In vivo evaluation of a new composite mesh (10% polypropylene/90% poly-<Emphasis Type="SmallCaps">l</Emphasis>-lactic acid) for hernia repair

The increasing use of mesh insertion for groin hernia repair is dashed by a worrying prevalence of chronic pain frequently related as a reaction to the biomaterial implantation. Thus, new biocompatible prosthesis, designed as a composite material associating polypropylene (PP) and long-term absorbable material, are now under development. In the present study, the typical commercially available Prolene mesh has been compared to two new meshes designed with 3-fold less PP, either alone (light PP) or associated with poly-L-lactic acid (PP-PLA) accounting for 90% of the mesh weight. These PP-mesh variants were implanted in an extraperitoneal position within the abdominal wall of 90 rats. Mesh adhesion and size were determined at autopsy 2, 4 and 8 weeks after implantation (10 animals per group) and morphometric parameters of the host tissues by light microscopy. Prolene and light PP-meshes presented intra-corporeal shrinkage and tissue adhesion, both more pronounced with light-PP, whilst PP-PLA meshes were not affected in spite of a strongest fibrosis. In contrast to Prolene and even more with light PP meshes, inflammation and cell-mediated immune responses were reduced without occurrence of angiogenesis or oedema. All these findings advocate together for a better tolerance of this new composite biomaterial, more likely due to a low macrophage response that appeared statistically correlated to the absence of mesh shrinkage and to a decreased adhesion to the tissue. On the basis of these experimental observations, it could be expected that the better tolerance of this composite biomaterial may avoid both long-term pain and recurrence when used as plug in groin hernia repair.     

<Emphasis Type="Italic">p</Emphasis>-AgCoO<Subscript>2</Subscript>/<Emphasis Type="Italic">n</Emphasis>-ZnO heterojunction diode grown by rf magnetron sputtering

P-type transparent semiconducting AgCoO₂ thin films were deposited by rf magnetron sputtering of sintered AgCoO₂ target. The AgCoO₂ films grown by rf sputtering were highly c-axis oriented showing only (001) reflections in the X-ray diffraction pattern unlike in the case of amorphous films grown by pulsed laser deposition (PLD). The bulk powder of AgCoO₂ was synthesized by hydrothermal process. The optical bandgap was estimated as 4·15 eV and has a transmission of about 50% in the visible region. The temperature dependence of conductivity shows a semiconducting behaviour. The positive sign of Seebeck coefficient (+220 μVK⁻¹) indicates p-type conductivity. Transparent p-n heterojunction on glass substrate was fabricated by rf magnetron sputtering of p-AgCoO₂ and n-type ZnO: Al thin films. The structure of the diode was glass/ITO/n-ZnO/p-AgCoO₂. The junction between p-AgCoO₂ and n-ZnO was found to be rectifying.     

Personal computer-basedcamac system for data acquisition

A single board auxiliarycamac crate controller for a Z80-A based personal computer ZX-spectrum to drive thecamac crate housing multipleadc, tdc, dac and 16 I/O ports has been developed. Thecamac crate controller used in this system is of A2 type which supports multiple auxiliary crate controllers. Acamac exerciser/training software for the use ofcamac commands in process control as well as data acquisition has been developed.     

Thermal properties of some α-amino acids in aqueous solutions

The thermal properties (thermal conductivity, thermal diffusivity, and volumetric heat capacity) of aqueous solutions of -amino acids [R-CH(NH₂)COOH]—glycine, dl-alanine, l-valine, and dl-leucine, were measured in the temperature range 20–90C using the hot-wire technique. The results show that the values of the thermal properties depend mainly on the amino acid concentration in the medium, the substituted alkyl group of the substances under investigation, and the temperatures. The mechanism of heat transfer is discussed, and the roles of both radiation and convection are taken into consideration.     

Parametric study of the electrical to thermal power conversion in an inductively coupledrf plasma torch

An inductively coupled (ic) radio-frequency (rf) stabilized argon plasma was generated in a quartz tube using a 7 MHzrf generator. The electrical and thermal powers were measured and the efficiency of energy conversion was computed. The results indicate that for a constant power input, there is an optimum argon flow rate for which maximum energy conversion efficiency occurs.     

