海藻酸-羧甲基葡甘聚糖共混膜的结构与性能研究

对魔芋葡甘聚糖进行羧甲基化改性,制得醚化度为0.54的羧甲基葡甘聚糖。再利用溶液共混法制备海藻酸钠-羧甲基葡甘聚糖共混膜,通过红外光谱、X-射线衍射、原子吸收光谱和扫描电镜对共混膜的结构进行了表征;并测定了不同配比共混膜的拉伸强度、断裂伸长率,吸水率和水蒸汽透过率,同时考察了NaCl浓度对共混膜吸水率的影响。结果表明:共混膜中海藻酸和羧甲基葡甘聚糖间具有较强的相互作用,良好的相容性。共混膜具有良好的力学性能,在生物材料领域有潜在利用价值。     

魔芋葡甘聚糖基敷料的研究及其应用进展

魔芋葡甘聚糖因具有良好的生物相容性、吸水性及凝胶性而被广泛应用于医用敷料领域，且魔芋葡甘聚糖含量丰富，又可生物降解，以魔芋葡甘聚糖为基底的医用敷料的部分性能较传统类型敷料有其独特优势，同时通过物理和化学等改性，可以研究出各种性能不同的新型敷料。本文总结了魔芋葡甘聚糖的近年来的研究，和其在敷料领域的应用。最后对魔芋葡甘聚糖敷料的发展做出展望。     

魔芋葡甘聚糖溶胶流变特性及应用研究进展

主要综述了魔芋葡甘聚糖和改性魔芋葡甘聚糖溶胶流变特性．以及各种改性方法对其溶胶流变特性的影响．魔芋葡甘聚糖流变特性的多样性．未改性的魔葡甘聚糖是极为典型的假塑性流体．而改性后的魔芋葡甘聚糖开始呈现出较为明显的牛顿流体行为,且其流变特性受诸多因素的影响．葡甘聚糖经改性后．其透明度、粘度、冻融稳定性均明显改善。此外还总结了魔芋葡甘聚糖溶胶的应用。     

魔芋葡甘聚糖及其衍生物的应用研究进展

综述了魔芋葡甘聚糖及其衍生物在食品、医药、环保等领域的应用。     

魔芋精粉中葡甘聚糖含量的测定

魔芋中的葡甘聚糖是一种可再生的天然高分子资源,具有流变性、水溶性和凝胶性等理化性质。目前魔芋葡甘聚糖的应用主要是在食品、化工和医疗等行业。能够简单快捷测定魔芋精粉中葡甘聚糖含量具有重要意义,本论文采用分光光度法快速测定魔芋中的葡甘聚糖含量。     

交联魔芋葡甘聚糖水凝胶包裹尿素的缓释效果

以魔芋粉为原料，经三级醇溶去杂工艺，得纯化魔芋葡甘聚糖；以环氧氯丙烷为交联剂，制备出交联魔芋葡甘聚糖水凝胶；交联魔芋葡甘聚糖水凝胶于尿素水溶液中强力搅拌，抽滤，制得包裹尿素的交联魔芋葡甘聚糖水凝胶。试验了交联魔芋葡甘聚糖水凝胶对尿素的包裹率；以及包裹尿素的交联魔芋葡甘聚糖水凝胶缓释尿素的效果。结果表明，交联魔芋葡甘聚糖水凝胶对尿素缓释效果良好。     

魔芋葡甘聚糖在食品、生物、医学及化工领域的应用

魔芋葡甘聚糖(Konjac Glucomannan,简称KGM)作为一种天然高分子,是我国特产资源。KGM具有和纤维素类似的结构,但却具有纤维素所不具备的水溶解性。KGM分子中含有丰富的羟基及可修饰乙酰基团。对魔芋葡甘聚糖在食品、生物、医学及化工领域的应用进行综述,提出了存在问题并展望了其应用前景。     

大豆蛋白负载魔芋葡甘聚糖对Cd(Ⅱ)的吸附性能

镉污染引发的环境和食品安全问题严重威胁人类的身体健康。本文将大豆蛋白负载于魔芋葡甘聚糖凝胶分子骨架上,通过化学交联后,获得结构稳定的大豆蛋白负载魔芋葡甘聚糖吸附材料,并对其结构进行详细的表征,进一步研究其对Cd(Ⅱ)的吸附性能。 结果表明,大豆蛋白负载魔芋葡甘聚糖吸附材料具有疏松多孔结构,对Cd(Ⅱ)的吸附速率极快,能在5min内达到吸附平衡,吸附符合准二级反应动力学。大豆蛋白负载魔芋葡甘聚糖对Cd(Ⅱ)脱除效率较高,能达到99.99%。等温吸附结果表明,大豆蛋白负载魔芋葡甘聚糖对Cd(Ⅱ)的吸附符合Langmuir等温吸附方程,最大吸附容量可达52.63mg/g。     

魔芋葡甘聚糖材料疏水改性的研究进展

介绍了魔芋葡甘聚糖与高分子材料共混疏水改性的方法,评述了化学改性中魔芋葡甘聚糖脱乙酰基化、交联、接枝共聚、互穿聚合物网络、羧甲基化等疏水改性的最新研究进展,探讨了其今后的研究方向,并提出了开发热塑性KGM材料这一前沿性课题。     

