Semantic processing in the right hemisphere may contribute to drawing inferences from discourse

After listening to multiple-episode stories that promoted coherence inferences, right hemisphere-damaged patients answered Inference questions about the stories less accurately than Explicit questions, whereas normal elderly subjects answered both question types equally well. In addition, while subjects listened to the stories they made lexical decisions to tests words that were related to the promoted inferences or were unrelated to the stories. Right hemisphere-damaged patients responded more slowly to inference-related words than to unrelated words, whereas normal elderly subjects responded more quickly to interference-related words than to unrelated words. Furthermore, the episode boundaries did not affect either group's accuracy on Inference questions, and the boundaries equally affected both groups' lexical decision latencies, suggesting that the patients' inferencing deficit was not due to an impairment in organizing the mental substructures used to represent discourse. These results suggest that the right hemisphere-damaged patients lacked activation of semantic information necessary for drawing coherence inferences.     

Semantic ambiguity resolution in positive schizotypy: A right hemisphere interpretation.

Positive schizotypal traits have been associated with right hemisphere activation. Previous research has indicated that the left and right hemispheres differ in their processing of semantic ambiguity; specifically, given sufficient time, the left hemisphere primes dominant meanings and inhibits subordinate meanings, and the right hemisphere primes both dominant and subordinate meanings. The authors examined whether individuals who differed in positive schizotypy demonstrated different patterns of priming on a semantic ambiguity task, reflective of differences in hemispheric activation. Individuals low in schizotypy demonstrated the expected pattern of priming the dominant meaning while inhibiting the subordinate meaning. Individuals high in schizotypy demonstrated similar priming of the dominant meaning but no inhibition of the subordinate meaning. The role of this failure of inhibition in the generation of schizotypal thought is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Consonant and vowel production of right hemisphere patients

Recent reports of subclinical phonetic deficits in posterior and most particularly in Wernicke's aphasics have challenged the traditional dichotomy which characterized speech deficits in aphasia as anterior/phonetic and posterior/phonological. It is unclear whether the basis of the phonetic deficit in posterior aphasics reflects the fact that the speech production system extends to more posterior regions of the left hemisphere than previously thought or alternatively is the result of generalized brain damage effects. The present study explores the latter possibility by investigating the patterns of speech production in right hemisphere brain-damaged, non-aphasic patients with anterior and posterior lesions. Acoustic analyses conducted on a range of consonant and vowel parameters showed differences between the speech patterns of both anterior and posterior right hemisphere patients and that of Wernicke's aphasics. These findings suggest that the subclinical deficit of Wernicke's aphasics can not simply be ascribed to a generalized brain-damage effect and raise the possibility that the right hemisphere also plays some role, if only a minor one, in the phonetic implementation of speech.     

Evidence for deficits on different components of theory of mind in Huntington's disease.

Objective: The main aim of this study was to investigate the effects of Huntington's disease (HD) on cognitive and affective Theory of Mind (ToM) abilities. The relation of ToM performance and executive functions was also examined. Method: Eighteen HD patients, early in the course of the disease, and 18 healthy volunteers matched for age and educational levels, were given two tasks: a nonverbal cognitive ToM task assessing attribution of intentions to others and a revised version of the 'Reading the Mind in the Eyes' test, which is an affective ToM task assessing the understanding of other people's mental states from their eyes. Participants were also given various executive tests. Results: The two ToM tasks revealed a significant impairment of ToM abilities in HD patients. Executive functioning was impaired in the HD group and ToM performance on the attribution of intentions task was dependent on several executive processes. Conclusions: Our results are consistent with the idea that both cognitive and affective aspects of ToM could be impaired in HD patients, indicating that cortico-subcortical circuits are underlying higher social functions such as ToM. The results are also consistent with the idea that only a few executive mechanisms regulate the ToM abilities we tested in this work. They also provide a basis for the understanding of the disorganized behavior and the breakdown of interpersonal relationships in daily life after HD. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Humor and suicide: Favorite jokes of suicidal patients.

