Reducing craving for cigarettes while decreasing smoke intake using capsaicin-enhanced low tar cigarettes.

The effects on smoking behavior and subjective evaluation of adding capsaicin (a pungent principle of chili pepper) to a low tar and nicotine cigarette were studied in 12 cigarette smokers. In a 4-hr session, Ss inhaled smoke from 3 types of cigarettes: low tar and nicotine with capsaicin added; low tar and nicotine without capsaicin (control); and commercial high tar and nicotine. Ss puffed significantly less on the capsaicin cigarettes than on the other 2 types of cigarettes and reported greater reduction in cigarette craving after smoking capsaicin cigarettes than after smoking control low nicotine cigarettes. Estimated nicotine intake and respiratory tract sensations for the capsaicin cigarettes were also significantly higher than for the control cigarettes. Results support the view that respiratory tract sensations are important in reducing smokers' craving for cigarettes and in modulating smoking behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Does switching to low tar/nicotine/carbon-monoxide-yield cigarettes decrease alveolar carbon monoxide measures? A randomized controlled trial.

Assessed the effects of changing to low tar/nicotine/carbon-monoxide-(CO)-yield cigarettes on alveolar carbon monoxide over a 5–6 wk period for 40 adult chronic smokers of high tar/nicotine/CO cigarettes. Ss were assigned to either a 5-wk step-wise brand-reduction treatment or to a delayed-treatment control group. Ss were assessed for (a) resting CO body burden and CO uptake per cigarette and (b) smoking topography and rate. Although CO uptake was significantly lower after Ss smoked low tar/nicotine/CO cigarettes than after smoking their original brand, resting CO body burden did not change. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Does cigarette smoking cause stress?

Smokers often report that cigarettes help relieve feelings of stress. However, the stress levels of adult smokers are slightly higher than those of nonsmokers, adolescent smokers report increasing levels of stress as they develop regular patterns of smoking, and smoking cessation leads to reduced stress. Far from acting as an aid for mood control, nicotine dependency seems to exacerbate stress. This is confirmed in the daily mood patterns described by smokers, with normal moods during smoking and worsening moods between cigarettes. Thus, the apparent relaxant effect of smoking only reflects the reversal of the tension and irritability that develop during nicotine depletion. Dependent smokers need nicotine to remain feeling normal. The message that tobacco use does not alleviate stress but actually increases it needs to be far more widely known. It could help those adult smokers who wish to quit and might prevent some schoolchildren from starting. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Automatic affective responses to smoking cues.

The authors examined automatic emotional reactions to smoking cues among 35 smokers and 25 nonsmokers (32 women and 28 men), using a novel implicit measure, the Affect Misattribution Procedure. Associative-learning theories of addiction suggest that smokers develop positive responses to cues linked to the rewarding effects of nicotine. Prior research, however, has yielded mixed evidence for whether smokers have favorable or unfavorable automatic responses to smoking cues. These findings may depend on the methods used to measure implicit responses. Using the Affect Misattribution Procedure, the authors found that nonsmokers responded to smoking cues with clear negative affect, whereas smokers' responses depended on individual differences in current smoking withdrawal. Smokers having withdrawal symptoms and those most motivated to smoke showed favorable emotional responses to smoking cues, but those with no withdrawal or low motivation to smoke showed negative responses. These results help integrate previous studies finding that smokers have negative automatic responses to cigarettes with those studies finding that smokers' responses were relatively positive. The results are important for theories that emphasize the role of cue conditioning in maintaining addiction because these theories assume, consistent with the current findings, that smoking cues can take on positive reward value. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Smoking behavior and smoking history of tobacco chippers.