魔芋葡甘聚糖膜的制备及其血液相容性研究

制备了魔芋葡甘聚糖膜,并通过复钙实验、溶血实验、凝血实验研究了其血液相容性。结果表明,魔芋葡甘聚糖膜的溶血度低于5％、内源性凝血因子被激活的程度低,表明其具有较好的血液相容性,应用潜力很大。魔芋葡甘聚糖膜的复钙时间短于纯血浆,但仍需进一步深入研究。     

The effects of graphene oxide on the properties and drug delivery of konjac glucomannan hydrogel

Konjac glucomannan (KGM) hydrogel has good potential application in food and medical science, although to achieve this, the physical and mechanical properties need further improvement. In this study, graphene oxide (GO) was used to improve the functionality of KGM hydrogel. KGM/GO hydrogels were prepared by freezing the alkaline KGM/GO sols. Rotational rheometer was used to study the rheological properties of different alkaline KGM/GO sols. Fourier transform infrared, Raman, differential scanning calorimetry, thermogravimetric analyses, and scanning electron microscopy were used to evaluate the structure and properties of the hydrogels. In addition, different pH solutions and an in vitro assay were used to study the swelling property and the release behavior of KGM/GO hydrogels, respectively. The result revealed strong hydrogen‐bond interaction between KGM and GO. The incorporation of GO highly improved the gel properties of KGM/GO sol, higher thermal stability, and more compact structure of KGM/GO hydrogels. KGM/GO hydrogels showed better swelling properties in deionized‐distilled water and pH 7.2 PBS. The release of 5‐aminosalicylic acid (5‐ASA) from KGM/GO (KG4) hydrogel was different in various pH media, but the initial burst release effect was very severe. Therefore, incorporation of GO have a good potential in enhancing the properties of KGM hydrogel, but KGM/GO hydrogel is not an ideal carrier for 5‐ASA release. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134, 45327.     

不同分子量魔芋葡甘聚糖与聚丙烯酸互穿网络凝胶作为药物载体的制备与表征

对不同分子量的魔芋葡甘聚糖(重均分子量分别为1.070×106,8.272×105,7.329×105和6.012×105)与丙烯酸在引发剂(K2S2O8)和交联剂(MBAAm)的作用下形成的互穿网络(KGM/PAA-IPN)作为缓释药物载体的性能进行了研究。通过红外、扫描电镜、溶胀率、生物降解性和体外释放等对凝胶进行表征。溶胀分析表明KGM/PAA-IPN在pH值7.4时的溶胀率明显大于pH值2.2时的溶胀率,且由分子量较大的KGM组成的KGM/PAA-IPN凝胶的溶胀率、失重速度和失重率都明显大于由分子量较小的KGM组成的KGM/PAA-IPN凝胶。因此,KGM/PAA-IPN凝胶作为药物载体具有生物降解性和pH敏感性,且适当降低KGM的分子量有利于KGM/PAA-IPN凝胶在药物缓释过程中的稳定性。     

Konjac Glucomannan/Poly(vinyl alcohol)/Na+Rectorite Nanocomposite Films: Structure, Characteristic and Drug Delivery Behaviour

Konjac glucomannan(KGM)/poly(vinyl alcohol)(PVA)/Na⁺ modified rectorite (Na⁺REC) nanocomposite films were obtained by using a casting/solvent evaporation method. The structures and microstructures of KGM/PVA/Na⁺REC composite films were analyzed by FTIR, XRD, SEM and TEM. A wide variety of material characteristics for the KGM/PVA/Na⁺REC composite films were investigated, including the mechanical property, optical transmittance and thermal stability. The results revealed that by adding PVA more well-intercalative/exfoliated structure of composite film was obtained. As a result, the KGM/PVA/Na⁺REC composite film at low Na⁺REC and PVA content exhibited an improvement in mechanical properties and thermal stability due to a reinforcement effect. In vitro drug-controlled release studies showed a slower and more continuous release for KGM/PVA/Na⁺REC composite film in comparison with KGM/Na⁺REC composite film.     

魔芋葡甘聚糖/凹凸棒石纳米复合材料的制备及性能

以江苏盱眙提纯凹凸棒石（attapulgite,AT）为原料,以魔芋葡甘聚糖（konjac glucmannan,KGM）为基体,采用共混法制备了KGM/AT纳米复合材料,探讨了凹凸棒石质量分数、KGM质量分数对纳米复合材料性能的影响。力学性能测试结果表明：当魔芋用量为0.50%、凹凸棒石用量为0.02%时,复合材料的综合力学性能最好,与纯魔芋膜相比,其拉伸强度、断裂伸长率和弹性模量分别提高54.95%、19.97%、10.79%。利用Fourier红外光谱、扫描电子显微镜对纳米复合材料进行了表征,结果表明：AT的引入,KGM分子某些特征峰的波数发生了明显变化,凹凸棒石与魔芋葡甘聚糖发生了强烈的相互作用形成了新的界面层,且AT在纳米复合材料中分散性较好。     

