阳离子季铵型表面活性剂对PVDF/PHEMA共混微滤膜的成膜性能研究

采用凝胶相转化法,以聚偏二氟乙烯(PVDF)/聚甲基丙烯酸-2-羟基乙酯(PHE-MA)共混合金为膜材料,N,N-二甲基乙酰胺(DMAc)为溶剂,阳离子季铵型表面活性剂(TM)为添加剂制备微滤膜.考察了添加剂浓度对铸膜液相容性、铸膜液黏度、铸膜液凝胶速度、膜结构和性能的影响.对PVDF/PHEMA/DMAc铸膜液体系中TM添加剂的作用规律进行了研究.实验发现:TM添加质量分数小于5.0%时,铸膜液中组分的相容性得到很大改善,制备出的微滤膜表面孔径均一、孔密度高.随着TM添加浓度的增大,铸膜液黏度先减小后增大,凝胶速度逐渐增大,膜的纯水通量先增大后减小,截留率则始终上升.     

Optimizing hydrogen-bonding miscible binary polymer blends made by concentrated emulsion polymerization

Polystyrene/poly (n-butyl methacrylate) blends were prepared by concentrated emulsion polymerization using (2-hydroxy ethyl) methacrylate and n-butyl methacrylate as hydrogen-bond donor and acceptor respectively. Two concentrated emulsions of styrene/(2-hydroxy ethyl) methacrylate and n-butyl methacrylate monomers were prepared separately, and mixed mechanically after partial polymerization. The products thus obtained consisted of compact particles. The specific formation of hydrogen bond between poly [styrene-co- (2-hydroxy ethyl) methacrylate] with poly (n-butyl methacrylate) were studied by transmission electron microscope and dynamic mechanical thermal analysis. The results showed that the miscibility is induced via hydrogen bonding between the hydroxyl group and the carbonyl groups and that hydrogen bonding plays an important role in the compatibilization of the PS/PBMA blends. The TEM micrographs also showed that the PS/PBMA blends are partially inhomogeneous on a scale of 50 nm, and only a single glass transition temperature was found by DMTA for the PS/PBMA blends containing more than 3.0 ml of (2-hydroxy) methacrylate /100 ml styrene.     

Apatite formation on poly(2-hydroxyethyl methacrylate)-silica hybrids prepared by sol-gel process

Hybrids of poly(2-hydroxyethyl methacrylate) (PHEMA), a polymer that has been employed in a wide variety of biomedical applications, and silica-gel, which exhibits a well-known bioactivity, were produced. The obtained hybrids were characterized and their in vitro ability to induce the formation of a calcium phosphate layer on the surface was evaluated. The surface area of hybrids decreased with increasing amounts of PHEMA so that hybrids with more than ~40% PHEMA are virtually non-porous. All hybrids induced the formation of a calcium phosphate layer on their surfaces when soaked into simulated body fluid. The induction time and the morphology of the apatite layer varied according to the polymer content.     

In-vitro study of the spontaneous calcification of PHEMA-based hydrogels in simulated body fluid

In-vitro calcification of poly(2-hydroxyethyl methacrylate) (PHEMA)-based hydrogels in simulated body fluid (SBF) under a steady/batch system without agitation or stirring the solutions has been investigated. It was noted that the formation of calcium phosphate (CaP) deposits primarily proceeded through spontaneous precipitation. The CaP deposits were found both on the surface and inside the hydrogels. It appears that the effect of chemical structure or reducing the relative number of oxygen atoms in the copolymers on the degree of calcification was only important at the early stage of calcification. The morphology of the CaP deposits was observed to be spherical aggregates with a thickness of the CaP layer less than 0.5 μ m. Additionally, the CaP deposits were found to be poorly crystalline or to have nano-size crystals, or to exist mostly as an amorphous phase. Characterization of the CaP phases in the deposits revealed that the deposits were comprised mainly of whitlockite [Ca₉MgH(PO₄)₇] type apatite and DCPD (CaHPO₄⋅2H₂O) as the precursors of hydroxyapatite [Ca₁₀(PO₄)₆(OH)₂]. The presence of carbonate in the deposits was also detected during the calcification of PHEMA based hydrogels in SBF solution.     

Effect of γ-irradiation on the structure of poly(ethyl acrylate-co-hydroxyethyl methacrylate) copolymer networks for biomedical applications

The effect of the sterilization process by γ-irradiation on the structure of poly(ethyl acrylate-co-hydroxyethyl methacrylate) copolymer networks, P(EA-co-HEMA) is studied for a broad dose range (7, 15, 25 and 50 kGy) and copolymer composition interval (0, 0.3, 0.5, 0.7 and 1 weight fraction of HEMA in the copolymer). γ-irradiation promotes chain scission in PHEMA homopolymer but induces new crosslinking points in PEA homopolymer. Both effects are present in the copolymers, with a net result that depends on composition. For copolymers with high HEMA fractions chain scission predominates, while, as the amount of EA in the copolymer increases, the situation changes and the net effect turns out to be an increase in the number of elastically active chains. Further, γ-irradiation strengthens the γ relaxation in PHEMA homopolymer, what suggest that the number of interchain hydrogen bonds decreases. FTIR spectroscopy reveals no oxidation as a consequence of the sterilization process.     

