压电传感器在线监测蛋白质在自组装膜上的吸附

在压电石英晶体传感器的金电极表面化学修饰烷基硫醇（ＨＳ（ＣＨ２）１５ＣＨ３）的自组装单层膜（ＳＡＭ）,并利用该传感器在线监测纤维蛋白原在ＳＡＭ表面的吸附过程。该方法给出有关蛋白质吸附的动力学、可逆性,吸附等温线等方面的信息。     

压电传感器在环境监测中的应用

简要介绍了压电石英晶体微天平（ＱＣＭ）及表现声波（ＳＡＷ）压电传感器的基本原理，从ＱＣＭ化学传感器毒气检测、ＱＣＭ化学传感器液相检测、ＳＡＷ化学传感器分析、压电生物传感器物质分析、压电生物传感器液相分析、压电传感器陈列、非质量效应压电传感器等方面介绍了近年来压电传感器在环境监测领域的研究进展，并展望了压电传感顺在环境监测中的应用前景。     

一种快速响应的压电晶体生物亲和传感器

在６ＭＨｚ的压电晶振ＱＣＭ（ｑｕａｒｔｚｃｒｙｓｔａｌｍｉｃｒｏｂａｌａｎｃｅ）金电极表面采用蛋白质Ａ－金的方法固定生物敏感膜，利用ＱＣＭ单面测试技术和连续流动自动分析系统全面测试此膜与人体免疫球蛋白Ｇ（ＩｇＧ）之间的生物亲和反应，从而研究快速响应的压电晶体生物亲和传感器，停止流动注测量时结果为：在１－２ｍｉｎ内亲和响应时间而急剧增大，随后趋于缓慢，对１０７μｇ／ｍｌ人体ＩｇＧ三次响应的标准偏差及     

毛果芸香碱（PCC）液相压电传感器

本文应用压电沉淀吸附法（ＰＰＡＡ）开展了对毛果芸香碱的测定。在柠檬酸缓冲液（ＣＢＳ）中，用四苯硼钠（ＴＰＢ）与盐酸毛果芸香碱反应生成稳定的胶体溶液，胶体颗粒吸附于石英晶体表面，使石英晶体的谐振频率发生改变（△Ｆ）。考察了ＣＢＳ浓度及ｐＨ值、ＴＰＢ浓度和温度等实验条件对△Ｆ的影响，测定了压电传感器对毛果芸香碱的响应特性。结果表明，盐酸毛果芸香碱在０．０３４－０．７５８ｍｍｏｌ／Ｌ范围，△Ｆ与毛果芸香     

自组装纳米金内毒素压电传感器的研究

利用纳米金颗粒自组装于金片表面上,用于固定多粘菌素B(PMB),研制了一种内毒素压电传感器。先在石英晶体电极表面自组装1,6—己二硫醇,再通过纳米金与巯基的共价键合作用,在巯基自组装膜的另一端的巯基表面形成一均匀的纳米金单层膜,实现PMB在传感器表面的固定。实验探讨了影响纳米金自组装和PMB固定等主要实验参数和条件;考核了采用此固定化方法传感器的响应性能。结果表明:与单纯采用自组装方法比,传感器在灵敏度和分辨力方面均有较大的改善。     

如何求解隐式辛格式

如何求解隐式辛格式李旺尧（中国科学院计算中心）一、前言ＨＯＷＴＯＳＯＬＶＥＩＭＰＬＩＣＩＴＳＹＭＰＬＥＣＴＩＣＳＣＨＥＭＥＳ￥ＬｉＷａｎｇｙａｏ（ＣｏｍｐｕｔｅｒＣｅｎｔｅｒ，ＡｃａｄｅｍｉａＳｉｎｉｃａ）Ａｂｓｔｒａｃｔ：Ｉｔｉｓｓｈｏｗｎｔｈａｔ...     

三维有限元自动网格生成

三维有限元自动网格生成李玉成（中国科学院计算中心）向田康之（日本富士通ＢＳＣ）ＡＵＴＯＭＡＴＩＣＴＨＲＥＥ－ＤＩＭＥＮＳＩＯＮＡＬＦＩＮＩＴＥＥＬＥＭＥＮＴＭＥＳＨＧＥＮＥＲＡＴＩＯＮ￥ＬｉＹｕｃｈｅｎｇ（ＣｏｍｐｕｔｉｎｇＣｅｎｔｅｒ，Ａｃａｄｅｍ...     

