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食品中丙烯酰胺的研究进展 总被引:1,自引:2,他引:1
丙烯酰胺具有神经毒性,是一种潜在致癌物,广泛分布于热加工食品中,主要通过美拉德反应形成。本文较为全面地介绍了食品中污染物丙烯酰胺的现状、毒性,以及其形成机制、控制途径等方面的研究进展,并对上述研究进展进行了简要的分析和评述。 相似文献
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丙烯酰胺是食品热加工中产生的一种潜在致癌物质,并且具有神经毒性、生殖毒性和遗传毒性,对人体健康危害较大。近年来有关丙烯酰胺的致癌机理、生成机理、分析方法和控制策略等方面都获得诸多研究成果,而对于抑制机理之间的关系,报导较少。本文基于丙烯酰胺的主要形成途径即食品原料中的天冬酰胺和还原糖通过高温加热条件反应生成丙烯酰胺的这一反应为基础,结合最新的文献研究,对丙烯酰胺的抑制作用机理和特定原理下的抑制剂进行系统概述,为将来寻找丙烯酰胺抑制剂和其作用机理研究提供理论参考。 相似文献
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油脂食品中丙烯酰胺问题探讨 总被引:4,自引:0,他引:4
一、丙烯酰胺问题的经纬2002年4月24日,瑞典国家食品局(TheSwedishNationalFoodAdministration:NFA)和斯德哥尔摩大学(StockholmUniversity)的科学家最新公布的研究结果表明,油炸薯条、土豆片等含有淀粉碳水化合物的食物,经120℃以上高温长时间油炸的食品,检测出有致癌可能性的丙烯酰胺(Acrylamide)。一石激起千层浪,该报告一经发表,立即引起了世界各国食品业界的广泛关注。挪威、瑞士、英国、美国等国随即进行了追加试验,并均得到了与瑞典食品局同样的实验结果。由于丙烯酰胺是国际癌症研究机构(IARC)曾于1994年评估认定的一种可致癌… 相似文献
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<正> 4.2 世界各国食品机构分析结果 FAO/WHO专门委员会认定,以瑞典食品局和各国食品机构检测的数据均是可以信赖的。2002年6月,在FAO/WHO专门委员会报告书中,公布瑞典,挪威,瑞士,英国,美国5个国家对各种油脂食品中丙烯酰胺检测结果(表3)。 相似文献
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应用24h膳食回顾询问法估计北京地区居民丙烯酰胺膳食摄入量的研究 总被引:2,自引:0,他引:2
为了解北京地区居民丙烯酰胺的膳食摄入量,应用24h回顾询问法,估计北京地区居民丙烯酰胺摄入量。采用GC-MS方法检测在北京市场上购买的24类(162份)食物,并应用检测结果计算2460份食谱(820人×3d)的丙烯酰胺含量。北京地区居民的丙烯酰胺的每天每人平均摄入量为:男性18.6μg,女性16.6μg;97.5分位数为:男性59.0μg,女性50.4μg。每天每公斤体重摄入量均值:男性0.282μgkgBWd-1,女性0.284μgkgBWd-1;97.5分位数:男性0.898μgkgBWd-1,女性1.007μgkgBWd-1。各餐丙烯酰胺摄入比例为:早餐20.48%,午餐38.99%,晚餐39.42%,零食1.17%。检测结果表明午餐和晚餐食品是北京地区居民丙烯酰胺的主要来源,改变北京地区居民的正餐的烹调方式和控制北京传统早餐食品中的丙烯酰胺含量是减低北京地区居民丙烯酰胺暴露量的主要措施。 相似文献
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The present work describes the development of an optimized matrix solid-phase dispersion (MSPD) procedure for the analysis
of acrylamide in a variety of food matrices, namely, processed cereal products (bread, toasts, breakfast cereals, snacks,
cookies, and biscuits), chocolates, and baby foods. Briefly, 1 g of sample was dispersed with 4 g of C18 solid phase, the whole mixture was further packed in an empty SPE column, and acrylamide was extracted with 6 + 6 ml of water
with a soak step of 5 min each. The aqueous extract was then subject to a bromination procedure and acrylamide quantified
by gas chromatography–mass spectrometry (GC-MS) in SIM mode. Full validation of the method was conducted in samples representatives
of each one of the food groups analyzed including a comparison of the results obtained by using the reported method with those
furnished by a previously developed analytical procedure based on a liquid extraction approach. The MSPD-GC/MS method presented
a limit of detection of 5.2 μg kg−1 and a limit of quantification of 15.7 μg kg−1, and precisions were in the range of 1–7% in all of the food matrices analyzed. Furthermore, the bias of the method was tested
with a certified toasted bread sample. 相似文献
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Acrylamide levels in Finnish foodstuffs analysed with liquid chromatography tandem mass spectrometry
Eerola S Hollebekkers K Hallikainen A Peltonen K 《Molecular nutrition & food research》2007,51(2):239-247
Sample clean-up and HPLC with tandem mass spectrometric detection (LC-MS/MS) was validated for the routine analysis of acrylamide in various foodstuffs. The method used proved to be reliable and the detection limit for routine monitoring was sensitive enough for foods and drinks (38 microg/kg for foods and 5 microg/L for drinks). The RSDs for repeatability and day-to-day variation were below 15% in all food matrices. Two hundred and one samples which included more than 30 different types of food and foods manufactured and prepared in various ways were analysed. The main types of food analysed were potato and cereal-based foods, processed foods (pizza, minced beef meat, meat balls, chicken nuggets, potato-ham casserole and fried bacon) and coffee. Acrylamide was detected at levels, ranging from nondetectable to 1480 microg/kg level in solid food, with crisp bread exhibiting the highest levels. In drinks, the highest value (29 microg/L) was found in regular coffee drinks. 相似文献
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