Lifetime exercise and disk degeneration: an MRI study of monozygotic twins

Participation in some competitive sports has been shown to increase disk degeneration; however, the long-term effects of recreational physical activities are unclear. We investigated the effects of endurance exercise and power sports on disk degeneration in monozygotic male twins with contrasting lifetime exercise histories. The effects of endurance exercise were studied in 22 discordant twin pairs (mean lifetime frequencies of 3.9 vs 1.1 times/wk), and the effects of power sports were investigated in 12 discordant pairs (2,300 vs 200 h of weightlifting). The age range of the twins was from 35 to 69 yr. No differences in MRI findings between co-twins discordant for endurance exercise were found at any of the spinal regions. Subjects with more power sport involvement had greater disk degeneration in the T6-T12 region (P < 0.03), but similar findings were not present in the lumbar spine. Controlling for recalled back injuries, occupational loading, smoking, and driving did not significantly affect the results. No signs of beneficial or harmful effects of lifetime endurance exercise on disk degeneration were seen. Increased power sport participation was associated with slightly greater disk degeneration in the lower thoracic spine, but not in the lumbar spine.     

Phylogenetic studies of complete mitochondrial DNA molecules place cartilaginous fishes within the tree of bony fishes

PURPOSE: A major research priority is the influence of childhood and adolescent physical activity patterns on adult physical activity. The research in this area is inconsistent. Therefore, the purpose of this study was to evaluate the relationships among specific components of physical activity during childhood and adolescence and exercise habits in adulthood. METHODS: We analyzed preteen and teenage experiences, individual and team sports, and several psychosocial variables. One hundred and five male volunteers completed questionnaires about their current (estimated energy expenditure (EE)) and historic physical activity and a treadmill stress test. RESULTS: Based on correlations and regression analyses, without and with controlling for potentially confounding variables (treadmill run time and sum of skinfolds), the frequency of being forced to exercise and the frequency of being encouraged to exercise during the preteen years were inversely related to adult physical activity. Being forced to exercise during the preteen years was more related to participation in individual sports than to participation in team sports or both individual and team sports. CONCLUSIONS: Being forced to exercise during childhood may have potentially negative consequences for later activity. The findings indicate that experiences related to participation in activity during childhood and adolescence may influence adult physical activity. The implications of our findings are discussed and future research is recommended.     

Serum lipid physiology and the influence of glaucoma medications

BACKGROUND: Regular physical exercise is not a widespread habit among the population. Early childhood in a crucial stage for acquiring this habit. The objective of this study was that of ascertaining the behavior of school-age children with regard to the degree of physical activity they do and to examine the factors involved. METHODS: An observational study was conducted by means of a survey based on a questionnaire which 6th and 8th grade students in a Basic Health Care District of Cordoba (N-585) filled out on their own. Questions were asked regarding the frequency of exercise, preferences and prospects for practicing sports, the children's physical shape and school physical education classes, in addition to other behavior comprising their lifestyles. A dual-variable (p .05) and a multiple-variable analysis was conducted employing logistic regression. RESULTS: A total of 548 students filled out the survey (response rate = 97.8%). 79.3% (IC95% 75.7-82.6) were involved in extracurricular physical activities, 21.0% (IC95% 17.1-24.7%) being involved in intense physical exercise. 50.5% (IC95% 46.3-54.8) did not think that they were in good physical shape. The age, sex, type of residence, the involvement in sports on the part of their parents or a close friend and what they considered their degree of healthiness to be comprised the variables quite strongly linked to doing exercise (p .001). CONCLUSIONS: The prevalence of physical exercise is high, although it progressively decreased with age, especially for girls. A major number of students considered themselves to be in unsatisfactory physical condition.     

The effect of lifelong exercise on psychomotor reaction time: a study of 38 pairs of male monozygotic twins

PURPOSE: The aim was to study the effect of lifetime physical activity on psychomotor speed. METHODS: Foot and dominant hand visual simple and choice psychomotor reaction times were studied among monozygotic twins (38 pairs) aged 35-69, discordant for lifetime exercise histories. RESULTS: There was a trend that some components of psychomotor reaction time were faster for frequent than for occasional exercisers, but the findings were not consistent for the hand and feet. After controlling for occupational physical activity, only choice decision time for the hand (26 ms, P < 0.01) and choice reaction time for the contralateral foot (51 ms, P < 0.05) both remained 7% faster. There was no trend for systematic differences in reaction times between twins engaged in regular exercise versus their siblings exercising infrequently. CONCLUSIONS: Results suggest a somewhat smaller effect of exercise than reported in previous studies. Reaction time may be significantly affected only by vigorous, frequent exercise. Thus, health promotion through exercise may be unlikely to have notable effects on reaction time.     

