Returning basic research to the community: A relationship between scientist and citizen.

Demonstrates how citizens can use the information gained through a basic research project to benefit both the social scientist and the community being studied. A case study is presented based on the experience of the Neighborhood Participation Project, which studied citizen participation in a racially integrated neighborhood in Nashville, Tennessee. After gathering longitudinal data from residents, the researchers embarked on a process of working with a neighborhood agency (Neighborhood Housing Services) and a neighborhood organization (Sunnyside Community Citizens) to give away both the process and content of their research. The case study is presented to highlight some important issues for returning basic research to the community. The authors suggest that creating partnerships and linkages between social scientists and citizens can improve the quality of social science research, enhance the potential for using research, encourage public support for social science research, and help people help themselves. (37 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance

The threat to human health posed by antibiotic resistance is of growing concern. Many commensal and pathogenic organisms have developed resistance to well established and newer antibiotics. The major selection pressure driving changes in the frequency of antibiotic resistance is the volume of drug use. However, establishing a quantitative relationship between the frequency of resistance and volume of drug use has proved difficult. Using population genetic methods and epidemiological observations, we report an analysis of the influence of the selective pressure imposed by the volume of drug use on temporal changes in resistance. Analytical expressions are derived to delineate key relationships between resistance and drug consumption. The analyses indicate that the time scale for emergence of resistance under a constant selective pressure is typically much shorter than the decay time after cessation or decline in the volume of drug use and that significant reductions in resistance require equally significant reductions in drug consumption. These results highlight the need for early intervention once resistance is detected.     

Contextual community prevention theory: Building interventions with community agency collaboration.

Translation from research to practice faces numerous problems that include replicating effectiveness, fidelity to the protocol and processes, and adaptations to different types of target populations. Working collaboratively with existing service providers can speed up the time for development and can ease the implementation of empirical randomized trials. Contextual community prevention theory is an innovative approach that focuses on changing behaviors of community members by creating a visible institutional presence that draws and pulls the targeted population into the organization’s activities and interventions. The result is an institution or organization within the community that provides a new active and dynamic context, engaging its community members into its activities, interventions, and functions. An HIV prevention program developed collaboratively from the ground up for Latino gay/bisexual men is presented. Results from the program evaluation efforts across the years suggest promise for testing its efficacy through a randomized trial. HIV prevention efforts need to develop dynamic support systems within communities where these men have ownership, have control, and feel safe; otherwise HIV infection rates in this population will increase. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Epilogue: Psychological interventions in the changing health care systems.

Psychotherapy has utility for a wide variety of circumstances that have significant economic, personal, and social consequences. This special issue is a small attempt to address some of these problems. There are important omissions, such as the frequent use of psychotropic medications in psychotherapy, psychological rehabilitation of patients and families with chronic health problems, and hospice care. The need for establishment of a national policy on how psychotherapy can be used to create more effective and humane solutions to societal problems has been identified. The challenge is how to fund the study of health and other social problems responsive to psychotherapy. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Stroke in Melbourne. A study of the relationship between a teaching hospital and the community

A prospective study of stroke admissions to the Royal Melbourne Hospital was planned to provide baseline information before the introduction of Medibank. One hundred and seventy patients admitted consecutively over a six-month period were followed until either three months had elapsed since admission, or death had supervened. Although over half the cases (57%) came from areas close to the hospital, the remainder come from a wide area embracing most of suburban Melbourne. Of the cases expected from the local areas, less than one-third were admitted to the Royal Melbourne Hospital. Expected demand for admission to hospital from the north-west region was calculated and the dependence of the community upon the private sector demonstrated.     