双曲守恒律的拟单调二阶格式

双曲守恒律的拟单调二阶格式胡长青（中国科学院计算中心）ＳＥＣＯＮＤ－ＯＲＤＥＲＱＵＡＳＩＭＯＮＯＴＯＮＥＳＣＨＥＭＥＳＦＯＲＣＯＮＳＥＲＶＡＴＩＯＮＬＡＷＳ￥ＨｕＣｈａｎｇ－ｑｉｎｇ（ＣｏｍｐｕｔｉｎｇＣｅｎｔｅｒ，ＡｃａｄｅｍｉａＳｉｎｉｃａ）Ａｂ...     

粘性项参与构造的隐式矢通量分裂格式及其数值模拟

粘性项参与构造的隐式矢通量分裂格式及其数值模拟刘仪，曹琦，刘斌（西安交通大学涡轮教研室）ＩＭＰＬＩＣＩＴＦＬＵＸＶＥＣＴＯＲＳＰＬＩＴＴＩＮＧＳＣＨＥＭＥＳＷＩＴＨＶＩＳＣＯＵＳＡＮＤＮＵＭＥＲＩＣＡＬＳＩＭＵＬＡＴＩＯＮ￥ＬｉｕＹｉ；ＣａｏＱｉ；Ｌ...     

统计数据凑整问题的网络流算法

统计数据凑整问题的网络流算法金大勇，杨承恩（长沙铁道学院）ＮＥＴＷＯＲＫＡＬＧＯＲＩＴＨＭＳＦＯＲＴＨＥＤＡＴＡＲＯＵＮＤＩＮＧＰＲＯＢＬＥＭ￥ＪｉｎＤａ－ｙｏｎｇ；ＹａｎｇＣｈｅｎｇ－ｅｎ（ＣｈａｎｇｓｈａＲａｉｌｗａｙＩｎｓｔｉｔｕｔｅ）Ａｂｓｔ...     

Electrochemical copper (II) sensor based on self-assembled 4-amino-6-hydroxy-2-mercaptopyrimidine monohydrate

A 4-amino-6-hydroxy-2-mercaptopyrimidine monohydrate (AHMP)-based self-assembled monolayer (SAM) was formed on the gold electrode surface. Ellipsometric measurements evidenced the SAM formation on the gold electrode surface. The structural integrity of the modified gold electrode was also characterized by insulating properties of the SAM that were detected by cyclic voltammetry. The results of cyclic voltammetry showed that the SAM, which was formed by assembly of AHMP, was stable but did not completely block the redox-activity of ferrocene and K₃[Fe(CN)₆]/K₄[Fe(CN)₆]. In contrast completely blocked redox-activity was observed after the treatment of AHMP-based SAM with saturated solution of 4-formylphenylboronic acid in 1,4-dioxan. The modified electrodes exhibited a selective response towards Cu(II) ions in the presence of some interfering ions such as Cd(II), Co(II), Fe(II), Ni(II) and Pb(II). This study is the first scientific report on the application of AHMP-modified electrode as a selective Cu(II) sensor in the presence of some interfering cations.     

环糊精含硫衍生物自组装成膜动力学研究 􀀁 􀀂

用石英晶体微天平（QCM）在线监测了β－环糊精含硫衍生物（β－CDd）在金电极上自组装成膜过程。探讨了温度、浓度对成膜过程及溶液pH值对膜稳定性的影响,给出了有关动力学信息。结果表明,成膜动力学符合Langmuir吸附速率方程。     

Simulation studies on structural and thermal properties of alkane thiol capped gold nanoparticles

The structural and thermal properties of the passivated gold nanoparticles were explored employing molecular dynamics simulation for the different surface coverage densities of the self-assembled monolayer (SAM) of alkane thiol. The structural properties of the monolayer protected gold nanoparticles such us overall shape, organization and conformation of the capping alkane thiol chains were found to be influenced by the capping density. The structural order of the thiol capped gold nanoparticles enhances with the increase in the surface coverage density. The specific heat capacity of the alkane thiol capped gold nanoparticles was found to increase linearly with the thiol coverage density. This may be attributed to the enhancement in the lattice vibrational energy. The present simulation results suggest, that the structural and thermal properties of the alkane thiol capped gold nanoparticles may be modified by the suitable selection of the SAM coverage density.     