Relationships between bone mass measurements and lifetime physical activity in a Swedish population

Lifetime occupational and leisure time activities were assessed by a questionnaire in order to evaluate their relationship to bone mass measurements and biochemical markers of bone metabolism in a population of 61 women and 61 men, randomly selected from a Swedish population register, to represent ages between 22 and 85 years. We also considered possible confounders by using questions about smoking habits, milk consumption, hormone replacement therapy (HRT), and menopausal age. Bone mineral density (BMD) and bone mineral content (bone mass, BMC) of the total body, lumbar spine, and proximal femur (neck, trochanter, Ward's triangle) were measured by dual energy X-ray absorptiometry (DXA), and BMD of the forearm with single energy X-ray absorptiometry (SXA). In addition, both DXA and SXA provided information on bone area. Quantitative ultrasound measurements (QUS) at the heel were performed to assess the speed of sound (SOS) and broadband ultrasound attenuation (BUA). Fasting blood samples were analyzed for biochemical markers of bone metabolism as well as parathyroid hormone (PTH) and total serum calcium. After adjustment for confounding factors, neither BMD nor QUS measurements were consistently related to lifetime leisure time or occupational activities; nor were there any consistent patterns relating biochemical markers of bone metabolism to bone mass measurements. However, physical activity seemed to influence bone mass, area, and width more than density. In men, high levels of leisure time activity were associated with raised values for lumbar spine area (6.2%) and width (3.3%) as well as for femoral neck area (5.5%) compared with their low activity counterpart. Men exposed to high levels of occupational activity demonstrated lower lumbar spine BMD (10.9%) and area (5.3%) than men with low activity levels. Within an unselected Swedish population, estimation of lifetime occupational and sport activities as well as bedrest, using a questionnaire, demonstrated no major effects on bone density. However, the association between high levels of lifetime activity and raised values for bone mass, area, and width indicate that geometrical changes in bone may provide better estimations of mechanically induced bone strength than bone density, at least in men.     

Leisure and occupational physical activity and risk of colorectal adenomatous polyps

Multiple studies have shown a protective effect for physical activity on the incidence of colorectal cancer, but few have addressed its association with incident adenomas and none have investigated its association with metachronous adenomas. We interviewed 2,001 patients undergoing colonoscopy in 3 New York City practices between 1986-1988. Of these, 298 had a first diagnosis of adenomas, 506 had normal colonoscopies, 197 had metachronous adenomas and 345 had normal colonoscopies with a past history of adenomas. Subjects were queried regarding use of moderate amounts of recreational exercise (swimming, jogging, biking, racket sports and other sports) on a regular basis, and were also asked to estimate their level of physical activity. Occupational physical activity was assessed through a blinded coding of occupational titles. After adjusting for age, years of education, body mass index, total caloric intake, dietary fiber intake, dietary fat intake and years of cigarette smoking, protective effects of borderline significance were observed among males for leisure physical activity for metachronous and incident cases. Occupational physical activity was found to be significantly protective in male incident cases. Men with increased levels of either occupational or leisure activity showed a reduction for incident and metachronous cases. No effects were observed for females. Thus, in this study, both leisure and occupational physical activity were associated with a reduced risk of incident and metachronous adenomas among men but not women.     

Parent–child attitude congruence on type and intensity of physical activity: Testing multiple mediators of sedentary behavior in older children.

