Are prosome particles formed by the disintegration of proteasomes?

Quail reticulocyte 19S "prosome" fractions isolated on sucrose density gradients contain two kinds of particles: cylindrical proteasomes and ferritin. When samples of this fraction are prepared for electron microscopy using the one-step stain protocol described in this paper, most of the particles have a rectangular image resembling the proteasome. However, when samples are prepared for electron microscopy using the two-step stain protocol described here, there are few rectangular images. Their place is taken by round particles that resemble the prosome. Thus it appears that the round, raspberry-shaped particles called prosomes and the ring-like proteasome particles may be artifacts of specimen preparation for electron microscopy. We propose that proteasome particles may disintegrate when prepared for electron microscopy by methods such as the two-step stain protocol and that prosome particles represent the component parts of the proteasome. Furthermore, based on the enhancement of proteasome images obtained using the one-step main protocol we propose that, instead of consisting of a stack of four rings, the proteasome is constructed of three components, i.e., a spherical central particle flanked by two flat hexagonal end caps.     

But is it good for the psychologists? Appraisal and status of DSM-III.

Presents a critical analysis of the 3rd edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III). Improvements over DSM-II are acknowledged; it is suggested, however, that problems with larger issues (e.g., multiaxial, diagnosis, operational criteria, and the medical model) overshadow these positive features. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are female managers quitters? The relationships of gender, promotions, and family leaves of absence to voluntary turnover.

This study examined the relationships of gender, promotions, and leaves of absence to voluntary turnover for 26,359 managers in a financial services organization. Using Cox regression analyses and controlling for human capital, the authors found that, contrary to their prediction, female managers' voluntary turnover rates were slightly lower than those of their male counterparts. Managers who had been promoted were less likely to resign than nonpromoted managers only if the promotion had occurred within the past 11 months, and promoted women were less likely to resign than promoted men. The authors also found that managers who had taken family leaves had higher voluntary turnover rates than managers who had not taken leaves, and among family leave takers, managers with graduate degrees were less likely to resign than managers with less education. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are the memories of older adults positively biased?

There is disagreement in the literature about whether a "positivity effect" in memory performance exists in older adults. To assess the generalizability of the effect, the authors examined memory for autobiographical, picture, and word information in a group of younger (17-29 years old) and older (60-84 years old) adults. For the autobiographical memory task, the authors asked participants to produce 4 positive, 4 negative, and 4 neutral recent autobiographical memories and to recall these a week later. For the picture and word tasks, participants studied photos or words of different valences (positive, negative, neutral) and later remembered them on a free-recall test. The authors found significant correlations in memory performance, across task material, for recall of both positive and neutral valence autobiographical events, pictures, and words. When the authors examined accurate memories, they failed to find consistent evidence, across the different types of material, of a positivity effect in either age group. However, the false memory findings offer more consistent support for a positivity effect in older adults. During recall of all 3 types of material, older participants recalled more false positive than false negative memories. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are estrogens carcinogenic during development of the testes?

Many chemicals in the environment mimic the female sex hormone, estrogen. Exposure to environmental estrogens during early fetal development was proposed by Sharpe & Skakkebaek as a potential risk factor for subsequent testicular disease, including neoplasia and poor semen quality. To understand the mechanisms of action of estrogenic chemicals during differentiation of the male genital tract, we have studied developmental exposure to the synthetic estrogen, diethylstilboestrol (DES). While DES is a much more potent estrogen than most environmental chemicals examined, several of these compounds share some of the same properties as DES, such as a relative lack of binding to serum estrogen carrying proteins. Prenatal exposure to DES is associated with poor semen quality, prostatic disease, cryptorchidism and testicular neoplasia in mice. A rare form of testicular cancer, rete testis carcinoma, was observed in five percent of male mice treated in utero with DES. We also demonstrated altered regulation of an estrogen responsive gene, lactotransferrin (LTF) in the seminal vesicles of treated mice, but not the controls. Likewise, LTF was irreversibly altered in the uteri of developmentally treated females; at the molecular level altered methylation of the gene appears to be involved, thus, providing a potential marker for hormonal effects during development. The induction of permanent or "imprinted" responses during the development of a relatively estrogen-free reproductive tract cell suggests that undifferentiated targets for estrogen action may be sites for subsequent growth and differentiation defects associated with neoplasia.     

