Integrating behavioral and social sciences research at the National Institutes of Health, U.S.A

Readers of Social Science & Medicine may find it interesting to know that in 1993 the United States Congress established the Office of Behavioral and Social Sciences Research (OBSSR) at the National Institutes of Health (NIH) in the belief that scientific research on behavioral and social factors in order to facilitate a growth in this important area of research. As is discussed in this paper, the philosophy of the OBSSR is that, although discoveries in the behavioral and social sciences are as critical for health as those from the biomedical sciences, knowledge from both areas must ultimately be integrated. Such integration will accelerate our understanding and treatment of physical and mental illnesses in both the developed and the developing world. This paper briefly presents the scientific evidence supporting this philosophy, outlines the mandated responsibilities of the OBSSR, and discusses some of its current and planned activities.     

HIV risk behaviors: a comparison of U.S. Hispanic and Dominican Republic youth

Using 3-week-old male beagle dogs, we examined the cartilage-bone replacement processes in the mandibular condyle by means of light and electron microscopy. Calcification of the cartilage matrix occurred in the central area of the longitudinal septa, but not in the transverse septa. Perivascular mononuclear cells absorbed the transverse septa which initiated the opening of the chondrocytic lacunae. These cells phagocytosed septal cartilage fragments. Shortly thereafter, a thin bone layer was deposited on the remaining longitudinal septa by invading osteoblasts. Osteoclasts in lacunae developed neither ruffled borders nor clear zones in the cartilage matrix, but once the bone layer has been deposited in the remaining cartilage, these structures formed. Our results suggest that the cartilage-bone replacement in mandibular condyle involves three sequential processes: 1) degradation and phagocytosis of cartilage fragments in the transverse septa by mononuclear cells, 2) bone deposition over the remaining longitudinal septa, and 3) degradation of both calcified cartilage and bone by osteoclasts.     

NIDA's HIV prevention programs.

Comments on the review by J. A. Kelly et al (see record 1994-10963-001) regarding HIV prevention programs. Programs that Kelly et al did not describe are discussed, focusing on the large-scale community trials coordinated by the National Institute on Drug Abuse (NIDA) for injection drug users, crack users, and sex partners of drug users. R. H. Needle et al agree that stronger partnerships should be forged between research and community organizations and that dissemination of successful strategies should be improved. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Primary prevention in aircraft disasters: Integrating research and practice.

The integration of rigorous scientific research with program development and implementation is essential in new areas of psychological practice, such as primary prevention for aircraft disaster victims. Research on primary prevention for air disasters can provide practical information on how to help victims cope with traumatic events, as well as contributing to theoretical understanding about the role of trauma in the development of psychopathology. Both epidemiological research on the mental health effects of disasters and practitioner experiences are used in this article to identify high risk groups and types of primary prevention interventions for air disasters. Practical suggestions are provided for research in this area, including discussions of design issues, access to victims, selection of instruments, and issues involved in obtaining funding. Implications of media attention and litigation also are considered. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Allele frequencies and molecular diagnosis in haemophilia A and B patients from Russia and from some Asian republics of the former U.S.S.R

Using the C.B.17 scid mouse strain, we have developed a model of disseminated leukaemia and myeloma using five human cell lines, CCRF-Cem, Molt-4, Raji, IM9 and HS-Sultan. Introduction of any of these cell lines by either an intravenous or an intraperitoneal route eventually kills the mouse due to leukaemia or myeloma cell load. Neoplastic cells can be found in the blood, liver and bone marrow. Intraperitoneal transfer produces a local solid tumour whereas intravenous transfer produces foci of neoplastic cells in the spine and brain. A single dose of melphalan is able to increase survival time from infection of a lethal dose of the T-cell leukaemia cell line, CCRF-Cem.     

Cost analysis and HIV prevention interventions.

Comments on the review by J. A. Kelly et al (see record 1994-10963-001) regarding public health interventions designed to prevent, reduce, or eliminate behavior that put individuals at risk for becoming HIV-infected. D. R. Holtgrave expands on the review by discussing important economic policy issues, including the cost of HIV prevention interventions and the societal economic benefits of prevention programs. Methods for estimating the cost of an HIV prevention intervention are described. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Physician migration to the U.S.--foreign aid for U.S. manpower

Data were obtained from the American Medical Association on Iranian physicians practicing in the U.S., and from the Iranian Medical Registry on U.S.-trained Iranian physicians who have returned to practice in Iran. There were 2,066 Iranian physicians practicing in the U.S. in 1972, 1,234 (60%) of whom were not undergoing any training. Only 600 of Iran's 9,535 physicians in 1972 had been trained in the United States. Thus, less than one-third of the specialists who have completed training in the U.S. have returned to practice in Iran. The specialist group with the highest rate of return is the combined surgery subspecialties (neurosurgery, thoracic surgery, orthopedic surgery, and plastic surgery). The specialist groups with the lowest rates of return were pathology, anesthesiology, and psychiatry. A comparison is made of the manpower problems Iran faces and the American problems in the area of physician manpower.     