Objective: This study examined parent–child attitudes on value of specific types and intensities of physical activity, which may explain gender differences in child activity, and evaluated physical activity as a mechanism to reduce time spent in sedentary behaviors. Design: A community sample of 681 parents and 433 children (mean age 9.9 years) reported attitudes on importance of vigorous and moderate intensity team and individually performed sports/activities, as well as household chores. Separate structural models (LISREL 8.7) for girls and boys tested whether parental attitudes were related to child TV and computer via child attitudes, sport team participation, and physical activity, controlling for demographic factors. Main Outcome Measures: Child 7-day physical activity, sport teams, weekly TV, computer. Results: Parent–child attitude congruence was more prevalent among boys, and attitudes varied by ethnicity, parent education, and number of children. Positive parent–child attitudes for vigorous team sports were related to increased team participation and physical activity, as well as reduced TV and computer in boys and girls. Value of moderate intensity household chores, such as cleaning house and doing laundry, was related to decreased team participation and increased TV in boys. Only organized team sports, not general physical activity, was related to reduced TV and computer. Conclusion: Results support parents’ role in socializing children’s achievement task values, affecting child activity by transferring specific attitudes. Value of vigorous intensity sports provided the most benefits to activity and reduction of sedentary behavior, while valuing household chores had unexpected negative effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Physical activity patterns associated with cardiorespiratory fitness and reduced mortality: the Aerobics Center Longitudinal Study

OBJECTIVES: This study examined cross sectionally the physical activity patterns associated with low, moderate, and high levels of cardiorespiratory fitness. METHODS: Physical activity was assessed by questionnaire in a clinic population of 13,444 men and 3972 women 20 to 87 years of age. Estimated energy expenditure (kcal.wk-1) and volume (min.wk-1) of reported activities were calculated among individuals at low, moderate, and high fitness levels (assessed by maximal exercise tests). RESULTS: Average leisure time energy expenditures of 525 to 1650 kcal.wk-1 for men and 420 to 1260 kcal.wk-1 for women were associated with moderate to high levels of fitness. These levels of energy expenditure can be achieved with a brisk walk of approximately 30 minutes on most days of the week. In fact, men in the moderate and high fitness categories walked between 130 and 138 min.wk-1, and women in these categories walked between 148 and 167 min.wk-1. CONCLUSIONS: Most individuals should be able to achieve these physical activity goals and thus attain a cardiorespiratory fitness level sufficient to result in substantial health benefits.     

Effects of regular exercise in management of chronic idiopathic constipation

Regular physical exercise has long been considered in the management of chronic constipation. This recommendation is probably based on the assumption that exercise shortens the transit time through the gastrointestinal tract. However, on the basis of previous studies, the effect of exercise on the transit remains controversial at best. Therefore, it was the goal of the present study to assess the influence of regular physical exercise, what average people may consider routine exercise, in the management of chronic idiopathic constipation. The study population consisted of eight patients, seven women and a man, with chronic idiopathic constipation. They were studied for six weeks, including two weeks of rest and four weeks of regular exercise. Patients had a submaximal exercise test, before and after the exercise period, to determine their rate of perceived exertion (RPE), the target heart rate, and the intensity of exercise they can perform. In addition to their routine daily activities, they exercised 1 hr a day, five days a week according to their performance at the initial exercise tolerance test. They kept a daily activity log and maintained their normal dietary intake during this period. The patients overall physical activity was assessed by a pedometer. They also maintained a diary of the number and consistency of their bowel movements and the amount of straining required for defecation. The impact of exercise on constipation was assessed by utilizing an index that took into consideration all three parameters of bowel function. Results of the study revealed that patients covered 1.8+/-0.33 and 3.24+/-0.28 miles/day in the rest period and during the exercise period, respectively (P = 0.007). The intensity of exercise may have improved the level of training as reflected on the mean maximum time before and after exercise period (P = 0.039). This level of exercise did not improve their constipation indices, which were 9.11+/-0.65 and 8.57+/-1.08 in the rest and exercise periods, respectively (P = 0.68). In conclusion, physical activity, to the extent that people consider "regular exercise," does not play a role in the management of chronic idiopathic constipation.     

A year's memories: the calendar effect in autobiographical recall

When asked to recall autobiographical events from the past year, students tend to recall more incidents from the beginning and the end of school terms than from other periods. We investigated this calendar effect in Experiment 1 by comparing free recall at schools with different academic calendars. The event distributions tracked the individual calendars, helping to eliminate the possibility that the calendar effect is due to seasonal, nonschool factors, such as holidays. In Experiments 2-4, we checked explanations based on the ideas that events at term boundaries are more important or distinctive than others, that events are incorrectly dated too near the boundaries, and that boundaries serve as implicit cues for recall. These experiments revealed no evidence that importance or errors in dating could explain the effect. Manipulating cues, however, did change the size of the effect, implicating retrieval from very long-term memory as the effect's source. We suggest that when people have to search episodic memory, they consider their own calendar rhythms (such as a student's academic schedule) and let the temporal structure of their personal context guide their search.     