Are morphological effects distinguishable from the effects of shared meaning and shared form?

Effects of orthographically and semantically related primes were compared with morphologically related primes in an immediate (Experiment 1) and a long-term (Experiment 2) lexical decision task. Morphological relatedness produced facilitation across a range of prime durations (32–300 ms) as well as when items intervened between prime and target, and its magnitude increased with prime duration. Semantic facilitation and orthographic inhibition arose only in the immediate priming task. Moreover, morphological effects were significantly greater than the sum of semantic and orthographic effects at a stimulus onset asynchrony of 300 ms but were not reliably different at shorter durations. The adequacy of an account that describes morphological relatedness as distinct from the composite effects of semantic and orthographic similarity must account for changes in additivity across prime durations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are hemispheric strategy differences independent of the level of performance?

Studies requiring identification of consonant-vowel-consonant (CVC) nonwords have suggested that attention is distributed more slowly or sequentially across the letters when they are presented to the right hemisphere than to the left hemisphere. Two experiments investigated whether hemispheric differences in processing strategy would be reduced with reductions of hemispheric differences in accuracy. The magnitude of visual field differences in accuracy was controlled by manipulating exposure duration, and the effect was observed on visual field differences in processing strategy. For both CVC identification (Experiment 1) and identification of nonletter symbols (Experiment 2), hemispheric strategy differences were independent of differences in accuracy. Both quantitative and qualitative hemispheric strategy differences in processing visual displays appear to depend on the nature of the stimuli and the nature of the processes they invoke. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reconceptualizing the work–family interface: An ecological perspective on the correlates of positive and negative spillover between work and family.

Ecological theory was used to develop a more expanded conceptualization of the work–family interface and to identify significant correlates of multiple dimensions of work–family spillover. Using data from employed adults participating in the National Survey of Midlife Development in the United States (N?=?1,986), negative spillover from work to family, positive spillover from work to family, negative spillover from family to work, and positive spillover from family to work were found to be distinct work–family experiences. Analyses indicated that work and family factors that facilitated development (e.g., decision latitude, family support) were associated with less negative and more positive spillover between work and family. By contrast, work and family barriers (e.g., job pressure, family disagreements) were associated with more negative spillover and less positive spillover between work and family. In some cases, results differ significantly by gender. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Can “good” stressors spark “bad” behaviors? The mediating role of emotions in links of challenge and hindrance stressors with citizenship and counterproductive behaviors.

The authors combined affective events theory (H. M. Weiss & Cropanzano, 1996) and the transactional stress model (R. S. Lazarus & Folkman, 1984) to build and test a model specifying the dynamic, emotion-based relationships among challenge and hindrance stressors and citizenship and counterproductive behaviors. The study employed an experience sampling methodology. Results showed that challenge stressors had offsetting indirect links with citizenship behaviors through attentiveness and anxiety and a positive indirect effect on counterproductive behaviors through anxiety. Hindrance stressors had a negative indirect effect on citizenship behaviors through anxiety and a positive indirect effect on counterproductive behaviors through anxiety and anger. Finally, multilevel moderating effects showed that the relationship between hindrance stressors and anger varied according to employees’ levels of neuroticism. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Do women's provider-role attitudes moderate the links between work and family?

The authors examined the links between mothers' work qualities and their individual well-being and marital quality, as well as adolescent daughters' and sons' gender-role attitudes, as a function of mothers' provider-role attitudes, in 134 dual-earner families. In home interviews, mothers described their work, provider-role attitudes, family relationships, and mental health; their offspring reported gender-role attitudes. Women's attitudes about breadwinning were coded into main-secondary, coprovider, and ambivalent coprovider groups. Mothers' provider-role attitudes moderated the links between status indicators and mothers' depression, marital conflict, and daughters' gender-role attitudes. For example, depression and marital conflict were negatively related to coprovider mothers' earnings and occupational prestige. The same was not true for main-secondary and ambivalent coprovider mothers. These findings underscore the importance of considering employed women's interpretation of their work roles when exploring work-family links. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are individual or consecutive letters the unit affected by repetition blindness?