The official American guidelines for prevention of nosocomial pneumonia. U. S. Centers for Disease Control

The official German guidelines for prevention of nosocomial pneumonia were published by the Bundesgesundheitsamt, now called Robert-Koch-Institut, twelve years ago. The recently published official "guidelines for prevention of nosocomial pneumonia" of the Centers for Disease Control and Prevention (CDC) are categorized according to scientific evidence. The American guidelines are very detailed and differ in some aspects from the official German guidelines. The purpose of the present paper is to inform the German anaesthesiologist about the official CDC guidelines and to provide a renewed background for the prevention of nosocomial pneumonia.     

Violence and U.S. regional culture.

The US South, and western regions of the US initially settled by Southerners, are more violent than the rest of the country. Homicide rates for White Southern males are substantially higher than those for White Northern males, especially in rural areas. But only for argument-related homicides are Southern rates higher. Southerners do not endorse violence more than do Northerners when survey questions are expressed in general terms, but they are more inclined to endorse violence for protection and in response to insults. Southern Ss responded with more apparent anger to insults than did Northerners and were more likely to propose violent solutions to conflicts presented in scenarios after being insulted. The social matrix that produced this pattern may be the culture of honor characteristic of particular economic circumstances, including the herding society of the early South. Consistent with this possibility, the herding regions of the South are still the most violent. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

U.S. psychology and world psychology.

Contends that although US psychology at present occupies a major position in world psychology, the field is growing more rapidly in many other countries. An example of international cooperation in an endeavor that could not be achieved by the psychological community of any single nation (i.e., securing the admission of the International Union of Psychological Science to the International Council of Scientific Unions) is given. A list of suggestions is presented outlining ways in which individual psychologists can take part in international psychological activities. (17 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Deep dyslexia and the right hemisphere hypothesis: Evidence from the U.S.A. and the U.S.S.R.

Discusses the theory that asserts that the residual reading abilities seen in deep dyslexia entirely reflect the operation of an intact right hemisphere reading system rather than a partially disabled left hemisphere reading system. Evidence from an experiment with normal Ss in a report by the present author and colleagues (1983) is presented, which suggests that the right hemisphere contains no lexical entries for abbreviations that can be accessed by visual presentation. Data are presented from studies by K. E. Patterson (1980; see also PA, Vols 63:12203 and 64:10691) on 2 male deep dyslexic's understanding of printed abbreviations, along with observations of a young female deep dyslexic who was tested on understanding of abbreviations and on letter-naming abilities. Considerable sparing of the ability to obtain semantic information from printed abbreviations was evidenced in all 3 Ss. This contrast suggests that the current right hemisphere account of the residual reading abilities seen in deep dyslexia is not a sufficient one and should be modified. (French abstract) (29 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Helping in 36 U.S. cities.

A series of experiments examined the relationship of urbanism to helping. Six types of helping behaviors were studied in a cross-sample of 36 small, medium, and large cities across the United States. The relationship of helping to a series of statistics reflecting the demographic, social, environmental, and economic characteristics of these communities was then examined. The strongest and most consistent predictor of overall helping was population density. There were significant correlations between economic indicators and helping in 3 situations. Helping in some situations also tended to be negatively related to violent crime rates and to environmental problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Development of the role of occupational health nursing in the U.S. and future perspectives in the U.S. and Japan

From 1988 to 1995, a bronchial washing was performed on 118 cases of middle lobe syndrome at the National Himeji Hospital. Twenty cases (16.9%) were positive for Mycobacterium avium complex (MAC). All cases were middle-aged (mean age 54.8), non-smoking women. Fourteen cases were asymptomatic and showed only abnormal shadow on chest X-ray film, while others complained cough, sputum or hemosputum. CT examinations were done on 13 patients, and pulmonary infiltrations were found in addition to right middle lobe or lingula in many cases. It is important to note that MAC infection might be one of causes of middle lobe syndrome.     

2000年美国钨市概览

仲钨酸铵/氧化物/碳化钨粉/矿石和精矿/其他/钨铁/钨粉/废料和废金属/图1 2000年美国进口的钨材料