LiNbO3光波导紫外表面等离子共振传感器模拟计算

高折射率的LiNbO3光波导,构成四层高折射率波导表面等离子共振传感器.采用传输矩阵方法得基模TM模色散表达式,研究了光波导有效折射与样品折射率之间的关系、光波导传输常数和波长的关系,由表面等离子体波共振耦合条件,得到不同样品折射率的表面等离子共振波长.利用菲涅耳的反射率公式,计算了四层结构波导传感器的透射谱,得到表面...     

光纤表面等离子体波传感器测量液体折射率的研究

针对表面等离子体波共振现象产生的原理和激发条件进行了阐述.通过自行设计的一套光纤表面离子体波传感器测试系统,测定了从0%～70%的不同浓度甘油水溶液折射率与共振波长的关系,实验结果具有较好的重复性并和理论分析相吻合.由此得到一种基于光纤SPR传感技术的液体折射率测量方法.     

表面等离子体共振生物传感器的研究现状

表面等离子体共振生物传感器是分子生物学与光学、电化学、微电子学等相结合的产物,是分子生物学信息分析检测最重要的技术之一。本文简要介绍了表面等离子体共振生物传感器的结构原理及研究方向。     

赤潮毒素大田软海绵酸表面等离子共振免疫检测方法研究

结合表面等离子体共振技术与免疫检测技术,研究和建立了一种响应速度快、免标记、低成本新型海洋赤潮毒素大田软海绵酸检测方法.基于SpreetaTM传感器构建了小型表面等离子共振免疫检测系统,采用共价偶联方法在传感器金膜表面修饰大田软海绵酸-牛血清蛋白抗原作为生物敏感膜;测得该方法相对标准偏差为1.51％ (n=12),定量...     

光纤表面等离子体共振传感器研究进展

以光纤传输技术的表面等离子体共振技术有机结合的光纤表面等离子体共振传感器，是实现微量生物和化学活性物质定量测定的重要技术之一。介绍了表面等离子体共振的基本原理，表面等离子体共振光纤传感器的制作及应用的研究进展。     

SPR传感芯片的理论与实验研究

针对光纤SPR(表面等离子体共振)传感器制作工艺复杂的问题,提出了一种光纤先固定后部分镀膜的SPR传感芯片的制作方法.依据电磁场和射线理论,分析并讨论了此种波长调制部分镀膜SPR传感芯片的工作原理,采用MEMS制作工艺对探测光纤进行封装固定以后,再对光纤进行部分镀膜,其结构简单,工艺性好,易于实现批量化.最后,搭建了一套基、于波长检测的光纤SPR测试系统对其进行测试.实验结果表明:在折射率范围为1.33～1.36时,共振波长同折射率具有良好的线性关系,光谱仪分辨率为0.1 m时,其分辨率可达到3×10-5折射率单位.     

基于VO2的超表面双气体传感器设计

针对传统矿用气体传感器易受温度和环境湿度等因素的影响而导致稳定性不高的问题,基于局域表面等离子共振原理和二氧化钒(VO₂)的相变特性,设计了一种基于VO₂的超表面双气体传感器。该传感器结构由上下三层组成,表面由多层金属-介电-金属(MDM)结构组成。根据VO₂的相变特点,通过改变施加的偏置电压,以电阻加热的形式加热金属板,精细控制VO₂的温度,通过改变VO₂的电导率来模拟VO₂的不同状态。当VO₂呈高温金属态时,上三层形成MDM结构,VO₂表现出金属性质,并在1 721.3 nm激发局域表面等离子体共振(LSPR),实现甲烷检测,传感器的吸收率为94.3%,甲烷灵敏度为4.21 nm/%。当VO₂呈低温绝缘态时,下三层形成MDM结构,在2 694.6 nm激发LSPR,实现氢气检测,传感器的吸收率为95.9%,氢气灵敏度为2.10 nm/%。当环境折射率发生变化时,VO₂     

基于小波分析的SPR传感器信号处理

介绍表面等离子共振(SPR)的基本原理,以及基于该原理的传感器试验设备和原理,将采集到的信号用正交紧支集小波Daubechies小波等方法进行处理,使设备对液体浓度的分辨率提高两个数量级,可满足较高精度测量的要求.     

