50%多菌灵·乙霉威可湿性粉剂的高效液相色谱测定

利用反相高效液相色谱外标法测定了50%多菌灵·乙霉威可湿性粉剂中多菌灵和乙霉威的含量。结果表明:方法的标准偏差分别为0.0495和0.0574;变异系数分别为0.19%和0.23%;平均回收率分别为99.86%～100.02%和99.32%～100.16%。     

25％福美双·克百威·萎锈灵悬浮种衣剂液相色谱分析

本文采用高效液相色谱法,以C18为固定相,甲醇＋水为流动相,用紫外检测器定量测定混荆中福美双、克百威和萎锈灵的含量。本方法的变异系数分别为O．11％、0．01％、0．03％;标准偏差分剐为0．013、0．007、O．021;平均回收率分剐为99．35％、99．17％、99．60％;线性相关系数分别为0．9996、0．9989、O．9994。     

50%福·甲·稻可湿性粉剂的液相色谱分析

论述了在同一液相色谱条件下测定50％福．甲．稻可湿性粉剂中的福美双，甲霜灵，稻瘟灵含量的方法。本方法采用反相色谱柱分离，四元混合流动相进行洗脱，紫外可变波长检测器进行检测，以外标法定量。福美双，甲霜灵和稻瘟灵的回收率分别为99．1％－100．89％、98．05％－101．32％，97．85％－101．82％，线性相关系数分别为0．9987，0．9987，0．9996，0．9977。     

24%甲·福可湿性粉种衣剂的液相色谱分析

论述了在同一液相色谱条件下测定定24％甲·福可湿性粉种衣剂中的甲霜灵、福美双含量的方法。本方法采用反相色谱柱分离,三元混合流动相进行洗脱,紫外可变波长检测器进行检测,以外标法定量。甲霜灵和福美双的变异系数分别为0．41％、1．60％;回收率分别为97.92％～101, 25％和99．03％～100．98％;线性相关系数分别为0．9996和0．9987。     

多菌灵与乙霉威复配对灰霉病的室内活性研究

采用盆栽喷雾法测试了多菌灵、乙霉威及其9个复配组合对番茄灰霉病多菌灵敏感菌和抗性菌的保护作用,并对2种单剂及其质量比1︰1的复配进行了治疗、淋雨及持效期试验。结果表明:多菌灵与乙霉威的9个配比均表现出相加或增效作用。当多菌灵与乙霉威配比为1︰1时,对敏感菌和抗性菌的共毒系数分别为739.84和460.63,增效作用最显著,且其治疗作用较强,药后10 h淋雨对药效影响小,持效期长达5 d。     

RP-HPLC测定混配制剂中福美双和三唑酮的含量

本文利用反相高效液相色谱外标法测定了混配制剂中福美双和三唑酮的含量，方法的标准偏差分别是0．14和0．10，变异系数分别为0．46％和0．99％，平均回收率分别为99．80％和99．9％。     

乙霉威的气相色谱分析

本文研究了乙霉威的气相色谱分析方法。本方法的变异系数为０．７３％，回收率为９９．０９￣１０１．３６％，该方法具有准确，快速的特点，能够作为乙霉威生产控制分析方法。     

多菌灵、咪鲜胺锰盐复配制剂的液相色谱分析

介绍了杀菌剂多菌灵和咪鲜胺锰盐复配制剂的高效液相色谱分析方法。以甲醇＋水为流动相，使用以Zorbax SB—C18为填料的不锈钢柱和紫外检测器（215nm），对试样中的多菌灵和咪鲜胺锰盐进行反相高效液相色谱分离，外标法定量。方法中多菌灵、咪鲜胺锰盐的标准偏差分别为0．308、0．140，变异系数分别为0．92％、0．85％，回收率分别为99．4％～101．3％、98．9％～101．8％。     

13种杀菌剂对百合枯萎病菌的室内毒力测定

采用生长速率测定法和分生孢子萌发抑制率法测定了13种杀菌剂对百合枯萎病尖孢镰刀菌的毒力作用.结果表明烯唑醇、多菌灵、福美双、己唑醇、苯醚甲环唑、(噁)霉灵对菌丝生长具有明显的抑制作用,其中多菌灵、烯唑醇、(噁)霉灵3种药剂对菌丝生长抑制作用最强.对孢子萌发的抑制作用测定结果表明:多菌灵、(噁)霉灵、福美双、己唑醇、烯唑醇等药剂对百合枯萎病菌孢子萌发具有明显的抑制作用,其中多菌灵、福美双、(噁)霉灵、己唑醇对百合枯萎病菌的分生孢子萌发抑制作用明显强于其他药剂.     

