臭氧治疗宫颈HPV感染的疗效观察

目的 探讨臭氧治疗宫颈人乳头状瘤病毒(HPV)感染的疗效.方法 将80例宫颈HPV阳性患者随机分为实验组和对照组,每组各40例,实验组采用臭氧水阴道冲洗,对照组采用0.1%新洁尔灭阴道冲洗,分别于三个疗程后检测宫颈HPV,比较2组的转阴率.结果 臭氧水阴道冲洗治疗转阴率优于0.1%新洁尔灭阴道冲洗(P＜0.01),差别具有统计学意义.结论 臭氧治疗宫颈HPV感染有一定疗效,可避免宫颈癌的发生.     

阴道镜诊断宫颈病变52例分析

目的:探讨阴道镜对宫颈病变的诊断价值.方法:将我院2009年6月至2010年6月因宫颈病变就诊的52例,该组患者均采用阴道镜检查及宫颈活检,分析阴道镜检查及活检结果,评定该检测方法的临床价值.结果:该组患者中以慢性宫颈炎最多,占76.9%(40/52).阴道镜检查阴性病例44例,组织病理学检查阴性病例43例,诊断符合率为97.7%(43/44).且两者的阳性诊断符合率为88.9% (8/9).结论:阴道镜检查技术方法简单方便,且准确率较高,有较好的临床应用价值.     

宫颈液基细胞学检查临床病理分析

目的:探讨宫颈液基细胞学与组织病理学诊断的符合情况,评估液基细胞学技术及TBS诊断系统在妇科普查宫颈疾病中的价值.方法:对6012例患者做Thin Prep膜式薄层液基细胞学检查,结果异常者依次做5%醋酸宫颈染色,肉眼观察并阴道镜检查及宫颈多点活检病理组织学检查.细胞学诊断采用TBS(2001)分级报告系统,阳性诊断包括意义不明的不典型鳞状细胞(ASC-US)及以上标本;且所有ASC-US以上病变的患者全部有病理组织学诊断结果,并对两者进行了对照分析.结果:6012份宫颈细胞学检查与组织病理学对照结果显示:2例鳞状细胞癌(SCC)均符合,高级别鳞状上皮内病变(HSIL)76.87%,低级别鳞状上皮内病变(LSIL)为78.65%.结论:应用液基细胞学制片方法、准确掌握TBS的诊断标准可确保宫颈细胞学检查的准确性,并可及早发现宫颈早期病变.     

影响新生儿疾病筛查的原因及对策

目的 提高新生儿疾病筛查率,减少残疾儿的发生,提高人口素质.方法 将2005年1月～2008年12月在本院出生新生儿702人作为问题组,2009年1月～2010年12月出生新生儿1540人作为对策组,将问题组新生儿疾病筛查情况进行统计分析,根据存在的问题提出相应的对策,并在对策组实施.结果 问题组新生儿疾病筛查率为25.78%,对策组新生儿疾病筛查率为95.26%.结论 通过提高认识,大力宣传,实施系统全面的培训和指导,化验结果 追踪随访等对策后,大大提高了新生儿疾病筛查率.     

预防老年人常见慢性疾病的社区护理

目的:探讨预防老年人常见慢性疾病的社区护理的有效措施及效果.方法:选取我社区内老年人460例老年人为研究对象,在2008年6月至2009年6月期间对其实施高血压、糖尿病、冠心病等常见慢性疾病的预防性护理,主要措施有心理干预及健康教育、饮食指导、自我检测、建立档案定时随访以及运动指导等,将该组老年人慢性疾病的阳性检出率与未实施预防护理前的阳性检出率做比较.结果:检出的疾病多是高血脂、高血压、血糖升高、脂肪肝等慢性疾病,预防护理实施后的疾病检出率为38.9%(179/460)显著低于实施前60.0%(276/460),P<0.05.结论:预防性社区护理措施可以降低老年人常见慢性疾病的发病率.     

呼吸训练对呼吸系统疾病康复的影响分析

目的:探讨呼吸系统疾病康复中呼吸训练的影响.方法:选择我院2010年1月至2011年1月收治的呼吸系统疾病患者120例,对其实施呼吸训练进行康复治疗,回顾分析其临床效果.结果:本组120例患者中,117例治愈或好转,占97.5%,另外3例患者因并发其它疾病或高龄而导致呼吸循环衰竭.结论:呼吸训练在呼吸系统疾病的康复中具有十分重要的临床意义,具备简单方便、无痛无创的特点,不需医疗费用,实用价值较高,有效的预防和控制了疾病的发生,提高了生命质量.     

