Developmental structure of genetic influences on antisocial behavior across childhood and adolescence.

It is necessary to determine if causal influences on developing antisocial behavior change with age to guide both research and theory on its origins. The extent to which the same genetic factors influence antisocial behavior across 4–17 years of age was estimated using 2,482 sibling pairs of varying genetic relatedness. Assessments of antisocial behavior by mothers (4–9 years), mothers and youth (10–13 years), and youth (14–17 years) reflected the changing validity of informants across development. Genetic influences on antisocial behavior at 14–17 years were entirely shared with those on antisocial behavior at 10–13 years according to both informants. Genetic influences on antisocial behavior at 14–17 years were distinct from those at 4–9 years, however. These age differences in genetic influences cannot be fully distinguished from informant differences across age, but the present findings indicate that youth reported to be persistently antisocial during childhood and adolescence are influenced by one set of genetic factors influencing parent-report conduct problems in childhood and a second set of genetic influences on youth-reported delinquency that come into play around the time of the pubertal transition. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sex differences in the genetic and environmental influences on childhood conduct disorder and adult antisocial behavior.

Sex differences in the genetic and environmental influences on childhood conduct disorder and adult antisocial behavior were examined in a large community sample of 6,383 adult male, female, and opposite-sex twins. Retrospective reports of childhood conduct disorder (prior to 18 years of age) were obtained when participants were approximately 30 years old, and lifetime reports of adult antisocial behavior (antisocial behavior after 17 years of age) were obtained 8 years later. Results revealed that either the genetic or the shared environmental factors influencing childhood conduct disorder differed for males and females (i.e., a qualitative sex difference), but by adulthood, these sex-specific influences on antisocial behavior were no longer apparent. Further, genetic and environmental influences accounted for proportionally the same amount of variance in antisocial behavior for males and females in childhood and adulthood (i.e., there were no quantitative sex differences). Additionally, the stability of antisocial behavior from childhood to adulthood was slightly greater for males than females. Though familial factors accounted for more of the stability of antisocial behavior for males than females, genetic factors accounted for the majority of the covariation between childhood conduct disorder and adult antisocial behavior for both sexes. The genetic influences on adult antisocial behavior overlapped completely with the genetic influences on childhood conduct disorder for both males and females. Implications for future twin and molecular genetic studies are discussed. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Genetic and environmental influences on antisocial behavior: A meta-analysis of twin and adoption studies.

A meta-analysis of 51 twin and adoption studies was conducted to estimate the magnitude of genetic and environmental influences on antisocial behavior. The best fitting model included moderate proportions of variance due to additive genetic influences (.32), nonadditive genetic influences (.09), shared environmental influences (.16), and nonshared environmental influences (.43). The magnitude of familial influences (i.e., both genetic and shared environmental influences) was lower in parent-offspring adoption studies than in both twin studies and sibling adoption studies. Operationalization, assessment method, zygosity determination method, and age were significant moderators of the magnitude of genetic and environmental influences on antisocial behavior, but there were no significant differences in the magnitude of genetic and environmental influences for males and females. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Parental discipline and affection and children's prosocial behavior: Genetic and environmental links.

The authors investigated genetic and environmental contributions to the relationships between children's (N = 9,319 twin pairs) prosocial behavior and parental positivity and negativity toward them. Children's prosocial behavior was rated by parents at ages 3, 4, and 7 and by teachers at age 7. At each age, parents described their feelings and discipline toward each twin. Parental positivity was indexed by positive feelings and positive, noncoercive discipline, and parental negativity was indexed by negative feelings and coercive, punitive discipline. Genetics and the environment both contributed to individual differences in prosocial behavior and in parenting. At all ages, parental positivity correlated positively, and parental negativity correlated negatively with prosocial behavior. Genetic factors largely mediated the negative correlation between prosocial behavior and parental negativity. Shared environmental effects contributed mainly to the positive relationship between prosocial behavior and parental positivity. This pattern was found both cross-sectionally and longitudinally. The findings point to the importance of children's characteristics and of the parent-child relationship in family processes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Adolescent personality moderates genetic and environmental influences on relationships with parents.