<Emphasis Type="Italic">T</Emphasis><Subscript><Emphasis Type="Italic">z</Emphasis></Subscript> constraints of semi-elliptical surface cracks in elastic plates subjected to uniform tension loading

The out-of-plane constraints T_z around the semi-elliptical surface cracks in an elastic plate subjected to uniform tension loading have been investigated through detailed three-dimensional (3D) finite element (FE) analyses. The distributions of T_z are obtained in the vicinity of the crack border with aspect ratios of 0.2, 0.4, 0.5, 0.6, 0.8 and 1.0. T_z drops from Poissons ratio at the crack tip to approximate zero beyond certain radial distance in the normal plane of the crack front line, and increases gradually from the free surface to the mid-plane at the same radial distance. By fitting the numerical results, empirical formulae are obtained to describe the 3D distributions of T_z for semi-elliptical surface cracks with a sufficient accuracy in the wide aspect ratio range of 0.2a/c 1.0 except very near the free surface, where T_z is extremely low. T_z, combining with the corresponding K and T or J and Q, can be applied to establish the three-parameter dominated stress field, which can characterize the 3D crack front field completely as an attempt.     

Performance ofesprit in the presence of gain and phase mismatches in sensor doublets

esprit, an acronym for Estimation of Signal Parameters via Rotational Invariance Technique, is a novel method for estimating the Directions of Arrival (doa) of plane waves using an arbitrary array of sensor doublets. However,esprit requires an identical pair of sensors in each doublet, that is the gain and phase characteristics of the sensors in a doublet have to be matched, which may be difficult to ensure in practical situations. In this paper, assuming the sources to be uncorrelated, we analyse the performance ofesprit when the gain and phase characteristics of the sensors in a doublet are not identical. It is shown that the angle estimates are unbiased and expressions are derived for the variance in the estimates ofdoa, when gain and phase mismatches exist in doublets. Computer simulation results are also presented to assert the theoretical predictions.     

Antibody-based Detection of <Emphasis Type="Italic">Escherichia coli</Emphasis> O157:H7 and <Emphasis Type="Italic">Salmonella enterica</Emphasis> Serovar Typhimurium Grown in Low-shear Modeled Microgravity

With the advent of prolonged spaceflights, it is important to determine if antibody-based assays can be used to monitor food and water for bacterial contaminants. In the present work, a ground-based high aspect ratio vessel (HARV) was used to determine if low shear modeled microgravity (LSMMG) alters antibody-binding to E. coli O157:H7 and Salmonella enterica serovar Typhimurium. Antibody–bacteria binding was similar under LSMMG and normal gravity because there was no difference in amount of captured bacteria measured by colony forming units (CFU) between assays conducted in the HARV and a conventional roller flask. The ability of E. coli O157:H7 and Salmonella Typhimurium grown in LSMMG to bind specific antibodies was also studied. After incubations of 4, 18 or 36 h in the HARV or a shaking incubator, bacteria were harvested for enzyme-linked immunosorbent assays (ELISA). In the E. coli O157:H7 ELISA using a goat polyclonal primary antibody, LSMMG did not alter the linear range of detection (10⁵–10⁷ cells/ml) nor the signal to noise ratio at any bacterial concentration. Although insignificant changes in signal to noise ratios were evident, LSMMG did not alter the range of detection (10⁵–10⁷ cells/ml) for Salmonella Typhimurium in ELISAs using either a polyclonal or a monoclonal antibody. These results suggest that immunoassays may be used in spacecrafts because LSMMG does not have significant deleterious effects on antibody-binding to bacteria nor does it significantly alter surface antigens necessary for antibody-based methods.     

