Serial recall by schizophrenic and affective patients during and after psychotic episodes.

Eight schizophrenics (mean age 27.3 yrs), 8 depressed patients (mean age 33.1 yrs), and 8 normal controls (mean age 27 yrs) completed the MMPI and were asked to recall short word strings in both the presence and absence of distraction. Results show a differential cognitive deficit among schizophrenics both before and after a general improvement in their level of adjustment. That is, despite an overall improvement in their accuracy of recall prior to discharge, their performance continued to be impaired relative to depressed and normal Ss on the words presented in the 1st serial position. A tendency toward greater distractibility among schizophrenics failed to reach statistical significance at both points of assessment. Further substantiation of such stable forms of cognitive impairment may facilitate the identification of individuals who are vulnerable to the development of schizophrenia and may shed light on the adjustment problems that many chronic patients continue to experience after discharge from the hospital. (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of intramodal and crossmodal stimulus diversity on the reaction time of chronic schizophrenics.

Compared 16 chronic schizophrenics (mean age 42.7 yrs), 16 alcoholic inpatients (mean age 37.6 yrs), and 16 healthy Ss (mean age 36.9 yrs) with respect to their RTs to stimuli from 1 (ipsimodal condition) or 2 (crossmodal condition) modalities. In the ipsimodal condition, a low-pitched sound presented to one ear and a high-pitched sound presented to the other ear served as imperative stimuli, alternating randomly. In the crossmodal condition, a light or a sound was presented. In responding to the sound imperative stimuli, schizophrenics were more retarded than were comparison groups when the preceding imperative stimulus was a light or a different sound, relative to when it was the same sound. With the inclusion of warning stimuli of either modality into the crossmodal condition, both comparison groups were more retarded than were schizophrenics when the preceding imperative stimulus was a light, relative to when it was the same sound. (20 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Selective attention in schizophrenic and manic psychoses: The effect of distraction on information processing.

Attempted to identify the general level of cognitive processing that is especially vulnerable to distraction in schizophrenia. The extent and nature of distraction were compared in 12 schizophrenic patients (mean age, 27.8 yrs), 12 manic patients (mean age, 28.2 yrs), and 12 controls (mean age, 26.7 yrs) using neutral and distractor word-span tests. Also, all patients were evaluated by the Nurse's Observation Scale for Inpatient Evaluation, and 10, 11, and 12 controls, schizophrenics, and manics, respectively, completed the MMPI. On one set of tests, serial position curves indicated that in the presence of distraction the overall deterioration in schizophrenics' performance reflected their tendency to forget early, and not late, items in the lists. On a 2nd set of tests, both schizophrenics and manics were abnormally distracted, regardless of the speed of presentation. Although the controls were also somewhat distracted by irrelevant words, their impairment was significantly diminished at slower rates of presentation. With distraction, schizophrenics and manics were less able to use the extra time in slow presentations for active mental operations such as rehearsal. Both groups made more intrusive errors than normal Ss. Results indicate that distraction interferes with schizophrenics' and manics' information processing at some level beyond the comparatively passive stages of recognition and sensory storage. Problems in selective attention seem to be more closely related to thought disorder than to diagnostic categories. (25 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Lexical cohesion and formal thought disorder during and after psychotic episodes.

Compared speech samples obtained from 10 schizophrenics (mean age 28 yrs), 11 manics (mean age 26.2 yrs), 11 schizoaffectives (mean age 25.8 yrs), and 10 normals (mean age 33.6 yrs) for the amount of lexical cohesion both within and between clauses. Two speech samples were obtained for each patient: one shortly after admission to a psychiatric hospital and another several weeks following discharge. All psychiatric patients showed evidence of formal thought disorder at admission, and all 3 groups showed a significant decline in the extent of thought disorder at follow-up. There were no differences between groups with regard to between-clause lexical cohesion at either point in time. Within-clause lexical cohesion did distinguish among the psychiatric groups at the 1st assessment interval; schizophrenics showed less within-clause lexical cohesion than the manics or schizoaffective patients. The manics and the schizoaffectives showed a significant decline in the amount of within-clause lexical cohesion from initial assessment to follow-up. The schizophrenics exhibited a modest decline in the amount of between-clause lexical cohesion. Results indicate that diagnostic differences in lexical cohesion depended on the specificity of the measure and suggest that there are subtle differences between the forms of verbal-communication impairment observed in schizophrenic and affective disorders. (9 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Length of hospitalization and rate of readmission of paranoid and nonparanoid schizophrenics.