When 2 similar words (e.g., react reach) are briefly sequentially displayed, the 2nd word may be omitted from the report, a phenomenon known as repetition blindness (RB). Previous researchers have suggested that consecutive letters are the unit affected by RB. Six experiments provided new data on orthographic RB. Two letters at the beginning or end of words resulted in RB, as did alternating interior letters (tactile earthly) and 3 letters with different relative positions (arid bird). However, no RB was found with a single final letter (show view). Observed RB may reflect pattern completion because RB for pairs like throat theory was reduced when the nonrepeated letters (eory) were consistent with only a single word. The experiments point to a model of orthographic RB in which both individual letters and letter sequences of length 2 or more play a role. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An investigation of the effects of time and involvement in the relationship between stressors and work–family conflict.

Previous researchers have proposed that the time and energy involved in family and paid work should affect the relationship between stressors and conflict in both the work and family domains. Using a sample of 113 registered nurses, the authors hypothesized that the amount of time and involvement in both domains would moderate the stressor–conflict relationships. Results supported many of the interactions in predicting conflict in each domain, and implications for the health of working women with family responsibilities were discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Is "involuntary childlessness" within the realm of family medicine responsibility of the general practitioner?

The aim of the study was to assess whether or not management of infertility is within the domain of the general practitioner in his capacity as a family physician. All accredited family physicians in the wider area of Goettingen were invited to take part in our survey. A total of 57 doctors (84%) participated. In personal interviews the family physicians were encouraged to frankly discuss the following main topics: the frequency of infertility in their own practice as well as their care for and attitudes towards infertile patients. Many family physicians interviewed were reluctant to address involuntary childlessness and underestimated its frequency. According to their patients' needs and demands, however, family doctors--above all in rural practices--have been participating in the screening and counseling of, and providing emotional support for, involuntarily childless patients. A qualitative analysis of the interview data revealed that many family physicians regarded infertility as the patients' private matter and placed it within the domain of specialists. About one-third of the physicians expressed negative attitudes towards infertile patients. Moreover, assisted reproduction techniques were sometimes rejected as "unnatural" methods. If a family-oriented approach should be amplified in family practice by offering supportive counseling for infertile patients, continuing medical education will have to take these attitudes into account.     

Why are some texts good and others not? Relationship between text quality and management of the writing processes.

Two experiments examined whether text quality is related to online management of the writing processes. Experiment 1 focused on the relationship between online management and text quality in narrative and argumentative texts. Experiment 2 investigated how this relationship might be affected by a goal emphasizing text quality. In both experiments, psychology students were instructed to think aloud while composing their texts. Reaction times to auditory probes were also collected to reflect writers' cognitive effort. Two sets of variables were measured: general temporal indicators (fluency, prewriting pause) and online management of writing processes (number, mean length of episodes). Finally, text quality was assessed. As expected, results confirmed that narrative and argumentative texts are composed using different strategies. Students also composed better texts when a quality-based goal had been set. The main reliable indicator of text quality was an increase of the prewriting pause and of planning processes. These findings indicate that writers tailor their writing behavior to match the type and quality of the text they are asked to produce. These results are discussed in the light of interventions and recommendations in the classroom. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Insomnia and the eye of the beholder: Are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints?

Previous findings suggest that some who report insomnia sleep well, whereas some noncomplaining individuals sleep rather poorly. This study was conducted to determine if mood, anxiety, and sleep-related beliefs might relate to perceived sleep disturbance. Thirty-two women and 32 men (aged 40–79 years) with primary insomnia and an aged-matched sample of 61 normal sleepers (31 women, 30 men) completed 6 nocturnal sleep recordings, as well as the Beck Depression Inventory (BDI), the Trait portion of the State-Trait Anxiety Inventory (STAI-2), and the Dysfunctional Beliefs and Attitudes About Sleep Questionnaire. Sleep and interview data were used to subdivide the majority of the sample (n?=?108) into objective normal sleepers and subjective insomnia sufferers who seemingly slept well and subjective normal sleepers and objective insomnia sufferers who slept poorly. The 2 subjective subgroups showed the most marked differences on most of the psychometric measures. The findings suggest that the psychological factors scrutinized in this study may mediate sleep satisfaction and/or predict objective sleep difficulties. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are adolescents less mature than adults?: Minors' access to abortion, the juvenile death penalty, and the alleged APA "flip-flop."

