Relationship functioning moderates the association between depressive symptoms and life stressors.

Data from 172 newlywed couples were collected over the first 4 years of marriage to test how behaviors demonstrated during marital interactions moderate associations between depressive symptoms and subsequent life stressors. Depressive symptoms and behaviors coded from problem-solving and social support interactions were analyzed as predictors of nonmarital stressors that were interpersonal and dependent on the participant's actions. Behavioral codes were found to moderate 3 of 16 symptom-to-life event associations for husbands. Husbands' reports of more depressive symptoms predicted greater levels of stress when husbands' positive affect and hard negative affect during problem-solving were relatively infrequent and when wives made frequent displays of positive behaviors during husbands' support topics. These effects remained after controlling for marital satisfaction. For wives, behavioral moderators did not interact with depressive symptoms to predict changes in stress, but marital satisfaction consistently interacted with depressive symptoms to predict future stressors beyond interpersonal behaviors. Specifically, for wives, stress generation was more evident when relationship satisfaction was low than when it was high. Our results, though different for men and women, suggest that relationship functioning can alter associations between depressive symptoms and life stress in the early years of marriage. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Relation of social and academic competence to depressive symptoms in childhood.

Relation of depressive symptoms to social and academic competence was examined in 750 4th-grade students. Self-report, peer-nomination, and teacher-rating measures of all 3 constructs were obtained. The multitrait-multimethod data were examined with confirmatory factor analysis and multivariate analysis of variance (MANOVA). Stronger correlations than have previously been reported were found between depressive symptoms and both kinds of competence. Social and academic incompetence had an additive effect on depressive symptoms. Children who were both socially and academically less competent had more symptoms of depression than children who had only 1 problem area. Children with only 1 problem area had more symptoms of depression than did children who were neither socially nor academically less competent. Gender differences in other-rated measures of competence were also evident. Implications for a competency-based model of depression are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Illusion of control: Invulnerability to negative affect and depressive symptoms after laboratory and natural stressors.

Examined whether individual differences in susceptibility to the illusion of control predicted differential vulnerability to depressive responses after a laboratory failure and naturally occurring life stressors. The illusion of control decreased the likelihood that Ss (N?=?145) would (1) show immediate negative mood reactions to the lab failure, (2) become discouraged after naturally occurring negative life events, and (3) experience increases in depressive symptoms a month later given the occurrence of a high number of negative life events. In addition, the stress-moderating effect of the illusion of control on later depressive symptoms appeared to be mediated in part by its effect on reducing the discouragement Ss experienced from the occurrence of negative life events. These findings provide support for the hopelessness theory of depression and for the optimistic illusion–mental health link. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Relation of depressive symptoms to the structure of self-knowledge in childhood.

Measures of positive, negative, and total self-complexity (or self-concept differentiation), self-compartmentalization, self-reported negative events, and self-reported symptoms of depression, anxiety, and conduct disorder were completed by 4th-, 6th-, and 8th-grade public school students. Measures of self-complexity and self-compartmentalization related positively to depression. Results were consistent across grade level. Controlling for anxiety and conduct disorder did not attenuate these effects. Results for positive and negative self-complexity were essentially equivalent to those for total self-complexity. Interactions between self-complexity and negative event and between self-compartmentalization and differential importance were not significant. The authors propose that self-complexity in childhood constitutes a response to negative self-relevant information sometimes conveyed by negative events. The authors conjecture that self-complexity does not buffer the impact of negative events in childhood but may serve as a buffer later in life. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Maternal depressive symptoms and depressive symptoms in adolescents

The relationship between maternal depressive symptoms and rates of adolescent (15-16 years) depressive symptoms was studied in a birth cohort of 934 New Zealand children. There was a clear correlation between maternal depressive symptoms and subsequent depressive symptoms in adolescent females (r = .44) but no association (r = -.01) between maternal depressive symptoms and depressive symptoms in adolescent males. Subsequent analysis suggested that the correlation between maternal depression and depressive symptoms in adolescent females was largely explained by the associations of both measures with a series of social and contextual factors including social disadvantage, marital discord and family adversity. It is concluded that maternal depression is only associated with depression in adolescence insofar as maternal depression is associated with social disadvantage, marital discord or family adversity.     