Evolutionary relationship of uptake systems for biopolymers in Escherichia coli: cross-complementation between the TonB-ExbB-ExbD and the TolA-TolQ-TolR proteins

Escherichia coli possesses two energy-coupled import systems through which substances of low concentration and of a size too large to permit diffusion through the porins are translocated across the outer membrane. Group B colicins, ferric siderophores and vitamin B12 are taken up via the TonB-ExbB-ExbD, group A colicins via the TolA-TolQ-TolR system. Cross-complementation between the two systems was demonstrated in that tolQ tolR mutants transformed with plasmids carrying exbB exbD became sensitive to group A colicins, and exbB exbD mutants transformed with plasmid-encoded tolQ tolR became sensitive to group B colicins. TolQ-TolR interacted through TonB, and ExbB-ExbD interacted through TolA with the outer membrane receptors and colicins. Activity of ExbB ExbD via TolA was higher in cells lacking TonB, and activity of TolQ TolR via TonB was increased when TolA was missing. The very distinct TolA and TonB proteins mediate exclusive interaction with group A and group B receptors, respectively. ExbB-TolR and ExbD-TolQ mixtures showed little if any complementation of exbB exbD and tolQ tolR mutants indicating coevolution of ExbB with ExbD and TolQ with TolR. Sequence homology and mutual functional substitution of ExbB-ExbD and TolQ-TolR suggest the evolution of the two import systems from a single import system.     

Coercion in the community: issues for mature treatment systems

Coercion in community-based mental health treatment refers to much more than just court-ordered treatment. Mature systems can address these issues and adopt clinical approaches that decreased the need for coercion.     

A preliminary examination of the relationship between exposure to community violence and academic functioning.

Provides a preliminary examination of the relationship between exposure to community violence and academic functioning in a group of 45 African American children (aged 11–14 yrs) living in an impoverished urban environment. In addition, the role of family achievement expectations and religion, 2 previously identified family compensatory factors related to academic resilience, were evaluated as moderators of the relationship between community violence and academic functioning. Ss completed questionnaires about the variables mentioned above. Results suggest that exposure to community violence had a weak relationship with academic functioning in general, but that relationship was intensified under certain circumstances. Significant interactions between exposure to community violence, and both family achievement orientation and religious emphasis suggest that exposure to community violence may alter the role of previously identified compensatory factors. Children who perceived very high achievement expectations and a very strong moral-religious emphasis were most at risk for poor academic functioning as exposure to community violence increased, although children from these types of families displayed the highest academic functioning at lower levels of community violence exposure. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Behavioral interventions in resource conservation: A systems approach based on behavioral economics.

Outlines some of the advantages of an integration of psychological (social-learning) and economic conceptualizations when developing behavioral interventions in resource conservation. The procedures and results of rebate studies in residential energy and water conservation are presented in which rebates were used as a method to modify conservation behaviors and to estimate experimental price elasticity in contrast to the usual econometric methods. A meta-analysis is performed on behavioral energy studies conducted from 1973 to 1980, which shows that the effectiveness of rebates and feedback is partially explained by an economic factor. Also reviewed are field-based studies designed to modify perceptions of comfort and residential energy conservation in addition to the development of a rebate system instituted to reduce domestic water consumption. Maximization theory is offered as an integrative, conceptual framework that may be useful for planning resource conservation interventions. (49 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Preventive community interventions: Reducing school children's smoking and decreasing smoke exposure.

Preventive interventions directed toward (a) building strengths and competencies in individuals to prevent disorders and (b) modifying environmental irritants predisposing to pathology are high priority needs inherent within a community perspective. The present article reviews projects illustrating these 2 approaches. The 1st project deals with efforts to prevent and reduce rates of smoking in school youngsters. The 2nd series of studies focuses on documenting the extent of exposure to smoke in various naturalistic settings and investigating strategies to reduce this exposure. (24 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Community-based participatory research: Partnering with communities for effective and sustainable behavioral health interventions.

The present issue contains one of the first studies published in Health Psychology—by Resnicow and colleagues—that uses elements of community-based participatory research (CBPR) (Resnicow et al., 2009). The authors engaged community partners (three health maintenance organizations or HMOs) to develop and implement a fruit and vegetable promotion intervention (Tolsma et al., 2009). African American HMO patients (the intervention targets) participated in formative work (i.e., focus groups) on survey items and intervention content and in survey pilot testing. A diverse group of researcher and nonresearcher expert stakeholders (e.g., African American health plan staff; consultants with expertise in Black identity theory, on which the intervention was based) was engaged in major project decisions regarding the measures and intervention design. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Quantifying the effects of community mental health consultation interventions.