百.乙可湿性粉剂分析方法

采用气相色谱法测定百．乙可湿性粉剂中的百菌清和乙霉威。建立了百菌清和乙霉威的气相色谱测定。     

Aluminum,Arsenic, Beryllium,Cadmium, Chromium,Cobalt, Copper,Iron, Lead,Mercury, Molybdenum,Nickel, Platinum,Thallium, Titanium,Vanadium, and Zinc: Molecular Aspects in Experimental Liver Injury

Experimental liver injury with hepatocelluar necrosis and abnormal liver tests is caused by exposure to heavy metals (HMs) like aluminum, arsenic, beryllium, cadmium, chromium, cobalt, copper, iron, lead, mercury, molybdenum, nickel, platinum, thallium, titanium, vanadium, and zinc. As pollutants, HMs disturb the ecosystem, and as these substances are toxic, they may affect the health of humans and animals. HMs are not biodegradable and may be deposited preferentially in the liver. The use of animal models can help identify molecular and mechanistic steps leading to the injury. HMs commonly initiate hepatocellular overproduction of ROS (reactive oxygen species) due to oxidative stress, resulting in covalent binding of radicals to macromolecular proteins or lipids existing in membranes of subcellular organelles. Liver injury is facilitated by iron via the Fenton reaction, providing ROS, and is triggered if protective antioxidant systems are exhausted. Ferroptosis syn pyroptosis was recently introduced as mechanistic concept in explanations of nickel (Ni) liver injury. NiCl₂ causes increased iron deposition in the liver, upregulation of cyclooxygenase 2 (COX-2) protein and mRNA expression levels, downregulation of glutathione eroxidase 4 (GPX4), ferritin heavy chain 1 (FTH1), nuclear receptor coactivator 4 (NCOA4) protein, and mRNA expression levels. Nickel may cause hepatic injury through mitochondrial damage and ferroptosis, defined as mechanism of iron-dependent cell death, similar to glutamate-induced excitotoxicity but likely distinct from apoptosis, necrosis, and autophagy. Under discussion were additional mechanistic concepts of hepatocellular uptake and biliary excretion of mercury in exposed animals. For instance, the organic anion transporter 3 (Oat3) and the multidrug resistance-associated protein 2 (Mrp2) were involved in the hepatic handling of mercury. Mercury treatment modified the expression of Mrp2 and Oat3 as assessed by immunoblotting, partially explaining its impaired biliary excretion. Concomitantly, a decrease in Oat3 abundance in the hepatocyte plasma membranes was observed that limits the hepatic uptake of mercury ions. Most importantly and shown for the first time in liver injury caused by HMs, titanium changed the diversity of gut microbiota and modified their metabolic functions, leading to increased generation of lipopolysaccharides (LPS). As endotoxins, LPS may trigger and perpetuate the liver injury at the level of gut-liver. In sum, mechanistic and molecular steps of experimental liver injury due to HM administration are complex, with ROS as the key promotional compound. However, additional concepts such as iron used in the Fenton reaction, ferroptosis, modification of transporter systems, and endotoxins derived from diversity of intestinal bacteria at the gut-liver level merit further consideration.     

THERMOPLASTIC,FLEXIBLE, AND RECYCLABLE COMPOSITES,DESIGN, PREPARATION,AND CHARACTERIZATION

Glass fiber reinforced composites based on thermosets are the traditional materials used for many applications due to their good mechanical properties. The non-recyclability of these materials has led to the necessity to develop thermoplastic composites and industrial processes for their manufacture [1]. The present paper deals with the preparation of thermoplastic pre-pregs unidirectionally reinforced with Twarn® and their mechanical characterization.     

DUO-ICP-AES测定精对苯二甲酸中的钴、铬、铁、锰、钼、镍、钛

采用DUO-ICP-AES同时测定精对苯二甲酸中钴、铬、铁、锰、钼、镍、钛,并对仪器的分析线选择、背景校正、入射功率、雾化器压力、辅助气流量、冷却气流量、蠕动泵转速的影响及共存元素的干扰、硝酸铯灰化助剂等因素进行了详细的研究。方法的检测限:钴0.0097 mg/L;铬0.0021 mg/L;铁0.0078 mg/L;锰0.0012 mg/L;钼0.0027 mg/L;镍0.016 mg/L;钛0.0027 mg/L,回收率和精密度分别为93.0%～99.5%和0.37%～3.2%。该方法快速简便,具有良好的精密度和准确度,适用于进出口精对苯二甲酸的日常检验。     

Pd-, Ni-, Fe-, and Co-Catalyzed Cross-Couplings Using Functionalized Zn-, Mg-, Fe-, and In-Organometallics

The development of new methods for preparing polyfunctional organometallics has made a broad range of such reagents available for various transition metal-catalyzed cross-couplings. An overview of the most general preparation methods will be presented. Applications to practical cross-coupling procedures will be covered, emphasizing the functional group compatibility and the reaction scope.     

Sylvatraxx树脂对半钢子午线轮胎胎面胶性能的影响

本文研究了Arizona Chemical公司生产的胎面增强助剂（Tread Enhancement Additive-TEA）Sylvatraxx 4401对半钢子午线轮胎胎面胶性能的影响。结果表明：Sylvatraxx 4401的加入有利于提高白炭黑的分散性,改善混炼胶的加工性能和硫化胶的物理机械性能,能够明显提高胎面的抗湿滑性。随着Sylvatraxx 4401用量的增加,白炭黑在胶料中的分散进一步提高,混炼胶的门尼粘度降低;硫化胶的压缩生热和阿克隆磨耗降低,0oC的tanδ明显提高的同时60oC的tanδ略微降低,有利于胎面胶抗湿滑性能的提高和滚动阻力、动态生热的降低。