Integrated optoelectronics for optical interconnections and optical processing

Integrated optoelectronics using III–V compound semiconductor technology has so far shown exciting advances for application in optical telecommunication systems. New applications of this technology are in optical interconnections and signal processing systems. The technology is expected to be very effective in solving the wiring limit in data transmission within electronic systems, using the advantages of optical techniques such as high data transmission rate and high parallelism, and thus improve the performance of overall systems. Optical interconnection devices currently being developed aim both at multiplexing vast amounts of data and exhibiting flexible interconnection functions using the advantageous characteristics of light. Future research is expected to explore new techniques such as that for multiplexing and processing data in the wavelength division as well as for integrating functional devices in two-dimensions. Synergetic collaboration among materials and processing, design and fabrication, and packaging areas is extremely important and this will lead to practical optical interconnections and signal processing systems.     

Elastic properties of As-Sb-Se glasses

Results of measurement of elastic modulii on As-Sb-Se glasses are reported and their composition dependence discussed. The Young’s and the shear modulii lie in the range of 170–210 and 65–80 kb respectively. These values are typical of chalcogenide glasses. For (As, Sb)₄₀Se₆₀ glasses, the modulii increase monotonically with increasing Sb₂Se₃ content. The observed composition dependence of the modulii for the As _x Sb₁₅Se_{85 −x} glasses is examined in terms of the chemically ordered structural units in the glasses.     

Influence of specimen geometry and size-effect on the <Emphasis Type="Italic">K</Emphasis><Subscript><Emphasis Type="Italic">R</Emphasis></Subscript>-curve based on the cohesive stress in concrete

Comparative study for determining the K _R -curves associated with the cohesive stress distribution for complete fracture process for two standard specimen geometries i.e., three-point bending test and compact tension test specimen geometries of concrete using analytical method and weight function approach is reported in the paper. The laboratory size specimen (100 ≤  D  ≤  400 mm) with initial-notch length/depth ratios 0.3 and 0.5 are considered in the investigation. The load-crack opening displacement curves for these specimens are obtained using well known version of Fictitious Crack Model (FCM). It is found from the numerical results that the weight function method improves computational efficiency without any appreciable error. The stability analysis on the K _R -curves and the influence of specimen geometry and the size-effect on the K _R -curves, the CTOD-curves and the process zone length during crack propagation of complete fracture process are also described.     

Study of a complex water resources system with screening and simulation models

The study describes a sequential iterative modelling process for a complex water resource system. Two types of analytical models are used to find a reasonably small set of possible systems optimal design alternatives for a complex river basin. These models are a linear programming deterministic continuous (lpdc) model and a linear programing deterministic discontinous (lpdd) model. Linear programing has been used with linear approximation of the nonlinear functions. A simulation program has been developed which continues screening on the basis of the information obtained from the linear programing model. The models are developed in the context of analysis of the Narmada river, a large river basin in India, for which in the first instance alternative combinations and capacities of six major dams have to be decided.     

Thetranair rectangular grid approach to solving the nonlinear full-potential equation about complex configurations

This paper describestranair, a numerical method that uses a rectangular grid to solve the nonlinear full-potential equation about general complex configurations. The grid is locally refined to resolve the high velocity gradients arising from leading edge expansions or shock waves. The grid penetrates the boundary (described by networks of quadrilateral panels) and is generated automatically. Discrete operators are constructed using the finite element method. The system of nonlinear discrete equations is solved iteratively using an orthogonal conjugate gradient method preconditioned by an exterior Poisson solver and a direct sparse solver. The primary emphasis of this work is to provide design engineers with an aerodynamics analysis tool (thetranair code) which is as accurate, reliable, economical, and flexible to use as panel methods. Results obtained by usingtranair to analyse several interesting configurations are presented. This work was supported in part bynasa (Contractnas2-12513) and theirad funds of The Boeing Company.     