During an interview 20 patients who had attempted suicide and 20 matched nonsuicidal patients were asked to relate their favorite joke. Jokes were told by 12 attempters and 9 controls. 2 raters, blind to the purpose and nature of the study, rated each joke for direction of punishment expressed in the themes. Based on the combined chi-square probabilities associated with ratings by the 2 judges, suicidal Ss told significantly more jokes with a self-punishing theme than did nonsuicidal controls. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sex and the single hemisphere: specialization of the right hemisphere for spatial processing

Specialization of the right hemisphere for spatial processing was studied in 200 normal boys and girls between 6 and 13 years of age. Boys performed in a manner consistent with right hemisphere specialization as early as the age of 6. Girls showed evidence of bilateral representation until the age of 13. The results suggest a sexual dimorphism in the neural organization underlying cognition during a major period of childhood. The results, which have implications for reading instruction, are discussed in terms of a possible sex difference in neural plasticity during development and the clinical consequences of such a difference.     

Visual imagery training for patients with visual perceptual deficits following right hemisphere cerebrovascular accidents: A case study presenting the Lighthouse Strategy.

Objective: To illustrate use of the Lighthouse Strategy (LHS) to improve visual neglect. Study Design: Single case design with repeated measures on 2 dependent variables, a posttest, and a follow-up. Setting: Inpatient Brain Injury Rehabilitation Unit, Subject: A 65-year-old Caucasian woman with left visual inattention following a right-hemisphere stroke. Intervention: Patient learned to use the LHS during 3 treatment sessions. Main Outcome Measures: Pre- and posttreatment scores on the Mesulam Verbal Cancellation Test, Cross Drawing, posttreatment route-finding task, postdischarge telephone follow-up. Results: Error-free posttreatment performances on all measures. Continued functional use of the LHS 1 month after discharge. Conclusions: The LHS can be efficiently taught and promotes functional improvements in patients with visual neglect. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Immediate and delayed responses from memory in brain-damaged patients.

Hypothesized that brain-damaged (bd) patients perform more poorly than non-brain-damaged (nbd) patients on both immediate and delayed memory tasks and that the difference is greater on the delayed memory tasks. 24 bd and 24 nbd psychiatric patients were administered a 15-design multiple choice version of the benton visual retention test. Results support earlier findings that memory performance is susceptible to brain damage, but questions its relevance in specifying the 2 different memory functions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex

Spatial memory tasks, performance of which is known to be sensitive to hippocampal lesions in the rat, or to medial temporal lesions in the human, were administered in order to investigate the effects of selective damage to medial temporal lobe structures of the human brain. The patients had undergone thermo-coagulation with a single electrode along the amygdalo-hippocampal axis in an attempt to alleviate their epilepsy. With this surgical technique, lesions to single medial temporal lobe structures can be carried out. The locations of the lesions were assessed by means of digital high-resolution magnetic resonance imaging and software allowing a 3-D reconstruction of the brain. A break in the collateral sulcus, dividing it into the anterior collateral sulcus and the posterior collateral sulcus is reported. This division may correspond to the end of the entorhinal/perirhinal cortex and the start of the parahippocampal cortex. The results confirmed the role of the right hippocampus in visuo-spatial memory tasks (object location, Rey-Osterrieth Figure with and without delay) and the left for verbal memory tasks (Rey Auditory Verbal Learning Task with delay). However, patients with lesions either to the right or to the left hippocampus were unimpaired on several memory tasks, including a spatial one, with a 30 min delay, designed to be analogous to the Morris water maze. Patients with lesions to the right parahippocampal cortex were impaired on this task with a 30 min delay, suggesting that the parahippocampal cortex itself may play an important role in spatial memory.     

Visuospatial difficulties and clumsiness: on the interpretation of conjoined deficits

Sixteen children with motor difficulties and 16 controls, matched on age, gender and verbal I.Q., were assessed on the Test Of Motor Impairment, various graphic tasks and a measure of visuospatial discrimination. Poor perceptual and motor performance tended to co-occur but contrary to the visuospatial deficit account of clumsiness these abilities were uncorrelated even when attention was restricted to the less proficient children. There was no tendency for the control group's superiority in graphic reproduction to diminish when visual feedback was withheld. Some suggestions are offered concerning more appropriate methods for framing and testing causal deficit hypotheses.     

Executive function and theory of mind: Predictive relations from ages 2 to 4.