输血前血液传染指标检测的意义

目的:了解患者输血前5项血液传染指标,分析输血传染原因,避免和预防医院感染和医疗纠纷的发生.方法:对2276例输血前患者血液进行ALT、HBsAg、抗HCV、抗HIV.结果:2276例输血患者ALT异常(>40U)296例(12.59%),HBsAg阳性为195例(8.57%),抗HCV阳性6例(0.26%),梅毒抗体阳性1例(0.044%),抗HIV未检出.结论:输血前患者5项血液传染指标阳性率明显高于同期健康体检者,因此,对输血前患者进行血液传染指标的检测,对减少和杜绝经血液传播疾病而引起的医患纠纷,保护医患双方利益都有重要意义.     

局部植入缓释氟尿嘧啶配合热放疗治疗宫颈癌临床初步研究

目的:探讨局部植入缓释氟尿嘧啶配合射频深部热疗加常规放疗宫颈癌的临床疗效.方法:宫颈肿瘤局部植入缓释氟尿嘧啶配合射频深部热疗加常规放疗30例Ⅱb期-Ⅲb期宫颈癌(联合组),同期进行射频深部热疗加常规放疗35例作为对照组,比较2组的近期疗效和毒副作用.联合组采用15MV-X线盆腔外照射50Gy/25次/5周(其中全盆25-30Gy),192Ir后装腔内放疗A点剂量30-35Gy(5Gy/次,6-7次,2次/周).放疗期间配合射频深部热疗8-10次,2次/周;并在放疗期间直视下宫颈肿物植入缓释氟尿嘧啶200-600mg.对照组盆腔外照射、射频深部热疗和腔内后装治疗剂量同联合组.结果:联合组和对照组的肿瘤完全缓解率分别为93.3%(28/30)和74.3%(26/35)(X2＝4.169,P＝0.041).有52例随访满3年,3年局控率分别为92%和70.4%(X2＝4.001,P＝0.045),3年总生存率分别为84%和70.4%(X2＝1.387,P＝0.239).两组直肠和膀胱近期反应、骨髓抑制无明显差异.结论:局部植入缓释氟尿嘧啶热化放疗可以提高宫颈癌的缓解率、局控率和生存率,不明显增加毒副作用.     

654-2针在产程中的应用观察

2007年1月1日～2008年1月1日我们对 100例宫颈Bishop评分中宫颈消评0分、宫颈硬度评0分、宫口开大0cm、先露位置-3(宫颈位置后、中、前未分)的初产妇(参见宫颈Bishop评分法)进入分娩期静脉推注5%GS20ml+654-2针10㎎以催宫颈短期成熟,提高宫颈Bishop评分、加速产程进展、降低剖宫产率,效果满意,现报道如下.     

应用LSI9q34探针及ES/DCDF探针检测慢性粒细胞白血病患者der(9)缺失的研究

目的 研究慢性粒细胞性白血病(CML)患者衍生9号染色体[der(9)]部分序列缺失情况,探讨LSI 9q34探针在检测der(9)缺失中的联合应用价值.方法 对52例CML患者采用不加任何刺激剂的骨髓进行24 h短期培养法制备染色体,吉姆萨显带进行核型分析.应用ES/DCDF探针及LSI 9q34探针对骨髓间期细胞进行荧光原位杂交,并检测der(9)部分序列缺失.结果 52例中经ES/DCDF探针检测全部为ber-abl融合基因阳性,其中12例患者伴有der(9)部分缺失,占23.0%,经LSI 9q34探针检测有11例患者伴有der(9)部分缺失.结论 LSI9q34探针在判断CML患者是否伴有der(9)缺失方面有较好的特异性.伴有缺失的患者疾病进展较快,预后较差,甲磺酸依马替尼治疗不能完全逆转其负性作用,建议所有bcr-abl融合基因阳性的CML患者均应行 LSI 9q34探针检测,以指导临床治疗.     