Physical activity in urban white, African-American, and Mexican-American women

PURPOSE AND METHODS: The purpose of this study was to analyze physical activity in a large, diverse sample of urban women (N = 521; X = 40.5 +/- 10.5 yr) relative to race/ethnicity, income, age, and education, using a sex-specific physical activity questionnaire. We also examined demographic and behavioral predictors of high levels (> or = 2000 kcal.wk-1) of leisure-time physical activity (LTPA; exercise, sports, recreational activities) in this population. RESULTS: The majority of women were sedentary (0-666 kcal.wk-1 in LTPA), and only 8% of African-American women (N = 6), 11% of Mexican-American women (N = 4), and 13% of white women (N = 55) participated in the level of physical activity recommended by the surgeon general (i.e., moderate to vigorous physical activity most days of the week for at least 30 min). Women of color, women over 40, and women without a college education had the lowest levels of participation in LTPA. Logistic regression analysis indicated that education was the only significant predictor of high LTPA in white women (P < 0.01) and marital status was the only significant predictor of high LTPA in minority women (P < 0.001). Age, body mass index (BMI; kg.m-2), income, self-rated health, alcohol intake, and smoking were not significant predictors of high LTPA for any of the women. Because the majority of adult women from this sample do not participate in adequate amounts of physical activity as recommended by the surgeon general, they may be at increased risk for hypokinetic diseases. CONCLUSIONS: These results indicate that public health efforts to increase physical activity in women should be focused on women of color, women over 40, and women without a college degree. More attention to predictors of physical activity that are specific to race or ethnicity may improve intervention program design and implementation.     

Thoracic complications associated with utilization of the air turbine dental drill

BACKGROUND: The prevalence of asthma is rising and there are recent reports of increasing asthma rates among top level skiers and runners in the Nordic countries. METHODS: The lifetime occurrence of pulmonary diseases (asthma, chronic bronchitis, emphysema) and current bronchitis symptoms was compared in former elite male athletes (n = 1282) who represented Finland between 1920 and 1965 at least once in international competitions and controls (n = 777) who, at the age of 20, were classified as healthy and who responded to a questionnaire in 1985. The presence of disease and symptoms was identified from the questionnaire and, in the case of asthma, also from a nationwide reimbursable medication register. The death certificates of the subjects of our original cohort who died between 1936 and 1985 were also investigated to determine the cause of death. RESULTS: The occurrence of the pulmonary diseases was associated with age, smoking habits, occupational group, and a history of exposure to chemicals. After adjusting for these variables, athletes who participated in mixed sports (odds ratio (OR) 0.46, 95% confidence interval (CI) 0.23 to 0.92) and power sports (OR 0.43, 95% CI 0.21 to 0.87) had lower odds ratios for emphysema, and endurance sports athletes had a lower odds ratio for the presence of at least one pulmonary disease (OR 0.53, 95% CI 0.28 to 0.98) when compared with controls. Athletes also tended to have fewer reimbursable medications for asthma and fewer current symptoms for chronic bronchitis. Between 1936 and 1985 two controls but none of the athletes died of asthma. CONCLUSIONS: The lifetime occurrence of asthma or other pulmonary diseases is not increased in former elite athletes, and exercise alone, even in a cold environment, did not appear to increase the prevalence of asthma, at least up to the mid 1980s.     

