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The isolation rate for Salmonella enterica serotype Enteritidis (SE) in humans in the United States of America (USA) increased from 1,207 sporadic isolates identified in 1976 (0.6 isolates/100,000 population) to 10,201 identified in 1995 (4.0/100,000 population). The proportion of reported Salmonella isolates which were SE increased from 5% to 25% during the same time period. In 1990, 1994, and 1995, SE was the most commonly reported reported Salmonella serotype in the USA. Much of this increase has been associated with the consumption of contaminated shell eggs. An examination of the results of a United States Department of Agriculture (USDA) survey of spent hens at slaughter and unpasteurised liquid egg at breaker plants (liquid egg processors) in 1991 and 1995 reveals an increase in the prevalence of SE isolates overall and in most regions of the USA. SE phage type 4 (pt 4), the predominant SE phage type in other parts of the world, has emerged in the egg industry in the western USA concurrent with a sharp increase in the number of sporadic human SE pt 4 isolates in California and Utah. Research on the molecular structure and virulence of SE pt 4 isolates from the USA as compared with isolates from other parts of the world (human and poultry) should be a priority. A comparison of DNA from pt 4 isolates from the USA and Europe may provide information about the potential threat to public health and poultry in the USA from this phage type. Some regional success in the reduction of human illness as a result of SE control efforts is apparent. The Pennsylvania Egg Quality Assurance Program has shown progress in reducing SE infection in participating flocks. At a national level, however, neither the incidence of human illness due to SE nor the prevalence of SE in flocks and unpasteurised liquid eggs have decreased significantly, despite the implementation of the USDA 'trace back' regulation from 1990 to 1995, and intensified efforts to educate food handlers and to enforce safe food handling practices. More effort is needed to control SE at every stage of the egg continuum, from production through to consumption. A risk-reduction approach, with barriers to the introduction and multiplication of the pathogen throughout the farm-to-table continuum, is the most practical method for reducing human illness from SE in shell eggs at present. An effective long-term solution will require interdisciplinary efforts involving government, industry, consumers, and academics. Interventions should be developed and evaluated in compliance with the potential for reducing the risk to human health and cost-effectiveness.  相似文献   

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BACKGROUND: Fluoroquinolones are one of the most widely used treatments for gonorrhoeae. Changes in the susceptibility of Neisseria gonorrhoeae to these agents may threaten their use. GOAL OF THIS STUDY: To report several resistant strains (>1 mcg/ml) isolated in the western United States and to evaluate the prevalence of strains with reduced susceptibility (ofloxacin 0.25 mcg/ml, ciprofloxacin 0.06 mcg/ml). STUDY DESIGN: The microbiology and epidemiology of three resistant strains were characterized and 12,761 other strains were evaluated for fluoroquinolone susceptibility as part of the Gonococcal Isolate Surveillance Project of the Centers for Disease Control and Prevention. RESULTS: Fluoroquinolone-resistant strains may appear sporadically. The prevalence of isolates with reduced susceptibility to fluoroquinolones remains low in the Southwest region of the United States. CONCLUSIONS: Continued active surveillance is needed to detect and control the spread of quinolone-resistant Neisseria gonorrhoeae.  相似文献   

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Tick-borne diseases in the United States   总被引:1,自引:0,他引:1  
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NJ Nusbaum 《Canadian Metallurgical Quarterly》1997,336(8):583; author reply 584-583; author reply 585
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Leishmaniasis is a recurrent health problem for the U.S. and other militaries. Health care workers may be unfamiliar with the risk factors, transmission, clinical features, diagnosis, and treatment of this disease. A team of highly trained specialists is required to properly manage service members with leishmaniasis. Such care is available only in a few medical centers. Although there are no prophylactic drugs to prevent this disease, control of insect populations and use of personal protection measures can minimize arthropod-related casualties. The impact of leishmaniasis on military operations and research initiatives to better prevent, diagnose, and treat infection are discussed.  相似文献   

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Child care in the United States today   总被引:1,自引:0,他引:1  
This article describes the consumers and providers of child care in the United States. It uses data from nationally representative surveys and research studies conducted from the late 1960s through 1995 to examine the child care arrangements parents select for their young children, comparing today's arrangements with those made by parents decades ago. It then discusses the availability of child care, examining both the number of child care spaces available and whether quality programs are available to suit the needs and resources of parents. The article concludes with speculation about how proposed new policies and continuing trends may lead to future changes in child care.  相似文献   

