木糖醇及含木糖醇牙膏的抑菌试验研究

本文通过对木糖醇及含木糖醇牙膏的发酵产酸和抑茵试验，验证了木糖醇及木糖醇牙膏具有抑制致龋茵代谢和杀茵功能，探索了木糖醇的防龋机理。     

木糖醇的生产与发展趋势

介绍了木糖醇的主要功能,分析了传统的木糖醇生产工艺与先进工艺的优劣,并根据国内木糖醇生产现状展望了木糖醇行业未来的发展趋势.     

我国木糖醇生产现状及发展构想

根据相关行业木糖醇应用现状及潜在需求分析，预测了木糖醇行业的发展趋势。并针对我国木糖醇生产企业的生产现状及存在的问题，提出了我国发展木糖醇行业的构想。     

源于发酵液的木糖醇的结晶热力学研究

研究了木糖醇的溶解特性,考察了温度、溶剂组成、杂质等对木糖醇溶解度的影响.结果表明,木糖醇属于溶解度温度系数较大的一类物质;乙醇的加入可降低木糖醇的溶解度;而阿东糖醇、山梨醇等杂质会适当增大木糖醇的溶解度.通过测定木糖醇发酵处理液的介稳区宽度,确定极限过饱和度σ值为0.22,为发酵液制备木糖醇结晶体时的过饱和度确定提供了依据.     

从木糖醇母液中回收结晶木糖醇工艺研究

该工艺针对木糖醇生产中木糖醇母液不易回收木糖醇的问题,重点研究了乙醇重结晶工艺,该工艺简单易行,可以提高木糖醇的收率。     

从木糖酵母液中回收结晶木糖醇工艺研究

该工艺针对木糖醇生产中木糖醇母液不易回收木糖醇的问题，重点研究了乙醇重结晶工艺，该工艺简单易行，可以提高木糖醇的收率。     

我国木糖醇生产现状及发展构想

根据相关行业木糖醇应用现状及潜在需求分析,预测了木糖醇行业的发展趋势。并针对我国木糖醇生产企业的生产现状及存在的问题,提出了我国发展木糖醇行业的构想     

木糖醇发酵模型液的结晶动力学研究

本研究基于发酵法生产木糖醇的特点配制木糖醇发酵模型液,研究了杂质、温度、过饱和度、晶种投入量及晶种规格等因素对木糖醇结晶过程中晶体生长速率的影响。实验表明,木糖醇晶体生长速率与温度及过饱和度成正比关系。山梨醇、阿东糖醇等共存杂质都会阻碍木糖醇的结晶。而晶种投入量及晶种规格对木糖醇晶体生长速率的影响很小,可忽略不计。根据公式及Arrhenius方程,建立木糖醇晶体生长动力学方程,计算晶体生长活化能的大小,并对木糖醇晶体生长限速机制进行了分析。在木糖醇晶体生长的不同阶段,速率控制机制与表面融合机制都起到了控制结晶的作用。     

季也蒙毕赤酵母DQ11发酵酒糟水解液生产木糖醇条件的优化

目的优化季也蒙毕赤酵母DQ11发酵酒糟水解液生产木糖醇的条件。方法通过单因素试验和正交试验,优化季也蒙毕赤酵母DQ11发酵酒糟水解液生产木糖醇的发酵温度、初始pH值、转速和接种量,通过高效液相色谱法测定发酵液中木糖醇的含量;采用最佳发酵条件发酵生产木糖醇,检测木糖醇含量。结果摇瓶发酵酒糟水解液生产木糖醇的最佳条件为:发酵温度28℃,起始pH值5.0,接种量5%(v/v),摇床转速180 r/min;以最佳条件发酵酒糟水解液生产木糖醇的含量为9.016 g/L。结论优化了季也蒙毕赤酵母DQ11发酵酒糟水解液生产木糖醇的条件,为以酒糟生产木糖醇的可能性提供了实验依据。     

FCC级木糖醇中胶体的去除

介绍了在FCC级木糖醇生产中，加入一定量的硅藻土去除木糖醇中胶体的方法，使木糖醇含有胶体的关键质量问题得以解决。     

Chemoenzymatic synthesis: a strategy to obtain xylitol monoesters

BACKGROUND: Fatty acid sugar esters are used as non‐ionic surfactants in cosmetics, foodstuffs and pharmaceuticals. In particular, monoesters of xylitol have attracted industrial interest due to their outstanding biological activities. In this work, xylitol monoesters were obtained by chemoenzymatic synthesis, in which, first, xylitol was made soluble in organic solvent by chemo‐protecting reaction, followed by enzymatic esterification reaction using different acyl donors. A commercial immobilized Candida antartica lipase was used as catalyst, and reactions with pure xylitol were carried out to generate data for comparison. RESULTS: t‐BuOH was found to be the most suitable solvent to carry out esterification reactions with both pure and protected xylitol. The highest yields were obtained for reactions carried out with pure xylitol, but in this case by‐products, such as di‐ and tri‐esters isomers were formed, which required a multi‐step purification process. For the systems with protected xylitol, conversions of 86%, 58% and 24% were achieved using oleic, lauric and butyric acids, respectively. The structures of the monoesters were confirmed by ¹³C‐ and ¹H‐NMR and microanalysis. CONCLUSION: The chemoenzymatic synthesis of xylitol monoesters avoided laborious downstream processing when compared with reactions performed with pure xylitol. Monoesters production from protected xylitol was shown to be a practical, economical, and clean route for this process, allowing a simple separation, because there are no other products formed besides xylitol monoesters and residual xylitol. Copyright © 2009 Society of Chemical Industry     