Despite robust associations between children's theory of mind (ToM) and executive function (EF) skills, longitudinal studies examining this association remain scarce. In a socially diverse sample of 122 children (seen at ages 2, 3, and 4), this study examined (a) developmental stability of associations between ToM, EF, verbal ability, and social disadvantage; (b) continuity and change in ToM and EF; and (c) predictive relations between ToM and EF. Verbal ability and social disadvantage independently predicted changes in EF (but not ToM). Task scores improved with age and showed stable individual differences. The authors examined predictive relations between ToM and EF using partial correlations (controlling for age and verbal ability) and hierarchical regressions (that also controlled for social disadvantage and initial ToM and EF). The findings provide only partial support for the view that ToM is a prerequisite for EF but stronger support for the proposal that EF facilitates children's performance on ToM tasks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Developing organization of mental verbs and theory of mind in middle childhood: Evidence from extensions.

[Correction Notice: An erratum for this article was reported in Vol 34(5) of Developmental Psychology (see record 2008-09591-001). In this article, Figures 2 and 4 were inadvertently switched. The figure appearing on page 519 is Figure 4, and the data pertain to third graders; the figure appearing on page 521 is Figure 2, and the data pertain to adults.] The purpose of the study was to assess developments in the theory of mind suggested by changes in the organization of cognitive verb extensions during the elementary school years. Adults and 3rd- and 5th-grade children were provided with a set of mental activity scenarios and were asked to select the best verbs from a list of cognitive verbs that might apply to each scenario. Changes in organization were assessed by examining overlapping uses of cognitive verbs in different contexts. There were 3 major changes with development: (a) the understanding of the role of memory in input functions increased, (b) the interrelatedness of memory- and comprehension-related verbs increased, and (c) the importance of cognitive certainty and uncertainty engaged by constructive processing verbs increased. Together, these findings suggest that a constructivist theory of mind develops in later childhood. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Activation without selection: parallel right hemisphere roles in language and intentional movement?

Because language and praxis each require the activation and selection of knowledge structures in long-term memory (MacKay, 1985, 1987), it is reasonable to consider whether hemisphere asymmetries for such processes span both domains. Language and skilled movement are thought to be strongly lateralized to the left hemisphere in most individuals. Yet, although recent evidence suggests that the right hemisphere also contributes to language use in context, few similar arguments have been made for the right hemisphere's involvement in motor planning. In this paper, we review some of the evidence for a right hemisphere role in language and action processing and propose that within each domain the right hemisphere activates a range of relevant knowledge structures without selection.     

Selective attentional processing and the right hemisphere: Effects of aging and alcoholism.

Thirty-seven nonalcoholic individuals (22 women, 15 men), ages 26–76, and 36 abstinent alcoholic individuals (11 women, 25 men), ages 31–74, participated in a cued-detection task that assessed right hemisphere (RH) functioning associated with aging and alcoholism. Young controls were less reliant on cues following RH activation, which is consistent with the view that the RH has an advantage because it has the ability to attend to a broader spatial array than does the left hemisphere (LH). This RH advantage was not obtained in older controls or alcoholic participants. The pattern of results for the older nonalcoholic participants indicated that they neither benefited from valid cues following LH activation, nor exhibited enhanced processing on invalid cue trials following RH activation. The results for the alcoholic participants were consistent with RH functional decline, but did not support the view that alcoholism and aging have synergistic effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Language experience and right hemisphere tasks: the effects of scanning habits and multilingualism

This study explores the effects of multilingualism and reading scanning habits on right hemisphere (RH) abilities. Native Hebrew speakers and Arabic-Hebrew bilinguals performed three tasks. Experiment 1 employed an odd/even decision paradigm on lateralized displays of bar graphs. Both groups of subjects displayed the expected LVFA within the range previously reported for readers of English. Experiment 2 consisted of a chair identification task designed to tap asymmetry of hemispheric arousal and a chimeric face task designed to tap RH specialization for facial emotion. Neither scanning habits nor language experience affected performance on the chair task. Scanning habits seem to have affected performance on the chimeric faces task: there was no preference for the left smile in these right-to-left readers, as opposed to previous results in the literature using left-to-right readers. Correlations between measures from the three tasks and all the subject's scores on an English proficiency test and on a Hebrew test for the bilinguals reveal tentative relationships between proficiency in a second language and RH abilities. The results do not support the hypothesis that multilingualism can affect the manner in which these nonlanguage tasks are subserved by the RH. They do support the hypothesis that scanning habits particular to specific languages can affect performance asymmetries on some nonlanguage tasks that have been posited to reflect RH specialization.     

