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1.
Fischer H?kan; Anderson Jesper L. R.; Furmark Tomas; Wik Gustav; Fredrikson Mats 《Canadian Metallurgical Quarterly》2002,2(3):233
This H/21?O positron emission tomography (PET) study reports on relative regional cerebral blood flow (rCBF) alterations during fear conditioning in humans. In the PET scanner, subjects viewed a TV screen with either visual white noise or snake videotapes displayed alone, then with electric shocks, followed by final presentations of white noise and snakes. Autonomic nervous system responses confirmed fear conditioning only to snakes. To reveal neural activation during acquisition, while equating sensory stimulation, scans during snakes with shocks and white noise alone were contrasted against white noise with shocks and snakes alone. During acquisition, rCBF increased in the right medial frontal gyrus, supporting a role for the prefrontal cortex in fear conditioning to unmasked evolutionary fearrelevant stimuli. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
2.
Hofmann Stefan G.; Moscovitch David A.; Litz Brett T.; Kim Hyo-Jin; Davis Lissa L.; Pizzagalli Diego A. 《Canadian Metallurgical Quarterly》2005,5(4):464
To study the psychophysiological correlates of worrying, the authors recorded heart rate, respiratory sinus arrhythmia (RSA), skin conductance level, and alpha electroencephalographic asymmetry in healthy males during baseline, relaxation, worry induction, and anticipation of an impromptu speech task. Compared with baseline, relaxation, and anticipation, worrying was associated with greater heart rate and lower RSA. Worrying was further characterized by higher skin conductance levels compared with baseline but lower levels than during anticipation. Finally, worrying was associated with relatively greater left frontal activity compared with anticipation. Trait public speaking anxiety was positively correlated with left frontal activity during worrying. These results support the notion that worrying is a unique emotional state that is different from fearful anticipation. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
3.
Reed Laurence J.; Lasserson Daniel; Marsden Paul; Bright Peter; Stanhope Nicola; Kopelman Michael D. 《Canadian Metallurgical Quarterly》2005,19(5):555
Cerebral [1?F]fluorodeoxyglucose positron emission tomography (1?FDG-PET) data from patients suffering amnesia following herpes encephalitis (n = 7) or frontal lobe pathology (n = 14) were compared with data from age-matched nonamnesic subjects (n = 10). All subjects received structural MRI, resting 1?FDG-PET scans, and neuropsychological evaluation. PET data were analyzed using complementary statistical parametric mapping and region-of-interest methods. Differential patterns of hypometabolism were found in patients relative to healthy controls. Factor analysis of the neuropsychological data revealed that memory performance was associated with retrosplenial and medial temporal metabolism, and executive function was associated with dorsolateral frontal metabolism. The association between memory performance and retrosplenial metabolism remained statistically significant after accounting for measures of cerebral atrophy using MRI. The significance of the retrosplenium as a major relay station between the thalamus and the medial temporal and frontal lobes--sensitive to changes in either--is discussed in the light of the findings. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
4.
Schulz Kurt P.; Tang Cheuk Y.; Fan Jin; Marks David J.; Newcorn Jeffrey H.; Cheung Angeles M.; Halperin Jeffrey M. 《Canadian Metallurgical Quarterly》2005,19(3):390
The authors examined inhibitory control processes in 8 adolescents diagnosed with attention-deficit/ hyperactivity disorder (ADHD) during childhood and in 8 adolescent control participants using functional MRI with the Stimulus and Response Conflict Tasks (K. W. Nassauer & J. M. Halperin, 2003). No group differences in performance were evident on measures of interference control and/or response competition created by location and direction stimuli. However, the ADHD group demonstrated significantly greater activation of the left ventrolateral prefrontal cortex during interference control as well as greater activation of the left anterior cingulate cortex, right ventrolateral prefrontal cortex, and left basal ganglia during the dual task of interference control and response competition. The magnitude of the prefrontal and basal ganglia activation was positively correlated with severity of ADHD. Response competition alone did not yield group differences in activation. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献