浅谈一种基于图形化的交互式云原生应用分发管理方案

本文提供一种图形化的交互式应用分发管理方法,涉及云原生应用的申请、分发、管理全部生命周期。它包括应用管理中心、应用使用终端2个部分;应用管理中心管理、分发应用,应用使用终端安装、监控应用。本文提供的方法使应用管理中心能全局监管所有应用使用终端的应用,并且能满足各个应用使用终端的定制化需求;采用简洁的可视化界面操作,屏蔽应用安装运维过程中涉及的底层环境和复杂的命令,可有效减少企业级应用的实施运维难度。     

基于PDM框架的应用集成研究与实践

以863/CIMS重大攻关项目“制造业CIMS应用集成平台”为应用背景,以企业内部的应用集成需求为目标,研究了采用产品数据管理系统作为应用集成框架的特点,讨论了PDM系统和典型应用系统集成的有关问题。在此基础上,本文建立了一个基于商用PDM系统针对计算机辅助应用系统的应用集成模式,并通过应用实例对其进行验证     

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对于RFID的标准和应用的关系,标准的建立要依据应用的情况,建立应用标准。我们要把应用放在首位,按照应用的需要去推进标准的建立。--戴定一副会长在第二届亚洲智能标签应用大会上说     

数字电视中间件应用管理器的研究

介绍了中间件应用管理器的功能描述和结构设计方法.本文还介绍包括Xlet应用模型、携带应用信令的应用列表以及如何从传输流中提取应用列表的方法.     

CREO软件在钣金零件设计中的应用

介绍了CREO软件在钣金零件设计中的应用,具体包括族表的应用、展平特征的应用、孔表的应用。对CERO软件族表与AutoCAD软件动态块进行了对比分析,确认应用CERO软件族表设计钣金零件相比应用AutoCAD软件动态块,更具优势。     

CAPPFramework设计与实现

CAPP应用框架与开发平台 (CAPPFram ework)是一个通用交互式 CAPP应用支撑软件 ,它确立了 CAPP应用系统的基本框架、基本工作流程和基本功能 ,并提供了应用开发工具。本文介绍了 CAPPFramework的基本目标、组成 ;基于CAPPFramework的 CA PP应用系统开发模型 ;CAPP应用系统软件结构以及基于C/ S模式的 CAPPFram ework应用系统结构。     

在机械电气控制装置中PLC技术的作用及其应用探讨

在现代化科学技术的发展带动下,PLC技术被广泛分应用到电气装置的控制中,在其应用下,有效地提升了装置应用的效率,在一定程度上为企业的发展带来了经济效益。在这种背景下,要想保障机械装置的应用,就应该在其应用中注重对应用中的技术以及在现实应用中的作用探究,通过对其作用的探究,及时的找到适合技术应用的方法和策略,保障生产效率提升。鉴于此,本文针对机械电气控制装置中的PLC技术应用的作用以及技术应用的策略进行了探讨。首先,在其技术应用作用的分析中,以两方面分析做了阐述;其次,针对其技术应用的形式分析中,从五个方面做出了分析。希望在本文的研究帮助下,能够提升PLC技术在电气控制装置中的应用效率。     

人工神经网络在机械加工中的应用

介绍神经网络技术在机械加工领域的应用现状,包括人工神经网络在工艺规程编制中的应用、在加工参数优化中的应用及在工况监测及预报中的应用。并对这项技术的应用作了进一步展望。     

信息技术在农机技术推广中的应用分析

针对信息技术在农机技术推广中的应用进行分析,阐述了当前我国信息技术在农机技术推广应用的必要性,同时提出了农机技术应用的缺陷。结合这些内容,总结了信息技术在农机技术推广中的应用,主要包括:信息化在智能农机中的应用和信息化在农机监控中的应用两部分内容,希望通过对这些内容的分析,能够推动信息技术在农机技术推广中的充分应用。     

2010年中国企业信息化指数调研报告

信息技术应用范围扩大拉动信息化总体成熟度拔升 "中国企业信息化成熟度指数受信息技术应用状态、应用范围和应用效益三方面影响."     

Differential expression of CD95, Bcl-2, and Bax in rat gastric chief and parietal cells

Apoptotic cell death is common in the inflamed gastric mucosa, but its role in the regulation of cell homeostasis in normal gastric mucosa is unknown. We investigated the expression of CD95, Bcl-2, and Bax and their roles in the regulation of apoptosis in normal rat gastric mucosa and in cultures of highly enriched rat chief and parietal cells by immunostaining, Western blotting, and FACS. In intact tissue CD95, Bcl-2, and Bax were localized predominantly in the glandular base region in chief cells. In freshly isolated cells, expression of CD95, Bcl-2, and Bax was much more pronounced in chief cells than in parietal cells. A lower intracellular Bcl-2/Bax ratio suggesting a higher susceptibility to apoptosis was noticed in chief rather than in parietal cells. In extended cultures of parietal and chief cells, Bax expression was upregulated and Bcl-2 expression was downregulated. These regulatory changes, presumably caused by in vitro effects, were not associated with an increase in spontaneous apoptosis. Treatment of chief and parietal cells with Fas-ligand induced apoptosis of all CD95 expressing cells. Expression of CD95, Bcl-2, and Bax predominantly in chief cells suggests that in this cell type regulation of apoptosis may differ from that in parietal cells. Binding of FasL with functionally active CD95 receptors on chief and parietal cells may be relevant for induction of apoptosis in inflamed gastric mucosa.     