A review of 1,643 consultation outcomes through meta-analytic studies reveals a moderate overall mean effect for consultation interventions. Utility formulas demonstrate these consultation interventions will provide an 11% improvement in outcome measures of consultee and organizational functioning. While the empirical evidence of the efficacy of consultation interventions is very substantial, the acceleration of the rate of change and the increasing complexity of organizational functioning require continuous reconsideration of current conceptual models of consultation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Clarification of the relationship between free radical spin trapping and carbon tetrachloride metabolism in microsomal systems

It has been proposed that the C-phenyl-N-tert-butylnitrone/trichloromethyl radical adduct (PBN/.CCl3) is metabolized to either the C-phenyl-N-tert-butylnitrone/carbon dioxide anion radical adduct (PBN/.CO2-) or the glutathione (GSH) and CCl4-dependent PBN radical adduct (PBN/[GSH-.CCl3]). Inclusion of PBN/.CCl3 in microsomal incubations containing GSH, nicotinamide adenine dinucleotide phosphate (NADPH), or GSH plus NADPH produced no electron spin resonance (ESR) spectral data indicative of the formation of either the PBN/[GSH-.CCl3] or PBN/.CO2- radical adducts. Microsomes alone or with GSH had no effect on the PBN/.CCl3 radical adduct. Addition of NADPH to a microsomal system containing PBN/.CCl3 presumably reduced the radical adduct to its ESR-silent hydroxylamine because no ESR signal was observed. The Folch extract of this system produced an ESR spectrum that was a composite of two radicals, one of which had hyperfine coupling constants identical to those of PBN/.CCl3. We conclude that PBN/.CCl3 is not metabolized into either PBN/[GSH-.CCl3] or PBN/.CO2- in microsomal systems.     

Sensoristrain: an exploration of nursing interventions in the context of the Neuman systems theory

Platelet-activating factor (PAF), identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, exhibits potent proinflammatory properties. PAF is produced by numerous cell types, including endothelial cells, neutrophils, monocytes, macrophages, basophils, eosinophils and mastocytes. Since the discovery and identification of the chemical structure of PAF, a large variety of specific PAF-receptor antagonists, both natural and synthetic compounds, have been described. Intensive research has been conducted and development programs set up by more 25 pharmaceutical companies world-wide, studying the therapeutic interest of more than 50 PAF-receptors antagonists in various pathophysiological conditions. Medline (1966-1996), Embase (Excerpta Medica; 1974-1996), and other biomedical and drug directory databases were searched to identify English-language articles (basic science, clinical trial research, and review articles) and abstracts of conference proceedings on PAF receptor antagonists and related terms. The most important PAF receptor antagonists are reviewed with their effectiveness in various experimental tests. Fundamentally, PAF antagonists may be divided in two groups: natural and synthetic compounds. Natural (Ginkgolides, Kadsurenone, Chantancin, Phomactin, Swietemohonin A, Prehispalone, THC-7-oic acid, Aglafoline, FR 900452, PCA 4248 and SCH 37370), and synthetic antagonists (CV-3988, CV-6209, SRI 63-072, SRI 63-441, UR-10324, UR-11353, E-5880, CL 184005, 6-Mono and Bis-aryl phosphate antagonists, TCV-309, Ro-74719, WEB 2086, Y 24180, BN 50726, BN 50727, BN 50730, BN 50739, Ro 24-4736, Ro 24-0238, RP 55778, RP 59227, RP 66681, YM 264, YM 461, SM 10661, SR 27417, UK 74505, BB 182, BB 823, BB 654, SDZ 64-412, SDZ 65-123, L 652731, L 659898, L 668750, L 671284, L680573, L 680574, CIS 19, ABT-299 and Pinusolide) have a great variability in their chemical structure that might have importance in their different pharmacological profile. The great majority of these drugs are under development, and only a few have undergone clinical trials.     