The effect of portal hypertension on transforming growth factor-alpha and epidermal growth factor receptor in the gastric mucosa of rats

BACKGROUND: The physical activity levels of US children are declining. Opportunities for physical activity within city schools are constrained by time and space limits. This study determined whether a supplemental program of physical activity would significantly alter the fitness levels of low-income, minority, urban elementary schoolchildren. METHODS: Ninety-nine students from two Cleveland Public Schools served as subjects. One school received a 15-week intervention program where teams of two medical students met with urban elementary schoolchildren three times a week for physical activity sessions. The other school served as a control and received no supplemental activity other than a regularly scheduled physical education class held once a week. We obtained field measurements of skinfold thickness, heart rate response to submaximal exercise, and sit and reach flexibility. RESULTS: The supplemental activity group showed significant improvements in flexibility, body composition, and heart rate response to submaximal exercise. CONCLUSIONS: This investigation indicates that a program of fitness activities conducted within the classroom can significantly improve levels of fitness in urban elementary schoolchildren.     

Effects of an exercise program on musculoskeletal symptoms and physical capacity among nursing staff

Musculoskeletal disorders are a major health problem, and nursing staff are often seen as a risk group. The purpose of this study was to evaluate the effect of a weekly exercise program among nursing staff on musculoskeletal symptoms and to study the relation to changes in physical capacity. A total of 106 nurses and nursing aides from four geriatric wards were invited to participate; 86 accepted. A cross-over design was used. The staff from two wards were assigned to an exercise period and the staff from the other wards to a control period for the first intervention period. After a wash-out period, the intervention changed. For the exercise periods the staff were invited to participate in an exercise program twice a week for 8 weeks. In total 50 subjects participated more than 8 times regularly during the exercise periods (participants = > or = 8 times regular participation, nonparticipants = < 8). During the control periods 78 subjects attended without intervention. Assessments were made with a standardized questionnaire for analysis of musculoskeletal and psychosomatic symptoms, testing of muscle strength in m. quadriceps with a Cybex dynamometer, and testing of cardiovascular capacity with a Dynavite computerized exercise bicycle before and after the exercise periods. The muscle strength in m. quadriceps increased more during the exercise periods compared with the control periods, explained primarily by the subgroup of nonregular exercisers and those > or = 40 years of age. The number of musculoskeletal symptoms tended to decrease more in the subgroup of nonregular exercisers (those who exercised less than once a week in their spare time) during the exercise periods compared with the nonregular exercisers during the control periods. Comparisons within groups showed a decrease in the number of musculoskeletal symptoms within the exercise periods, explained primarily by a decrease among the participants rather than among the nonparticipants. The decrease within the participants was explained primarily by the subgroup of nonregular exercisers and those > or = 40 years of age. An increase in cardiovascular capacity and a tendency to increase in muscle strength in m. quadriceps were seen among the participants, explained primarily by the effect in the subgroup of nonregular exercisers. The study suggests that a moderate weekly exercise program, performed in a group, among nursing staff affects physical capacity and the number of musculoskeletal symptoms for subjects who are nonregular exercisers and probably subjects > or = 40 years of age.     

Aggression and psychopathology in persons with severe or profound mental retardation

In order to determine key competences required of occupational medicine specialists, common throughout Europe, a questionnaire has been developed and distributed among several European countries. The questionnaire contained 115 subjects related to 8 fields of activities carried out by occupational medicine physicians (occupational hazards to health, assessment of disability and fitness for work, communications, research methods, management, environmental medicine, occupational health law and ethics, and health promotion). In each of these fields, competences were classified into three following categories: knowledge, experience and skills. Respondents were asked to allocate a score from 0 to 5 for each subject, where 0 = not necessary; 1 = of minimum importance, and 5 = most important or essential. In Poland the questionnaire was distributed among two groups of specialists: group I--experienced specialists in occupational medicine (leading representatives of occupational health care management), and group II--relatively younger and less experienced occupational medicine physicians, participating in the specialist training, organised by The Nofer Institute of Occupational Medicine. A comprehensive analysis of the completed questionnaires was carried out in two dimensions: substantive (the importance of individual competences as perceived by Polish specialists in occupational medicine), and comparative (evaluation and interpretation of similarities and differences between two groups of respondents). A hierarchy of requirements, occupational medicine training in Poland is to satisfy, was reconstructed with two sets of competences, one recognised by respondents as needless and the other recognised as useful with different grades of importance. Some characteristic differences in opinions between two groups studies were highlighted.     