Effect of oxygen intercalation on properties of sputtered CuYO<Subscript>2</Subscript> for potential use as <Emphasis Type="Italic">p</Emphasis>-type transparent conducting films

Transparent films of copper yttrium oxide doped with 2% calcium have been prepared by rf magnetron sputtering. The films show a conductivity of 8 Scm⁻¹ on intercalation of oxygen at high pressure, which reduced the transparency in the visible region. The Ca-doped CuYO₂ films before oxygen intercalation show an average transmission of about 60% which reduces to about 45% upon oxygen intercalation. The temperature dependence of the conductivity indicates semiconductor behaviour with low activation energy of 0·59 eV at room temperature. The positive sign of Seebeck coefficient (+274 μVK⁻¹) confirms the p-type conductivity of the films. The optical bandgap of CuYO₂ was found to be 3·15 eV.     

Planning for the Subernarekha river system in eastern India

The study describes the systems studies carried out to plan a river basin in order to determine the nature and size of water storage facilities and releases for irrigation and industrial uses, and the associated cropping pattern. The model has been formulated in the framework of a linear programming model for a specific target year. This model is developed in the context of planning the Subernarekha river basin. The results are discussed and these provide information and insight suggesting the need for more disaggregated analysis of interaction between irrigation and related agroeconomic parameters.     

On the mechanism of pairing in thebcs theory

An explanation has been offered for the mechanism of cooper pairing in thebcs theory of superconductivity on the basis of the relativistic Darwin interaction. The theory leads to an expression for critical temperature which depends on a few atomic parameters. Calculated values ofT _c for elements and alloys are in good agreement with experiment.     

Plastic <Emphasis Type="Italic">n</Emphasis>-factor for three-point bend specimens: Analysis of instrumented Charpy impact test results for AISI 308 weld and AISI 316 stainless steels

In this paper, instrumented impact test results obtained using V-notch and precracked Charpy specimens of AISI 308 weld and AISI 316 stainless steels are analysed for determining the plastic -factor for three-point bend specimens used in J-integral evaluation. Tested 316 stainless steel specimens were in various thermal aging/cold-work conditions whereas 308 weld specimens were in the as-welded condition. The results are analysed using the various procedures proposed in the literature and compared with experimental and finite element results reported in the literature. Based on our analysis, two polynomial expressions of a/W for _pl are presented: one gives a sort of upper-bound in the a/W range 0.05–1.0 while the other gives conservative values (i.e., use of this results in J-R curves and J sufficiently conservative for engineering purposes). Both provide a smooth variation of _pl over the entire a/W range unlike some of the expressions given in the literature which show a discontinuous change at an intermediate a/W.     

<Emphasis Type="Italic">k</Emphasis>-Shortest routing of trains on shunting yards

We consider the problem of designing algorithmic support for k-best routing decisions in train shunting scheduling. A study at the Netherlands Railways revealed that planners like to interact with the solution process of finding suitable routes. Two types of interaction were required: the possibility of assigning specific tracks to a route and of preventing the assignment of specific tracks to a route. The paper develops insights in the structure of the cost matrix in this k-best optimization problem. These dominance results are used in a two stage k-shortest path algorithm to support this task of the shunting planners. The solution approach determines the optimal sequence of the tracks that manually have been added to the route and determines the k shortest paths in this network. The approach is implemented in a prototype of a support system for shunting planners. The required calculation times for practical instances of the problem with varying numbers of alternative solutions (k ≤ 8) and intermediate tracks (m ≤ 5) are between 0.1 and 1.4 s. These calculation times are acceptable to provide adequate support to the planners of these shunting yards. Supported by the Netherlands Railways, Project “Rintel 4a”. We gratefully acknowledge the management and planners of this company. Specifically, we would like to thank Dr. L.G. Kroon and the planners of location Zwolle for their willingness to co-operate.     

Applications of scanning transmission electron microscope microanalysis in the study of materials

The dedicatedstem equipped with field emission electron source, affords opportunities for the acquisition of microchemical and microstructural data on a scale approaching the nanometer level. In this presentation, a number of applications of microchemical analysis and microdiffraction to engineering materials will be discussed, with major emphasis on high-strength low-alloy steels, steels for high formability in automotive applications, and aluminium alloys. Some advantages and limitations of the technique are noted, especially for application to analysis of electrochemically prepared thin foils, and to the analysis of extracted particles.