Development of a molecular imprinting thick film electrochemical sensor for cholesterol detection

A combined molecular imprinting and thick film electrochemical sensor for cholesterol concentration detection had been developed. The ferro-ferric cyanide coupled redox reaction was used as the means to quantify the cholesterol presented in the test medium. This electrochemical sensor employed a modified gold working electrode, a platinum counter electrode and an Ag/AgCl reference electrode. The alkanethiol was used to form the self-assembled monolayer (SAM) on the gold working electrode. The SAM was then used with the cholesterol as the template forming the molecular imprinting layer. This sensor prototype could detect cholesterol concentrations between 66 and 700 nM and only a 1 μL of the sample volume was required.     

基于PANI/PdO复合薄膜的压电甲烷传感器

研究了一种基于压电原理的甲烷传感器。运用化学氧化聚合法和层层自组装法制备了对甲烷气体敏感的PANI/PdO复合薄膜,通过溅射工艺将薄膜生成在压电材料上,利用敏感薄膜对甲烷的吸附改变晶振频率,从而检测出甲烷气体的含量。实验表明:压电甲烷传感器具有较好的选择性,在0%~2%的甲烷体积分数范围内具有较好的线性输出。     

基于金纳米颗粒免疫凝集的压电传感技术快速检测人血清免疫球蛋白IgG

发展了一种利用金纳米颗粒免疫凝集的压电传感技术用于人血清免疫球蛋白IgG的简单、快速、高灵敏检测.以金纳米颗粒替代传统胶乳标记羊抗人IgG诊断血清(抗IgG),利用石英晶体微天平(QCM)直接灵敏响虚因金纳米颗粒免疫凝集而引起溶液的非质量参数(密度、粘度等)的变化.考察了pH值、离子强度和抗IgG-金纳米颗粒浓度对免疫凝集反应的影响,并进行了质控实验.结果表明,该传感技术毋需固定活性组分,可快速榆测浓度下限0.38μg/mL的免疫球蛋白IgC.定量能力与经典ELISA法相接近,可基本满足临床疾病诊断的生化检测要求.     

压电式免疫传感器检测小鼠IgG气溶胶

为优化压电式免疫传感器用于生物大分子气溶胶的检测效果,采用循环伏安法在石英晶体金电极上先聚合一层聚苯胺膜,然后,聚合一层聚间苯三酚膜,构建了双层聚合物膜,用于固定羊抗小鼠IgG抗体。配合超声雾化法产生生物大分子气溶胶,研制了一种直接气相检测小鼠IgG抗体的谐振式免疫传感器。结果表明:该传感器对小鼠IgG的响应快,检测时间为3m in;在0.42~4.8 g.L-1范围内,具有较好的线性关系;稳定性高,经固定的抗体可以保持活性60 d以上。     

Mapping hydrothermal alteration minerals using high-resolution AVIRIS-NG hyperspectral data in the Hutti-Maski gold deposit area,India

ABSTRACT

The present study exploits high-resolution hyperspectral imagery acquired by the Airborne Visible/Infrared Imaging Spectrometer-Next Generation (AVIRIS-NG) sensor from the Hutti-Maski gold deposit area, India, to map hydrothermal alteration minerals. The study area is a volcanic-dominated late Archean greenstone belt that hosts major gold mineralization in the Eastern Dharwar Craton of southern India. The study encompasses pre-processing, spectral and spatial image reduction using Minimum Noise Fraction (MNF) and Fast Pixel Purity Index (FPPI), followed by endmember extraction using n-dimensional visualizer and the United States Geological Survey (USGS) mineral spectral library. Image derived endmembers such as goethite, chlorite, chlorite at the mine site (chlorite mixed with mined materials), kaolinite, and muscovite were subsequently used in spectral mapping methods such as Spectral Angle Mapper (SAM), Spectral Information Divergence (SID) and its hybrid, i.e. SIDSAM_tan. Spectral similarity matrix of the target and non-target-based method has been proposed to find the possible optimum threshold needed to obtain mineral map using spectral mapping methods. Relative Spectral Discrimination Power (RSDPW) and Confusion Matrix (CM) have been used to evaluate the performance of SAM, SID, and SIDSAM_tan. The RSDPW and CM illustrate that the SIDSAM_tan benefits from the unique characteristics of SAM and SID to achieve better discrimination capability. The Overall Accuracy (OA) and kappa coefficient (?) of SAM, SID, and SIDSAM_tan were computed using 900 random validation points and obtained 90% (OA) and 0.88 (?), 91.4% and 0.90, and 94.4% and 0.93, respectively. Obtained mineral map demonstrates that the northern portion of the area mainly consists of muscovite whereas the southern part is marked by chlorite, goethite, muscovite and kaolinite, indicating the propylitic alteration. Most of these minerals are associated with altered metavolcanic rocks and migmatite.