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1.
Responses of dairy cows in early lactation to bovine somatotropin and ruminally inert fat 总被引:1,自引:0,他引:1
Bovine somatotropin (0 or 41.2 mg/d bST) and calcium salts of long-chain fatty acids (0 or .77 kg/d Ca-LCFA) were administered to 16 Holstein cows in early lactation. Cows remained on 0 or 41.2 mg/d bST for the entire 10 wk and received 0 or .77 kg/d Ca-LCFA in one of two 5-wk periods. Production data were recorded daily, milk fatty acids, and blood metabolites were determined once each period. Treatments did not affect feed intake. Fat-corrected milk (kg/d) and percentage of milk fat for cows receiving no supplementation, fatty acids alone, bST alone, and fatty acids and bST together were 33.8, 3.2; 33.5, 3.1; 37.4, 3.4; and 40.8, 3.5. Milk fatty acids below C16 were reduced with either bST or dietary fatty acids; C16 fatty acids were lower with bST but higher with dietary fatty acids; C18:0 fatty acids were reduced with dietary fatty acids; and C18:1 fatty acids were higher with either bST or dietary fatty acids. Blood acetoacetate concentrations were higher with both bST and dietary fatty acids, beta-hydroxybutyrate was not different, and FFA and insulin concentrations increased with bST. In this experiment, the energy supplied by Ca-LCFA acids enhanced the lactogenic effect of bST. 相似文献
2.
Tarazón-Herrera M Huber JT Santos J Mena H Nusso L Nussio C 《Journal of dairy science》1999,82(11):2352-2357
Thirty-two Holstein cows (8 per treatment) averaging 195 d in milk were assigned to 70 d of treatment on the basis of production during a 14-d pretreatment period, which was used for covariate analysis. The experiment was a randomized block design with a 2 x 2 factorial arrangement of treatments. Factors were normal shade or shade plus evaporative cooling with pressurized spray, plus with or without the administration of bovine somatotropin (bST). Cows receiving bST were injected with 500 mg of bST every 14 d. All cows were fed the same total mixed rations twice daily at approximately 10% in excess of appetite, and water was offered free choice. There were no interactions between bST and the cooling system for any of the variables measured. Milk yield was increased by bST and tended to be greater for cooled cows. Fat percentages were increased by bST, and yields of fat, protein, and 3.5% fat-corrected milk, and the efficiency of conversion of dry matter to milk, whereas evaporative cooling increased body weights and protein yields, but decreased SNF and milk protein percentages. Rectal temperatures and respiration rates also were lower for cooled cows. And, bST increased nonesterified fatty acids in blood serum, suggesting that a part of the energy for increased milk production came from mobilization of body fat. Administration of bST effectively improved performance of cows under hot summer conditions whether evaporatively cooled or not. 相似文献
3.
Lactational responses of dairy cows fed unsaturated dietary fat and receiving bovine somatotropin. 总被引:1,自引:0,他引:1
Feeding unsaturated dietary fat to lactating dairy cows receiving bST may effectively alter the fatty acid composition of milk fat. This was tested using 16 Holstein cows assigned to one of four treatments during midlactation. Treatments were control, control diet with 15.5 mg of bST/d per cow, dietary fat from sunflower seeds and bST, or dietary fat from safflower seeds and bST. Diets were formulated to contain 19% CP and contained 25% corn silage, 25% alfalfa hay, and 50% concentrate mix on a DM basis. Milk yield was not significantly higher when bST was administered and increased with added fat diets (29.5, 32.7, 40.0, and 34.1 kg/d for the control, control with bST, sunflower seed with bST, and safflower seed with bST treatments, respectively). Percentage of milk fat was similar for all treatments. Concentrations of long-chain and unsaturated fatty acids in milk were increased slightly by bST and substantially with added fat. Milk protein percentages were not influenced by bST but were reduced by approximately .2 unit with added fat. Added unsaturated dietary fat coupled with bST increased milk yield and produced a greater concentration of unsaturated fatty acids in milk. 相似文献
4.
