Erratum to Stricker.

Reports an error in the article "The The Renin-Angiotensin System and Thirst: A Reevaluation. II. Drinking Elicited in Rats by Caval Ligation or Isoproterenol" by Edward M. Stricker (Journal of Comparative and Physiological Psychology, 1977, Vol. 91, No. 6, pp. 1220-1231), one line was printed incorrectly. On page 1228, the third line in the left-hand column reads "protin after 2 U/100 g hog renin"; the entire first sentence should read as follows: Three other nephrectomized rats were anesthetized 50 min after .33 mg/kg isoproterenol, 5 min after 2 U/100 g hog renin had been given. (The following abstract originally appeared in record 2005-09077-001) Ligation of the inferior vena cava and administration of isoproterenol have been shown to stimulate renin secretion and to augment water intake in rats. However, the present experiments suggested that the plasma renin activities produced by these treatments do not account for more than 20% of the observed drinking behavior. Direct measurements of arterial blood pressure further indicated that nephrectomized rats go into hypotensive shock after caval ligation or isoproterenol treatment. Drinking was elicited in these hypotensive animals by systemic injection of hypertonic NaCl solution, renin, or Pitressin, or by intracranial injection of angiotensin, but in each case a rapid increase in blood pressure also was observed. Thus, it appears that nephrectomy reduces water intake in these animals by undermining their general capacity to behave rather than by removing a specific dipsogenic stimulus. These and other results suggested that drinking elicited in rats by caval ligation or isoproterenol is not mediated by the renin-angiotensin system. (PsycINFO Database Record (c) 2010 APA, all rights reserved)