The American Psychological Association’s (APA’s) stance on the psychological maturity of adolescents has been criticized as inconsistent. In its Supreme Court amicus brief in Roper v. Simmons (2005), which abolished the juvenile death penalty, APA described adolescents as developmentally immature. In its amicus brief in Hodgson v. Minnesota (1990), however, which upheld adolescents’ right to seek an abortion without parental involvement, APA argued that adolescents are as mature as adults. The authors present evidence that adolescents demonstrate adult levels of cognitive capability earlier than they evince emotional and social maturity. On the basis of this research, the authors argue that it is entirely reasonable to assert that adolescents possess the necessary skills to make an informed choice about terminating a pregnancy but are nevertheless less mature than adults in ways that mitigate criminal responsibility. The notion that a single line can be drawn between adolescence and adulthood for different purposes under the law is at odds with developmental science. Drawing age boundaries on the basis of developmental research cannot be done sensibly without a careful and nuanced consideration of the particular demands placed on the individual for “adult-like” maturity in different domains of functioning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are the salutogenic effects of social supports modified by income? A test of an "added value hypothesis".

Older adults (54 men, 113 women; M age?=?69.5 years) were examined to test the hypothesis that social supports would be more salutogenic (health promoting) for persons with lower incomes than for persons with higher incomes. Interactions of income and social supports (mean of 3 emotional scales of the Interpersonal Support Evaluation List) at study entry predicted changes 15–18 months later in a cardiovascular composite (linear combination of high-density lipoproteins-mean arterial pressure; p?p?$29,000/year). In contrast, interactions of the Tangible Support Scale with income did not occur. Persons with lower incomes may derive benefits from social supports that go beyond tangible assistance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Too engaged? A conservation of resources view of the relationship between work engagement and work interference with family.

In a number of studies, researchers interested in positive organizational behavior have sought to better understand the favorable aspects of work engagement—a pervasive state of emotional attachment and motivation toward work. In this study, however, we investigate a potentially negative outcome of engagement. Drawing upon conservation of resources theory, we hypothesize that engagement will be associated with higher work interference with family due to the resources engaged employees may expend when they engage in extrarole work behavior such as organizational citizenship behaviors (OCBs). We further propose that conscientiousness, as a personal resource, serves to buffer the relationship between OCB and work interference with family. Examining multisource data, collected at multiple points in time, from 3 diverse samples (total N = 844), we find that state engagement is associated with higher levels of work interference with family and that this relationship is mediated by the performance of OCBs. The findings also indicate that engaged employees who are highly conscientious experience lower levels of work interference with family than engaged employees who are less conscientious. The implications of our study and directions for future research are also discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are our publications and conventions suitable for the personal sciences?

What is there about intellectual meetings and scientific journals that makes certain kinds of truths or types of expressions of truth not "suitable" or appropriate? We are groping in the memorial meeting toward the phenomenological, the experiential, the existential, the ideographic, the unconscious, the private, the acutely personal; and yet we are trying to do this in an inherited intellectual atmosphere or framework which is quite unsuitable and unsympathetic, one which I might even call forbidding. Our journals, books, and conferences, I have discovered, are primarily suitable for the communication and discussion of the rational, the abstract, the logical, the public, the impersonal, the nomothetic, the repeatable, the objective, the unemotional. We keep trying to use the canons and folkways of impersonal science for our personal science, and it is quite clear to me that it will not work. We must make explicit what we all accept implicitly: that our kind of work is felt deeply and comes out of deep personal grounds, that we fuse with the objects of study rather than splitting from them, that we are profoundly involved, and that, we must be if our work is not to be a fakery and a phoniness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Are cultural characteristics associated with the relationship between self and others’ ratings of leadership?

This study examined the relationship between self and subordinate ratings of leadership and the relationship between self and peer ratings of leadership for 964 managers from 21 countries. Using multilevel modeling, the authors found that cultural characteristics moderated the relationship between self and others’ ratings of leadership. Specifically, the relationship between self and subordinate ratings, as well as between self and peer ratings, was more positive in countries that are characterized by high assertiveness. The relationship between self and subordinate ratings, as well as between self and peer ratings, was also more positive in countries characterized by high power distance. The authors also found a leniency bias in individualistic cultures for self, peer, and subordinate ratings. In sum, cultural characteristics should be considered in attempts to understand relationships between self and other ratings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)