共查询到18条相似文献,搜索用时 140 毫秒
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HPLC与AAS,AFS联用技术在元素化学形态分析中的应用 总被引:1,自引:0,他引:1
本文介绍了高效液相色谱与原子吸收光谱、原子荧光光谱的联用技术及其应用于元素化学形态分析的现状、前景及存在问题。着重论述了用于元素形态分析的高效液相色谱分离方法及联用接口。 相似文献
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ICP-MS相关联用技术在食品元素形态分析中的应用及进展 总被引:3,自引:0,他引:3
电感耦合等离子体质谱(ICP-MS)技术凭借其低检出限、多元素同时分析等优点,广泛应用于食品中的元素分析。随着分析技术的发展,以及元素的不同形态在物理、化学、营养、毒理等方面的显著差异,元素形态分析已经引起分析工作者的广泛关注。本工作对近年来ICP-MS技术与各种分离手段联用,在食品中砷、硒及锡等元素形态分析中的应用进行了综述,指出了ICP-MS 相关联用技术应用于食品元素形态分析时存在的问题,并对其未来的发展趋势进行了展望。 相似文献
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建立了使用毛细管电泳与电感耦合等离子体质谱联用技术(CE-ICP-MS)对5种形态的砷化合物砷甜菜碱(As B)、砷胆碱(As C)、三价砷(As3+)、二甲基砷(DMA)和一甲基砷(MMA)进行形态分析的实验方法。结果表明,使用摩尔体积比为4:1的50mmol/L H3BO3~12.5mmol/L Na2B4O7混合溶液作为缓冲溶液,在p H值为9.1,分离电压为18KV的实验条件下分析结果最为理想。5种砷化物的峰面积相对标准偏差(RSD)在5%以内,检出限(3S/N)为1.6ug/L~3.1ug/L。应用该方法成功地对虾肉中的砷化物进行了分析,回收率为88%~112%。该方法具有分析速度快、灵敏度高等优点,可用于虾肉样品中砷元素的形态分析。 相似文献
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联用技术应用于食品中铬形态分析方法概述 总被引:1,自引:0,他引:1
本文对近年来原子光谱、电感耦合等离子体质谱法(ICP-MS)与色谱联用技术在食品样品中铬元素形态分析中的应用进行概述,介绍联用技术离子色谱(IC)、高效液相色谱(HPLC)在形态分析中的应用。 相似文献
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原子吸收光谱法在元素形态分析方面的应用 总被引:4,自引:2,他引:4
元素形态分析已成为AAS发展的一个热点,是分析化学的一个重要发展领域。 本文评述了近年来原子吸收光谱法在元素形态分析方面的应用进展,包括化学法分析元 素形态,氢化物发生法分析元素形态,色谱-原子吸收光谱联用分析元素形态。 相似文献
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HPLC/ICP-MS在环境样品的痕量元素形态分析中的应用 总被引:10,自引:1,他引:10
综述了高效液相色谱-电感耦合等离子体质谱联用技术(HPLC/ICP-MS)的最新进展和工作特点,介绍了该技术在环境样品分析中的应用概况、接口类型和应用同位素稀释技术进行元素形态分析等。 相似文献
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ICP-MS技术及其应用 总被引:7,自引:0,他引:7
ICP—MS技术在分析能力上不仅可以覆盖传统的无机元素分析技术如CIPAES、CFAAS等的工作范围,可进行定性、半定量、定量分析,还可以进行同位素比测定,以及与不同的进样技术(如激光熔蚀)及分离技术(如HPLC,HPCE,GC)联用进行元素的形态、分布特性等的分析。ICP—MS已广泛应用于环境、半导体、医学,生物、冶金、地质科学、石油、核材料分析等领域。本文以实例说明ICP—MS技术在各分析领域的应用优点。 相似文献
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电感耦合等离子体质谱法在临床样品分析中的应用 总被引:4,自引:0,他引:4
本文对近年来电感耦合等离子体质谱法(ICP-MS)在临床样品微量元素及形态分析中的应用进行了综述,讨论了应用ICP-MS技术测定临床样品微量元素的三种处理和分析方法(直接稀释法,湿法消解法和微波消解法),列举了部分含量测定的实例。介绍了联用技术高效液相色谱(HPLC)、气相色谱(GC)、超临界流体色谱(SFC)和毛细管电泳(CE)在形态分析中的应用,指出了现存的问题,探讨了可能的解决方案。 相似文献
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Yuh-changSun 《质谱学报》2010,31(Z1):24-24
It is well known that the speciation, or chemical form, of metals governs its fate, toxicity, mobility, and bioavailability in environmental and biological systems. To assess these chemical properties and to accurately gauge their impact on human health and the environment, metals need to be characterized at the atomic level. To attain new information about environmental and biological effects of trace elements, new methodologies or modify conventional analytical methods is deemed as vital factor for the progress of bio- and environmental- studies. In view of the limitation on the analytical capability of single instrumental technique, analytical chemists can seldom rely on a single instrumental technique to analyze a sample with complicated matrix and analyte species with a variety of physico-chemical form. It is thus necessary to develop a technique which can fulfill ultratrace analyses of metal species down to the sub-g/L concentration range in complicated samples. Accordingly, the most important features of an analytical tool suitable for meeting the requirement of modern bio-analytical works are shorter temporal resolution, good selectivity and high sensitivity. For ultratrace elements measurements, ICP coupled with Mass Spectrometry (ICP-MS) has been considered as first priority option. Although the analytical sensitivity has been significantly improved by the technical advances in ICP-MS, instrumental limitations, such as difficulties in differentiating elemental species and removing matrix interferences caused by the concomitant salt, still remain in advanced analytical technologies. To satisfy