In contrast with early theories of socialization that emphasized the role of parents in shaping their children's personalities, recent empirical evidence suggests an evocative relationship between adolescent personality traits and the quality of the parent-adolescent relationship. Research using behavior genetic methods suggests that the association between personality and parenting is genetically mediated, such that the genetic effects on adolescent personality traits overlap with the genetic effects on parenting behavior. In the current study, the authors examined whether the etiology of this relationship might change depending on the adolescent's personality. Biometrical moderation models were used to test for gene- environment interaction and correlation between personality traits and measures of conflict, regard, and involvement with parents in a sample of 2,452 adolescents (M age = 17.79 years). They found significant moderation of both positive and negative qualities of the parent-adolescent relationship, such that the genetic and environmental variance in relationship quality varied as functions of the adolescent's levels of personality. These findings support the importance of adolescent personality in the development of the quality of the parent-adolescent relationship. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genetic and environmental influences on personality trait stability and growth during the transition to adulthood: A three-wave longitudinal study.

During the transition to adulthood individuals typically settle into adult roles in love and work. This transition also involves significant changes in personality traits that are generally in the direction of greater maturity and increased stability. Competing hypotheses have been offered to account for these personality changes: The intrinsic maturation hypothesis suggests that change trajectories are endogenous, whereas the life-course hypothesis suggests that these changes occur because of transactions with the social environment. This study investigated the patterns and origins of personality trait changes from ages 17 to 29 using 3 waves of Multidimensional Personality Questionnaire data provided by twins. Results suggest that (a) trait changes were more profound in the first relative to the second half of the transition to adulthood; (b) traits tend to become more stable during the second half of this transition, with all the traits yielding retest correlations between .74 and .78; (c) Negative Affectivity declined over time, and Constraint increased over time; minimal change was observed on agentic or communal aspects of Positive Emotionality; and (d) both genetic and nonshared environmental factors accounted for personality changes. Overall, these genetically informed results support a life-course perspective on personality development during the transition to adulthood. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Testing hypotheses on specific environmental causal effects on behavior.

There have been strong critiques of the notion that environmental influences can have an important effect on psychological functioning. The substance of these criticisms is considered in order to infer the methodological challenges that have to be met. Concepts of cause and of the testing of causal effects are discussed with a particular focus on the need to consider sample selection and the value (and limitations) of longitudinal data. The designs that may be used to test hypotheses on specific environmental risk mechanisms for psychopathology are discussed in relation to a range of adoption strategies, twin designs, various types of "natural experiments," migration designs, the study of secular change, and intervention designs. In each case, consideration is given to the need for samples that "pull-apart" variables that ordinarily go together, specific hypotheses on possible causal processes, and the specification and testing of key assumptions. It is concluded that environmental risk hypotheses can be (and have been) put to the test but that it is usually necessary to use a combination of research strategies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Prosocial development in early adulthood: A longitudinal study.

Consistency of measures of a prosocial personality and prosocial moral judgment over time, and the interrelations among them, were examined. Participants' and friends' reports of prosocial characteristics were obtained at ages 21-22, 23-24, and 25-26 yrs. In addition, participants' prosocial judgment was assessed with interviews and with an objective measure of prosocial moral reasoning at several ages. Reports of prosocial behavior and empathy-related responding in childhood and observations of prosocial behavior in preschool also were obtained. There was interindividual consistency in prosocial dispositions, and prosocial dispositions in adulthood related to empathy/sympathy and prosocial behavior at much younger ages. Interview and objective measures of moral reasoning were substantially interrelated in late adolescence/early adulthood and correlated with participants' and friends' reports of a prosocial disposition. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking.

