共查询到20条相似文献,搜索用时 125 毫秒
1.
2.
3.
4.
5.
6.
吲哚及其衍生物具有非常重要的生物和药理活性,广泛应用于农业、医药等领域中。因此对吲哚及其衍生物合成方法的研究也越来越多。近年来经过化学家的努力,以2-炔基芳香胺分子内环化和芳香胺类化合物与炔反应来合成吲哚衍生物都取得了很大的进展,成为了重要的合成方法。主要对近十年来这两类方法即2-炔基芳香胺在各种不同催化条件下的分子内环化和各种不同取代的芳香胺类化合物与炔反应合成吲哚衍生物的研究进展进行了综述。 相似文献
7.
8.
徐兆瑜 《精细化工原料及中间体》2009,(1)
介绍了吲哚及十几种吲哚化合物的性质、合成方法以及在医药领域中的应用简况,这些吲哚衍生物如:3-醛基吲哚-5-甲酸乙酯,5-甲氧基吲哚,3,3,-二吲哚甲烷(DIM)等。许多吲哚及其衍生物在治疗癌症.艾滋病、心血管疾病以及骨风湿性疾病、消炎、镇痛等医药治疗方面取得了显著成就,故对其相关化合物作了重点叙述。例如:MCM-41负载Lewis酸催化合成2-甲基吲哚,5-甲氧基吲哚,吲哚甲基海英的合成等。已经表明,吲哚及其衍生物在医药化工领域中的应用具有很好的前景,值得引起关注和进-步研究和开发。 相似文献
9.
徐兆瑜 《精细化工原料及中间体》2008,(12)
介绍了吲哚及十几种吲哚化合物的性质、合成方法以及在医药领域中的应用简况,这些吲哚衍生物如:3-醛基吲哚-5-甲酸乙酯,5-甲氧基吲哚,3,3,-二吲哚甲烷(DIM)等。许多吲哚及其衍生物在治疗癌症,艾滋病、心血管疾病以及骨风湿性疾病、消炎、镇痛等医药治疗方面取得了显著成就,故对其相关化合物作了重点叙述。例如:MCM-41负载Lewis酸催化合成2-甲基吲哚,5-甲氧基吲哚,吲哚甲基海英的合成等。已经表明,吲哚及其衍生物在医药化工领域中的应用具有很好的前景,值得引起关注和进一步研究和开发。 相似文献
10.
11.
Laurent Djakovitch Vronique Dufaud Rabah Zaidi 《Advanced Synthesis \u0026amp; Catalysis》2006,348(6):715-724
Heterogeneous palladium catalysts ([Pd(NH3)4]2+/NaY and [Pd]/SBA‐15) were applied to the synthesis of 2‐functionalised indoles, giving generally high conversions and selectivities (>89% yield) using only 1 mol % [Pd]‐catalyst under standard reaction conditions (polar solvent, 80 °C). For the synthesis of 2,3‐functionalised indoles by cross‐coupling arylation, the [Pd]/SBA‐15 catalyst was found to be particularly interesting, producing the expected compound with =35% yield after 12 days of reaction, which is comparable to the homogeneous catalyst, Pd(OAc)2 (=48% yield). In the course of the study, the dual reactivity of the indole nucleus was demonstrated: aryl bromides gave clean C C coupling while aryl iodides led to a clean C N coupling. 相似文献
12.
A novel heterogeneous palladium (Pd) nanoparticle catalyst stabilized by collagen fibers (CF) was synthesized. Epigallocatechin-3-gallate (EGCG), a typical natural polyphenol, was grafted onto the CF surface to improve the stabilization and immobilization of Pd(0) nanoparticles. The main physical and chemical properties of the catalyst were characterized by means of Scanning Electron Microscopy, Fourier Transform-Infrared Spectroscopy, X-ray Photoelectron Spectroscopy, X-ray Diffraction and Transmission Electron Microscopy. This catalyst is in an ordered fibrous state with high flexibility. The Pd(0) nanoparticles with diameters of 3–4 nm are homogeneously dispersed onto the outer surfaces of CF, and they are stabilized by the coordinative interactions between the surface Pd atoms of nanoparticle and the surrounding oxygen and nitrogen atoms of the EGCG-grafted CF. These stabilized Pd(0) nanoparticles were found to be active and selective catalysts for nitrobenzene and its derivatives, directly hydrogenating to the correspondingly reductive anilines under mild conditions. Both Pd particle size and activity of the catalyst showed a marked dependence on the grafting degree of EGCG on CF. These catalysts can be easily recovered, reused multiple times, and stored for two months in air while maintaining high catalytic efficiencies. All these facts suggest that the EGCG-grafted CF can be used as an effective stabilizer for the preparation of Pd(0) nanoparticle catalysts. 相似文献
13.
