Ultrafine particles from electric appliances and cooking pans: experiments suggesting desorption/nucleation of sorbed organics as the primary source

Ultrafine particles are observed when metal surfaces, such as heating elements in electric appliances, or even empty cooking pans, are heated. The source of the particles has not been identified. We present evidence that particles >10 nm are not emitted directly from the heating elements or the metal surfaces. Using repeated heating of an electric burner, several types of cooking pans, and a steam iron, the increase in the number of particles (>10 nm) can be reduced to 0. After the devices are exposed to indoor air for several hours or days, subsequent heating results in renewed particle production, suggesting that organic matter has sorbed on their surfaces. Also, after a pan has been heated to the point that no increase in particles is observed, washing with detergent results in copious production of particles the next time the pan is heated. These observations suggest that detergent residue and organics sorbed from indoor air are the sources of the particles. We hypothesize that organic compounds are thermally desorbed from the hot surface as gaseous molecules; as they diffuse from the hot air near the pan into cooler air, selected compounds exceed their saturation concentration and nucleation occurs.     

Characterizing peak exposure of secondhand smoke using a real-time PM2.5 monitor

Although short-duration elevated exposures (peak exposures) to pollutants may trigger adverse acute effects, epidemiological studies to understand their influence on different health effects are hampered by lack of methods for objectively identifying peaks. Secondhand smoke from cigarettes (SHS) in the residential environment can lead to peak exposures. The aim of this study was to explore whether peaks in continuous PM_2.5 data can indicate SHS exposure. A total of 41 children (21 with and 20 without SHS exposure based on self-report) from 28 families in New York City (NY, USA) were recruited. Both personal and residential continuous PM_2.5 monitoring were performed for five consecutive days using MicroPEM sensors (RTI International, USA). A threshold detection method based on cumulative distribution function was developed to identify peaks. When children were home, the mean accumulated peak area (APA) for peak exposures was 297 ± 325 hour*µg/m³ for children from smoking families and six times that of the APA from non-smoking families (~50 ± 54 hour*µg/m³). Average PM_2.5 mass concentrations for SHS exposed and unexposed children were 24 ± 15 µg/m³ and 15 ± 9 µg/m³, respectively. The average SHS exposure duration represents ~5% of total exposure time, but ~13% of children's total PM_2.5 exposure dose, equivalent to an additional 2.6 µg/m³ per day. This study demonstrated the feasibility of peak analysis for quantifying SHS exposure. The developed method can be adopted more widely to support epidemiology studies on impacts of short-term exposures.     

Size distribution and lung-deposited doses of particulate matter from household exposure to biomass smoke

Exposure to high concentrations of particulate matter (PM) is associated with a number of adverse health effects. However, it is unclear which aspects of PM are most hazardous, and a better understanding of particle sizes and personal exposure is needed. We characterized particle size distribution (PSD) from biomass-related pollution and assessed total and regional lung-deposited doses using multiple-path deposition modeling. Gravimetric measurements of kitchen and personal PM_2.5 (<2.5 µm in size) exposures were collected in 180 households in rural Puno, Peru. Direct-reading measurements of number concentrations were collected in a subset of 20 kitchens for particles 0.3-25 µm, and the continuous PSD was derived using a nonlinear least-squares method. Mean daily PM_2.5 kitchen concentration and personal exposure was 1205 ± 942 µg/m³ and 115 ± 167 µg/m³, respectively, and the mean mass concentration consisted of a primary accumulation mode at 0.21 µm and a secondary coarse mode at 3.17 µm. Mean daily lung-deposited surface area (LDSA) and LDSA during cooking were 1009.6 ± 1469.8 µm²/cm³ and 10,552.5 ± 8261.6 µm²/cm³, respectively. This study presents unique data regarding lung deposition of biomass smoke that could serve as a reference for future studies and provides a novel, more biologically relevant metric for exposure-response analysis compared to traditional size-based metrics.     