New insights and interventions: churches uniting to reach the African American community with health information

Effective church-based community health programs must take a holistic approach when dealing with health problems among African Americans. Such an approach emphasizes the relationship between the physiological, psychological, and spiritual selves. These programs must also ensure the complete involvement of clergy and church members, who can participate in programs by providing a certain level of skill, thereby engendering a sense of partnership in the process. Also necessary is an emphasis on healthy living instead of a fear of dying. Rather than framing health issues in mortality statistics, church-based programs need to stress ways to improve the quality of life, in keeping with the messages conveyed by the church. By taking these approaches, health organizations will find a religious community more willing to accept health messages.     

Planning and evaluating strategies for AIDS health education interventions in the Muslim community in Uganda

In 1992 the Islamic Medical Association of Uganda designed an AIDS prevention project. A baseline survey was conducted to assess prevailing knowledge, attitudes, and practices among the Muslim communities in two districts. A low rate of incorrect beliefs about HIV transmission was found, although gaps in knowledge remain, particularly regarding vertical transmission and asymptomatic HIV infection. Less than 10% knew that condoms can protect against HIV transmission. Lack of knowledge was documented regarding the risk of HIV transmission associated with practices common in the Islamic community, such as polygamous marriages, circumcision, and ablution of the dead. The AIDS prevention project has incorporated specific messages and interventions as a result of these findings.     

Family systems and alcohol misuse: Research on the effects of alcoholism on family functioning and effective family interventions.

This article reviews the most prominent research at the interface between studies of alcohol addiction and family systems psychology. The review addresses the general effects of alcohol misuse on family functioning as determined in empirical studies comparing healthy families, alcohol afflicted families, and otherwise troubled families. Three factors ("dry" vs "wet" families, family development and the progression of alcoholism, and family structure) are identified as particularly relevant to understanding the treatment needs of families affected by alcohol misuse. Research examining the general efficacy of family interventions in the treatment of alcoholism and specific treatment considerations unique to treating families coping with alcohol misuse are reviewed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Longitudinal analysis of the relationship between changes in smoking and changes in drinking in a community sample: The Winnipeg Health and Drinking Survey.

Smoking cigarettes and drinking alcohol are positively correlated in cross-sectional studies of the general population. However, it is unclear whether changes in quantity of drinking over time are related to changes in amount of smoking over time. This investigation examined, with structural equation modeling, the relationship of changes in drinking to changes in smoking over 2 years among 344 adults who reported cigarette smoking and alcohol use at baseline in 1989-1990 or at follow-up in 1991-1992 or both. Surprisingly, no significant relationships were found between changes in smoking and changes in drinking. This lack of effect suggests that changes in the quantity or intensity of drinking and of smoking are not related in any important way in nonclinical populations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Gordin Kaplan Award Lecture. Building a relationship: science and the community

An appreciation for the intrinsic relationship that exists among science, scientists, and the public must be established. Both practitioners of science and the public should be made more aware that science is part of everyday life and that the definition of a scientist should be more encompassing. It is generally accepted that the public supports but often does not understand the goals of the scientific community. This is often due to lack of effective communication. The scientific community has accepted accountability to the public and attempts have been made to improve our image. Programs by groups and individuals to interact with the public, particularly school children, have grown. However, there is still a need to expand this area. It is our responsibility to find our niche in science awareness programs as speakers, mentors, or facilitators. Participation in these programs is an essential part of a professional scientist's career and should be encouraged by administration. Interaction with the public improves our ability to explain science in lay terms and the relevance of our work to the community. End points should be established to measure success: not just numbers of students entering "scientific" careers but also science literacy. Developing this strategy will not only improve the image of the scientific community with the public but also build a lasting relationship where needs and aspirations will be mutually appreciated.