Dispersion of luminescent nanoparticles in different derivatives of poly(ethyl methacrylate)

Gd2O3:Tb(5%) nanoparticles were prepared via the polyol route and dispersed without any stabilizer in several ethyl methacrylate derivatives matrices such as poly(ethyl methacrylate), poly(2-methoxyethyl methacrylate) and poly(2-hydroxyethyl methacrylate) (PHEMA). Nanocomposites were obtained via free-radical polymerization of methacrylic monomers with ethylene glycol dimethacrylate as crosslinker and colloidal solution of Gd2O3:Tb(5%) nanoparticles. Best results are obtained with PHEMA in which the dispersed Gd2O3:Tb(5%) nanoparticles are spherical with a mean diameter of 15 nm, as measured by TEM. The obtained solid Gd2O3:Tb(5%)/PHEMA nanocomposites are highly transparent (in the visible spectral range) and exhibit characteristic photoluminescence of Tb3+ 5D4-7F(J) (J = 6-3), with 5D4-7F5 strong green emission at 536 nm upon UV excitation. The nanoparticles and nanocomposites have been well characterized by high-resolution transmission electron microscope (TEM), UV/Vis transmission spectra, photoluminescence excitation, and emission spectra.     

Broadband microwave Luneburg lens made of gradient index metamaterials

Luneburg lenses are able to form perfect focus that is free of aberration. Because of the varying refractive index throughout the lens, incoming electromagnetic waves can travel in a curved path and be guided to focus at the back of the lens. The implementation of Luneburg lenses is often difficult due to the challenges in creating a medium with varying refractive index using normal materials. This problem can be overcome with the use of gradient index metamaterials. We report a two dimensional Luneburg lens made of gradient index metamaterials. It consists of 17 concentric shells with etched patterns on a printed circuit board working in microwave X band frequency. The broad properties of the Luneburg lens are then discussed.     

Determination of refractive indices of biconvex lenses by use of a Michelson interferometer

Measurements of lens parameters such as focal length, radius of curvature, and refractive index are important. We describe a measurement method that utilizes a Michelson interferometer to determine parameters of thin, convex lenses. The real fringe system formed by a Michelson interferometer is used to determine the focal lengths and the radii of curvature of the lenses. The refractive index of the lens material is determined from the thin-lens formula. We were able to determine the refractive indices to an accuracy as great as 99.97%. A detailed theoretical and experimental analysis is given.     

Properties of flexible, transparent barium titanate nanoparticle/poly(2-hydroxyethyl methacrylate) hybrid

A transparent BaTiO₃ particle/poly(2-hydroxyethyl methacrylate) (PHEMA) hybrid was synthesized from a Ba–Ti double alkoxide modified with an organic ligand, and the refractive index and ferroelectric properties of the hybrid were studied. The transparent hybrid was flexible and could be shaped not only in the form of thin films on substrates but also in the form of flexible self-standing films. BaTiO₃ particles around 5 nm in diameter were dispersed uniformly in the polymer matrix. The refractive indexes of the hybrid films increased with decreasing wavelength and were dependent on the volume fractions of the BaTiO₃ and polymer phases. The hybrid film synthesized at a molar ratio of BaTiO₃:2-vinlyloxyethanol:H₂O:PHEMA = 1:8:30:5 gave the best result, with a refractive index of 1.55 at 589 nm and an Abbe number of 37.5. A transparent hybrid film on platinized silicone substrates exhibited a polarization–electric field hysteresis loop.     

Adhesion and morphology of fibroblastic cells cultured on different polymeric biomaterials

Cell adhesion is influenced by the physical and chemical characteristics of the materials used as substrate for cell culturing. In this work, we evaluated the influence of the morphological and chemical characteristics of different polymeric substrates on the adhesion and morphology of fibroblastic cells. Cell growth on poly (L-lactic acid) [PLLA] membranes and poly(2-hydroxy ethyl methacrylate) [polyHEMA], poly(2-hydroxy ethyl methacrylate)-cellulose acetate [polyHEMA-CA] and poly(2-hydroxy ethyl methacrylate)-poly(methyl methacrylate-co-acrylic acid) [polyHEMA-poly(MMA-co-AA)] hydrogels of different densities and pore diameters was examined. Cells adhered preferentially to more negativaly charged substrates, with polyHEMA hydrogels being more adhesive than the other substractes. The pores present in PLLA membranes did not interfere with adhesion, but the cells showed a distinctive morphology on each membrane.     

