共查询到19条相似文献,搜索用时 78 毫秒
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三维工程设计模式浅谈 总被引:2,自引:0,他引:2
工厂全生命周期管理理念中最主要的部分——参数化三维工厂设计软件广泛得以运用。三维设计的优点已被大家所公认,三维模型也被广泛应用,但是要充分发挥利用好这种三维设计的优势,则需要一套适合于三维工程设计的管理模式来指导。而这个管理模式主要是围绕三维模型为中心开展的,设计过程服务于模型,设计结果出之于模型。 相似文献
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文章介绍了低浓度煤层气深冷液化以及三维工厂设计技术,从三维工厂设计功能模块的角度,介绍了三维工厂设计在低浓度煤层气深冷液化产业以及深冷液化产业中橇装化设备研发方面的作用,并对未来三维工厂设计的发展趋势进行了展望。 相似文献
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3D打印是近年来发展起来的高新技术,已在机械制造等行业取得很大成功,在材料和建筑等领域也有所发展.本文在介绍通用3D打印技术进展的基础上,着重阐述了混凝土材料的传统施工工艺、国内外3D打印混凝土技术与其材料和施工工艺的发展现状,讨论了3D打印混凝土当前所面临的问题,并对3D打印混凝土提出了未来展望. 相似文献
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Chemical Synthesis of Side-Chain-Hydroxylated Vitamin D3 Derivatives and Their Metabolism by CYP27B1
Ryota Sakamoto Akiko Nagata Haruki Ohshita Yuka Mizumoto Miho Iwaki Dr. Kaori Yasuda Prof. Toshiyuki Sakaki Dr. Kazuo Nagasawa 《Chembiochem : a European journal of chemical biology》2021,22(19):2896-2900
1α,25-Dihydroxyvitamin D3 (abbreviated here as 1,25D3) is a hormonally active form of vitamin D3 (D3), and is produced from D3 by CYP27 A1-mediated hydroxylation at C25, followed by CYP27B1-mediated hydroxylation at C1. Further hydroxylation of 25D3 and 1,25D3 occurs at C23, C24 and C26 to generate corresponding metabolites, except for 1,25R,26D3. Since the capability of CYP27B1 to hydroxylate C1 of side-chain-hydroxylated metabolites other than 23S,25D3 and 24R,25D3 has not been examined, we have here explored the role of CYP27B1 in the C1 hydroxylation of a series of side-chain-hydroxylated D3 derivatives. We found that CYP27B1 hydroxylates the R diastereomers of 24,25D3 and 25,26D3 more effectively than the S diastereomers, but shows almost no activity towards either diastereomer of 23,25D3. This is the first report to show that CYP27B1 metabolizes 25,26D3 to the corresponding 1α-hydroxylated derivative, 1,25,26D3. It will be interesting to examine the physiological relevance of this finding. 相似文献
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介绍某醋酸仲丁酯项目所采用的"加成合成新生产技术",着重论述了本次使用AutoPLANT 3D配管设计的几个特点,同时设计工作中贯穿了健康、安全、环保的理念。 相似文献