the analytical requirements, the potency of hyphenating analytical separation techniques to mass spectrometers has been recognized. Basically, according to Hirschfeld1, the advantages brought about by coupling techniques are increasing the differentiating and separating power of analytical methods and synergism between methods. However, the design of the analytical system is difficult, owing to the complex composition of the real-world sample, the diversity of physicochemical forms of the element, their lability and low concentrations. For overcoming the abovementioned problems, attempts to couple ICP-MS with various types of chromatography for separation, as well as on-line sample pretreatment techniques for signal enhancement and matrix removal have been made. To expand the analytical capability, in this study, we developed several hyphenated systems by integrating the alternative photo-redox characteristic of nano-TiO2 into the interfacing device to convert both inorganic and organic metal-containing species to gaseous products that are favor for ICP-MS determination. Based on our experimental results, this presentation will describe the studied hyphenated methods which have been proven feasible for the analyses of trace elements and their chemical species in environmental and biological systems. 相似文献
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HPLC-ICP-MS hyphenated techniques were developed for the elemental speciation analysis. Different species of I, Br and Hg were successfully separated and determined. The linier dynamic ranges, the detection limits were discussed. The compound independent calibration (CIC) phenomenon for HPLC-ICP-MS techniques were found and its good potential in applications were discussed as example. 相似文献
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Metal-based anticancer agents are frequently used in the treatment of a wide variety of cancer types. The monitoring of these anticancer agents in biological samples is important to understand their pharmacokinetics, pharmacodynamics, and metabolism. In addition, determination of metals originating from anticancer agents is relevant to assess occupational exposure of health care personnel working with these drugs. The high sensitivity of inductively coupled plasma mass spectrometry (ICP-MS) has resulted in an increased popularity of this technique for the analysis of metal-based anticancer drugs. In addition to the quantitative analysis of the metal of interest in a sample, ICP-MS can be used as an ultrasensitive metal selective detector in combination with speciation techniques such as liquid chromatography. In the current review we provide a systematic survey of publications describing the analysis of platinum- and ruthenium-containing anticancer agents using ICP-MS, focused on the determination of total metal concentrations and on the speciation of metal compounds in biological fluids, DNA- and protein-adducts, and environmental samples. We conclude that ICP-MS is a powerful tool for the quantitative analysis of metal-based anticancer agents from multiple sample sources. 相似文献
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HPLC-ICP-MS hyphenated technique was used for the Se speciation analysis. Se-methylseleno L-cysteine (C4H9NO2Se) and DL-selenomethionine, (CH3Se(CH2)2CH(NH2)COOH) were successfully separated by both Ion-Pair HPLC and size exclusion chromatography-HPLC, then on-line measured by hyphenating with ICP-MS. The linier dynamic range better than 3 orders (from 5 μg/L to 500 μg/L for both Se species) were obtained for IP-HPLC-ICP-MS. The detection limits and the compound independent calibration (CIC) phenomenon for HPLC-ICP-MS were discussed. The good potential of HPLC-ICP-MS method were shown by the experiments for the se-speciation analysis. 相似文献