共查询到20条相似文献,搜索用时 15 毫秒
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Nano or microsized particles have been a research focus for decades, and the advancement of microfluidic technologies provides alternative strategies for the synthesis of such materials for various applications. Recent advances of using different microfluidic devices (MDs), including continuous laminar flow, segmented flow, droplet‐based, and other non‐chip‐based microreactors, for the synthesis of nano or microsized particles with specific properties are reviewed, along with their biomedical applications. Different categories of particles fabricated in MDs are summarized to highlight the wide application of the processing platform in the development of novel functional materials. 相似文献
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Chen GD Fachin F Fernandez-Suarez M Wardle BL Toner M 《Small (Weinheim an der Bergstrasse, Germany)》2011,7(8):1061-1067
Solid materials, such as silicon, glass, and polymers, dominate as structural elements in microsystems including microfluidics. Porous elements have been limited to membranes sandwiched between microchannel layers or polymer monoliths. This paper reports the use of micropatterned carbon-nanotube forests confined inside microfluidic channels for mechanically and/or chemically capturing particles ranging over three orders of magnitude in size. Nanoparticles below the internanotube spacing (80 nm) of the forest can penetrate inside the forest and interact with the large surface area created by individual nanotubes. For larger particles (>80 nm), the ultrahigh porosity of the nanotube elements reduces the fluid boundary layer and enhances particle-structure interactions on the outer surface of the patterned nanoporous elements. Specific biomolecular recognition is demonstrated using cells (≈10 μm), bacteria (≈1 μm), and viral-sized particles (≈40 nm) using both effects. This technology can provide unprecedented control of bioseparation processes to access bioparticles of interest, opening new pathways for both research and point-of-care diagnostics. 相似文献
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羟基磷灰石是人体骨骼的主要无机成分,具有良好的生物相容性和生物活性,能与新生骨形成很强的化学键合,是植入生物陶瓷材料研究的重点物质之一。微波烧结具有快速加热,能量利用率高,操作简便,过程易于控制等特点,被誉为“21世纪新一代烧结技术”。综述了微波烧结的基本原理,以及国内外微波法制备纳米羟基磷灰石的研究进展,提出了有待解决的问题。 相似文献
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Juergen Biener Subho Dasgupta Lihua Shao Di Wang Marcus A. Worsley Arne Wittstock Jonathan R. I. Lee Monika M. Biener Christine A. Orme Sergei O. Kucheyev Brandon C. Wood Trevor M. Willey Alex V. Hamza Jörg Weissmüller Horst Hahn Theodore F. Baumann 《Advanced materials (Deerfield Beach, Fla.)》2012,24(37):5083-5087
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Juergen Biener Subho Dasgupta Lihua Shao Di Wang Marcus A. Worsley Arne Wittstock Jonathan R. I. Lee Monika M. Biener Christine A. Orme Sergei O. Kucheyev Brandon C. Wood Trevor M. Willey Alex V. Hamza Jörg Weissmüller Horst Hahn Theodore F. Baumann 《Advanced materials (Deerfield Beach, Fla.)》2012,24(37):5017-5017
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Junhyun Kim Sang Min Park Dongwhi Choi Dong Sung Kim 《Small (Weinheim an der Bergstrasse, Germany)》2020,16(22)
In the field of micro‐nanofluidics, a freestanding configuration of a nanoporous junction is highly demanded to increase the design flexibility of the microscale device and the interfacial area between the nanoporous junction and microchannels, thereby improving the functionality and performance. This work first reports direct fabrication and incorporation of a freestanding nanoporous junction in a microfluidic device by performing an electrolyte‐assisted electrospinning process to fabricate a freestanding nanofiber membrane and subsequently impregnating the nanofiber membrane with a nanoporous precursor material followed by a solidification process. This process also enables to readily control the geometry of the nanoporous junction depending on its application. By these advantages, vertically stacked 3D micro‐nanofluidic devices with complex configurations are easily achieved. To demonstrate the broad applicability of this process in various research fields, a reverse electrodialysis‐based energy harvester and an ion concentration polarization‐based preconcentrator are produced. The freestanding Nafion‐polyvinylidene fluoride nanofiber membrane (F‐NPNM) energy harvester generates a high power (59.87 nW) owing to the enlarged interfacial area. Besides, 3D multiplexed and multi‐stacked F‐NPNM preconcentrators accumulate multiple preconcentrated plugs that can increase the operating sample volume and the degree of freedom of handling. Hence, the proposed process is expected to contribute to numerous research fields related to micro‐nanofluidics in the future. 相似文献
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Tsung-Ting Tsai Shu-Wei Shen Chao-Min Cheng Chien-Fu Chen 《Science and Technology of Advanced Materials》2013,14(4)
AbstractA colorimetric sensing strategy employing gold nanoparticles and a paper assay platform has been developed for tuberculosis diagnosis. Unmodified gold nanoparticles and single-stranded detection oligonucleotides are used to achieve rapid diagnosis without complicated and time-consuming thiolated or other surface-modified probe preparation processes. To eliminate the use of sophisticated equipment for data analysis, the color variance for multiple detection results was simultaneously collected and concentrated on cellulose paper with the data readout transmitted for cloud computing via a smartphone. The results show that the 2.6 nM tuberculosis mycobacterium target sequences extracted from patients can easily be detected, and the turnaround time after the human DNA is extracted from clinical samples was approximately 1 h. 相似文献
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Dechao Chen Shoucong Ning Jiao Lan Ming Peng Huigao Duan Anlian Pan Yongwen Tan 《Advanced materials (Deerfield Beach, Fla.)》2020,32(46):2004055
Although 2D layered metal compounds are widely exploited using various techniques such as exfoliation and vapor-phase-assisted growth, it is still challenging to construct the 2D materials in a 3D configuration with preservation of the unique physicochemical properties of the metal compounds. Herein, a general synthetic strategy is reported for a wide variety of 2D (atomic-scale thickness) metal compounds with 3D bicontinous nanoporous structure. 19 binary compounds including sulfides, selenides, tellurides, carbides, and nitrides, and five alloyed compounds, are successfully prepared via a surface alloy strategy, which are readily created by using a recyclable nanoporous gold assisted chemical vapor deposition process. These 3D nanoporous metal compounds with preserved 2D physicochemical properties, tunable pore sizes, and compositions for electrocatalytic applications, show excellent catalytic performance in the electrochemical N2 reduction reaction. This work opens up a promising avenue for fundamental studies and potential applications of a wide variety of nanoporous metal compounds. 相似文献
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Posadas MA Hahn D Schleuter W Paparello J 《Hemodialysis international. International Symposium on Home Hemodialysis》2011,15(3):416-423
We present a case of a 51-year-old woman who developed thrombocytopenia associated with dialysis treatments. Laboratory values revealed a platelet count of 50,000 or less postdialysis, with recovery of platelet count during her interdialytic period. An extensive work up including infectious serology and heparin-induced thrombocytopenia test was negative. Based on the pattern of thrombocytopenia and negative work-up, it is concluded that her thrombocytopenia was due to her dialysis treatments. We discuss the literature on thrombocytopenia and hemodialysis and postulate that our patient had a reaction to her dialyzer membrane or to the electron beam radiation method used to sterilize her dialyzer. 相似文献
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