Although there is a substantial literature on the role of parenting in adolescent substance use, most parenting effects have been small in magnitude and studied outside the context of genetically informative designs, raising debate and controversy about the influence that parents have on their children (D. C. Rowe, 1994). Using a genetically informative twin-family design, the authors studied the role of parental monitoring on adolescent smoking at age 14. Although monitoring had only small main effects, consistent with the literature, there were dramatic moderation effects associated with parental monitoring: At high levels of parental monitoring, environmental influences were predominant in the etiology of adolescent smoking, but at low levels of parental monitoring, genetic influences assumed far greater importance. These analyses demonstrate that the etiology of adolescent smoking varies dramatically as a function of parenting. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Ability factors and environmental influences.

Walter VanDyke Bingham left with his will a memorandum suggesting that there be established, under the auspices of the American Psychological Association, an annual lectureship to call attention to the importance of the discovery and development of talented persons. His wishes have been carried out by Mrs. Walter VanDyke Bingham in her continuing support of the "discovery of the talented" lectures, of which the paper presented here was the twelfth. This twelfth lecture is entitled "Ability Factors and Environmental Influences." (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The developmental origins of a disposition toward empathy: Genetic and environmental contributions.

The authors investigated the development of a disposition toward empathy and its genetic and environmental origins. Young twins' (N = 409 pairs) cognitive (hypothesis testing) and affective (empathic concern) empathy and prosocial behavior in response to simulated pain by mothers and examiners were observed at multiple time points. Children's mean level of empathy and prosociality increased from 14 to 36 months. Positive concurrent and longitudinal correlations indicated that empathy was a relatively stable disposition, generalizing across ages, across its affective and cognitive components, and across mother and examiner. Multivariate genetic analyses showed that genetic effects increased, and that shared environmental effects decreased, with age. Genetic effects contributed to both change and continuity in children's empathy, whereas shared environmental effects contributed to stability and nonshared environmental effects contributed to change. Empathy was associated with prosocial behavior, and this relationship was mainly due to environmental effects. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Heterogeneity among peer-rejected boys across middle childhood: Developmental pathways of social behavior.

The purpose of this longitudinal study was to identify subgroups of rejected boys with different developmental pathways of aggression and prosocial behavior across the elementary school years. Peer, teacher, and parent reports and behavior observations yielded composite scores for aggression and prosocial behavior at 3 measurement waves. A cluster analysis with these composites on 87 initially rejected boys identified 4 subgroups with different developmental pathways of prosocial behavior and aggression that were associated with different patterns of sociometric acceptance and rejection over time and with social emotional adjustment in the last measurement wave. Changes in acceptance and rejection tend to precede changes in aggression and prosocial behavior. Cluster differences on social emotional adjustment indicators converged into 1 moderately discriminating factor, Social Maladaptation in Peer-Oriented Behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genetic and environmental influences on interpersonal cognitions and associations with depressive symptoms in 8-year-old twins.

Less is known about depression in children than in adults. This study integrates fields by combining cognitive and interpersonal research investigating childhood depression symptoms through the use of a genetic framework. Three research questions are addressed. First, what are the associations among interpersonal cognitions, anxiety, and depression? Second, what are the relative magnitudes of genetic and environmental influences on interpersonal cognitions? Third, to what extent do genetic and environmental influences explain associations between interpersonal cognitions and depression? Three hundred pairs of 8-year-old twins reported on symptoms of depression and anxiety by completing the Children's Depression Inventory and the Screen for Childhood Anxiety-Related Emotional Disorders. The authors examined interpersonal cognitions with the Children's Expectation of Social Behaviors and the Perceptions of Peers and Self Questionnaires. Interpersonal cognitions were more strongly correlated with depression (mean r = .35) than with anxiety (mean r = .13). Genetic influence on interpersonal cognitions was small (M = 3%), and associations between interpersonal cognitions and depression were mainly explained by environmental influences. These latter findings may result from interpersonal cognitions in young children, reflecting life experiences as opposed to trait-like cognitive biases. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genetic and environmental influences on academic achievement trajectories during adolescence.

