of 81.5 kJ/mol.     

On Private Practice.

Comments upon David Shakow's article "Seventeen Years Later" (see record 1965-13316-001) which offers a scholarly review and informed opinion on the multifaceted challenge of training. Shakow holds an interesting view that private practice is an escape holds validity to some extent. So also does its obverse: Institutional practice is an escape (from full independence?). The author of this comment discusses Shakow's view and provides additional information concerning private practice and the market atmosphere that influences it. He feels that private practice should not be summarily dismissed from training conferences nor be poorly represented, but should be called upon for its full contribution to training. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) disrupts social memory/recognition processes in the male mouse

Male mice treated with MPTP or vehicle were tested for their ability to demonstrate a memory-recognition response as evaluated in a habituation-dishabituation task. Treatment with MPTP severely disrupted the male's habituation-dishabituation response profile compared to vehicle treated animals. Administration of L-DOPA at 45 min prior to behavioral testing in MPTP animals restored their performance on the habituation-dishabituation test to levels observed in vehicle treated animals. There was also a tendency for L-DOPA to produce enhanced responsiveness in vehicle treated animals. Mice treated with MPTP had significantly reduced concentrations of norepinephrine within the olfactory bulb and hippocampus. Vehicle treated mice administered L-DOPA had significantly increased dopamine concentrations within the corpus striatum. These results suggest that, in addition to its putative effects upon the nigrostriatal dopaminergic system and motor behavior, MPTP is also exerting substantial effects upon other systems. In particular, the noradrenergic system and its potential involvement with memory/recognition processes in the CD-1 mouse appears to be very sensitive to the neurotoxic effects of MPTP.