Influencing factors of carbonyl compounds and other VOCs in commercial airliner cabins: On-board investigation of 56 flights

Volatile organic compounds (VOCs) as a non-negligible aircraft cabin air quality (CAQ) factor influence the health and comfort of passengers and crew members. On-board measurements of carbonyls (short-chain (C₁-C₆)) and other volatile organic compounds (VOCs, long-chain (C₆-C₁₆)) with a total of 350 samples were conducted in 56 commercial airliner cabins covering 8 aircraft models in this study. The mean concentration for each individual carbonyl compound was between 0.3 and 8.3 μg/m³ (except for acrolein & acetone, average = 20.7 μg/m³) similar to the mean concentrations of other highly detected VOCs (long-chain (C₆-C₁₆), 97% of which ranged in 0–10 μg/m³) in aircraft cabins. Formaldehyde concentrations in flights were significantly lower than in residential buildings, where construction materials are known formaldehyde sources. Acetone is a VOC emitted by humans, and its concentration in flights was similar to that in other high-occupant density transportation vehicles. The variation of VOC concentrations in different flight phases of long-haul flights was the same as that of CO₂ concentration except for the meal phase, which indicates the importance of cabin ventilation in diluting the gaseous contaminants, while the sustained and slow growth of the VOC concentrations during the cruising phase in short-haul flights indicated that the ventilation could not adequately dilute the emission of VOCs. For the different categories of VOCs, the mean concentration during the cruising phase of benzene series, aldehydes, alkanes, other VOCs (detection rate > 50%), and carbonyls in long-haul flights was 44.2 µg/m³, 17.9 µg/m³, 18.6 µg/m³, 31.5 µg/m³, and 20.4 µg/m³ lower than those in short-haul flights, respectively. Carbonyls and d-limonene showed a significant correlation with meal service (p < 0.05). Unlike the newly decorated rooms or new vehicles, the inner materials were not the major emission sources in aircraft cabins. Practical Implications.

• The on-board measurements of 56 flights enrich the VOC database of cabin environment, especially for carbonyls. The literature review of carbonyls in the past 20 years contributes to the understanding the current status of cabin air quality (CAQ).
• The analysis of VOC concentration variation for different flight phases, flight duration, and aircraft age lays a foundation for exploring effective control methods, including ventilation and purification for cabin VOC pollution.
• The enriched VOC data is helpful to explore the key VOCs of aircraft cabin environment and to evaluate the acute/chronic health exposure risk of pollutants for passengers and crew members.

     

Concurrent assessment of personal,indoor, and outdoor PM2.5 and PM1 levels and source contributions using novel low-cost sensing devices

The intensity, frequency, duration, and contribution of distinct PM_2.5 sources in Asian households have seldom been assessed; these are evaluated in this work with concurrent personal, indoor, and outdoor PM_2.5 and PM₁ monitoring using novel low-cost sensing (LCS) devices, AS-LUNG. GRIMM-comparable observations were acquired by the corrected AS-LUNG readings, with R² up to 0.998. Twenty-six non-smoking healthy adults were recruited in Taiwan in 2018 for 7-day personal, home indoor, and home outdoor PM monitoring. The results showed 5-min PM_2.5 and PM₁ exposures of 11.2 ± 10.9 and 10.5 ± 9.8 µg/m³, respectively. Cooking occurred most frequently; cooking with and without solid fuel contributed to high PM_2.5 increments of 76.5 and 183.8 µg/m³ (1 min), respectively. Incense burning had the highest mean PM_2.5 indoor/outdoor (1.44 ± 1.44) ratios at home and on average the highest 5-min PM_2.5 increments (15.0 µg/m³) to indoor levels, among all single sources. Certain events accounted for 14.0%-39.6% of subjects’ daily exposures. With the high resolution of AS-LUNG data and detailed time-activity diaries, the impacts of sources and ventilations were assessed in detail.     