Nicotine produces dependence in almost all cigarette smokers. 65 chippers (anomalous smokers who smoke regularly but at very low levels [1–5 cigarettes/day]) were compared with 72 matched regular smokers (20–40 cigarettes/day). Despite having smoked an average of 46,000 cigarettes in 19 yrs of smoking, chippers demonstrated little sign of nicotine dependence. They reported frequent casual abstinence from smoking without withdrawal symptoms, smoked their 1st cigarette of the day hours after waking, and scored low on a modified Fagerstrom Tolerance Questionnaire, a measure of tobacco dependence. Although most chippers had never smoked heavily, a small subgroup of chippers reported previous extended periods of heavy smoking, which suggests that some people may be able to overcome dependence while continuing to smoke. These "converted chippers" could not be distinguished from "native chippers" on the basis of their current smoking behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Analysis of nicotine and cotinine in the hair of hospitality workers exposed to environmental tobacco smoke

The purpose of this study was to determine if hair nicotine and cotinine levels reflect relative exposure to environmental tobacco smoke (ETS) in subjects who worked in the hospitality industry, where public smoking was permitted. Hair samples from 26 subjects were analyzed by gas chromatograph/mass spectrometry techniques for nicotine and cotinine. An exposure gradient was shown for nicotine but not cotinine. Among nonsmokers, those working in bars where there are no public smoking restrictions had the highest hair nicotine levels, which were close to levels found in smokers. Nicotine measured in hair is useful as a biological marker for exposure to ETS from multiple sources. Bar workers in particular are exposed to high levels of ETS, which may adversely affect the health of nonsmokers.     

Measures of affect and nicotine dependence predict differential response to smoking cessation treatments.

126 smokers were randomly assigned to 6-session smoking cessation treatments consisting of 1 of 2 counseling strategies (skills training or support) and 1 of 2 nicotine exposure strategies (nicotine gum or rapid smoking). Counseling and nicotine strategies were completely crossed: All 4 combinations resulted in equivalent 1-yr abstinence rates. Skills training produced higher initial cessation and more coping responses posttreatment than did support. Rapid smoking, but not nicotine gum, produced tachycardia to the taste of cigarettes posttreatment, consistent with cigarette aversion. The treatments were differentially effective among subpopulations of smokers: Ss high in pretreatment negative affect responded best to support counseling; those low in pretreatment negative affect responded best to skills training. Self-reports of pretreatment craving predicted response to the nicotine-exposure treatments. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Olfactory thresholds for nicotine and menthol in smokers (abstinent and nonabstinent) and nonsmokers

Nonsmokers and smokers were compared for olfactory sensitivity to two odors associated with cigarettes: nicotine and menthol. Smokers were tested twice--while nonabstinent, and after 16-20 h of smoking abstinence. Smokers showed a higher olfactory threshold for nicotine than did nonsmokers, but the same threshold for menthol. Furthermore, when the smokers were abstinent, they showed a lower olfactory threshold for nicotine than when they were nonabstinent, but again, the same threshold for menthol. These results suggest a nicotine specific olfactory deficit in smokers that is reduced during abstinence.     

In smoke's way: Socioemotional reactions to another's smoking.

Assessed the immediate impact of second-hand cigarette smoke on interpersonal attraction and personal feelings. 75 US Army and Air Force enlisted men who were either nonsmokers or smokers and who either refrained or indulged during the session interacted with a stranger who either did not smoke, smoked courteously, or smoked discourteously. Following the encounter, Ss rated the other person on several evaluative dimensions and also rated their own affective state. Nonsmoking Ss made more favorable evaluations and reported a more pleasant affective experience after interacting with a nonsmoking stranger as compared to either a courteous or a discourteous smoker. Smoking Ss who refrained made their most positive ratings in the presence of a courteous smoking other and their most negative ratings in the company of a discourteous one. In contrast to both nonsmokers and smokers who refrained, smokers who indulged during the session made the most favorable ratings when exposed to an indiscriminant smoking stranger. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Behavioral and physiological effects of low-nicotine cigarettes during rapid smoking.

Compared the effects of rapid smoking using medium-tar/nicotine or low-tar/nicotine cigarettes on physiological and behavioral responses in a randomized, double-blind clinical trial with 24 Ss. Results show equivalent heart rate, blood pressure, and carbon monoxide levels after rapid smoking either low- or medium-yield cigarettes. Behavioral topography measures differed significantly when low-nicotine cigarettes were smoked. Also, Ss who did remain abstinent at subsequent follow-up showed less change in rated aversiveness during rapid smoking than Ss who did not remain abstinent. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Daily Processes in Stress and Smoking: Effects of Negative Events, Nicotine Dependence, and Gender.