Purification and crystallization of xylitol from fermentation broth of corncob hydrolysates

Xylitol, a five-carbon sugar alcohol, is a valuable sugar substitute, and widely used in the pharmaceutical, odontological and food industry due to its interesting properties. In the past decades, the xylitol industry has grown rapidly and more attention has been focused on xylitol purification, which possesses an important proportion of the whole industry. In our paper, the purification and crystallization of xylitol fermentation broth by biotechnology using corncob hydrolysates as substance were studied. An initial xylitol fermentation broth was decolored with activated carbon (1% M⁻¹, 60°C, 165 rpm), desalted with a combination of two ionexchange resins (732 and D301), and residual sugars were separated with UBK-555(Ca²⁺). Then the solution was vacuum-concentrated up to supersaturation (750 g/L xylitol). After adding 1% xylitol crystal seeds, the supersaturated solution was cooled to −20°C for 48 h. The crystalline xylitol of a regular tetrahedral shape with purity 95% and crystallization yield 60.2% was obtained from the clarified xylitol fermentation broth. An intact, economical and environmental-friendly route of purification and crystallization of xylitol from fermentation of corncob hydrolysates was obtained, and its experimental procedure and data provided a sound basis for large-scale industrial production.     

Purification and crystallization of xylitol from fermentation broth of corncob hydrolysates

Xylitol, a five-carbon sugar alcohol, is a valuable sugar substitute, and widely used in the pharmaceutical, odontological and food industry due to its interesting properties. In the past decades, the xylitol industry has grown rapidly and more attention has been focused on xylitol purification, which possesses an important proportion of the whole industry. In our paper, the purification and crystallization of xylitol fermentation broth by biotechnology using corncob hydrolysates as substance were studied. An initial xylitol fermentation broth was decolored with activated carbon (1% M-1, 60°C, 165rpm), desalted with a combination of two ion-exchange resins (732 and D301), and residual sugars were separated with UBK-555(Ca²⁺). Then the solution was vacuum-concentrated up to supersaturation (750g/L xylitol). After adding 1% xylitol crystal seeds, the supersaturated solution was cooled to −20°C for 48h. The crystalline xylitol of a regular tetrahedral shape with purity 95% and crystallization yield 60.2% was obtained from the clarified xylitol fermentation broth. An intact, economical and environmental-friendly route of purification and crystallization of xylitol from fermentation of corncob hydrolysates was obtained, and its experimental procedure and data provided a sound basis for large-scale industrial production.     

木糖醇牙膏的配方与制造

对木糖醇牙膏的功能、配方、制备使用方法进行了讨论。给出了一种木糖醇牙膏的配方。     

熔融共晶体木糖醇的合成及应用

研究了一种新型甜味剂——熔融共晶体木糖醇的合成及应用,考察了加入晶种的温度、晶种的量以及降温速度、搅拌速度对共晶体形成的影响,并验证了所得熔融共晶体木糖醇产品的性能。     

麦草酸水解及水解液木糖发酵的研究

采用甲酸/盐酸水解体系水解麦草,发现 65℃ 水解 0.5 h 可实现麦草中半纤维素的充分水解。选用热带假丝酵母发酵麦草甲酸水解液制取木糖醇。分别研究了在不同浓度甲酸及甲酸根条件下D-木糖的发酵效果,发现在 2 g/L 的甲酸及 5 g/L 的甲酸根条件下,D-木糖实现发酵并得到最大产率的木糖醇,高浓度的甲酸及甲酸根都会抑制D-木糖的发酵。采用D311型阴离子交换树脂脱除甲酸根,实现了麦草水解液的发酵,木糖醇最高得率为 16.88%(木糖醇/木糖)。     

Measurement and correlation of solubility of xylitol in binary water+ethanol solvent mixtures between 278.00 K and 323.00K

The solubility of xylitol in ethanol+water solvent mixtures was measured at temperatures ranging from 278.00 K to 323.00 K at atmospheric pressure by using a laser technique. The results of these measurements were correlated by the combined nearly ideal binary solvent CNIBS/Redlich-Kister equation. The experimental solubility and correlation equation in this work can be used as essential data and models in the purification process of xylitol. The variant 2 in the CNIBS/R-K models was confirmed to be more adaptable to predict solubility of xylitol in binary ethanol +water system. Using the experimentally measured solubilities, the thermodynamic properties of dissolution of xylitol, such as Gibbs energy, molar enthalpy of dissolution, and molar entropy of dissolution, were calculated.