The effect of fuel area size on behavior of fires in a reduced-scale single-track railway tunnel

A set of experiments was carried out in a 1/9 reduced-scale single-track railway tunnel to investigate the effect of fuel area size on the temperature distribution and behavior of fires in a tunnel with natural ventilation. Methanol pool fires with four different fuel areas 0.6 × 0.3 m² (1 pan), 1.2 × 0.3 m² (2 pans), 2.4 × 0.3 m² (4 pans) and 3.6 × 0.3 m² (6 pans), were used in these experiments. Data were collected on temperatures, radiative heat flux and mass loss rates. The temperature distribution and smoke layer in the tunnel, along with overflow dimensions and radiant heat at the tunnel entrance were analyzed. The results show that as the fuel area enlarges, the fire gradually becomes ventilation-controlled and the ceiling temperature over the center of fire source declines. Burning at the central region of fire source is depressed due to lack of oxygen. This makes the temperature distribution along the tunnel ceiling change from a typical inverted V-shape to an M-shape. As observed in the experiments, a jet flame appeared at tunnel entrances and both the size and temperature of the flame increased with the enlargement of fuel area leading to a great threat to firefighters and evacuees in actual tunnel fires.     

Comparison of next-generation portable pollution monitors to measure exposure to PM2.5 from household air pollution in Puno,Peru

Assessment of personal exposure to PM_2.5 is critical for understanding intervention effectiveness and exposure-response relationships in household air pollution studies. In this pilot study, we compared PM_2.5 concentrations obtained from two next-generation personal exposure monitors (the Enhanced Children MicroPEM or ECM; and the Ultrasonic Personal Air Sampler or UPAS) to those obtained with a traditional Triplex Cyclone and SKC Air Pump (a gravimetric cyclone/pump sampler). We co-located cyclone/pumps with an ECM and UPAS to obtain 24-hour kitchen concentrations and personal exposure measurements. We measured Spearmen correlations and evaluated agreement using the Bland-Altman method. We obtained 215 filters from 72 ECM and 71 UPAS co-locations. Overall, the ECM and the UPAS had similar correlation (ECM ρ = 0.91 vs UPAS ρ = 0.88) and agreement (ECM mean difference of 121.7 µg/m³ vs UPAS mean difference of 93.9 µg/m³) with overlapping confidence intervals when compared against the cyclone/pump. When adjusted for the limit of detection, agreement between the devices and the cyclone/pump was also similar for all samples (ECM mean difference of 68.8 µg/m³ vs UPAS mean difference of 65.4 µg/m³) and personal exposure samples (ECM mean difference of −3.8 µg/m³ vs UPAS mean difference of −12.9 µg/m³). Both the ECM and UPAS produced comparable measurements when compared against a cyclone/pump setup.     

Biological and environmental exposure monitoring of volatile organic compounds among nail technicians in the Greater Boston area

Nail technicians are exposed to volatile organic compounds (VOCs) from nail products, but no studies have previously measured VOC biomarkers for these workers. This study of 10 nail technicians aimed to identify VOCs in nail salons and explore relationships between air concentrations and biomarkers. Personal and area air samples were collected using thermal desorption tubes during a work shift and analyzed using gas chromatography/mass spectrometry (GC/MS) for 71 VOCs. Whole blood samples were collected pre‐shift and post‐shift, and analyzed using GC/MS for 43 VOCs. Ventilation rates were determined using continuous CO₂ measurements. Predominant air VOC levels were ethyl methacrylate (median 240 µg/m³), methyl methacrylate (median 205 µg/m³), toluene (median 100 µg/m³), and ethyl acetate (median 639 µg/m³). Blood levels were significantly higher post‐shift than pre‐shift for toluene (median pre‐shift 0.158 µg/L and post‐shift 0.360 µg/L) and ethyl acetate (median pre‐shift <0.158 µg/L and post‐shift 0.510 µg/L); methacrylates were not measured in blood because of their instability. Based on VOCs measured in these seven nail salons, we estimated that emissions from Greater Boston area nail salons may contribute to ambient VOCs. Ventilation rates did not always meet the ASHRAE guideline for nail salons. There is a need for changes in nail product formulation and better ventilation to reduce VOC occupational exposures.     