The underrepresentation of paranoids-a group that manifests less psychological deficit-in hospitalized chronic schizophrenic cohorts has been cited as a source of sampling bias in behavioral studies comparing acute and chronic schizophrenics. The sampling bias hypothesis assumes this underrepresentation to be due to the better social prognosis of paranoid patients. The present study examined hospitalization and follow-up records for 1,249 consecutive inpatient admissions. Consistent with the sampling bias assumption, paranoids were found to be hospitalized more briefly than nonparanoids and to experience fewer rehospitalizations 1, 3, and 5 yrs after discharge. As expected, the social prognosis of 1st admissions was found to be more favorable than that of readmissions, independently of paranoid symptomatology. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Disappearance of paranoid symptoms with chronicity.

Investigated the finding of a reduced proportion of paranoids in chronic samples. Whether this change is due to the disappearance of paranoid patients or of paranoid symptomatology is unclear. Data from 50 multi-admitted paranoid schizophrenics firmly support the notion that paranoid symptomatology disappears. Although half of the patients remained paranoid across 10 yrs of illness, the other half changed to nonparanoid status around the 3rd hospitalization and about 6 yrs after 1st admission. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Age on first hospitalization of schizophrenics: A developmental approach.

Compared ages at 1st hospitalization of 3 groups of schizophrenics: 64 males in a VA hospital and 60 male and 60 female patients in a state hospital. Paranoid Ss were approximately 8 yrs older when first admitted than the nonparanoids. In both diagnostic categories males were hospitalized about 5 yrs earlier than females. Working females with a diagnosis of paranoia were hospitalized approximately 10 yrs later than the paranoid females who remained at home and the nonparanoid females of either employment status. State hospital males were younger on 1st admission than VA hospital males. The ages of the 2 diagnostic groups in the VA were comparable, whereas in the state hospital the nonparanoid group was younger than the paranoid group by about 8 yrs. The need to pay greater attention to the differences between schizophrenic males and females and to scrutinize more closely differences between state and VA hospital patients is emphasized. (48 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Features that distinguish the smooth-pursuit eye-tracking performance of schizophrenic, affective-disorder, and normal individuals.

Examined the eye-tracking records of 25 schizophrenic (mean age 37.6 yrs), 25 unipolar (mean age 37.9 yrs), 24 bipolar (mean age 36 yrs), and 46 medical control (mean age 35 yrs) patients. All the psychiatric patients were in symptom remission. All three psychiatric groups produced more oscillations than controls, and spiky tracking was correlated with poor performance as indexed by the production of large saccades. Schizophrenics did, however, produce smaller saccades and tracked with more phase lag than did each of the other groups. Results suggest that the smooth-pursuit system of schizophrenics is functionally different from that of normal people. Use of the phase lag as a potential marker of schizophrenia is discussed. (33 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Expectancies, mood, and performance of depressed and nondepressed psychiatric inpatients on chance and skill tasks.

The learned helplessness model of depression predicts that, compared with nondepressed patients, depressed patients will demonstrate psychomotor deficits, provide lower subjective evaluations of their performance, and perceive reinforcement in skill tasks as more response independent. These predictions were tested in 32 depressed (mean age 35 yrs) and 32 nondepressed (mean age 38 yrs) psychiatric inpatients, who had been administered the Quick Test and the Beck Depression Inventory. Ss performed card- and peg-sorting tasks in which measures of performance, ratings of mood and expectancy of success, and subjective evaluations of performance were obtained under chance and skill reinforcement conditions. Although some support was obtained for the prediction that depressives provide lower evaluations of their performance than nondepressives, the other predictions were not supported. Comparisons between depressed and nondepressed schizophrenics indicate that the mood of depressed schizophrenics was especially sensitive to task outcome for both skill and chance conditions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Neuropsychological performance and positive and negative symptoms in schizophrenia.