Relation of light and exercise to seasonal depressive symptoms: preliminary development of a scale

In the first large-scale survey on the use of alcohol and tobacco and the inhalation of paint thinner by Japanese high school students, a higher percentage of respondents reported past or regular use of these substances than in a 1978 survey. The survey was conducted in 44 high schools. The 14,438 respondents (ages 15-18 years) represented 9 of Japan's 47 geographically distinct urban and rural prefectures. Most (76%) reported that they had consumed alcohol at some time, and 50% reported drinking on a regular basis. Alcohol consumption, drinking partners, and motivation for drinking were compared by student gender, geographic region, and years of education. Fewer students reported smoking cigarettes: 32% had smoked at some time, and 14% smoked regularly. Inhalation of paint thinner was rare: 3% had purposely inhaled it, and 1% had abused it. A significant percentage of the alcohol drinkers also used tobacco and/or thinner, a tendency that was the same despite differences in gender, grade in high school, and urban or rural geographic region. A tendency toward polysubstance use was evident among these high school students.     

Burden of illness, metabolic control, and complications in relation to depressive symptoms in IDDM patients

Relationships between demographic-, treatment-, and sickness-related factors, metabolic control (HbA1c), perceived burden of illness, and degree of depressive symptoms were examined in a group of 155 insulin-dependent diabetic patients, aged 35.3 +/- 8.9 years. The patients completed a questionnaire measuring depressive symptoms and three aspects of perceived burden of illness. No gender differences in HbA1c level or occurrence of late diabetic complications were found. Both men and women showed a modestly elevated degree of depression compared with norm groups. Self-reported burden of illness was strongly related to depression but was largely unrelated to objective disease-related measures. Level of depression was correlated neither with degree of metabolic control nor with the presence of such late diabetic complications as retinopathy and nephropathy. Some 44% of the variance in depression could be explained by worries about complications in those patients with the lowest HbA1c levels, by perceived restrictions in everyday life in patients with intermediate metabolic control, and by problems of glycaemic regulation in patients with poor metabolic control. Degree of depression was largely unrelated to disease severity, but was found to be related to the perceived daily burden of living with the disease, the specific worries and concerns associated with a depressed mood varying with degree of metabolic control.     

A comparison of primary stressors, secondary stressors, and depressive symptoms between elderly caregiving husbands and wives: The caregiver health effects study.

The present study examined gender differences in the experience of primary and secondary caregiving stressors, depressive symptoms, and their interrelationships using a sample of 283 elderly spouse caregivers (145 women, 138 men). Two primary stressors, two secondary stressors, and depressive symptoms were assessed. In general, t-tests indicated that caregiving husbands experience fewer stressors and depressive symptoms than their female counterparts. Multiple group analysis revealed that the primary stressors were more useful in explaining variance associated with the secondary stressors for women than men and that the path coefficients linking amount of caregiving assistance to caregivers' activity restriction was significantly different across men and women. Other paths linking primary stressors, secondary stressors, and depressive symptoms, however, were statistically equivalent across men and women. Hence, although caregiving women and men may vary in their reports of caregiving stressors, the complexity of the caregiving experience appears to be quite uniform for both groups. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Compensated cirrhosis due to viral hepatitis: using MR imaging to predict clinical progression

OBJECTIVE: The goal of our study was to determine the relative value of multiple MR features in predicting clinical progression of disease in patients with compensated cirrhosis. MATERIALS AND METHODS: The MR examinations of 23 patients with compensated cirrhosis (Child A) were retrospectively reviewed independently by two radiologists and correlated with clinical progression after follow-up of all patients for more than 12 months each (12-87 months: average, 39 months) by the same experienced hepatologist. Clinical progression was defined as an increase of the Child grade or the Pugh score by at least two points (5- to 15-point scale). In the initial MR study of each patient, the following MR findings were assessed by each radiologist independently: volume indexes of the spleen and each segment of the liver (based on three-axis measurements), nodular surface, regenerative nodules, ascites, iron or fat deposition, and varices or collaterals. RESULTS: The volume index of the spleen was the most accurate predictor of clinical progression (p = .001), the next most accurate was the number of sites of varices or collaterals (p = .002), and the third most accurate was the ratio of caudate lobe to right lobe volume index (p = .02). Other MR findings failed to correlate with clinical progression. CONCLUSION: As revealed on MR imaging, the volume index of the spleen, the severity of varices, and the volume index ratio of caudate lobe to right lobe can be used to help predict clinical progression of disease in patients with compensated cirrhosis.     

Relation between depressive symptoms and stressful life events in a sample of disadvantaged mothers.