Effects of bovine somatotropin on dry matter intake, milk yield and body temperature in Holstein and Jersey cows during heat stress 总被引:1,自引:0,他引:1
J W West B G Mullinix J C Johnson K A Ash V N Taylor 《Journal of dairy science》1990,73(10):2896-2906
Thirty-one lactating Holstein and Jersey cows were used to determine the effect of daily injections of 0 or 20 mg of recombinant bST in hot, humid weather. The comparison period lasted 80 d, from mid-June through August. The maximum and minimum ambient temperature and relative humidity averaged 34.6 and 22.2 degrees C and 100 and 59.8%, respectively. Body temperatures of somatotropin-treated Holsteins were elevated over controls by .2 and .3 degrees C at the a.m. and p.m. milkings, respectively, whereas corresponding treatment effects for Jerseys were .5 and .6 degrees C, thus demonstrating a breed by treatment interaction. The response of milk and FCM yields and apparent efficiency of production to somatotropin administration depended on the level of production prior to treatment. Cows at low pretreatment production increased milk and FCM yields to a greater degree than did cows at higher production. A breed by treatment interaction showed that Holsteins increased milk and FCM yields more than Jerseys upon administration of somatotropin. Intake of DM was not affected by treatment. Cows administered bST lost BW and condition score. Greater heat stress was associated with the higher milk production of cows administered bST. 相似文献
5.
Composition and flavor of milk and butter were evaluated from cows divided into four treatments including a control, control with bST, added dietary fat from sunflower seeds with bST, or added dietary fat from safflower seeds with bST. Feeding added unsaturated dietary fat resulted in lower concentrations of short-and medium-chain and higher concentrations of long-chain fatty acids in milk fat and butter. Milk fat unsaturated fatty acid concentrations were 25.0, 28.4, 39.6, and 37.9%, and butter unsaturated fatty acid concentrations were 23.0, 26.9, 37.8, and 36.2% for control, control with bST, sunflower seeds with bST, and safflower seeds with bST, respectively. Sensory evaluations indicated that butters from the bST with sunflower seed and bST with safflower seed treatments were equal or superior in flavor to the control butter. Milk from cows receiving bST or fed added unsaturated dietary fat and receiving bST was no more susceptible to oxidized off-flavors than control milk. Butters from sunflower seed and safflower seed treatments with bST contained higher concentrations of unsaturated fatty acids, were softer at 4 and 20 degrees C, and possessed acceptable flavor and processing characteristics compared with butters from control and control with bST. 相似文献
6.
Eight lactating Holstein dairy cows (80 d in milk) were used to examine the effects of exogenous bovine somatotropin (bST) on hepatic contents of mRNA encoding pyruvate carboxylase (PC), phosphoenolpyruvate carboxykinase (PEPCK), and microsomal triglyceride transfer protein (MTP). Concentrations of bST in plasma were higher and milk production increased 20% in bST-treated cows. Liver samples from cows treated with bST had significantly higher total lipid contents than those from control cows. Although there were small numerical tendencies, neither triglyceride concentrations in liver nor nonesterified fatty acids (NEFA), beta-hydroxybutyrate (BHBA), or glucose in plasma differed significantly between bST-treated and control cows. Short-term bST treatment had no detectable effects on contents of PC, PEPCK, and MTP mRNA in the liver. In summary, exogenous bST stimulation of milk production is not mediated through enhanced liver gluconeogenesis, but may involve partitioning of glucose and fatty acids for preferential use by the mammary gland. 相似文献
7.
J Skarda E Markalous J Slaba P Krejcí O Skardová J Zedník 《The Journal of dairy research》1992,59(4):499-506
Milk production of dairy cows in 14 herds was increased by 3.8-32.1% by the administration of recombinant methionyl bovine somatotropin (bST) in a sustained-release vehicle at 14 d intervals at 40-94 d post partum. A greater response in multiparous than in primiparous cows was found in cows turned out to graze spring pasture. Administration of recombinant bST resulted in elevated plasma bST during the first 9 d after injection. Clinical characteristics such as respiration, heart rate and body temperature were unaffected by bST treatment, as were blood erythrocyte and leucocyte counts, haemoglobin concentrations and haematocrit values. Plasma levels of glucose, free fatty acids, urea and P, and serum alanine aminotransferase and aspartate aminotransferase were not affected by bST treatment, and acetone was not detected. No adverse effects of bST on general health, infection status of mammary glands, mastitis incidence and reproduction were found. 相似文献
8.