Most studies have considered the effects of particular characteristics on academic achievement individually, which means that little is known about how they function together. Using the population-based Minnesota Twin Family Study, the authors investigated the effects of child academic engagement (interest, involvement, effort), IQ, depression, externalizing behavior, and family environmental risk on academic achievement (reported school grades) from ages 11 through 17. Hierarchical linear growth curve modeling showed main effects on initial reported Grades for all variables, and IQ mitigated the deleterious effects of family risk and externalizing. Only engagement affected change in Grades through adolescence. Influences on initial Grades were strongly genetically influenced, associated primarily with IQ, engagement, and externalizing behavior. Shared environmental influences on initial Grades linked engagement, IQ, and family risk. Genetic influences on change in Grades were substantial, but they were not associated with the academic, family risk, and mental health covarying factors. These results indicate that age 11 achievement and change in achievement through adolescence show systematic patterns and document the existence of individual differences in the commonly shared developmental experience of adapting to the school environment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Personality influences on change in smoking behavior.

Objective: To investigate associations between personality traits in early adulthood (and changes in them) and change in smoking status. Design: Prospective, longitudinal study of a general-population birth cohort. Main Outcome Measures: We measured smoking at ages 18, 26, and 32, and personality at ages 18 and 26 using the Multidimensional Personality Questionnaire (Tellegen & Waller, in press). We assessed personality’s ability to predict future smoking, and assessed how changes in personality traits relate to change in smoking status. Results: Higher aggression and alienation at age 18 predicted smoking at 26; higher self-control and traditionalism at age 18 predicted nonsmoking at 26; and higher alienation at age 26 predicted persistence of smoking to age 32. Personality change between 18 and 26 was associated with change in smoking behavior; those who stopped smoking decreased more than others in negative emotionality and increased more in constraint. Conclusion: These findings suggest that interventions fostering personality change may be effective in reducing smoking and indicate appropriate targets for such antismoking interventions in young people. In particular, high alienation predicted smoking persistence, perhaps due to resistance to existing antismoking messages; we discuss approaches that may overcome this. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cognitive and social influences on early prosocial behavior in two sociocultural contexts.

In this cross-cultural study, we tested 2 main hypotheses: first, that an early self-concept along with self–other differentiation is a universal precursor of prosocial behavior in 19-month-olds, and second, that the importance attached to relational socialization goals (SGs) concerning interpersonal responsiveness (obedience, prosocial behavior) is related to toddlers' prosocial behavior. Contrary to these predictions, the results show that mirror self-recognition, as an indicator of early self-concept, was correlated with toddlers' prosociality only in the Berlin sample (N = 38) and not in the Delhi sample (N = 39). As expected, however, Delhi mothers emphasized relational SGs more strongly than did Berlin mothers. There were no cross-cultural differences in toddlers' prosociality. On an individual level, mothers' emphasis on relational SGs (obedience) was a significant predictor of toddlers' prosocial behavior. On the basis of these results, we propose that situational helping behavior based on shared intentional relations provides an alternative developmental pathway for understanding toddlers' prosocial behavior. This view differs from the often-cited view that anticipating other people as autonomous intentional agents with their own psychological states gives rise to prosocial behavior in toddlers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genetic and environmental influences on girls' and boys' gender-typed and gender-neutral values.

