Chemical constituents of Aralia fargesii Franch

From the EtOH extract of Aralia fargesii, 8 compounds were isolated and identified as umbelliferone, esculetin, scopoletin, scoparone, oleanic acid, falcarindiol, mellissic acid and beta-sitosterol.     

Chemical constituents of Clematis intricata Bunge

Five compounds were isolated from the aerial part of Clematis intricata for the first time. On the basis of spectral data (UV, IR, MS, 1HNMR and 13CNMR), they were identified as scopoletin, caffeic acid, inositol, 1-tria-contanol and beta-sitosterol.     

Chemical constituents of Rosa laevigata Michx

Six compounds were isolated from Rosa laevigata. Five of them were obtained from the ethanolic extract and identified as 2 alpha, 3 beta, 19 alpha, 23-tetrahydroxyurs-12-en-28-oic acid, 2 alpha, 3 alpha, 19 alpha, 23-tetrahydroxyurs-12-en-28-oic acid, euscaphic acid, beta-sitosterol and daucosterol. The other one was obtained from the acetate of emulsive layer of the petroleum ether and elucidared as 2 alpha, 3 beta-dihydrolup-28-methyl ester diacetate.     

HPLC determination of five constituents in plants of genus Ligusticum

A RP-HPLC method was established to separate and determine five constituents in plants of genus Ligusticum by using an ODS column (Hypersil-C18, 5 microns) and acetonitrile (containing 1.25% CHCl3)--water (saturated with CHCl3) as mobile phase for gradient elution. The five constituents were ferulic acid, scopoletin, 3-butyl-phthalide, ligustilide, and diligustide. They were detected at 284 nm. Peak purity was monitored by photodiode array detector. Benzthiazide was used as the internal standard. The method is simple, fast, sensitive and reproducible.     

Chemical constituents of Aster albscens Hand.-Mazz

Four compounds, stigmasterol, D-hurulon-14-en-3-ol, stigma-delta7.22-dien-3beta-palmitate and friedelin were isolated from the root of Aster albscens for the first time. Their structures were elucidated by spectral methods.     

Chemical constituents from the bark of Hibiscus syriacus L

Seven constituents (I-VII) were isolated from the bark of Hibiscus syriacus and identified as nonanedioic acid (I), suberic acid (II), 1-octarcosanol (III), beta-sitosterol (IV), 1,22-docosanediol (V), betulin (VI) and erythrotriol (VII). VII was obtained from the plant for the first time, I, II, III and VI were isolated from Malvaceae plants for the first time.     

Chemical constituents of Luffa cylindrica (L.) Roem

Six compounds were isolated from the fruits of Luffa cylindrica. They were identified as lucyosides C, E, F, H, a mixture of alpha-spinasterol and stigmasta-7,22,25-trien-3 beta-OH and a mixture of alpha-spinasteryl glucoside and delta 7,22,25-stigmasteryl-beta-D-glucoside by means of chemical evidence and spectral analysis.     

Chemical constituents of Eclipta alba (L.) Hassk

Ecliptasaponin C (1), a new triterpenoid glucoside, was isolated together with daucosterol (2) and stigmasterol-3-O-glucoside (3) from Eclipta alba. Based on spectral analysis, chemical evidence and hydrolytic results, it's structure was deduced as 3-beta-O-beta-D-glucopyranosyl-19beta-hydroxy olean-12-ene-28-oic acid 28-O-beta-D-glucopyranoside, Compounds 2 and 3 were obtained from Eclipta for the fist time.     

Studies on constituents of medicinal plants. XVI. The constituents of Spiraea species (author''s transl)

A rare case of downward displacement of the left kidney caused by marked development of an ectopic ovarian cyst in the left subphrenic region is presented. Exact diagnosis could not be made preoperatively but a satisfactory result was obtained by removal of the cyst. Histological diagnosis of the tumor was serous cystadenoma arising from the left ovary.     

Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin

CNS activity of swertiamarin, a secoiridoid glucoside from Swertia chirata, was evaluated. An apparent anomaly, associated with the unanticipated finding that the alcoholic extracts (excluding mangiferin) of S. chirata significantly reversed the mangiferin-induced CNS-stimulating effects in albino mice and rats, was resolved. The results indicate that swertiamarin and mangiferin antagonize each other in vivo and thereby reverse their CNS effects.     

Chemical constituents from the aerial part of Epimedium brevicornum Maxim

Six flavonoids were isolated from the aerial part of Epimedium brevicornum and identified as baohuo side I, 2"' O-rhamnosyl icariside II, sagittatoside B, baohuoside II, ikarisoside F and ikarisoside C by means of UV, IR, 1H-NMR, 13C-NMR and FAB-MS spectral analysis, they were isolated from this plant for the first time.     

Antiproliferative constituents in umbelliferae plants. IV. Constituents in the fruits of Anthriscus sylvestris Hoffm

The constituents in the fruit of Anthriscus sylvestris Hoffm. were investigated, and four lignans [deoxypodophyllotoxin, morelensin, (-)-deoxypodorhizone, and (-)-hinokinin], one phenylpropanoid [1-(3',4'-dimethoxyphenyl)-1 xi-hydroxy-2-propene], two phenylpropanoid esters [3',4'-dimethoxycinnamyl (Z)-2-angeloyloxymethyl-2-butenoate and 3',4'-dimethoxycinnamyl (Z)-2-tigloyloxymethyl-2-butenoate], and one polyacetylenic compound (falcarindiol) were isolated. Their antiproliferative activity against MK-1, HeLa and B16F10 cell lines is reported.     

Chemical constituents of Taxus yunnanensis Cheng et L. K. Fu

Five compounds were isolated from the bark of Taxus yunnanensis. Their structures were identified on the basis of spectral analysis and physico-chemical constants as taxol C-7-xylose, taxol B, 10-deacetyl baccatin III, taxusin and 2R,3R-catechin.     

Chemical constituents of Epimedium wanshanense S. Z. He et Guo

Five flavonoids were isolated from Epimedium wanshanense and identified as sagittatoside B, anhydroicaritin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-rhamnopyranoside, sagittatoside A, ikarisoside B and desmethylanhydroicaritin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L- rhamnopyranoside by means of IR, UV, 1HNMR, 13CNMR, MS and chemical evidence. They were obtained from this plant for the first time.     

A taste of Chinese medicine!

We report a case of profound anticoagulation caused by interaction between warfarin and danshen, a widely used Chinese herbal medicine, in a patient who had undergone mitral valve replacement. Patients taking warfarin should be warned not to take this herb. In addition, physicians should be alert to the possibility of an interaction with herbal medicine when anticoagulation control becomes difficult and no other causes are apparent.     

Chemical constituents in roots of Ampelopsis sinica (Miq.) W.T. Wang

Six compounds were isolated from the roots of Ampelopsis sinica and identified as lupeol, beta-sitosterol, daucosterol, catechin, sucrose and palmitic acid on the basis of spectroscopic. Lupeol is found in Ampelopsis genus for the rirst time.