Examined cognitive functions in 11 positive-symptom (mean age 36 yrs), 10 negative-symptom (mean age 33.8 yrs), and 23 mixed-symptom (mean age 31.4 yrs) schizophrenics; 15 bipolar patients (mean age 34.7 yrs); and 12 normal controls (mean age 34.8 yrs) to explore the relation between symptoms and performance. Ss were administered a neuropsychological test battery including the Purdue Pegboard, the Revised Visual Retention Test, and the Block Design subtest of the Wechsler Adult Intelligence Scale—Revised (WAIS—R). Group comparisons revealed generalized deficits in schizophrenics. Positive-symptom schizophrenics scored below normal Ss and negative-symptom Ss on 2 measures tapping verbal memory. Multiple regression analyses revealed that negative symptom ratings were inversely associated with performance on visual-motor tasks, whereas positive symptoms were inversely associated with verbal memory performance. Findings are not consistent with the notion that cognitive deficits are uniquely associated with negative symptoms. Instead, results suggest that there may be specific cognitive correlates of both the positive and negative symptom dimensions. (38 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Attribution style, the dexamethasone suppression test, and the diagnosis of melancholia in depressed inpatients.

Administered a measure of attribution style and a biological measure of the endogenous depressive subtype (the dexamethasone suppression test) to 50 depressed patients (mean age 36.04 yrs) during their 1st wk of hospitalization. Ss were also rated on a phenomenological index (DSM-III criteria for melancholia). Results show that attribution style was unrelated to either method used to identify the endogenous subtype. (39 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Speech competence in manic and schizophrenic psychoses: The association between clinically rated thought disorder and cohesion and reference performance.

Compared 20 thought-disordered (TD) manics and schizophrenics (mean age 31 yrs) to 20 manic and schizophrenic patients (mean age 31.25 yrs) without thought disorder (NTD) and to 10 normal Ss (mean age 30.9 yrs) normal on the rating scales of cohesion and reference performance in speech developed by S. R. Rochester and J. R. Martin (1979). TD manics and schizophrenics differed from NTD Ss and the normal group in their more frequent use of unclear references as well as in their less frequent use of effective cohesion and reference strategies. Speech elements of the TD Ss were classified into disordered and nondisordered segments, and the same natural language analysis was completed for each category of speech segments. Nondisordered speech segments of TD Ss were quite similar to the overall speech performance of NTD Ss and the normal group. There were no cohesion or reference performance differences between TD manics and TD schizophrenics in their disordered speech segments. Findings are interpreted as validation of the usefulness of the Rochester and Martin rating system for identifying aspects of speech performance that are related to clinically rated thought disorder. (22 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Schizophrenic thought disorders and impaired perspective.

Hypothesized that impaired perspective on the idiosyncracy of their own behavior is a central factor in the speech and thought pathology of schizophrenics and bizarre patients. 30 schizophrenic and 29 nonschizophrenic patients (mean age 25 yrs) rated the typicalness of their own and other patients' responses to proverbs. An index of perspective was calculated by correlating these ratings with trained judges' ratings of the idiosyncracy of the responses. Perspective on patients' own responses was significantly lower among schizophrenics and bizarre patients than among nonschizophrenics and nonbizarre patients. Poorer perspective occurred in patients' ratings of their own responses than in their ratings of other patients' responses. Results suggest that (a) loss of global perspective concerning the idiosyncracy of one's own verbalizations is closely associated with a tendency toward disordered speech. (b) Somewhat impaired perspective on what behavior is socially appropriate is common to all types of disturbed patients but is more severe in schizophrenics. (c) The impairment in schizophrenics is selective, involving difficulty in maintaining perspective on their own behavior, with better perspective when assessing others' behavior. (40 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A cross-sectional study of emotion recognition in schizophrenics.

48 hospitalized schizophrenics and 48 nonhospitalized normals were administered a test of emotion recognition that included photographs depicting facial expressions of 8 emotions. Ss were then given the Vocabulary test of the Wide Range Achievement Test. The groups were subdivided by age: children (8–22 yrs), adolescents (13–29 yrs), and adults (20–50 yrs). Patients and normals were matched on age, sex, and educational level. Normals were significantly better than schizophrenics at identifying all of the emotions, and this difference held across sex and age groups. Schizophrenics and normals did not differ in the types of errors they made. Findings are discussed in light of theories regarding social and emotional functioning in schizophrenics. (28 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Depression, working models of others, and relationship functioning.

Two studies examined depressives' working models of others and the relative contribution of these models and depression to relationship functioning. Respondents reported on their childhood relationships, adult attachment style, and relationship functioning. Study 1 compared 163 mildly depressed and nondepressed college women (aged 17–48 yrs), and Study 2 compared 25 married women recovering from clinical depression with 23 nondepressed married women (mean age 40 yrs for both groups). Mildly depressed college women evidenced greater preoccupation and fearful avoidance in romantic relationships than did nondepressed women; recovering depressed women evidenced greater fearful avoidance. In both studies, relationship functioning was predicted more strongly by adult attachment style than by depression status. Among college women, positive experiences with mother also were linked to better relationship functioning; however, attachment style and depression status mediated this effect. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Left hemisphere dysfunction and left hemisphere overactivation in schizophrenia.