J M Lynch D M Barbano D E Bauman G F Hartnell M A Nemeth 《Journal of dairy science》1992,75(7):1794-1809
Nine Holstein cows were injected bi-weekly with a prolonged-release formulation of N-methionyl bST, and 9 cows were injected with excipient. Intramuscular injections began at 60 +/- 3 d postpartum and continued at 14-d intervals for the full lactation. Administration of bST increased production of milk, total fat, and all milk fat components measured. Average fatty acid composition of milk fat was not influenced by bST treatment. Stage of lactation had a large influence on production and percentage of individual fatty acids in milk fat from both bST-treated and control cows. The stage of lactation impact on the fatty acid composition of milk fat reflected changes in the relative contributions of body fat mobilization and de novo synthesis of milk fat components in response to changes in energy balance. Initiation of bST treatment caused some transient changes in milk fatty acid composition that were related to energy balance. These changes were small compared with the normal changes because of stage of lactation in all cows. Phospholipid and cholesterol content of milk also changed with stage of lactation but were not influenced by bST treatment. Melting properties of milk fat were influenced greatly by stage of lactation. Bovine somatotropin did not cause any changes in composition or physical properties of milk fat that were outside the range of normal variation. 相似文献
9.
R J Annexstad D E Otterby J G Linn W P Hansen C G Soderholm J E Wheaton R G Eggert 《Journal of dairy science》1990,73(9):2423-2436
Twenty-five Holstein cows were used to examine effects of recombinant bST administration for a second successive lactation on milk yield and composition, BW change, body condition, and health. Treatments were 0 (physiological saline), 10.3, 20.6, and 33 mg bST/d (8, 8, 7, and 3 cows per treatment, respectively). Saline and bST were given daily as subcutaneous injections beginning 4 to 5 wk postpartum and continuing for 38 wk. Somatotropin increased 3.5% FCM yield linearly from 8 to 36% over controls (control FCM was 30.1 kg/d). Milk composition was not affected by bST except that milk from cows given the 10.3-mg dosage had slightly higher Ca and P contents than did milk from cows receiving 0 or 20.6 mg. Cows receiving bST were 9 to 30% more efficient than controls in converting feed to milk. Body weight gain was unaffected by treatment. Average condition score was unchanged for control cows during the first 84 d following initiation of treatment, but declined in cows given bST. Thereafter, condition score increased in a similar manner for all groups. No treatment-related patterns were found in incidence of mastitis, feet and leg problems, ketosis, or milk fever. Blood hormone, chemistry, and hematology revealed no effects of bST treatment other than to raise plasma bST concentrations. Under conditions of this experiment, use of bST during a second consecutive lactation did not change the normal physiology or productive capacity of lactating cows. 相似文献
10.