The author used a multilevel daily process design to examine relations among daily negative events, perceived stress, smoking, and smoking urges. The moderating effects of gender and nicotine dependence were also explored. Fifty-one adult community-residing smokers recorded negative events, perceived stress, cigarette smoking, and urges to smoke 4 times daily for 14 days. Analyses of within-person relations showed that participants smoked more cigarettes and experienced more urges to smoke on occasions with higher numbers of negative events and higher levels of perceived stress. These relations were stronger for men than for women. Nicotine dependence did not interact with events or stress in predicting smoking or urges. These findings build on laboratory studies and cross-sectional surveys by showing that in naturalistic settings, occasions with negative events and perceived stress are associated with smoking and urges to smoke. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Blood nicotine and carboxyhemoglobin levels after rapid-smoking aversion therapy.

Studied blood nicotine and carboxyhemoglobin (COHb) levels after rapid smoking in 5 male and 10 female smokers. Male Ss were under 40 yrs of age and females were under 50. Blood nicotine averaged 48.1 ng/mg after rapid smoking compared to 32.4 ng/ml after normal smoking, and COHb levels averaged 12.1% and 8.9%, respectively. Both differences were significant. Normal smoking levels of 92 smokers in other studies averaged around 30 ng/ml nicotine and 8.2–8.5% COHb. There was no evidence that the degree of nicotine and carbon monoxide intoxication produced during raid smoking had any relation to the reduction in the desire to smoke immediately after the session or the decrese in cigarette consumption on the following day. The potential risks of rapid smoking are discussed. It is suggested that these risks might be reduced by using a beta-adrenergic blocker and that the procedure could be made completely safe, possibly without loss of treatment effect, if Ss were instructed not to inhale. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cigarette mentholation increases smokers' exhaled carbon monoxide levels.

12 male smokers participated in 3 controlled-dose smoking sessions spaced 1 wk apart. In each session, Ss inhaled 1,200 cc of cigarette smoke. Menthol dosage varied across sessions, such that Ss smoked experimental cigarettes that had been injected with 0, 4, or 8 mg of menthol. Exhaled CO levels increased concomitantly with menthol dosage. There were no differences in smoking topography across the 3 conditions. The ability of menthol to increase the toxicity of cigarette smoke by raising CO levels is discussed. Results suggest that menthol cigarette preference may account for some of the racial differences in smoking behavior and smoking-related outcomes found in past literature. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Smoking at home: The impact of smoking cessation on nonsmokers' exposure to environmental tobacco smoke.

Nonsmokers who live with smokers are at increased risk for chronic disease. This study evaluated the impact of eliminating smoking in the home on nonsmokers' environmental tobacco smoke (ETS) exposure. Nonsmokers participated in measurements of their ETS exposure before and after the smoker in their home quit smoking. A matched comparison group of nonsmokers from nonsmoking homes was also included. ETS exposure was assessed using passive nicotine monitors, an exposure diary, and a questionnaire. Nonsmokers from smoking homes had significantly higher exposure to ETS than those from nonsmoking homes. There was a 60% reduction in nicotine levels following smoking cessation by the household smoker. However, there were still detectable levels of nicotine measured at posttest. These results have important implications for individual risk reduction and public health policy. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Fear reactivity to bodily sensations among heavy smokers and nonsmokers.