In this first investigation of genetic and environmental influences on children's values, 271 German twin pairs (50.2% boys) reported their values at ages 7–11 years using the Portrait Values Questionnaire (Schwartz & Rubel, 2005). We distinguished between gender-neutral (conservation vs. openness to change) and gender-typed (self-transcendence vs. self-enhancement) values. Boys differed from girls in the importance given to gender-typed benevolence, achievement, and power values. Gender-neutral values showed moderate (.34) and gender-typed values showed higher (.49) heritability, with nonshared environment and error accounting for the remaining variance. For both sexes, substantial genetic effects accounted for the importance children gave to their respective gender-stereotypical end of the self-transcendence versus self-enhancement dimension. However, dramatic sex differences emerged in the gender-atypical end of the distribution. For girls, low self-transcendence (high gender-atypical values) showed a large (.76) group heritability. For boys, gender-atypical values (high self-transcendence) showed no heritability and a modest (.10) shared environment effect. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity: A meta-analysis.

Behavioral genetic investigations have consistently demonstrated large genetic influences for the core symptom dimensions of attention-deficit/hyperactivity disorder (ADHD), namely inattention (INATT) and hyperactivity (HYP). Yet little is known regarding potential similarities and differences in the type of genetic influence (i.e., additive vs. nonadditive) on INATT and HYP. As these symptom dimensions form the basis of the current Diagnostic and Statistical Manual of Mental Disorders subtype classification system, evidence of differential genetic influences would have important implications for research investigating causal mechanisms for ADHD. The current meta-analysis aimed to investigate the nature of etiological influences for INATT and HYP by comparing the type and magnitude of genetic and environmental influences each. A comprehensive literature search yielded 79 twin and adoption studies of INATT and/or HYP. Of these, 13 samples of INATT and 9 samples of HYP were retained for analysis. Results indicated that both dimensions were highly heritable (genetic factors accounted for 71% and 73% of the variance in INATT and HYP, respectively). However, the 2 dimensions were distinct as to the type of genetic influence. Dominant genetic effects were significantly larger for INATT than for HYP, whereas additive genetic effects were larger for HYP than for INATT. Estimates of unique environmental effects were small to moderate and shared environmental effects were negligible for both symptom dimensions. The pattern of results generally persisted across several moderating factors, including gender, age, informant, and measurement method. These findings highlight the need for future studies to disambiguate INATT and HYP when investigating the causal mechanisms, and particularly genetic influences, behind ADHD. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Temperament profiles from infancy to middle childhood: Development and associations with behavior problems.

The authors applied I-States as Objects Analysis (ISOA), a recently proposed person-oriented analytic approach, to the study of temperament development in 921 Norwegian children from a population-based sample. A 5-profile classification based on cluster analysis of standardized mother reports of activity, sociability, emotionality, and shyness at ages 18 months, 30 months, 4-5 years, and 8-9 years was interpretable and highly replicable. The prevalence of temperament profiles changed markedly with age, and individual stability in temperament profiles was significant. Specific typical and atypical developmental sequences of profiles were identified. Selective patterns of concurrent group differences in externalizing and internalizing problems by temperament profiles were remarkably similar across ages. The findings to some degree support the notion that individual temperament-variable values take on meaning in relation to the whole individual configuration and indicate some lawfulness in temperament changes over time. Future person-oriented studies of temperament development should replicate the current results using multiple data sources, rigorous tests of gender differences, and latent group modeling. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Genetic influences on the overlap between low IQ and antisocial behavior in young children.

The well-documented relation between the phenotypes of low IQ and childhood antisocial behavior could be explained by either common genetic influences or environmental influences. These competing explanations were examined through use of the Environmental Risk Longitudinal Twin Study 1994-1995 cohort (Moffitt & the E-Risk Study Team, 2002) of 1,116 twin pairs and their families. Children's IQ was assessed via individual testing at age 5 years. Mothers and teachers reported on children's antisocial behavior at ages 5 and 7 years. Low IQ was related to antisocial behavior at age 5 years and predicted relatively higher antisocial behavior scores at age 7 years when antisocial behavior at age 5 years was controlled. This association was significantly stronger among boys than among girls. Genetic influences common to both phenotypes explained 100% of the low IQ-antisocial behavior relation in boys. Findings suggest that specific candidate genes and neurobiological processes should be tested in relation to both phenotypes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)