The study of adsorption characteristics Cu and Pb ions onto PHEMA and P(MMA-HEMA) surfaces from aqueous single solution

The adsorption characteristics of Cu²⁺ and Pb²⁺ ions onto poly2-hydroxyethyl methacrylate (PHEMA) and copolymer 2-hydroxyethyl methacrylate with monomer methyl methacrylate P(MMA-HEMA) adsorbent surfaces from aqueous single solution were investigated with respect to the changes in the pH of solution, adsorbent composition (changes in the weight percentage of MMA copolymerized with HEMA monomer), contact time and the temperature in the individual aqueous solutions. The linear correlation coefficients of Langmuir and Freundlich isotherms were obtained. The results revealed that the Langmuir isotherm fitted the experimental results better than the Freundlich isotherm. Using the Langmuir model equation, the monolayer adsorption capacity of PHEMA surface was found to be 0.840 and 3.037 mg/g for Cu²⁺ and Pb²⁺ ions and adsorption capacity of (PMMA-HEMA) was found to be 31.153 and 31.447 mg/g for Cu²⁺ and Pb²⁺ ions, respectively. Changes in the standard Gibbs free energy (ΔG⁰), standard enthalpy (ΔH⁰) and standard entropy (ΔS⁰) show that the adsorption of mentioned ions onto PHEMA and P(MMA-HEMA) are spontaneous and exothermic at 293–323 K.     

Analysis of the focal characteristics of cylindrical lenses made of anisotropically dielectric material based on rigorous electromagnetic theory

Abstract

The focal characteristics of refractive cylindrical lenses made of anisotropically dielectric material (uniaxial crystal) are analysed based on rigorous electromagnetic theory and the boundary element method. The performances of the lenses with different f numbers are appraised for both incident waves of the TE (transverse electric) and TM (transverse magnetic) polarizations. Numerical results show that the focal performance of this kind of lens for the TE polarization and the TM polarization of incident light wave is a difference, in particular, different focal lengths, owing to the anisotropy of the material. However, for the conventional isotropic lens, the focal features for both the TE and TM polarizations are the same. It is anticipated that this new kind of lens proposed for the first time may serve as a light switching device with high speed used in the micro-optical communication.     

Polymeric surface coatings for use as leather finishes—Part I. Studies on synthesis and characterisation of urethane acrylate oligomers

Synthesis and characterisation bynmr spectroscopy of oligomers derived from 2-hydroxy ethyl acrylate (hea) and 2-hydroxy propyl methacrylate (hpma) and 1,6-bexamethylene diisocyanate (hdi) are briefly discussed.     

Synthesis and Application of Hethacrylate Polyhers in the Forhulation of Hatrix Tablets

Abstract

Polymers were prepared by using two types of methacrylate monomers viz. hydrophobic monomers (methymethacrylate, butylmethacrylate) and hydrophilic monomers (2-hydroxy ethyl methacrylate, 2-hydroxy propyl methacrylate) using solution polymerisation method. Characterisation of the physico-chemical properties of the polymers was studied. The polymers were then evaluated as matrix formers for drugs selected on the basis of their aqueous solubility.     

Optical properties of polyethylene/styrene-co-methacrylate copolymers IPN-like networks: Effect of different methacrylate styrene co monomers on properties

Low-density Polyethylene (PE) were synthesized with poly[butyl methacrylate (B)-co-styrene (S)], poly(dodecyl methacrylate(D)-co-styrene] and poly(ethyl hexyl methacrylate (EH)-co-styrene] copolymers in order to obtain IPN-like networks. Different S/methacrylate copolymer molar ratios going from 0/100 up to 60/40, a molar percentage of 1.0% of 1,4-butanedioldimethacrylate (b) and 3 wt% of 2,5-dimethyl-2,5-di-(tert-butyl peroxy) hexane (Luperox 101) were used. The samples were analyzed at RT by WAXS, swelling in CCl₄ and mechanical tensile tests. Dynamic-mechanical tests and optical investigations were performed in a temperature range between RT and 180°C. All the IPN types showed optical reversible transitions (transparency-to opacity and vice versa) with varying temperature, due to a refractive index (RI) matching-mismatching of PE and copolymer networks. The copolymer chemical nature as well as its composition affected sensitively most of the analyzed properties.     

Retroreflector approximation of a generalized Eaton lens

We extended a previous study of the Eaton lens at specific refraction angles to the Eaton lens at any refraction angle. The refractive index of the Eaton lens is complicated and has no analytical form except at a few specific angles. We derived a more accessible form of the refractive index for any refraction angle with some accuracy using the retroreflector approximation. The finding of this study will be useful for a rapid estimation of the refractive index, and the the design of various Eaton lenses.     