A novel membrane on pervaporation performance for dehydration of Caprolactam solution

Konjac glucomannan (KGM) is a kind of polysaccharide with wide applications, except in pervaporation (PV). This article focuses on the new function of KGM and simultaneously improving a new dehydration process for ?-Caprolactam (CPL). KGM was cross-linked with glutaraldehyde (GA) at proportions of 0.3, 0.5, and 0.7 wt%. Cross-linked membranes were characterized by scanning electron microscope, Fourier transform-infrared, and X-ray diffraction to assess the membranes of morphology, intermolecular interactions, and observe the effects of cross-linking on crystallinity, respectively. Cross-linked KGM as the active layer of the composite membranes has the net matrix structure, and many characteristics improved compared with pure KGM. Data showed that KGM cross-linked with GA displayed good swelling and PV performance, and the composite membranes had superior separation performances in dehydrating the CPL solution. The highest separation factor could reach 3531. The study provided a new way for both KGM application and CPL dehydration.     

Synthesis and characterization of konjac glucomannan/poly(vinyl alcohol) interpenetrating polymer networks

Novel interpenetrating polymer networks (IPNs) coded as KP were synthesized successfully from poly(vinyl alcohol) (PVA) and konjac glucomannan (KGM) in the presence of glutaraldehyde as a crosslink agent. The transparent IPN films that were 40 μm thick were prepared by means of conventional solvent‐casting technique and dried at room temperature for 2 days. The structure and miscibility of the KP films were studied by Fourier transformed infrared spectra, scanning electron microscopy, differential scanning calorimetry, wide‐angle X‐ray diffraction, and ultraviolet visible spectroscopy (UV–Vis). The results indicated that strong intermolecular interaction caused by crosslink bonding between PVA and KGM occurred in the IPN films, resulting in wonderful miscibility when the reaction time is 4 h. The tensile strength, elongation at break, and moisture uptake was much higher than that of the pure PVA film, KGM film, and uncrosslinked blend films. In other words, the structure of IPN endowed the films with excellent performance, so the new material has promising applications to food package film and agricultural film because of its biodegradability. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 2775–2780, 2004     

改性魔芋葡甘聚糖纳米晶对聚乙烯醇薄膜性能的影响

通过硫酸水解魔芋葡甘聚糖(KGM)得到魔芋葡甘聚糖纳米晶(NKGM),再表面接枝3-(三甲氧基硅丙基)十八烷基氯化铵,与壬基酚聚氧乙烯醚硫酸钠反应等过程得到改性KGM纳米晶类流体(NKGMf);然后采用溶液流延法制备了含NKGM和NKGMf的聚乙烯醇(PVA)薄膜;通过傅里叶变换红外光谱仪、透射电子显微镜、扫描电子显微镜、热失重分析仪、拉伸测试仪等对NKGM、NKGMf的结构和PVA薄膜的性能进行表征。结果表明,经改性后,NKGM的片状结构得以保留,在PVA基质中的分散性增加,薄膜的起始分解温度提高了23℃,拉伸强度提高了34.7%,其中,NKGMf的最佳含量为3%(质量分数,下同)。     

Study on properties and aggregation structures of deacetylated konjac glucomannan/chitosan hydrochloride absorbent blend gel films

A series of novel blend films of deacetylated konjac glucomannan (d‐KGM) and Chitosan hydrochloride (CHI·HCl) were prepared successfully by using the solvent‐casting technique with different blending ratios of the two polymers. The miscibility and aggregation structure of the blend films were studied by Fourier transform infrared spectroscopy, wide‐angle X‐ray diffraction and scanning electron microscopy. The results indicated that the blend system of d‐KGM and CHI·HCl had a conditional miscibility. A new crystal occurred and hydrogen‐bonding interaction was strengthened when the CHI·HCl content in the blend films was 40%. The effects of deacetylation degree of KGM, acids (the solvent Chitosan dissolved in), temperature, and the mix ratio on the swelling behavior of the blend films were also studied. The blend film KC3 (CHI·HCl content in the blend films was 30%) had not only the highest equilibrium swelling degree (26 times) but also the highest tensile strength, and it could be regarded as a potential absorbent film material. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010     

旋转膜乳化法制备均一魔芋葡苷聚糖凝胶微球

以天然多糖魔芋葡苷聚糖(KGM)为材料,采用旋转膜乳化法结合化学交联法制备均一的魔芋葡苷聚糖凝胶微球,以3种不同粘度的12%(w) KGM水溶液为分散相(水相)、液体石蜡(LP):石油醚(PE)混合油相为连续相,考察了乳化剂种类对KGM乳液稳定性的影响及水相粘度、油相配比和膜管转速对KGM成球的影响. 结果表明,KGM水相粘度越高,相应的最佳油相粘度越低,最佳KGM水相粘度为1548 mPa×s,最佳油相体积比为LP:PE=5:1,最优膜管转速为400 r/min,利于KGM乳液稳定的乳化剂是4%(w) Span 80. 该条件下制得粒径约70 μm、粒径分布系数Span<1.0的均一KGM微球.