M. Carriquiry W.J. Weber G.C. Lamb L.H. Baumgard B.A. Crooker 《Journal of dairy science》2009,92(10):4865-4875
Multiparous cows (n = 59) were blocked by expected calving date and previous milk yield and assigned randomly to treatments to determine effects of bovine somatotropin (bST; Posilac, Monsanto Animal Agricultural Group, St. Louis, MO) and source of dietary fat on milk fatty acid composition during the first 140 d in milk. Diets were provided from calving and included whole, high-oil sunflower seeds (SS; 10% of dietary dry matter; n-6/n-3 ratio of 4.6) as a source of linoleic acid or a mixture of Alifet-High Energy and Alifet-Repro (AF; Alifet USA, Cincinnati, OH; 3.5 and 1.5% of dietary dry matter, respectively; n-6/n-3 ratio of 2.6) as a source of protected n-3 fatty acids (15.7% 18:3, 1.3% 20:5, and 1.3% 22:6). Treatments were derived from a 2 × 2 combination of supplemental fat source (SS, AF) and with 0 (SSN, AFN) or 500 (SSY, AFY) mg of bST administered every 10 d from 12 to 70 d in milk and at 14-d intervals thereafter. Milk fatty acid composition was determined in samples collected from 32 cows (8 complete blocks) during wk 2, 8, and 20 of lactation. Data were analyzed as repeated measures using mixed model procedures to determine the effects of diet, bST, week of lactation, and their interactions. Proportions of 18:3 (4.02 vs. 3.59 ± 0.16%), 20:5 (0.52 vs. 0.41 ± 0.02%), and 22:6 (0.11 vs. 0.02 ± 0.02%) were greater and the n-6/n-3 fatty acid ratio (7.40 vs. 8.80 ± 0.30) was reduced in milk from cows fed AF compared with SS. Proportions of de novo-synthesized fatty acids increased and preformed fatty acids decreased as lactation progressed, but bST administration delayed this shift in origin of milk fatty acids. Transfer efficiency of 18:3, 20:5, and 22:6 from AF to milk fat averaged 36.2, 4.9, and 5.2%, respectively. These efficiencies increased as lactation progressed, but were delayed by bST. Apparent mammary Δ9-desaturase activity and milk conjugated linoleic acid (cis-9, trans-11 conjugated linoleic acid) content increased through the first 8 wk of lactation. Based on the product-to-substrate ratio of 14:1/14:0 fatty acids in milk, there was an interaction of diet and bST because bST decreased apparent Δ9-desaturase activity in SSY cows but increased it in AFY cows (0.10, 0.09, 0.08, and 0.09 ± 0.01 for SSN, SSY, AFN, and AFY, respectively). Feeding Alifet-Repro increased n-3 fatty acids in milk and bST prolonged the partitioning of dietary fatty acids into milk fat. 相似文献
11.
Responses of Holstein cows to a low dose of somatotropin (bST) prepartum and postpartum 总被引:3,自引:0,他引:3
Objectives were to evaluate the effects of a low dose of bovine somatotropin (bST) injected prepartum and postpartum on body condition score (BCS), body weight (BW), and milk yield (MY) in cows as well as somatotropin insulin, insulin-like growth factor-I (IGF-I), glucose, and nonesterified fatty acids (NEFA) in plasma. Holstein cows nearing second or later parities were assigned randomly to control (CON = 98) or bST-treated (TRT = 95) groups. Biweekly injections of bST began 21 +/- 3 d before expected calving and continued through 42 d postpartum (CON vs. TRT; 0 vs. 10.2 mg of bST/ d). From 42 to 100 d postpartum, no cows received bST. During yr 1, somatotropin, IGF-I, insulin, NEFA, and glucose were measured in plasma samples from 82 cows. During yr 2, effects of bST on BCS and BW of 111 cows were evaluated, but no blood samples were collected. Milk yields through 100 d of all 193 cows were analyzed. Prepartum treatment with bST resulted in greater prepartum plasma concentrations of somatotropin, insulin, and numerically greater NEFA but did not affect glucose or IGF-I. Postpartum bST increased mean plasma concentrations of somatotropin and NEFA, but not INS, IGF-I, or glucose. Mean BCS of cows did not differ prepartum, around parturition, or postpartum. Although mean BW did not differ prepartum or around calving, cows receiving bST maintained greater BW postpartum. Cows receiving bST tended to have higher MY (6.6%) in the first 60 d of lactation, but differences did not persist through 100 d, including approximately 40 d when no cows received bST. Number of cows that were culled due to health (CON = 3 vs. TRT = 2) or died (CON = 3 vs. TRT = 1) were not affected by treatment. Low doses of bST in the transition period resulted in higher postpartum BW, quicker recovery of body condition during lactation, and significantly more milk during treatment. 相似文献
12.