Accumulation of gas‐phase methamphetamine on clothing,toy fabrics,and skin oil

To better understand methamphetamine exposure and risk for occupants of former residential clandestine methamphetamine laboratories, we measured the dynamic accumulation of methamphetamine in skin oil, cotton and polyester (PE) clothing, upholstery, and toy fabric (substrates) exposed to 15–30 ppb (91–183 μg/m³) neutral methamphetamine in air for up to 60 days. The average equilibrium partition coefficients at 30% RH, in units of μg of methamphetamine per gram of substrate per ppb, are 3.0 ± 0.2 for a PE baby blanket, 5.6 ± 3.5 for a PE fabric toy, 3.7 ± 0.2 for a PE shirt, 18.3 ± 8.0 for a PE/cotton upholstery fabric, and 1200 ± 570 in skin oil. The partition coefficients at 60% RH are 4.5 ± 0.4, 5.2 ± 2.1, 4.5 ± 0.6, 36.1 ± 3.6, and 1600 ± 1100 μg/(g ppb), respectively. There was no difference in the partition coefficient for a clean and skin‐oil‐soiled cotton shirt [15.3 ± 2.1 μg/(g ppb) @ 42 days]. Partition coefficients for skin oil may be sensitive to composition. ‘Mouthing’ of cloth is predicted to be the dominant exposure pathway [60 μg/(kg body weight*ppb)] for a toddler in former meth lab, and indoor air concentrations would have to be very low (0.001 ppb) to meet the recommended reference dose for children.     

A recurrent neural network using historical data to predict time series indoor PM2.5 concentrations for residential buildings

Due to the severe outdoor PM2.5 pollution in China, many people have installed air-cleaning systems in homes. To make the systems run automatically and intelligently, we developed a recurrent neural network (RNN) that uses historical data to predict the future indoor PM2.5 concentration. The RNN architecture includes an autoencoder and a recurrent part. We used data measured in an apartment over the course of an entire year to train and test the RNN. The data include indoor/outdoor PM2.5 concentration, environmental parameters and time of day. By comparing three different input strategies, we found that a strategy employing historical PM2.5 and time of day as inputs performed best. With this strategy, the model can be applied to predict the relatively stable trend of indoor PM2.5 concentration in advance. When the input length is 2 h and the prediction horizon is 30 min, the median prediction error is 8.3 µg/m³ for the whole test set. For times with indoor PM2.5 concentrations between (20,50] µg/m³ and (50,100] µg/m³, the median prediction error is 8.3 and 9.2 µg/m³, respectively. The low prediction error between the ground-truth and predicted values shows that the RNN can predict indoor PM2.5 concentrations with satisfactory performance.     

Real-time measurements of PM2.5 and ozone to assess the effectiveness of residential indoor air filtration in Shanghai homes

Portable air cleaners are increasingly used in polluted areas in an attempt to reduce human exposure; however, there has been limited work characterizing their effectiveness at reducing exposure. With this in mind, we recruited forty-three children with asthma from suburban Shanghai and deployed air cleaners (with HEPA and activated carbon filters) in their bedrooms. During both 2-week filtration and non-filtration periods, low-cost PM_2.5 and O₃ air monitors were used to measure pollutants indoors, outdoors, and for personal exposure. Indoor PM_2.5 concentrations were reduced substantially with the use of air cleaners, from 34 ± 17 to 10 ± 8 µg/m³, with roughly 80% of indoor PM_2.5 estimated to come from outdoor sources. Personal exposure to PM_2.5 was reduced from 40 ± 17 to 25 ± 14 µg/m³. The more modest reductions in personal exposure and high contribution of outdoor PM_2.5 to indoor concentrations highlight the need to reduce outdoor PM_2.5 and/or to clean indoor air in multiple locations. Indoor O₃ concentrations were generally low (mean = 8±4 ppb), and no significant difference was seen by filtration status. The concentrations of pollutants and the air cleaner effectiveness were highly variable over time and across homes, highlighting the usefulness of real-time air monitors for understanding individual exposure reduction strategies.     