The bidirectional relation between life events and self-reported depression was examined across a 1-year period. With Time 1 depression controlled, Time 2 stress accounted for an additional 10% of Time 2 depressive symptoms. Health-related stress, family violence, and financial stress at Time 2 predicted Time 2 depression after control for Time 1 depression. With Time 1 stress controlled, Time 2 depression accounted for 8% of the variance in Time 2 stress. Time 2 depression predicted Time 2 health-related stress, financial stress, household changes, spouse–partner stress, family violence stress, and substance abuse stress, controlling for each of these stressors at Time 1. The results describe a complex relation between stress and depression and suggest that the relation between stress and depression is moderated by the type of stress. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Self-blame and depressive symptoms.

Investigated whether internal attributions for bad events are always associated with depression. The depressive symptoms of 86 female undergraduates correlated with blame directed at their own characters. In contrast, blame directed at their own behaviors correlated with lack of depressive symptoms. Behaviorally attributed bad events were seen as more controllable and their causes less stable and less global than were characterologically attributed bad events and their causes. Characterological blame increased with more negative life events during the last year, implying that individuals who blame their character may arrive at this attributional style by a covariation analysis. Finally, characterological blame did not precede the onset of depressive symptoms 6 or 12 wks later. As a result, characterological blame may be a strong concomitant of depression but not a cause. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social support, coping, and depressive symptoms in a late-middle-aged sample of patients reporting cardiac illness

This study tests a 1-year predictive model of depressive symptoms in a late-middle-aged sample of patients reporting diagnoses of cardiac illness. Results based on 325 individuals (248 men and 77 women) diagnosed with chronic cardiac illness, 71 individuals (52 men and 19 women) diagnosed with acute cardiac illness, and 219 healthy controls (129 men and 90 women) strongly supported the hypotheses. Compared with healthy persons, individuals with chronic and those with acute cardiac illness reported more depressive symptoms at follow-up. Women overall showed more depressive symptoms than did men, and women with cardiac illness were particularly vulnerable to behavioral manifestations of depressive symptoms. Integrative time-lag and prospective structural equation models indicated that, for individuals with cardiac illness, social support and adaptive coping strategies predicted fewer depressive symptoms.     

Minor depressive disorder and subsyndromal depressive symptoms: functional impairment and response to treatment

BACKGROUND: This study quantifies functional impairment and depressive symptomatology in patients with minor depressive disorder (MinD) and subsyndromal depressive symptomatology (SSD) before and after 8 weeks of treatment with fluvoxamine. Study patients were compared and contrasted with archival data from a sample of the general population measured by the Medical Outcome Survey Short Form 36. METHOD: Fifteen patients with MinD and 15 patients with SSD were identified from primary care clinics, referrals and newspaper advertisements. Patients signed informed consent and were offered open label treatment with fluvoxamine 25-100 mg/day. Patients were seen biweekly and measures of functional impairment and depressive symptomatology were gathered systematically. RESULTS: MinD and SSD were associated with dysfunction and disability when compared to archival normative data from the general population. Eight week treatment with fluvoxamine was associated with a substantial decrease in depressive symptomatology and a normalization of psychosocial functioning. CONCLUSION: This is the first study to quantify functional impairment and the severity of depressive symptomatology in a clinical sample of patients with MinD and SSD, and to demonstrate that treatment with a selective serotonin reuptake inhibitor decreases depressive symptomatology and improves psychosocial functioning. Placebo-controlled double-blind confirmation of these preliminary observations seems warranted.     

Relation of negative affectivity to self-reports of job stressors and psychological outcomes.

A total of 250 new women teachers participated in a longitudinal study of the influence of negative affectivity (NA) on the relation of self-report work-environment measures to psychological outcomes. Three "neutrally worded" work-environment measures were specially constructed to minimize confounding with NA. The work-environment measures were moderately related to postemployment depressive symptoms, job satisfaction, and, among Whites but not among a principally Black and Hispanic subsample, motivation. Correlation and regression coefficients were largely unchanged when the preemployment psychophysiologic symptoms scale and the Center for Epidemiologic Studies-Depression Scale (L. S. Radloff; see record 1979-10129-001), factors that tap NA, were controlled. Findings suggest NA does not overly distort the relation of some self-report work-environment measures to depressive symptoms, satisfaction, and motivation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Emergence of attributional style and its relation to depressive symptoms.