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Problems in collection of uniform data on health education manpower on a continuing basis are discussed. Sources of data on current health education manpower projections for future needs are reviewed. Possible directions for improving manpower planning in this field are cited.  相似文献   

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Peroxidase-catalysed reactions are being analysed at an increasingly advanced level of structural and mechanistic sophistication. A significant development in this respect has been the long-anticipated solution of crystal structures for several plant peroxidases and a fungal peroxidase complexed to benzhydroxamic acid. New insights into peroxide binding and catalysis have been obtained through site-directed mutagenesis, a technique also crucial to recent progress in understanding the diversity of substrate interaction sites associated with peroxidases from different sources.  相似文献   

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The organizations to which psychologists belonged at the turn of the 20th century were identified. The attributes of the meetings and the membership of those organizations were compared and discussed. In addition to the American Psychological Association, psychologists belonged to the American Philosophical Association and the American Association for the Advancement of Science as well as to local and regional organizations. In addition, some psychologists belonged to the Society of Experimental Psychology, but membership in that organization was by invitation only. The topics presented at the meetings of the psychological and philosophical associations often were identical or very similar, and the clear disciplinary separation that is typical in 2000 was rare in 1900. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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Describes the origins and history of engineering psychology noting the successes: (1) Explosive expansion and growth, (2) a wide range of research efforts and engineering applications, (3) interest and acceptance by engineering associates, (4) an increasing number of graduate training programs in departments of psychology as well as schools of engineering, and (5) general benefits to psychology as a science and profession. The deficiencies in engineering psychology are attributed to too great an involvement between art and science. (20 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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On a global basis, the steel industry is shrinking and restructuring. In the industrialized world, consisting of the United Stales, Japan, and Western Europe, a total of 100 million tons of steelmaking capacity have been abandoned. Conversely, the Third World is adding steel capacity. Mainland China, South Korea, Taiwan, and Brazil are expanding rapidly. However, the total amount to be added in these countries in the next two years is by no means enough to compensate for the shrinkage in the industrialized world.

The restructuring process in Japan, the United States, and Western Europe consists of four steps:

1) steel plant closures

2) mergers of steel companies

3) joint ventures between companies, both domestic and international

4) diversification into non-steel activities.

In Japan, the major companies are engaging in joint ventures with some companies in the United States, Indonesia, and Brazil. They are also entering other fields such as electronics and ceramics, In Europe, overall plans have systematically reduced capacity in the EEC countries and more is in store.

In the United States, there have been many plants closed, reducing capacity by more than 35 million tons. One major merger of Republic and LTV resulted in LTV Steel. A number of joint ventures have taken place among domestic companies and between domestic and foreign companies, and there has been considerable activity in moving into non-steel areas such as oil and gas.  相似文献   

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While the infrastructure in the United States is in need of large and immediate investment, the funds provided by public agencies are not nearly sufficient to face such a challenge. Build-operate-transfer (BOT) is a delivery/financing system that can be a solution to this problem. In this system, a private sponsor finances the design, construction, maintenance, and operation of a public project for a specified concession period, at the end of which it transfers ownership to the government agency, hopefully after recouping its costs and achieving profits. A questionnaire survey of large municipalities and state departments of transportation was conducted to determine the extent to which they are using BOT in their large projects, to investigate the implementation of BOT, and the reasons why some government agencies avoid using BOT. The findings indicate that very few agencies use BOT. The reasons why most do not use BOT were reported by the respondents to be the availability of proven alternatives and enough funds, the existence of political barriers, and resistance to change both on the part of government agencies and private sponsors. When government agencies and private sponsors explore the use of BOT, they should avoid the pitfalls perceived by the respondents in this study.  相似文献   

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There are "at least 1,000 psychologists today, as compared with less than two dozen some 30 years ago, who devote full time to employment in industry." Their activities are diverse and are discussed under the following major headings: Personnel Selection (Employee selection and assignment, Executive selection, Criterion research); Personnel Development (Appraisal, Employee training, Management development, Counselling); Human Factors in Design (Equipment design, Product design); Productivity; Management; and Miscellaneous. "Psychologists are performing a variety of functions for industry. No one person is engaged in all of these activties." (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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