抗共振反射集成光学传感器的研究进展

抗共振反射光波导(ARROW)具有与传统光波导所不同的传播特性。利用覆盖层的抗共振反射性质,ARROW传播单模、高阶模被泄漏到基体。基于折射率的变化,抗共振反射传感器对物理量、化学量和生物分子间的相互作用有很高的敏感性。介绍了ARROW的结构、传感器的工作原理以及最新研究进展。由于可采用CMOS工艺制作波导,且能与光探测器在一块集成,抗共振反射传感器将具有广阔的应用前景。     

有害气体检测的光纤传感技术发展

光纤气体传感器具有易于小型化、可遥测、灵敏度高、响应快等诸多优点.根据传感原理,概述了有害气体检测的光纤传感器,包括折射率变化型光纤气体传感器、倏逝波光纤气体传感器、表面等离子共振光纤气体传感器、光声光纤气体传感器、多孔光纤气体传感器,以及吸收型光纤气体传感器、荧光型光纤气体传感器、染料指示剂型光纤气体传感器.简要介绍了光纤气体传感器的发展.     

光纤表面等离子体波传感器中共振波长的理论计算

光纤SPR传感器是一种新型传感器,可在多个领域实现远距离实时在线监测.根据表面等离子体波的共振条件计算了光纤SPR传感器的关键参数--共振波长,并且给出在一定条件下传感器的最大量程.为光纤SPR传感器的设计提供了有力的工具.     

动态范围可调的波导型SPR传感器模型

表面等离子体共振 (SPR)技术是一种简单直接的传感技术 ,SPR对金属表面附近的折射率的变化极为敏感 ,利用这一性质 ,表面等离子体共振传感器已成为生物传感器研究领域的热点。现提出一种电光调制波导型SPR模型 ,模拟计算表明该模型在不损害灵敏度的条件下 ,扩大了探测的动态范围。     

Sensitivity Comparison of Surface Plasmon Resonance and Plasmon-Waveguide Resonance Biosensors

Plasmon-waveguide resonance (PWR) sensors are particularly useful for the investigation of biomolecular interactions with or within lipid bilayer membranes. Many studies demonstrated their ability to provide unique qualitative information, but the evaluation of their sensitivity as compared to other surface plasmon resonance (SPR) sensors has not been broadly investigated. We report here a comprehensive sensitivity comparison of SPR and PWR biosensors for the p-polarized light component. The sensitivity of five different biosensor designs to changes in refractive index, thickness and mass are determined and discussed. Although numerical simulations show an increase of the electric field intensity by 30-35% and the penetration depth by four times in PWR, the waveguide-based method is 0.5-8-fold less sensitive than conventional SPR in all considered analytical parameters. The experimental results also suggest that the increase in the penetration depth in PWR is made at the expense of the surface sensitivity. The physical and structural reasons for PWR sensor limitations are discussed and a general viewpoint for designing more efficient SPR sensors based on dielectric slab waveguides is provided.     

Manufacture of robust surface plasmon resonance fiber optic based dip-probes

Surface plasmon resonance (SPR) spectroscopy has been conducted on both prism and fiber optic (FO) based sensors for several years. This technique measures the refractive index (RI) of a solution or layer adsorbed to a thin (50 nm) Au layer on the sensor substrate. To date a succinct set of protocols have not been published regarding the optimization of fiber-based SPR dip-probe sensors. Such sensors would allow application of SPR to a wider variety of applications. This paper focuses on consideration of the choice of fiber, isolation of the mirror from the sensing area, and orientation of the probes in the metal layer sputter deposition chamber in the manufacture of SPR dip-probes for reproducibility and robustness. Optimization of the process yields sensors with a batch to batch reproducibility as low as 0.5 nm in the location of the SPR spectral minima. Further study of RI measurements by the same probe over 2 months show these SPR dip-probes have a long shelf-life. A selection of probes was exposed to various solutions to monitor their drift. The data shows the probes’ response indicated a lowering of the RI measured over a period of 3 or 7 days depending on the probe type. Evidence of surface porosity and damage upon exposure to hydrothermal water seems to indicate these sensors are prone to chemical attack. Further research is needed to characterize this attack and allow creation of more robust sensors.     