Nabin K. Nag 《Catalysis Letters》1994,24(1-2):37-46
Electron spectroscopy for chemical analysis (ESCA) and carbon monoxide adsorption techniques have been applied to study the percent exposed (i.e., dispersion) and Pd deposition in the pores of highly porous gamma alumina-supported Pd catalysts. A correlation has been found between Pd dispersion and its extent of penetration into the pores: more edge-coated catalysts are less dispersed. The dispersion of Pd is controlled by a carrier-catalyst interaction that originates in part from electron transfer from the support to the supported Pd. This electronic interaction is demonstrated by the broadening of the ESCA peaks. The activity of the catalysts, measured by the hydrogenation of nitrobenzene to aniline, is dependent on the dispersion of palladium. 相似文献
14.
15.
16.
Patricia Taladriz-Blanco Pablo Hervés Jorge Pérez-Juste 《Topics in Catalysis》2013,56(13-14):1154-1170
We intent to present an overview of the available catalysts for the carbon–carbon cross-coupling reactions based on supported palladium (Pd) nanoparticles (NPs). We begin this perspective with a brief introduction about the cross-coupling reactions and the mechanistic implications of using Pd NPs as catalyst, i.e. heterogeneous versus homogeneous catalysis, then we summarize some of the most versatile Pd supported catalysts as a function of its nature. The supported catalysts have been classified in inorganic, organic and hybrid supports. Finally we outline the perspectives for the development of new Pd supported catalysts. 相似文献
17.
Hayato Sakai Ken Tsutsumi Tsumoru Morimoto Kiyomi Kakiuchi 《Advanced Synthesis \u0026amp; Catalysis》2008,350(16):2498-2502
One‐pot, four‐step syntheses of indoles using both solid‐supported heterogeneous and homogeneous palladium catalysts and reagents were carried out. Such a combination of these two‐phase catalysts and reagents causes a dramatic increase in yield, and it is a simple process. The presented methodology is effective for four‐step reactions to provide various functionalized indoles. 相似文献
18.
1 INTRODUCTION
Catalytic hydrodechlorination is an elegant reaction for disposal of environmentally hazardous chlorocarbons,such as chloro-benzene[1].Development of a new catalyst with excellent stability is necessary due to the deactivation of supported noble metal catalysts[1].However the modification of catalytic properties of catalysts in hydrodechlorination reaction by introducing stable ligands to noble metals has been the least studied.Here the synthesis of Pd(Ⅱ) 2,9,16,23-symetrically tetrasubstituted phthalocyanines PdPTX4 (where X=-H,-NO2,-NH2 respectively) from phthalimide derivatives is reported,and their application as catalysts in hydrodechlorination of chlorobenzene,which is a representative environmentally hazardous materials is discussed. 相似文献
19.
Tungsten–palladium selective hydrogenation catalysts 总被引:1,自引:0,他引:1
Steady-state, steam-reforming rates for methane were measured on model and high-surface-area, ceria-supported Pd catalysts
and compared to rates on Pd/silica between 600 and 825 K. Specific rates on Pd/ceria were higher than those on Pd/silica by
a factor of 10 5 and were higher even than rates reported in the literature for Ni catalysts. Model catalysts prepared with Pt or Rh on ceria
also showed very high rates, essentially identical to rates for Pd/ceria. However, catalysts prepared by addition of Pd to
ceria which had been calcined to high temperatures (>1175 K) before the addition of Pd were not active. Based on these results,
we suggest that steam reforming on ceria-supported catalysts occurs through a bifunctional mechanism in which oxygen from
ceria reacts with dissociated methane on the precious metal. High-temperature calcination of ceria significantly changes its
reducibility, so that the reaction is not enhanced.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
20.
在六苄基六氮杂异伍兹烷(HBIW)的催化氢解反应中,所用催化剂是Pd(OH)2/C,而Pd属于贵金属,它的回收利用直接影响着最终产品的成本核算。对HB研的催化氢解反应中产生的废催化剂进行了回收,并将回收所得金属钯重新制备成催化剂。再次用于HBIW的催化氢解反应,其活性与以PdCl2为前体制备的催化剂活性相当。回收的金属钯纯度为99.6%,回收率为92%-94%。 相似文献