A V Capuco D L Wood T H Elsasser S Kahl R A Erdman C P Van Tassell A Lefcourt L S Piperova 《Journal of dairy science》2001,84(11):2430-2439
Twelve Holsteins in first lactation were used to investigate the relationship between energy balance and effects of bovine somatotropin (bST) on thyroid hormone metabolism and cytokine concentrations in serum. Six cows were fed for ad libitum intake and six cows were feed restricted to induce negative energy balance during two treatment periods of 6 d. During treatment periods, cows were administered vehicle or 40 mg of bST/d according to a crossover design. Between treatment periods was a 15-d recovery period, during which all cows were fed ad libitum. Cows that were fed ad libitum remained in positive energy balance during control and bST treatments, whereas cows that were fed for restricted intake were in negative energy balance during control and bST treatment periods. In both dietary groups, bST decreased energy balance. Milk production and the fat percentage of milk increased during bST treatment in both dietary groups. Fat-corrected milk yield was increased 13% by bST treatment. Serum concentrations of IGF-I did not differ between dietary groups but were greater during bST than control periods. Serum thyroxine concentration was decreased by bST treatment. Serum triiodothyronine and reverse-triiodothyronine were not altered by hormone treatment, but circulating concentrations of thyroid hormones were apparently reduced by dietary restriction. Neither hepatic nor mammary thyroxine 5'-deiodinase was affected by bST treatment. Plasma concentration of tumor necrosis factor-alpha, a potential regulator of thyroxine 5'-deiodinase, was not affected by bST treatment. Short-term treatment with bST did not influence thyroid hormone metabolism in lactating cows in positive or negative energy balance. 相似文献
13.
The effect of fat and bovine somatotropin (bST) on preovulatory follicular hormones and lipids was evaluated by feeding cows for 150 d from parturition a control diet, a control diet plus 0.55 kg/d of calcium soaps of fatty acids, or a control diet with 500 mg of bST injected every 14 d. Fourteen days after a synchronized or natural estrus, cows were injected with a PGF2 alpha analogue; 48 h later, follicular fluid from all ovarian follicles > 8 mm was aspirated. Cows fed fat or injected with bST produced more milk and milk solids than did control cows, and cows on the bST treatment lost more body condition after calving than did cows on the other treatments. Both treatments changed the proportion of estradiol-active follicles (> 400 ng of estradiol/ml of follicular fluid) and the correlation between follicular fluid estradiol concentration and the total number large follicles per cow. In follicles aspirated between 60 and 90 DIM the percentage of estradiol-active follicles was 67, 40, and 0 for cows on the control, calcium soaps of fatty acids, and bST treatments, respectively. After 90 DIM, no differences existed between treatments in the percentage of estradiol-active follicles. Estradiol concentration in follicular fluid was correlated with DIM at follicle aspiration (r = 0.51). The proportion of oleic acid in free fatty acids in plasma at 50 DIM was lower in control cows and was lower in follicular fluid of estradiol-active follicles. Both calcium soaps of fatty acids and bST had a considerable effect on follicular development and activity and the composition of fatty acids in follicles. 相似文献
14.
We allocated 39 high-yielding individually fed cows to three treatments: control, calcium soaps of fatty acids (CSFA) fed at 2.2% dry matter, and 500 mg of Zn-sometribove (bST) injected every 14 d from 10 to 150 d in milk (DIM). Production of fat corrected milk was increased by 3.0 kg/d in the CSFA group and by 5.4 kg/d in the bST group. Energy balance was negative during the first 28 to 34 DIM in control and CSFA cows and during 59 DIM in bST-treated cows; minimum body weight, minimum body condition score, and DMI peak were reached 25-28 d later in the bST group. Dry matter intake (DMI) was significantly increased by bST, and during the first 3 wk of treatment the increase in DMI of the bST cows was 46% more than that of the controls. DMI was significantly correlated throughout the experimental periods with calculated energy expenditure in the control and CSFA groups, but only during 54 DIM in the bST group. Furthermore, commencement of the DMI decrease was correlated with the beginning of the decrease in milk production. Gross feed efficiency was significantly higher in the bST group than in the other groups. We concluded that treating high-yielding cows with bST early in lactation increased milk production at the expense of an extensive period of negative energy balance and body weight and body condition decreases despite an increase in DMI after bST treatment. 相似文献
15.