Reports 2 experiments relating schizophrenia to functional brain asymmetry. In Exp I, 24 schizophrenics (mean age, 30.8 yrs) were compared to 24 matched controls (mean age, 37.3 yrs) on 2 tachistoscopic tasks (Syllable Test and Dot Location Test) designed to measure verbal and spatial information processing in the 2 hemispheres. Unlike the controls, the schizophrenics showed a right hemisphere superiority both on the verbal and on the spatial tests, indicating left hemisphere dysfunction in the initial processing of verbal information. In Exp II, lateral eye movements, as an index of contralateral hemispheric activation, were measured in a group of 24 paranoid schizophrenics (mean age, 28.9 yrs), 24 nonparanoid schizophrenics (mean age, 32.7 yrs), and 24 matched controls (mean age, 31.2 yrs). The eye movements were elicited by presenting the Ss with verbal neutral, verbal emotional, spatial neutral, and spatial emotional questions. The schizophrenics had significantly more rightward eye movement, compared to controls, regardless of question type, indicating left hemisphere overactivation. Results suggest that schizophrenia is associated with a pattern consisting of both left hemisphere dysfunction and overactivation. (63 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Defective interhemispheric transfer in schizophrenia.

Groups of schizophrenics, nurses, and psychiatric controls were trained to perform a manual shape discrimination task. The 20 schizophrenics included 17 outpatients and 3 short-term inpatients: 10 males (mean age 36 yrs) and 10 females (mean age 37.6 yrs). Nurse control Ss were 10 male (mean age 26.3 yrs) and 10 female (mean age 22 yrs) psychiatric nurses or student nurses. Psychiatric control Ss were 8 males (mean age 36.1 yrs) and 10 females (mean age 32.6 yrs). On both of the tasks included in the experiment, the schizophrenic group, but not the control groups, displayed defective intermanual transfer. The performances of the schizophrenics resembled those previously obtained with split-brain monkeys on similar tasks; therefore, it is concluded that the schizophrenics tested suffered from incomplete transfer of stereognostic shape information from 1 cerebral hemisphere to the other. Experiments suggesting poor interhemispheric transfer on auditory tasks in schizophrenics are discussed along with the possibility that certain schizophrenic symptoms are related to defective interhemispheric communication. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Development of a scale to measure intense ambivalence.

Developed a 45-item true–false scale to measure intense ambivalence using a procedure that ensured high internal consistency with minimal method variance. It has been argued that intense ambivalance is characteristic of Ss who are genetically predisposed to the development of schizophrenia. The scale was first validated by interviewing 72 (of 759 Ss who completed the scale) college students who scored high and in the normal range on the scale. Ss who scored high on the scale spontaneously reported feeling ambivalent and behaved ambivalently more often than low-scoring controls. The scale was then given to 85 schizophrenics (mean age 35.6 yrs), 30 hospitalized depressives (mean age 35.5 yrs), 192 psychology clinic patients (mean age 27.1 yrs), and 139 normal controls (mean age 31.3 yrs). As predicted, schizophrenics scored higher than controls; clinic clients scored in the middle range. Depressives scored the highest of all the groups. (40 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Multivariate cognitive performance levels and response styles among paranoid and nonparanoid schizophrenics.

Examined paranoid and nonparanoid schizophrenic performance on a battery of information processing measures spanning precategorical processing, short-term memory, and long-term memory. 20 paranoid (mean age 30.9 yrs) and 20 nonparanoid (mean age 29.3 yrs) schizophrenics and 40 normals (mean age 26.69 yrs) were administered the Symptom-Sign Inventory and the Psychotic-Neurotic Discriminator Scale. Multivariate analyses of the multiple processing indexes revealed 2 performance dimensions. The 1st represented "processing efficiency" maximally separating the paranoids and nonpatients with the nonparanoids falling in between. The 2nd dimension reflected a response style of propensity toward stating the presence of stimuli or stimulus properties, with the most extreme separation occurring between the paranoids (higher propensity) and nonparanoids. Though closer to the paranoids, the nonpatients fell between the 2 schizophrenic groups. Discussion draws on the bidimensional characterization of the paranoids and nonparanoids as well as on their differential performance on individual measures. (50 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)