Quantitative computed tomography for measuring bone mineral density in athletes

We studied the effect of different training patterns on vertebral trabecular and cortical bone mineral density (BMD) in male athletes using quantitative computed tomography. Vertebral trabecular (t) and cortical (c) BMDs of the first three lumbar vertebrae were measured using single energy quantitative computed tomography in 51 athletes including 10 weight lifters (mean age 20 years), 13 soccer players (mean age 27 years), 28 wrestlers (mean age 17 years), and 45 age-matched volunteers (mean age 21 years). Measured BMDs were correlated with age, body height and weight, training hours per week, sports years, and type of physical activity. Vertebral tBMDs were found to be 44%, 23%, and 24% higher in the weight lifters, soccer players, and wrestlers, respectively, compared with the volunteers. The corresponding cBMDs were 18%, 6%, and 11% higher than that of volunteers. There was significant correlation between the trabecular and cBMD, and height of the athletes, sports years, training hours per week, and physical activity. The most significant correlation with BMD was the type of physical activity. Both the height of the subjects and physical activity variables showed variations of 47% and 32% in trabecular and cBMD, respectively. According to the multiple analysis of variance (MANOVA) only the physical activity factor was effective, with a significance level of P < 0.01; the other factors and interactions were not effective (P > 0.05) on trabecular and cBMD. Different training patterns have a different anabolic effect on both trabecular and cBMDs of the vertebrae, and this effect is more pronounced on the trabecular compartment. Weight lifting showed the highest anabolic effect on both trabecular and cBMDs compared with soccer playing and wrestling. Of the independent variables, physical activity showed the highest anabolic effect on the vertebrae. These results may have implications for devising exercise strategies to reduce the possibility of fracture in old age.     

Assessing adult leisure activities: An extension of a self-report activity questionnaire.

Everyday leisure activities in adulthood and old age have been investigated with respect to constructs such as successful aging, an engaged lifestyle, and prevention of age-related cognitive decline. They also relate to mental health and have clinical value, as they can inform diagnosis and interventions. In the present study, the authors enhanced the content validity of the Victoria Longitudinal Study activity questionnaire by adding items on physical and social activities and validated a shortened version of the questionnaire. The proposed leisure activity model included 11 activity categories: 3 types of social activities (i.e., activities with close social partners, group-centered public activity, religious activities), physical activities, developmental activities, experiential activities, crafts, game playing, TV watching, travel, and technology use. Confirmatory factor analyses validated the proposed factor structure in 2 independent samples. A higher order model with a general activity factor fitted the activity factor correlations with relatively little loss of fit. Convergent and discriminant validity for the activity scales were supported by patterns of their correlations with education, health, depression, cognition, and personality. In sum, the scores derived from of the augmented Victoria Longitudinal Study activity questionnaire demonstrate good reliability, and validity evidence supports their use as measures of leisure activities in young, middle-aged, and older individuals. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evening activity, sleep mentation, and subjective sleep quality.

Investigated sleep mentation and subjective sleep quality in 15 young males after 3 kinds of evening activities: 6 hr. of exercise, 6 hr. of studying, and 6 hr. of relaxation. During REM periods, Ss dreamt less about physical activity after the evening of exercise and less about thinking and problem solving after studying. After studying, there was more social interaction/character in S's dreams. Mentation from NREM periods after exercise also showed less physical activity, but after studying it was characterized by a more tense mood. Ss were involved more in what was going on in NREM mentation after studying. Ss said they slept soundest after exercise, and the more they felt involved in REM mentation, the less soundly they reported sleeping. (18 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An anamnestic-observational estimation of the postural-energy-motor commitment of occupational activities via a questionnaire

A simple questionnaire for the quali-quantitative clinical assessment of the physical requirements in habitual occupational activities has been fixed. The assessment goes through the classification of qualitative, dimensional, temporal parameters referred by the patient as characteristic of the occupational activity. As a result the risk factors related to postures and movements are highlighted, and an esteem of the energy expenditure is obtained from a predictive equation which has been formulated on the basis of some important references. The energy expenditure of three homogeneous occupational phases was estimated through the equation, and then measured during a simulation of the same activities performed in a laboratory by 7 subjects. The estimated and the measured values were compared also with the esteems obtained from validated predictive equations (Garg et al, 1978). The predictivity of our equation was measured. As an on-site assessment, detailed written reports of 18 occupational phases were submitted to 6 differently trained observers and were analyzed through the questionnaire; the variability inter-observer was studied.