Extracellular breakdown of collagen by mice decidual cells. A cytochemical and ultrastructural study.

The interaction of antimesometrial decidual cells and collagen fibrils was studied by light microscopy and ultrastructural cytochemistry in fed and acutely fasted mice on days 9-11 of pregnancy. Fibrillar elements in the extracellular space consisted of collagen fibrils and filamentous aggregates (disintegrating collagen fibrils). Intracellular vacuoles exhibited typical collagen immersed in electron-translucent material (clear vacuoles) and faint cross-banded collagen immersed in electron-opaque material (dark vacuoles). Fibrillar elements showed extracellular acid phosphatase activity which was stronger in the region of mature decidua than in predecidual cells region in all animals; it was conspicuous in mature decidua of fasted animals. Intracellular acid phosphatase activity was observed in dark vacuoles and lysosomes, and was absent in clear vacuoles in all cells studied. Since acid phosphatase activity reflects the presence of lysosomal hydrolases in general, the results indicate that breakdown of extracellular collagen occurs by release of lysosomal enzymes by decidual cells and also by internalization of collagen for intracellular degradation in fed and fasted mice. Collagen breakdown may be part of the process of tissue remodeling in mature and predecidual regions, however, in mature decidua, collagen breakdown is enhanced and may therefore contribute to nutrition of the fetus, specially in acutely fasted mice.     

Histochemical and ultrahistochemical localization of heavy metals in calf organs

Cadmium, zinc, selenium, and copper were administered, singly or in combination, orally or subcutaneously. Experiment I included 32 calves of both sexes; six received Cd (two groups), Zn, Cd, and Zn, and Cd and Se (two groups) and one group was a control. In Experiment II (21 bulls), three were given Cd, Cd, and Cu, and Cd and Zn, respectively, and one group was a control. For light microscopy, in Experiment I the highest amounts of silver granules were present in the samples of liver, small intestine, and vesicular gland of all the exposed groups; in Experiment II the most affected organs were liver, kidney, and small intestine. For electron microscopy, in Experiment I, after administration of Cd and Zn, the highest amounts of granules were seen in the cytoplasm of hepatocytes and cells of the proximal and distal renal tubules and the lowest amounts were found in glandular cells of the pancreas. Administration of Cd and Se resulted in the presence of large numbers of granules in the nuclei and nucleoli of spermatogonies. In Experiment II, ingestion of Cd and Zn in feed led to the appearance of highest amounts of granules in the nucleoli, nuclei, and cytoplasm of cells in testes, kidneys, and pancreas. Following Cd intake, the highest accumulation of granules was observed in the nucleoli of hepatocytes and cells of the proximal and distal renal tubules. Combined Cd and Cu produced the highest number of granules in cells of the proximal and distal renal tubules and in the nucleoli and nuclei of germinal epithelium.     

Mechanotransduction-The relationship between gravity,cells and tensile loading in extracellular matrix

Gravity plays a central role in vertebrate development and evolution. Mechanotransduction involves the tensile tethering of veins and arteries, connections between the epidermis and dermis in skin, tensile stress concentrations that occur at tissue interfaces, cell-cell interactions, cell-collagen fiber stress transfer in extracellular matrix and fluid shear flow. While attention in the past has been directed at understanding the myriad of biochemical players associated with mechanotransduction pathways, less attention has been focused on determining the tensile mechanical behavior of tissues in vivo. Fibroblasts sit on the surface of collagen fibers in living skin and exert a retractile force on the fibers. This retractile force pulls against the tension in collagen fibers in skin. After fibroblast-collagen fiber interactions are altered either by changes in fibroblast adhesion or after formation of cancer associated fibroblasts, and changes in cell junctions, alterations in the retractive force leads to changes in mechanotransduction. The purpose of this paper is to present a model of tensile forces that occur at the fibroblast-collagen fiber interface and how these forces are important in extracellular matrix physiology in health and disease.     

Effects of humidity on nanometer scale wear of a carbon film

Influence of environmental humidity on scanning-scratched wear tests of a carbon film deposited by electron cyclotron resonance plasma sputtering are evaluated in both air and nitrogen with an atomic force microscope and a diamond tip. Wear depth is larger in higher humidity and also larger in air than in nitrogen. Effect of humidity on scratch load dependence and repeated scanning-scratch tests are larger in nitrogen than in air. Effect of humidity on wear is clearer in the repeated scanning-scratch test than in the scratch load dependence test especially in air, and also clearer at larger scratch load. In scratch velocity dependence test, there is a tendency that wear depth decreases with increase in logarithm of scratch velocity both in air and nitrogen. Wear models to explain the experimental results are discussed.     

