共查询到16条相似文献,搜索用时 140 毫秒
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目的考察一种新型复合防腐剂在化妆品基质中的作用效果。方法采用微生物挑战性实验验证复合防腐剂对微生物的抑菌能力。结果由含量分别为0.05%、0.10%和0.20%的对羟基苯甲酸甲酯、Euxyl K220及Euxyl PE9010复配而成的复合防腐剂对抑制细菌、霉菌效果优良。结论应用于化妆品基质中的新型复合防腐剂:0.05%甲酯、0.10%Euxyl K220、0.20%Euxyl PE9010抑菌效果优良,通过了挑战性实验。根据化妆品的配方结合实际情况,该种新型复合防腐剂可行性很强。 相似文献
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《日用化学工业》2021,51(10)
通过中和剂验证、防腐挑战等试验对市售无添加防腐剂化妆品的防腐体系进行效能评价。采集无防腐剂的化妆品15批次,按《化妆品安全技术规范》(2015年版)(以下简称《规范》)进行菌落总数、霉菌和酵母菌以及pH值测定,参照GB 5009.238—2016《食品安全国家标准食品水分活度的测定》测定水活度,参考国外相关标准进行防腐挑战试验。菌落总数、霉菌和酵母菌的结果均符合《规范》要求。中和剂验证试验有3批(20%)需要替换中和剂或进一步稀释。防腐挑战试验中有14批细菌7天可下降大于99.9%,9批霉菌和酵母菌7天可下降大于90%。9批(60%)样品符合CTFA和AOAC非眼用化妆品的要求。样品普遍为弱酸性或中性,pH值最高9.73,最低4.68;水活度值集中在0.850~1.000,最低为0.643。综合结果表明:按《规范》进行化妆品微生物检验漏检风险较大,部分无添加防腐剂化妆品的防腐体系可能存在安全隐患;中和剂验证及防腐挑战试验亟需加入我国标准体系。 相似文献
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本文参照美国化妆品、盥洗用品和香精协会(CTFA)推荐的防腐体系效能评价方法,研究了不同产品在相同防腐条件下,微生物挑战试验结果的差异性。 相似文献
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目的考察不同复配比的防腐剂在化妆品基质中的作用效果,寻求一种新型复合防腐剂。方法采用微生物挑战性实验验证复合防腐剂对微生物的抑菌能力。结果在面膜液基质中,对羟基苯甲酸酯类复配而成的复合防腐剂对抑制细菌效果较好,抑制霉菌效果较弱。对羟基苯甲酸酯类及苯氧乙醇复配而成的复合防腐剂抑菌效果较好。在粉底霜基质中,由含量分别为0.20%、0.10%和0.20%的对羟基苯甲酸甲酯、对羟基苯甲酸丙酯及苯氧乙醇复配而成的复合防腐剂对抑制细菌、霉菌效果达到最好且含量相对较低,为最优复合防腐剂。结论应用于面膜基质液和粉底霜基质液的复合防腐剂:0.12%甲酯、0.02%丙酯、0.3%的苯氧乙醇和0.20%甲酯、0.1%丙酯、0.2%苯氧乙醇通过了挑战性实验。根据化妆品的配方结合实际情况,该两种新型复合防腐剂可行性强。 相似文献
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1999年中国化妆品工业平稳发展,名牌产品为市场主导。市场竞争激烈。厂家不断推出新品,销售触角直接指出消费者,并指出化妆品包括进口化妆品质量值得重视。2000年中国将加入世贸组织,中国化妆品行业是机遇与挑战并存,中国化妆品的市场必须国际市场国际化。 相似文献
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对化妆品的生物物理学功效评价方法进行了综述,重点介绍了保湿、防晒、美白和皮肤表面轮廓的评价方法,另外还对皮肤表面油脂、除臭止汗剂、皮肤清洗和皮肤弹性的评价方法进行了简要介绍. 相似文献
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R. S. Farag F. M. Hewedi M. A. I. Salem S. M. S. El-Tantawy 《European Journal of Lipid Science and Technology》1986,88(8):321-325
Some treatments were conducted for prolonging the self life of broiler meat such as storage at two different temperatures (3 °C and -18 °C) with and without adding chemical preservatives (NaCl, polyphosphate and a mixture of them). Fatty acid composition of blended skin tissue and subcutaneous carcasses lipids were qualitatively and quantitatively determined by gasliquid chromatography. The fatty acid analysis indicated that 16:0 and 18:1 were the most predominant saturated and unsaturated acids of fresh skin tissue and subcutaneous carcasses lipids. Dipping carcasses in hot water alone and with NaCl, polyphosphate or a mixture of them exhibited very little effect on the fatty acid pattern. Storage at 3 °C led to conversion of some long-chained and unsaturated fatty acids to mediumchained and saturated ones. Dipping carcasses in tap or hot water with or without preservatives caused quantitative changes in 16 :0,18 :0,18 :1 and 18 :2 acids. In general, the most efficient treatment towards keeping carcasses quality is storage at -18 °C without adding any chemical preservatives. 相似文献
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Ana B. Moldes Lorena Rodríguez-Lpez Myriam Rincn-Fontn Alejandro Lpez-Prieto Xanel Vecino Jos M. Cruz 《International journal of molecular sciences》2021,22(5)
This article includes an updated review of the classification, uses and side effects of surfactants for their application in the cosmetic, personal care and pharmaceutical industries. Based on their origin and composition, surfactants can be divided into three different categories: (i) synthetic surfactants; (ii) bio-based surfactants; and (iii) microbial biosurfactants. The first group is the most widespread and cost-effective. It is composed of surfactants, which are synthetically produced, using non-renewable sources, with a final structure that is different from the natural components of living cells. The second category comprises surfactants of intermediate biocompatibility, usually produced by chemical synthesis but integrating fats, sugars or amino acids obtained from renewable sources into their structure. Finally, the third group of surfactants, designated as microbial biosurfactants, are considered the most biocompatible and eco-friendly, as they are produced by living cells, mostly bacteria and yeasts, without the intermediation of organic synthesis. Based on the information included in this review it would be interesting for cosmetic, personal care and pharmaceutical industries to consider microbial biosurfactants as a group apart from surfactants, needing specific regulations, as they are less toxic and more biocompatible than chemical surfactants having formulations that are more biocompatible and greener. 相似文献