Mammographic mass detection by adaptive thresholding and region growing

We present an efficient method to detect mass lesions on digitized mammograms, which consists of breast region extraction, region partitioning, automatic seed selection, segmentation by region growing, feature extraction, and neural network classification. The method partitions the breast region into a fat region, a fatty and glandular region, and a dense region, so that different threshold values can be applied to each partitioned region during processes of the seed selection and segmentation. The mammographic masses are classified by using four features representing shape, density, and margin of the segmented regions. The method detects subtle mass lesions with various contrast ranges and can facilitate a procedure of mass detection in computer‐aided diagnosis systems. © 2001 John Wiley & Sons, Inc. Int J Imaging Syst Technol, 11, 340–346, 2000     

Detection of brain tumour from MRI image using modified region growing and neural network

Abstract

Region growing is an important application of image segmentation in medical research for detection of tumour. In this paper, we propose an effective modified region growing technique for detection of brain tumour. It consists of four steps which includes: (i) pre-processing; (2) modified region growing by the inclusion of an additional orientation constraint in addition to the normal intensity constrain; (3) feature extraction of the region; and (4) final classification using the neural network. The performance of the proposed technique is systematically evaluated using the magnetic resonance imaging (MRI) brain images received from the public sources. For validating the effectiveness of the modified region growing, we have considered the quantity rate parameter. For the evaluation of the proposed technique of tumour detection, we make use of sensitivity, specificity and accuracy values which we compute from finding out false positive, false negative, true positive and true negative. Comparative analyses were made of the normal and the modified region growing using both the Feed Forward Neural Network (FFNN) and Radial Basis Function (RBF) neural network. From the results obtained, we could see that the proposed technique achieved the accuracy of 80% for the testing dataset, which clearly demonstrated the effectiveness of the modified region growing when compared to the normal technique.     

Breast cancer diagnosis from mammographic images using optimized feature selection and neural network architecture

Breast cancer is one of the deadly diseases in women that have raised the mortality rate of women. An accurate and early detection of breast cancer using mammogram images is still a complex task. Hence, this article proposes a novel breast cancer detection model, which included five major phases: (a) preprocessing, (b) segmentation, (c) feature extraction, (d) feature selection, and (e) classification. The input mammogram image is initially preprocessed using contrast limited adaptive histogram equalization (CLAHE) and median filtering. The preprocessed image is then subjected to segmentation via the region growing algorithm. Subsequently, geometric features, texture features and gradient features are extracted from the segmented image. Since the length of the feature vector is large, it is essential to select the optimal features. Here, the selection of optimal features is done by a hybrid optimization algorithm. Once the optimal features are selected, they are subjected to the classification process involving the neural network (NN) classifier. As a novelty, the weight of NN is selected optimally to enhance the accuracy of diagnosis (benign and malignant). The optimal feature selection as well as the weight optimization of NN is accomplished by merging the Lion algorithm (LA) and particle swarm optimization (PSO), named as velocity updated lion algorithm (VU‐LA). Finally, a performance‐based evaluation is carried out between VU‐LA and the existing models like, whale optimization algorithm (WOA), gray wolf optimization (GWO), firefly (FF), PSO, and LA.     

A novel hybrid artificial neural network technique for the early skin cancer diagnosis using color space conversions of original images

In this study, an innovative hybrid machine learning-technique is used for the early skin cancer diagnosis fusing Convolutional Neural Network and Multilayer Perceptron to analyze images and information related to the skin cancer. This information is extracted manually after applying different color space conversions on the original images for better screening of the lesions. The proposed architecture is compared with standalone architecture in addition to some other techniques by commonly used evaluation metrics. HAM10000 dataset is used for training and testing as this data contain seven different skin lesions. The novelty of the proposed hybrid model is the structure of the network which handles structured data (patients' metadata and other useful features from different color spaces related to the illumination, energy, darkness, etc.) and unstructured data (images). The results show an overall 86%, 95% top-1 and top-2 accuracy respectively, and 96% area under the curve for the seven classes. The study demonstrates the superiority of the proposed hybrid model with a 2% improvement in the accuracy over the standalone model and a promising behavior as compared to the ensemble techniques. The follow-up research will include more patient data to develop a skin cancer detection device.     

Automatic breast cancer detection based on optimized neural network using whale optimization algorithm

Breast cancer is the second deadliest type of cancer. Early detection of breast cancer can considerably improve the effectiveness of treatment. A significant early sign of breast cancer is the mass. However, separating the cancerous masses from the normal portions of the breast tissue is usually a challenge for radiologists. Recently, because of the availability of high‐accuracy computing, computer‐aided detection systems based on image processing have become capable of accurately diagnosing the various types of cancers. The main purpose of this study is to utilize a powerful image segmentation method for the diagnosis of cancerous regions through mammography, based on a new configuration of the multilayer perceptron (MLP) neural network. The most popular method for minimizing the errors in an MLP neural network is backpropagation. However, this method has certain drawbacks, such as a low convergence speed and becoming trapped at the local minimum. In this study, a new training algorithm based on the whale optimization algorithm is proposed for the MLP network. This algorithm is capable of solving various problems toward the current algorithms for the analyzed systems. The proposed method is validated on the Mammographic Image Analysis Society database, which contains 322 digitized mammography images, and the Digital Database for Screening Mammography, which contains approximately 2500 digitized mammography images. To assess the detection performance of the proposed system, the correct detection rate, percentage of identification with false acceptance, and percentage of identification with false rejection were evaluated and compared using various methods. The results indicate that the proposed method is highly efficient and yields significantly better accuracy compared with other methods.     

Deep learning and optimization algorithms for automatic breast cancer detection

Breast cancer is caused by the abnormal and rapid growth of breast cells. An early diagnosis can ensure an easier and effective treatment. A mass in the breast is a significant early sign of breast cancer, even though differentiating the cancerous mass's tissue from normal tissue for diagnosis is a difficult task for radiologists. The development of computer-aided detection systems in recent years has led to nondestructive and efficient cancer diagnostic techniques. This paper proposes a comprehensive method to locate the cancerous region in the mammogram image. This method employs image noise reduction, optimal image segmentation based on the convolutional neural network, a grasshopper optimization algorithm, and optimized feature extraction and feature selection based on the grasshopper optimization algorithm, thereby improving precision and decreasing the computational cost. This method was applied to the Mammographic Image Analysis Society Digital Mammogram Database and Digital Database for Screening Mammography breast cancer databases and the simulation results were compared with 10 different state-of-the-art methods to analyze the proposed system's efficiency. Final results showed that the proposed method had 96% Sensitivity, 93% Specificity, 85% PPV, 97% NPV, 92% accuracy, and better efficiency than other traditional methods in terms of Sensitivity, Specificity, PPV, NPV, and Accuracy.