Ophthalmic application of poly(HEMA)s containing nanoparticles and dimethylacrylamide

High functional ophthalmic lens materials, poly(HEMA-co-MMA)s were prepared by the copolymerization of HEMA, MMA, MA, EDGMA, and N,N-dimethylacrylamide in the presence of platinum nanoparticles with antimicrobial properties. The hydrophilic monomer N,N-dimethylacrylamide has excellent biocompatibility and oxygen transmissibility. The combination where platinum nanoparticles were added produced a colorless transparent lens. The water contents were in the range of 36.68-44.08% and the refractive index was measured to be in the range of 1.424-1.436. Meanwhile, the oxygen transmissibility ranged from 11.13 x 10(-11) to 17.63 x 10(-11) (cm2/sec) (mlO2/ml x mm Hg) increased with increasing the addition ratio of N,N-dimethylacrylamide. The physical properties measurements of the produced polymers showed that the nanoparticles did not show significant effect on the water content and refractive index of the hydrogel contact lens, but the materials effected to reduce oxygen permeability to a certain extent. The copolymers have excellent oxygen permeability, indicating that the material can be used to fabricate hydrogel contact lenses with high oxygen transmissibility.     

Characterization of polymer films using a slow positron beam

Polymer structures have been investigated using positron annihilation lifetime spectroscopy (PALS) with a slow positron beam as well as a conventional radioactive source (²²Na). The properties of the free volume holes near the polymer surface were studied as a function of the positron implantation energy. The longest lifetime was associated with ortho-positronium (o-Ps) annihilation in the free volume holes. In polytetrafluoroethylene film, the lifetime of o-Ps was observed to decrease with increasing positron implantation depth, and a significant change in the o-Ps lifetime was found at a short distance (about 10 nm) from the surface, while its intensity increased. This result implies that near the polymer surface the free volume holes become larger that in the bulk. The effect of temperature on the polymer sub-surface layers was also studied. For high molecular weight polystyrene, the glass transition temperature for the sub-surface was lower than that for the bulk and thermal expansion coefficient of the sub-surface layers was found to be larger than the bulk value. Electronic Publication     

Fast response varifocal lenses using KTa(1-x)Nb(x)O3 crystals and a simulation method with electrostrictive calculations

We fabricated cylindrical varifocal lenses with fast responses by using the strong Kerr effect of KTa(1-x)Nb(x)O(3) (KTN) single crystals. We observed focus shifts of up to 87 mm with the assistance of a 250 mm focal length lens, which corresponds to a focus shift from infinity to 720 mm by the KTN lens itself. The response time was as fast as 1 μs. We also present a simulation method for calculating refractive index distributions in KTN single crystals, which is essential when designing the lens. The method is characterized by the strain contribution, which has not conventionally been typical of electro-optic simulations. We used this method to explain the refractive index modulations that are characteristic of the varifocal lenses.     

Poly(glycidyl methacrylate) beads embedded cryogels for pseudo-specific affinity depletion of albumin and immunoglobulin G

Depletion of high abundant proteins like albumin and immunoglobulin G (IgG) can be beneficial in the analysis of serum proteins. For this purpose, Cibacron Blue F3GA and iminodiacetic acid (IDA)-Cu²⁺ containing poly(glycidyl methacrylate) (PGMA) beads (1.6 µm in diameter) were embedded into the poly(hydroxyethyl methacrylate) (PHEMA) cryogel. The PGMA beads were prepared by dispersion polymerization. The PGMA beads were modified with Cibacron Blue F3GA and iminodiacetic acid (IDA)-Cu²⁺ for simultaneous albumin and IgG depletion, respectively. The PHEMA cryogel was synthesized by free radical polymerization in the presence of the modified PGMA beads. The PHEMA and PHEMA/PGMA composite cryogels were characterized by swelling measurements and scanning electron microscopy (SEM). Protein depletion studies were carried out in a continuous experimental set-up in a stacked column. Albumin adsorption capacity of the PGMA-Cibacron Blue F3GA beads embedded PHEMA cryogel (PHEMA/PGMA-Cibacron Blue F3GA) was 342 mg/g and IgG adsorption capacity of the PGMA-IDA-Cu²⁺ beads embedded PHEMA cryogel (PHEMA/PGMA-IDA-Cu²⁺) was 257 mg/g. The composite cryogels depleted albumin and IgG from human serum with 89.4% and 93.6% efficiency, respectively. High desorption values (over 90% for both modified cryogels) were achieved with 0.05 M phosphate buffer containing1.0 M NaCl.