Dynamic structural changes of synaptic contacts in the visual system of insects

The visual system of insects provides an excellent model to study processes of transduction and transmission of photic information, synaptogenesis, synaptic plasticity, and wiring between photoreceptors and their visual interneurons in the optic lobe. This review describes synaptic contacts between photoreceptors and other neurons in the visual system of insects, especially in the fly's first optic neuropile (the lamina), and summarizes changes observed in the synapses of visual cells that have been reported both in phylogeny and ontogeny, and also examples of synaptic plasticity in adult insects that have been evoked by intrinsic and extrinsic factors. Plasticity observed in synapses of the insect's visual system seems to exemplify not only synaptic contacts in insects but, given that similar examples of plasticity have been found in other animal groups, may also be a general phenomenon in the nervous system.     

The intracellular distribution of ions and water in rat liver and heart muscle

Local dry mass concentrations of intracellular compartments in rat heart muscle and liver cells were estimated by quantitative electron microscopy and X-ray microanalysis of ultrathin frozen-dried cryosections. The results were used to calculate elemental concentrations per litre of compartment water from the X-ray microanalytical data. Water fractions were between 80.3 ± 1.3% of wet weight in the decondensed chromatin and only 45.1 ± 1.7% in mitochondria of liver cells. The lowest water fraction in heart muscle cells was also found in mitochondria. The ionic concentrations found in the cytoplasm of liver cells and in the myofibrils are in accord with the electroneutrality rule and in osmotic equilibrium with the extracellular concentrations. The concentrations of Na, K, Cl and P both in the cytoplasm and in the regions of decondensed chromatin within the nuclei were found to be equal. However, in regions of condensed chromatin K⁺ concentrations were found to be much higher than expected for a Donnan distribution of ions free in solution. Most probably the activity coefficient for K⁺ is lower in the condensed chromatin than in the decondensed or in the cytoplasm. The same holds true for the A-band as compared to the I-band in heart muscle cells. A sequestration of K⁺ was measured also in the rough endoplasmic reticulum (RER) of hepatocytes. The Cl^? concentration in mitochondria both in heart muscle and liver cells has been measured far in excess of what might be expected from a Nernstian distribution. A coupled inward Cl^? transport in mitochondria must, therefore, be assumed.     

Ciliary neurotrophic factor increases the survival of magnocellular vasopressin and oxytocin neurons in rat supraoptic nucleus in organotypic cultures.

Organotypic cultures of the rat hypothalamus are very useful models for the long-term study of parvocellular vasopressin (VP) neurons in the paraventricular (PVN) and suprachiasmatic (SCN) nuclei. However, they do not preserve significant numbers of VP magnocellular neurons (VP-MCNs) in either the PVN or the supraoptic nucleus (SON). Vutskits et al. [(1998) Neuroscience 87:571-582] reported that ciliary neurotrophic factor (CNTF) was a selective survival factor for rat VP-MCNs in organotypic cultures of the rat hypothalamic paraventricular nucleus (PVN). We examined the effects of CNTF on the survival of these neurons in rat and mouse SONs. CNTF (10 ng/ml) in the culture media increased the survival of VP-MCNs by 6-fold and OT-MCNs by 3-fold. In the mouse, both OT- and VP-MCNs survive very well in organotypic cultures under standard culture conditions and the addition of CNTF had no further effect. Consistent with these results, in situ hybridization showed substantially higher levels of VP- and OT-mRNA in rat PVNs and SONs in the presence of CNTF, but produced no changes in these nuclei in the mouse. The optimum period for the survival effect of CNTF on MCNs in the rat hypothalamic cultures was in the first 7-10 days of culture and this effect is maintained for at least 5 additional days if CNTF is then removed from the medium. Therefore, using CNTF in the culture media can provide an opportunity for long-term studies of rat VP- and OT-MCNs in SONs in organotypic cultures.     

Distribution of sex steroid hormone receptors in the avian brain: functional implications for neural sex differences and sexual behaviors

Developmental and seasonal changes in the production of androgens, estrogens, and progestins seem to control sex-specific differentiation and seasonal changes in appetitive and consummatory sexual behaviors of birds. This results in profound sex differences in the quality (sex-specific) or quantity (sex-typical) of behaviors such as courtship, territoriality, or copulation. Steroids affect the brain by binding to intracellularly located receptors. The same brain areas express androgen, estrogen, and progesterone receptors in male and female brains. Sex differences in these genetically determined patterns occur in the size of neuron populations that intrinsically express sex steroid receptors. Further permanent sex differences are subsequent to degenerative fates of receptor expressing neuron populations during ontogeny. Transient sex differences in receptor expression appear to be due to area-specific up- and down-regulation of receptor levels, reflecting transient changes in the level of circulating steroids, changes in environmental conditions, or in the physiological status of the individuals. In particular, intrinsic sex differences in the expression pattern of sex steroid receptors and steroid-independent regulation of the expression level of these receptors in the brain are limiting mechanisms for gonad-dependent sexual development and activities.