Individuals who smoke are more likely to experience panic attacks and develop panic disorder than those in the general population. One possible explanation is that smokers may experience a heightened fear response to somatic disturbances. To date, few laboratory studies have tested this hypothesis directly. The present study examined 24 adult heavy smokers (10 females) in 12-hr nicotine withdrawal and 24 adult nonsmokers (12 females) on subjective and physiological reactivity to a 4-min carbon dioxide rebreathing challenge. Results indicate that, despite an attenuated acceleration in respiration during the challenge, smokers experienced a significantly greater increase in self-reported panic symptoms than nonsmokers. In addition, smokers reported significantly greater trait levels of suffocation fear prior to the challenge. Findings are discussed with respect to the role of smoking in panic vulnerability. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Distribution of major and minor alkaloids in tobacco, mainstream and sidestream smoke of popular Indian smoking products

Various Indian smoking products--cigarette, bidi, chutta and a brand of US cigarette--were analysed by gas chromatography-flame ionization detection (GC-FID) for the levels of nicotine and minor tobacco alkaloids in tobacco, mainstream smoke (MS) and sidestream smoke (SS) employing modified smoking standards, namely two puffs/min. The analysis clearly demonstrated relatively higher levels of nicotine and minor tobacco alkaloids in tobacco from bidi (37.7 mg/g) and chutta (34.5 mg/g) when compared with Indian and US cigarettes (14-16 mg/g) studied. Relatively lower levels (SS/MS) of nicotine in SS from bidi and chutta compared with Indian/US cigarettes, suggest that the contribution of nicotine in SS from a single bidi/chutta to environmental tobacco smoke (ETS) is very much less than that of a single Indian/US cigarette. Reduced levels of nicotine in SS of bidi/chutta result in relatively higher deliveries of nicotine in MS as reflected by higher MS/SS values. The observed differences are likely to be due to difference in tobacco processing, burning rate/temperature and design of the smoking product.     

Chewing gum affects smoking topography.

In a previous study, Wrigley's chewing gum was shown to reduce cravings to smoke and nicotine withdrawal when smokers were not allowed access to cigarettes. The present study expanded these findings by examining smoking behavior of 20 dependent cigarette smokers who were allowed free access to cigarettes throughout the study session but were encouraged and rewarded not to smoke. Each experimental session consisted of the participant watching a movie, then waiting an additional 30 min. Half of the participants were assigned to a gum condition in which they were asked to chew at least one piece of gum and had free access to chewing gum throughout the experimental session; half were assigned to a no-gum control. Results from this study indicate that when gum was present, participants took significantly fewer puffs and abstained for a longer period of time until their first cigarette. These results suggest that chewing gum may facilitate quit attempts. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Electroencephalographic responses to photic stimulation in habitual smokers and nonsmokers.

Performed 2 studies in which EEGs of 45 habitual cigarette smokers and of 59 nonsmokers were taken before and after they were required to smoke a cigarette. The EEGs were scored for incidence of EEG "driving" responses to photic stimulation, an index that appears to reflect the balance between central adrenergic and cholinergic nervous systems. Findings suggest that smokers tend to have a central autonomic balance less in favor of adrenergic functioning than do nonsmokers. Cigarette smoking may alleviate a possible central adrenergic insufficiency of smokers. These findings suggest a solution to "Nesbitt's paradox," which has reference to the fact that while nicotine is a central adrenergic stimulant, smokers describe the effect of smoking in sedational terms (i.e., as relaxing or calming). (22 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Self-monitoring and reactivity in the modification of cigarette smoking.

The reactive effects of self-monitoring (SM) as a function of varying the specific nature of the target behavior and the perceived negative consequences of the behavior were investigated with 40 20–55 yr old chronic smokers (at least 15 cigarettes/day for 2 yrs). Ss were assigned to 1 of 4 conditions from stratified blocks based on initial smoking rates: (a) SM nicotine plus health hazard information; (b) SM nicotine with no health hazard information; (c) SM cigarettes plus health information; and (d) SM cigarettes with no health information. Ss self-monitored during a 4-wk nondemand phase and during a 4-wk treatment phase or until they quit smoking. The 2 nicotine SM groups showed greater reactivity. There were no differences among groups as a function of exposure to health hazard information. Results are discussed in relation to models of self-control and previous investigations of other parameters of reactive SM. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evidence that suggests a negative association between cigarette smoking and learning performance

The results of this study indicate that tobacco smoking may have a deleterious effect on the learning process. One hundred and fifteen male volunteers were assessed on four learning tasks. Those Ss who smoked in excess of 12 cigarettes per day did significantly less well, as a group, than nonsmokers and light smokers on three of the four learning tests.