Probable aerosol transmission of SARS-CoV-2 in a poorly ventilated courtroom

There is increasing evidence of SARS-CoV-2 transmission via aerosol; the number of cases of transmission via this route reported in the literature remains however limited. This study examines a case of clustering that occurred in a courtroom, in which 5 of the 10 participants were tested positive within days of the hearing. Ventilation loss rates and dispersion of fine aerosols were measured through CO₂ injections and lactose aerosol generation. Emission rate and influencing parameters were then computed using a well-mixed dispersion model. The emission rate from the index case was estimated at 130 quanta h⁻¹ (interquartile (97–155 quanta h⁻¹). Measured lactose concentrations in the room were found relatively homogenous (n = 8, mean 336 µg m⁻³, SD = 39 µg m⁻³). Air renewal was found to play an important role for event durations greater than 0.5 h and loss rate below 2–3 h⁻¹. The estimated emission rate suggests a high viral load in the index case and/or a high SARS-CoV-2 infection coefficient. High probabilities of infection in similar indoor situations are related to unfavorable conditions of ventilation, emission rate, and event durations. Source emission control appears essential to reduce aerosolized infection in events lasting longer than 0.5 h.     

Health risk assessment of volatile organic compounds at daycare facilities

Children are particularly vulnerable to many classes of the volatile organic compounds (VOCs) detected in indoor environments. The negative health impacts associated with chronic and acute exposures of the VOCs might lead to health issues such as genetic damage, cancer, and disorder of nervous systems. In this study, 40 VOCs including aldehydes and ketones, aliphatic hydrocarbons, esters, aromatic hydrocarbons, cyclic terpenes, alcohols, and glycol ethers were identified and qualified in different locations at the University of Missouri (MU) Child Development Laboratory (CDL) in Columbia, Missouri. Our results suggested that the concentrations of the VOCs varied significantly among classrooms, hallways, and playground. The VOCs emitted from personal care and cleaning products had the highest indoor levels (2-ethylhexanol-1, 3-carene, homomenthyl salicylate with mean concentration of 5.15 µg/m³, 1.57 µg/m³, and 1.47 µg/m³, respectively). A cancer risk assessment was conducted, and none of the 95th percentile dose estimates exceeded the age-specific no significant risk levels (NSRL) in all classrooms. Dimensionless toxicity index scores were calculated for all VOCs using a novel web-based framework called Toxicological Prioritization Index (ToxPi), which integrates multiple sources of toxicity data. According to the method, homomenthyl salicylate, benzothiazole, 2-ethylhexyl salicylate, hexadecane, and tridecane exhibited diverse toxicity profiles and ranked as the five most toxic indoor VOCs. The findings of this study provide critical information for policy makers and early education professionals to mitigate the potentially negative health impacts of indoor VOCs in the childcare facilities.     

Characterization of decay and emission rates of ultrafine particles in indoor ice rink

The purposes of this study were to determine indoor ultrafine particle (UFP, diameter <100 nm) levels in ice rinks and to characterize UFP decay and emission rates. All 15 public ice rinks in Seoul were investigated for UFP and carbon monoxide (CO) concentrations. Three ice rinks did not show peaks in UFP concentrations, and one ice rink used two resurfacers simultaneously. High peaks of UFP and CO concentrations were observed when the resurfacer was operated. The average air change rate in the 11 ice rinks was 0.21 ± 0.13/h. The average decay rates of UFP number concentrations measured by the P‐Trak and DiSCmini were 0.54 ± 0.21/h and 0.85 ± 0.34/h, respectively. The average decay rate of UFP surface area concentration was 0.33 ± 0.15/h. The average emission rates of UFP number concentrations measured by P‐Trak and DiSCmini were 1.2 × 10¹⁴ ± 6.5 × 10¹³ particles/min and 3.3 × 10¹⁴ ± 2.4 × 10¹⁴ particles/min, respectively. The average emission rate of UFP surface area concentration was 3.1 × 10¹¹ ± 2.0 × 10¹¹ μm²/min. UFP emission rate was associated with resurfacer age. DiSCmini measured higher decay and emission rates than P‐Trak due to their different measuring mechanisms and size ranges.     