Settivari RS Spain JN Ellersieck MR Byatt JC Collier RJ Spiers DE 《Journal of dairy science》2007,90(3):1265-1280
The responses of lactating Holstein cows to daily administration of bovine somatotropin (bST) were measured at thermoneutrality (Tn) and under both constant and cycled heat-stress conditions to determine the relationship between thermal status and bST-induced shifts in milk production. All tests included a 5-d acclimation period at Tn (18°C), followed by a 2-d increase in ambient temperature to 28.5°C. After d 3, ambient temperature was cycled between 28.5 (day) and 25.5°C (night) for 4 d. Daily injections with either 31 mg of bST or saline began on d 1 of the experiment. Milk production, feed intake, and respiratory rate (RR) were measured daily. Intraperitoneal, telemetric temperature transmitters were used for a continuous measure of core body temperature (Tcore). Blood samples were collected during each phase to evaluate the changes in serum chemistry in response to bST and heat stress. Following a 15-d recovery, cows were switched across injection treatments and the study was repeated. Milk production decreased by ∼18.4% below the initial yield at Tn by the end of 7 d of heat challenge. Although a reduction in milk production occurred during heat stress in both groups, milk production was higher in bST-treated cows compared with control cows during periods of constant and cyclic heat. Likewise, bST treatment during the entire period increased the milk-to-feed ratio over the control level by ∼11.3%. Plasma insulin-like growth factor 1 and serum nonesterified fatty acids accompanied the increased growth hormone level with bST treatment (∼122.0 and 88.8%, respectively), whereas plasma urea nitrogen was reduced by ∼13.3% to reflect the shift to lipid metabolism. There was no difference in Tcore of the treatment and control groups at Tn. Both bST and control cows increased RR and Tcore above the Tn level by ∼94.8 and 2.9%, respectively, during constant heat, with a greater increase in Tcore of bST-treated compared with control cows (∼0.6%). The increase in RR during heat stress preceded Tcore by 1 d for both groups. During cyclic heat, Tcore decreased by ∼0.4% compared with constant heat in both the control and bST-treated groups. Bovine somatotropin treatment increased milk production similarly during the Tn and heat-stress periods, ∼8.3% over the control; however, the bST-induced increase in milk-to-feed ratio was greatest during the continuous and cyclic heat-stress phases, ∼16.2%. This increase occurred together with the elevation in Tcore. 相似文献
16.
A R Miller E P Stanisiewski R A Erdman L W Douglass G E Dahl 《Journal of dairy science》1999,82(8):1716-1722
Bovine somatotropin (bST) and exposure to long daily photoperiod increase milk yield of dairy cattle. We tested the hypothesis that long daily photoperiod and bST treatment would increase milk yield in an additive manner in lactating cows. At winter solstice, 40 lactating cows were started on a 140-d experiment; cows were greater than 70 d in milk (DIM) and were balanced for uniformity of DIM and milk yield within parity. Cows were randomly assigned to one of four treatments (10/treatment): 1) natural photoperiod, 2) natural photoperiod + bST (14 mg/d Trobest i.m.), 3) long daily photoperiod (18 h of light and 6 h of darkness/d), or 4) long daily photoperiod + bST. Long daily photoperiod increased fat-corrected milk (FCM) yield 1.9 kg/d versus natural photoperiod. Treatment with bST increased FCM 5.7 kg/d versus natural photoperiod, and long daily photoperiod + bST increased FCM 5.8 kg/d versus long daily photoperiod. Long daily photoperiod + bST was additive, increasing FCM 7.7 kg/d versus natural photoperiod. Serum somatotropin increased with bST, but not photoperiod, and bST increased serum insulin-like growth factor-I. Long daily photoperiod tended to increase prolactin; bST had no effect. Long daily photoperiod + bST increased dry matter intake (DMI) relative to natural photoperiod and natural photoperiod + bST; long daily photoperiod increased DMI relative to natural photoperiod + bST. Photoperiod had no effect on net energy balance; however, bST decreased net energy balance. Generally, body weight and milk composition did not differ among treatments. In conclusion, combination of bST with long-daily photoperiod tended to amplify the increases in milk yield observed with either treatment individually. 相似文献
17.