The development of depressive attributional style (AS) and its role as a cognitive diathesis for depression were examined in children and adolescents (Grades 2-9). In a 4-wave longitudinal study of 3 overlapping age cohorts, AS, negative life events, and depressive symptoms were evaluated every 12 months. Consistency of children's attributions across situations was moderately high at all ages. The cross-sectional structure of AS changed with age, as stability became a more salient aspect of AS than internality and globality. The structure of AS also changed, becoming more traitlike as children grew older. In longitudinal analyses, evidence of a Cognitive Diathesis × Stress interaction did not emerge until Grades 8 and 9, suggesting that AS may not serve as a diathesis for depression at younger ages. Results suggest that attributional models of depression may require modification before they are applied across developmental levels. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Changes in depressive self-schemata and depressive symptoms following cognitive therapy.

Examined the effects of 6–8 sessions of Beck's cognitive therapy on mildly and moderately depressed college students' depressive symptoms and depressive self-schemata. Participants were randomly assigned to either cognitive therapy (n?=?31) or no treatment (n?=?43). The Beck Depression Inventory was used to assess depressive symptoms, and self-referent judgment, recall, and reaction time (RT) measures were used to assess depressive self-schemata. Results support the efficacy of cognitive therapy in reducing depressive symptoms and depressive self-schemata, as measured by self-referent judgment and self-referent recall. The reduction in the recall of negative self-referent judgments may play a role in the outcome of cognitive therapy for depression. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Dimensions of dysfunctional attitudes as vulnerabilities to depressive symptoms.

Empirical tests of the diathesis-stress component of A. T. Beck's (1976; A. T. Beck, A. J. Rush, B. E. Shaw, & G. Emery, 1979) cognitive theory of depression have generally not yielded positive results. The resulting focus on conceptual and methodological concerns has diverted attention from the more fundamental issue of how validly vulnerability is measured. The present investigation uses the Dysfunctional Attitude Scale (DAS; A. N. Weissman, 1979; A. N. Weissman & Beck, 1978), the most commonly used measure of vulnerability in this area, but adopts a more in-depth approach by examining DAS factors in addition to the typical total score. This study involved a sample of undergraduates who had never before taken a college-level examination. The dimension of the DAS measured by the Perfectionistic Achievement factor had the strongest relationship to increased depressive symptoms in response to poorer-than-expected performance on the examination. Implications for future research in this area are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hypothalamic-pituitary-adrenal axis activity in depressive illness. Its relationship to classification

Serum cortisol response to the 1-mg overnight dexamethasone suppression test was studied in 221 depressed patients and 109 nondepressed psychiatric controls. Nonsuppression distinguished patients with primary unipolar depression (65/146) from patients with secondary unipolar depression (0/42) and nondepressed controls (0/109). Furthermore, nonsuppression distinguished the three familial subtypes of primary unipolar depressive illness: familial pure depressive disease (FPDD; 38/50 patients), sporadic depressive disease (SDD; 24/55 patients), and depression spectrum disease (3/41 patients). Moderate elevations in baseline serum cortisol levels were found in FPDD, SDD, and bipolar depression. Medication did not affect the results. The data suggest that the depressive syndrome is composed of separate illnesses, each of which has a distinctive pattern of hypothalamic-pituitary-adrenal axis activity during the depressed state as well as a specific clinical and familial psychiatric history.     

Neuroendocrine measures and lymphocyte subsets in depressive illness: influence of a clinical interview concerning life experiences

The effects of a clinical interview concerning either positive or negative day-to-day events on lymphocyte subpopulations, and on plasma cortisol, ACTH and norepinephrine, were determined in depressive patients (major depressive and dysthymic) and in normal controls. Irrespective of its content, the interview provoked an elevation of circulating natural killer (NK) cells, suggesting that this effect was related to either a change in mood state (regardless of its valence) or to the stress associated with the interview procedure. Since the interview did not influence plasma cortisol, ACTH or norepinephrine, it is likely that the NK cell variations were independent of these endocrines. Although basal NK cells were elevated in the depressive group relative to controls, the extent of the NK cell increase provoked by the interview was comparable in depressive and control subjects. The failure to detect differences between these populations could not be attributed to ceiling effects precluding more pronounced alterations in the depressed subjects. Indeed, variations of circulating cell subtypes were found to be exquisitely sensitive to differences in stressor intensity. In a subset of control subjects, a more potent stressor (anticipation of an academic examination) increased the plasma endocrine levels, increased circulating NK cell number beyond that associated with the interview stress, and provoked an increase of several T cell subsets (CD3, CD4 and CD8). Evidently, while a clinical interview may be sufficiently stressful to influence circulating NK cells, the stress of such a procedure seems no greater in depressed than in control subjects. It is suggested that although depressed patients may exhibit higher basal NK levels, this effect is likely not related to increased reactivity to stressors.