Real-time air monitoring of occupational exposures to particulate matter among hairdressers in Maryland: A pilot study

Hairdressers are exposed to particulate matter (PM), a known air pollutant linked to adverse health effects. Still, studies on occupational PM exposures in hair salons are sparse. We characterized indoor air PM concentrations in three salons primarily serving an African/African American (AA) clientele, and three Dominican salons primarily serving a Latino clientele. We also assessed the performance of low-cost sensors (uRAD, Flow, AirVisual) by comparing them to high-end sensors (DustTrak) to conduct air monitoring in each salon over 3 days to quantify work shift concentrations of PM_2.5, respirable PM (RPM), and PM₁₀. We observed high spatial and temporal variability in 30-min time-weighted average (TWA) RPM concentrations (0.18–5518 μg/m³). Readings for the uRAD and AirVisual sensors were highly correlated with the DustTrak (R² = 0.90–0.99). RPM 8-hour TWAs ranged from 18 to 383 µg/m³ for AA salons, and 9–2115 µg/m³ for Dominican salons. Upper 95th percentiles of daily RPM exposures ranged from 439 to 2669 µg/m³. The overall range of 30-min TWA PM_2.5 and PM₁₀ concentrations was 0.13–5497 and 0.36-,541 μg/m³, respectively. Findings suggest that hairdressers could be overexposed to RPM during an 8-hour shift. Additional comprehensive monitoring studies are warranted to further characterize temporal and spatial variability of PM exposures in this understudied occupational population.     

Exposure to fine,ultrafine particles and black carbon in two preschools in nur-sultan city of kazakhstan

Children in preschools were studied as an exceptionally vulnerable group to lung diseases due to their immature immune system. Few data are available in the literature addressing the exposure of children in preschools to ultrafine (>10 nm) particles. Exposure of children to fine, ultrafine (10 nm–1 µm) particles and black carbon particles present inside and near two preschools in Nur-Sultan, Kazakhstan, during Fall 2019 was investigated. For Preschool I, the average daily (6 h) indoor (outdoor) PM₁, PM_2.5, and PM₁₀ concentrations over three-week measurements were 15.0 (SD 12.5) µg/m³, 34.6 (SD 35.1) µg/m³, and 47.2 (SD 45.2) µg/m³, respectively. Average indoor UFP concentrations (>10.0 nm) including candle burning events were 5.20 × 10³ (SD 8.80 × 10³) particles/cm³, with the background UFP concentration to be 3.30 × 10³ (SD 1.80 × 10³) particles/cm³. In Preschool II, the average UFP concentration (>30.0 nm) in the morning and afternoon was 3.94 × 10³ (SD 5.34 × 10²) and 3.36 × 10³ (SD 1.90 × 10³) particles/cm³, respectively. Indoor black carbon (BC) concentrations were correlated with the outdoor smoking activity. The major sources of the indoor particles in the preschools were dust resuspension, candle burning, and infiltrated outdoor particles.     

Occupational exposure and health risks of volatile organic compounds of hotel housekeepers: Field measurements of exposure and health risks

Hotel housekeepers represent a large, low-income, predominantly minority, and high-risk workforce. Little is known about their exposure to chemicals, including volatile organic compounds (VOCs). This study evaluates VOC exposures of housekeepers, sources and factors affecting VOC levels, and provides preliminary estimates of VOC-related health risks. We utilized indoor and personal sampling at two hotels, assessed ventilation, and characterized the VOC composition of cleaning agents. Personal sampling of hotel staff showed a total target VOC concentration of 57 ± 36 µg/m³ (mean ± SD), about twice that of indoor samples. VOCs of greatest health significance included chloroform and formaldehyde. Several workers had exposure to alkanes that could cause non-cancer effects. VOC levels were negatively correlated with estimated air change rates. The composition and concentrations of the tested products and air samples helped identify possible emission sources, which included building sources (for formaldehyde), disinfection by-products in the laundry room, and cleaning products. VOC levels and the derived health risks in this study were at the lower range found in the US buildings. The excess lifetime cancer risk (average of 4.1 × 10⁻⁵) still indicates a need to lower exposure by reducing or removing toxic constituents, especially formaldehyde, or by increasing ventilation rates.     

