共查询到18条相似文献,搜索用时 62 毫秒
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综述了近年来离子液体作为反应介质在Suzuki偶联、Heck偶联、Sonogashira偶联、碳-杂原子交叉偶联和Negishi偶联等反应中的研究进展。 相似文献
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离子液体作为一种新型绿色溶剂,具有许多独特的物理化学性质,近年来逐渐被人们所认知,并发现可用在许多重要领域.本文简单介绍离子液体的种类和特点,重点介绍在咪唑类离子液体中的Michael、Heck、Suzuki、Witting、Baylis-Hillman和Aldol等重要的C-C偶联反应. 相似文献
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Dong‐Hwan Lee Young‐Jun Kwon Myung‐Jong Jin 《Advanced Synthesis \u0026amp; Catalysis》2011,353(17):3090-3094
This communication reports on the β‐diketiminatophosphane palladium‐catalyzed copper‐free Sonogashira coupling of aryl chlorides with alkynes. A catalyst loading of 0.5 mol% is sufficient to achieve high performance under relatively mild reaction conditions. Furthermore, dialkynylbenzenes are efficiently prepared by one‐pot double Sonogashira couplings of aryl dichlorides. 相似文献
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A mixture of Na2PdCl4, CuI and (t‐Bu)3PH+BF4− (molar ratio 4 : 3 : 8) dispersed in H2N(i‐Pr)2+Br− can be used as a “single source” precatalyst for the Sonogashira coupling of aryl bromides with various aryl‐ and alkylacetylenes in HN(i‐Pr)2 solvent. Arylacetylenes require just 0.005 mol % of Pd catalyst at 80 °C, with TOFs ranging between 3,200 and 10,000 h−1. 相似文献
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介绍了烷基化催化剂的特点及发展历程,概述了离子液体催化剂的分类和优点,讨论了离子液体催化烷基化的研究情况,包括异构烷烃与烯烃烷基化和芳香烃烷基化,最后,展望了离子液体催化剂在烷基化反应中的应用前景。 相似文献
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Victor Sans Anna M. Trzeciak Santiago Luis Józef J. Ziółkowski 《Catalysis Letters》2006,109(1-2):37-41
Efficient cross-coupling and carbonylative coupling of terminal alkynes with aryl iodides catalyzed by PdCl2(P(OPh)3)2 in the presence of NEt3 in toluene and in ionic liquids is described. In imidazolium ionic liquids, [bmim]PF6 or [mokt]PF6 (bmim = 1-butyl-3-methyl imidazolium cation, mokt = 1-methyl-3-octyl imidazolium cation) catalyst was recycled and used in
four concecutive catalytic cycles with high activity. In the absence of aryl iodide the same catalytic system catalyzed head-to-tail
dimerization of phenylacetylene to the 1,3-diphenyl enyne, trans-PhC ≡ C–C(Ph)=CH2, with a yield of 85%. 相似文献
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Sonogashina偶联法合成芳基末端炔的工艺改进 总被引:1,自引:0,他引:1
以对二溴苯(Ⅰa)、1,3,5-三溴苯(Ⅰb)和2-甲基-3-丁炔-2-醇(Ⅱ)为原料,在PdC l2、PPh3和CuI的催化作用下进行Sonogash ina偶联反应,偶联产物在KOH作用下发生消去反应,分别得到对溴苯乙炔(Ⅳa)、对二乙炔基苯(Ⅳa′)、1,3,5-三乙炔基苯(Ⅳb)。研究发现,在合成中间体1,4-二(3-羟基-3-甲基-1-丁炔)苯时,选择n(Ⅰa)∶n(Ⅱ)=1∶3较为适合;共催化剂n(CuI)∶n(Ⅱ)≈0.01时产率较高;水对偶联反应无影响。粗产物经硫酸铜溶液萃取、硅胶过滤、重结晶、真空升华进行分离提纯得到纯产品。3种产物的收率分别为75%、72%、70%。产物用IR、GC-MS、1HNMR进行了确证。 相似文献
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In the multi-functionalized ionic liquid compositions (MFILC), composed of 1-n-butyl-2-diphenylphosphino-3-methylimidazolium
hexafluorophosphate, [BDPPMIM]PF6), 1-(2-piperid-1-yl-ethyl)-3-methylimidazolium hexafluorophosphate, [PEMIM]PF6), and 1-n-butyl-3-methylimidazolium
hexafluorophosphate ([BMIM]PF6), PdCl2 served as an efficient catalyst for Heck reactions of aryl iodides and bromides. The
built-up PdCl2-MFILC, including stoichiometrically consumed base of [PEMIM]PF6, could be reused at least for seven cycles
without activity loss.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
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《分离科学与技术》2012,47(10):2205-2223
Abstract Separations of dispersions formed by mixing immiscible organic room‐temperature ionic liquids (IL)/hydrocarbon/and aqueous systems using a centrifugal solvent‐extraction contactor have been successfully demonstrated in proof‐of‐concept testing. This accomplishment is significant in that physical property factors that are typical of ionic liquid systems (e.g., similar densities of the bulk phases, low interfacial tensions, and high viscosities) are typically unfavorable for dispersion separation, particularly in continuous processes. Efficient separation of dispersions containing ionic liquid solvents is essential for utilization of these compounds in liquid‐liquid extraction applications to maximize both solute transfer efficiency and solvent recovery. Efficient solvent recovery is of particular concern in IL applications because of the high cost of most IL solvents. This paper presents the results of initial experiments with three hydrophobic ionic liquids to determine how their physical properties affect phase mixing and phase disengagement in contact with an aqueous solution using a centrifugal contactor. While the results of the reported work are promising, additional work is needed to optimize existing mathematical models of contactor hydraulics to address special considerations involved in IL‐based processes and to optimize the equipment itself for IL applications. 相似文献