Diffractive optical coupling element for surface plasmon resonance sensors

Design, technological features, and performance of polymeric diffractive optical coupling elements (DOCEs), developed for surface plasmon resonance (SPR) sensors are reported. The concept is based on input and output coupling of collimated and perpendicularly incident light beams to exchangeable SPR sensor chips. In the SPR sensor chips, one DOCE couples the input light beam to a (bio-)chemical sensor surface and another DOCE images the output light beam onto a detector array. The manufacturing technique is based on an injection moulding process similarly to the manufacturing process of compact discs allowing precision manufacturing and reproduction of the grating topography of the DOCEs. The DOCE-based SPR sensor chip is specifically suitable for miniaturisation and large scale production, while maintaining high optical quality and performance.     

Selectivity of SPR fiber sensors in absorptive media: An experimental evaluation

Conventional surface plasmon resonance (SPR) fiber sensors show selective behavior when resonance wavelengths are tuned to absorption peaks of the surrounding medium, as it is experimentally shown and evaluated in this paper by using a doubly-deposited uniform-waist tapered optical fiber (DLUWT) and a dye as a test material. This behavior is clearly distinguishable from the usual response to nonabsorbing media and can be used to develop a new concept of SPR transducers. At the same time, the obtained results, which are in accordance with the theoretical predictions permit to increase the basic knowledge on surface plasma waves excitation in optical fibers.     

Sensor properties and surface characterization of the metal-deposited SPR optical fiber sensors with Au,Ag, Cu,and Al

Metal-deposited optical fiber sensors with Cu and Al with a film thickness of 45 nm based on surface plasmon resonance (SPR) were fabricated for the first time. The response curves and the properties of these sensors were investigated with a comparison of those of the sensors with Au and Ag. The reflection properties of thin films of Au, Ag, Cu, and Al due to the SPR phenomenon were also measured and considered. The metal-deposited SPR optical fiber sensors with Au, Ag, and Cu have high sensitivities and good responses. Though the sensor with Al shows a lower sensitivity, it has a wider response range in the refractivity. The response curve of the sensor with Au calculated from SPR theoretical equations agreed well with that obtained by the experiment. However, the response curves of the sensors with Ag, Cu, and Al have the effects of the surface oxide layers. The surface characterization of these metal films by X-ray photoelectron spectroscopy (XPS) showed the presence of oxide layers on the films of Ag, Cu, and Al. A very thin (about 0.3 nm) oxide layer is present on Ag, while thick (about 2 nm) oxide layers are present on Cu and Al.     

Molecularly imprinted ligand-exchange recognition assay of DNA by SPR system using guanosine and guanine recognition sites of DNA

Molecular imprinting polymer (MIP) as a recognition element for sensors are increasingly of interest and MIP-SPR have started to appear in the literature. In this study, we have proposed a novel surface imprinting method for DNA recognition and determination by methacryl-amidohistidine-platinum(II) [MAH-Pt(II)] as a new metal-chelating monomer via metal coordination–chelation interactions and guanosine/guanine templates of DNA. The study includes the measurement of binding interaction of molecular imprinted surface plasmon resonance (SPR) sensor via ligand interaction and recognition selectivity studies of guanosine and guanine imprinted polymers with respect to guanine and dsDNA. Adsorption isotherms of adenosine, guanosine, guanine, adenine, ssDNA and dsDNA were plotted and affinity constants for guanosine and guanine imprinted films were also calculated.