Language access and theory of mind reasoning: Evidence from deaf children in bilingual and oralist environments.

This investigation examined whether access to sign language as a medium for instruction influences theory of mind (ToM) reasoning in deaf children with similar home language environments. Experiment 1 involved 97 deaf Italian children ages 4-12 years: 56 were from deaf families and had LIS (Italian Sign Language) as their native language, and 41 had acquired LIS as late signers following contact with signers outside their hearing families. Children receiving bimodal/bilingual instruction in LIS together with Sign-Supported and spoken Italian significantly outperformed children in oralist schools in which communication was in Italian and often relied on lipreading. Experiment 2 involved 61 deaf children in Estonia and Sweden ages 6-16 years. On a wide variety of ToM tasks, bilingually instructed native signers in Estonian Sign Language and spoken Estonian succeeded at a level similar to age-matched hearing children. They outperformed bilingually instructed late signers and native signers attending oralist schools. Particularly for native signers, access to sign language in a bilingual environment may facilitate conversational exchanges that promote the expression of ToM by enabling children to monitor others' mental states effectively. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Culture and ideology in Ian Suttie's theory of mind.

The author discusses the comprehensive outlook that shaped Ian Suttie's psychology. Suttie is seen as a background influence behind the British school of psychoanalysis, and his ideas pervade that school and therefore late-modern notions of the mind. The author describes the formation of Suttie's independent theory, and argues that his project was expressly ideological, as he tried to counter what he saw as the reactionary and disruptive influence of Freud's classical theory. Suttie offered an optimistic perception of the mind, which could serve as the basis for a progressive social policy. This perception was rooted in the outlook of early 20th-century reforming liberalism, whose preferences and prejudices it shares. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Microgenetic analysis of word associations in schizophrenic and brain-damaged patients.

Associations to the Kent-Rosanoff list of words were categorized as being "mature" or "immature" following the schema outlined by previous research (see 33: 8338). In that research, some support was found for the hypothesis that schizophrenics respond in a more "immature" manner than normals. The present study repeats the former one, adding a second group for comparison (a group of organics) in addition to the control group of normals. The results did not support the former study. Organics were found to be perseverative in "meaningful" responses to the word stimuli, but not to repeat irrelevant ones. From Psyc Abstracts 36:04:4JQ64M. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social interaction skills and theory of mind in young children.

Two studies explored relations between peer social skills and theory of mind in young children. In Study 1, a global teacher rating of social skills with peers, performance on a traditional false-belief task, a standardized assessment of auditory language comprehension, and a time sampling of amount of speech with peers were obtained. Positive, but moderate, zero-order correlations were observed between the false-belief measure and social skills, and false belief accounted for a significant amount of additional variance in social skills after covarying age and the 2 measures of language. Study 2 replicated the findings of Study 1 by using a larger sample and a standardized teacher questionnaire. The results are discussed with regard to the critical role of a mentalistic theory of behavior for human social interactions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The relation between individual differences in fantasy and theory of mind

The relation between early fantasy/pretense and children's knowledge about mental life was examined in a study of 152 3- and 4-year-old boys and girls. Children were interviewed about their fantasy lives (e.g., imaginary companions, impersonation of imagined characters) and were given tasks assessing their level of pretend play and verbal intelligence. In a second session 1 week later, children were given a series of theory of mind tasks, including measures of appearance-reality, false belief, representational change, and perspective taking. The theory of mind tasks were significantly intercorrelated with the effects of verbal intelligence and age statistically controlled. Individual differences in fantasy/pretense were assessed by (1) identifying children who created imaginary characters, and (2) extracting factor scores from a combination of interview and behavioral measures. Each of these fantasy assessments was significantly related to the theory of mind performance of the 4-year-old children, independent of verbal intelligence.