Quantitative filter forensics: Size distribution and particulate matter concentrations in residential buildings

We applied filter forensics, the analysis of dust from the heating, ventilation, and air-conditioning (HVAC) filters, to measure particle size distribution in 21 residences in Toronto, Canada over a year. Four filters with different nominal efficiencies (Minimum Efficiency Reporting Value (MERV) 8–14 from ASHRAE Standard 52.2) were deployed in each residence each for three months, while the effective filtration volumes (the product of flow rate, runtime, and in-situ filter efficiency) were characterized over each filter lifetime. Using extraction and laser diffraction, we found that approximately 90% of the volumetric distributions were >10 µm and the volume median diameter (VMD) ranged from 23.4 to 75.1 µm. Using quantitative filter forensics (QFF), total suspended particle (TSP) concentrations ranged from 2.9 to 823.7 µg/m³ (median = 89.8 µg/m³) with a moderate correlation with the content of TSP on the filters (in terms of g) and with the TSP effective filtration volume (m³) indicating the importance of both filter forensics and HVAC metadata parameters to QFF concentration estimates. There was no strong correlation between PM₁₀ or PM_2.5 concentrations and hourly airborne particle number concentrations measured by low-cost sensors suggesting an evaluation of QFF is warranted, particularly for the exploration of smaller particles.     

Association between indoor formaldehyde exposure and asthma: A systematic review and meta-analysis of observational studies

About 339 million people worldwide are suffering from asthma. We aimed to investigate whether exposure to formaldehyde (FA) is associated with asthma, which could provide clues for preventive and mitigation actions. This article provides a systematic review and meta-analysis of observational studies to assess the association between indoor FA exposure and the risk of asthma in children and adults. An electronic search of PubMed, Embase, and Web of Science was performed to collect all relevant studies published before January 1, 2020, and a total of 13 papers were included in this meta-analysis. A random-effect model was conducted to calculate the pooled odds ratio (OR) between FA exposure and asthma. We found that each 10 µg/m³ increase in FA exposure was significantly associated with a 10% increase in the risk of asthma in children (OR = 1.10, 95% confidence interval = 1.00-1.21). We sorted the FA concentrations reported in the selected articles and categorized exposure variables into low (FA ≤ 22.5 µg/m³) and high exposure (FA > 22.5 µg/m³) according to the median concentration of FA. In the high-exposure adult group, FA exposure may also be associated with an increased risk of asthma (OR = 1.81, 95% CI = 1.18-2.78).     

Characterization and exposure assessment of household fine particulate matter pollution in China

Household fine particulate matter (PM_2.5) pollution greatly impacts residents' health. To explore the current national situation of household PM_2.5 pollution in China, a study was conducted based on literature published from 1998 to 2018. After extracting data from the literature in conformity with the requirements, the nationwide household-weighted mean concentration of household PM_2.5 (HPL) was calculated. Subgroup analyses of spatial, geographic, and temporal differences were also done. The estimated overall HPL in China was 132.2 ± 117.7 μg/m³. HPL in the rural area (164.3 ± 104.5 μg/m³) was higher than that in the urban area (123.9 ± 122.3 μg/m³). For HPLs of indoor sampling sites, the kitchen was the highest, followed by the bedroom and living room. There were significant differences of geographic distributions. The HPLs in the South were higher than the North in four seasons. The inhaled dose of household PM_2.5 among school-age children differed from provinces with the highest dose up to 5.9 μg/(kg·d). Countermeasures should be carried out to reduce indoor pollution and safeguard health urgently.