转炉炉壳热应力分析

根据实际转炉建立实体模型。以有限元为手段,考虑了炉衬和炉壳材料的物性参数随温度变化的特点和炉衬与炉壳之间膨胀间隙,计算了转炉炉壳在温度载荷和炉衬膨胀压力同时作用下的热应力。所得结果可为转炉炉壳设计提供依据。     

焦炭热性能指标意义浅析

通过对焦炭在高炉内的历程及其变化规律的剖析,阐述焦炭热性能指标的意义,形象地把焦炭在高炉内的损耗分为三部分(M1,M2,M3)。指出M2对焦比及焦炭价格有一定的指导作用。     

Results of treatment of cancer of the cardia

Cancer of the cardia is traditionally discussed with cardiac cancer of the lower portion of the esophagus and upper gastric cancer invading the esophagus, and the specific characteristics of cancer of the cardia have never been clearly defined. We reviewed the outcome of 172 patients with adenocarcinoma of the cardia who had undergone radical surgery between 1949 and 1994 in the Division of Gastrointestinal Surgery of the Cancer Institute Hospital. The centers of the tumors were located within 2 cm above and below the boundary between the esophagus and the stomach, and their longitudinal diameter was less than 8 cm. We divided the patients into an early period (1949-1979; n = 79) and a late period (1980-1994; n = 93), and focused on the historical transition. There were no differences in patient gender or histology between the two periods. However, the late period was associated with fewer cases of esophageal invasion and shorter longitudinal diameter, as the age of the population advanced. The number of advanced cancers such as the localized and infiltrative type had decreased, and early cancer and early clinical stage had become more common, but despite the fact that the number of early cancers had increased, extended dissection, such as thoracic and paraaortic lymph node dissection, was performed more frequently. By clinical stage, the long-term outcome markedly improved in Stage I patient in the late period, and tended to improve in Stage II and III patients. This appears to have been attributable to the prevention of micrometastasis by extended dissection, although the number of early cancers is another major potential cause. There were no differences in the outcome of Stage IV patients between the two periods, and further advances in multimodality therapy must be awaited. The range of resection is basically proximal gastrectomy, and if there are adequate indications, the prognosis is favorable. In view of the status of lymphatic flow and lymph node metastasis, and long-term results, lateroaortic lymph node dissection is important. Since the number of early cancer patients has been increasing, if intraabdominal recurrence is prevented, intrathoracic lymph node dissection will contribute greatly to the outcome of such patients.     

The effect of amount of possession of the trait of hostility on accuracy of perception of hostility in others.

Some theories of personality hold that an individual's perception of others is influenced by his own personality characteristics; more specifically, that a trait of low social value will be projected more into others, and that insight into the possession of these characteristics reduces this distortion. These 2 hypotheses were tested by having a group of college students rate each other (including themselves) on degree of friendliness or hostility. Agreement with group rating about self yielded the insight score. In general, the hypotheses were supported; the "friendly" Ss were most accurate in their perception of others, and insight was positively associated with accurate perception. From Psyc Abstracts 36:04:4HL16M. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Comparison of rates of infection of two methods of emergency ventricular drainage

The rates of infection of two methods of external ventricular drainage in use at Atkinson Morley's Hospital--namely, (a) percutaneous drainage with Rickham reservoirs and (b) tunnelled ventriculostomies--were compared in this retrospective review. Percutaneous drainage of CSF with Rickham reservoirs was associated with a 27% rate of infection as identified by positive microbiological cultures; tunnelled ventriculostomy catheters had a 10% infection rate. The difference in the infection rate between the two methods was statistically significant (P < 0.015). Other variables examined, including the age and sex of the patients and the reasons for ventricular drainage, were not associated with an increased rate of infection. Most infections from either method were caused by a coagulase negative staphylococcus. The average duration of ventricular drainage before identification of positive cultures was 5.7 days for Rickham reservoirs and 6.0 days for ventriculostomies.     

浅析《野草》的版画特征

鲁迅先生一生热爱美术作品,对版画中木刻兴趣尤甚.<野草>作为其"写心之作",亦呈现出一些与木刻版画一致的审美特征:一是具有木刻版画的色彩特征,多对比、多冷色,有阴郁的美感;二是具有木刻版画的力度特征,环境描写、人物刻画处处刀锋毕现,遒劲有力,有一种"力之美".     

四辊破碎机车刀架的改造

针对四辊破碎机车刀架车削中存在的几个问题,详细介绍了电动车刀架的结构和工作原理,建立主要设计参数的数学表达式,并进行适当的分析。改造后,这种电动车刀架运行平稳、可靠、方便、省力,取得了预期的效果。     

Effect of antibiotics of chemotaxis of human leukocytes

The effect of 20 different antibiotics on chemotaxis by human neutrophils was studied. Human leukocytes incubated with chloramphenicol, rifampin, sodium fusidate, and tetracyclines in vitro showed markedly depressed migration. The mechanisms by which these antibiotics affect leukotaxis are discussed.