G E Dahl L T Chapin M S Allen W M Moseley H A Tucker 《Journal of dairy science》1991,74(10):3421-3428
Holstein cows received 12 mg/d of growth hormone-releasing factor (continuous i.v. infusion, n = 5), 14 mg/d of bST (single daily i.m. injection, n = 8), or no treatment (controls, n = 8) for 60 d. Compared with controls (31.6 kg/d), bST and growth hormone-releasing factor increased milk yield to 34.2 and 37.0 kg/d, respectively. The increase in milk yield induced by the growth hormone-releasing factor was greater than that for bST. Milk yield was not different among groups following cessation of treatment. Milk energy output was 24.2 Mcal/d in controls, and growth hormone-releasing factor increased milk energy output to 28.5 Mcal/d. Milk energy output of cows receiving bST was 26.1 Mcal/d. Growth hormone-releasing factor increased DMI (23.2 kg/d) over that of controls (21.1 kg/d), whereas bST (21.5 kg/d) did not. Relative to controls, bST increased averaged daily serum somatotropin from 1.3 to 7.6 ng/ml and insulin-like growth factor-I from 67.5 to 116.0 ng/ml. Relative to bST, growth hormone-releasing factor increased serum somatotropin to 16.3 ng/ml and insulin-like growth factor-I to 202.6 ng/ml. Relative to control (115.8 meq/dl) and bST (158.1 meq/dl), growth hormone-releasing factor increased plasma NEFA (230.3 meq/dl). During treatment, calculated energy balance was negative for cows receiving growth hormone-releasing factor but positive for bST and control cows. Milk composition, body condition score, BW, and apparent digestibility of DM were not different among treatments. We conclude that i.v. infusion of 12 mg/d mg of growth hormone-releasing factor has greater galactopoietic activity than i.m. injections of 14 mg/d of bST.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
18.
Postparturient metabolic and production responses in cows previously exposed to long-term treatment with somatotropin. 总被引:1,自引:0,他引:1
I J Lean H F Troutt M L Bruss T B Farver R L Baldwin J C Galland D Kratzer C A Holmberg L D Weaver 《Journal of dairy science》1991,74(10):3429-3445
Postparturient metabolic and production responses were studied for 85 multiparous cows consisting of controls and animals that had been previously exposed to long-term treatment with bST. Older cows previously exposed to bST at high doses (51.6 mg/d) had lower milk yields than controls. However, there were no significant differences compared with controls in milk yield for lower dose (17.2 mg/d) older cows or parity 2 cow groups. The bST-treated groups had higher postpartum DMI, lower serum FFA, lower serum beta-hydroxybutyrate levels, and higher serum glucose than controls. Some bST-exposed groups had lower milk fat but higher milk protein levels. All bST-treated groups had significantly lower ratios of C18 to C4 to 10 milk fatty acids. Control cows of both parity groups were in higher body condition and weighed more than bST-treated cows prior to calving. The differences in postpartum metabolism may be attributed to differences in body composition resulting from bST treatment in the prior lactation, because use of body condition score prior to calving as a covariate did not substantially alter responses. The control cows probably had greater reserves of mobilizable lipid. These contentions are supported by changes in milk composition for bST-treated cows, which were consistent with animals of greater appetite, mobilizing less lipid. The bST-treated cows were probably more energetically efficient milk producers because they produced milk from feed rather than from mobilization of tissue stores. These data suggest that bST use in a prior lactation may have potential benefit in reducing risk of metabolic disorders associated with lipid mobilization in the postparturient period. 相似文献
19.
Overall efficacy of chronically administered recombinant bovine somatotropin to lactating dairy cows 总被引:2,自引:0,他引:2
J H Burton G K MacLeod B W McBride J L Burton K Bateman I McMillan R G Eggert 《Journal of dairy science》1990,73(8):2157-2167
Recombinant bST at daily dosages of 0, 10.3, 20.6, and 41.2 mg/d were injected for 266 d into 8, 10, 9, and 9 Holstein cows, respectively. Treatment effects of recombinant bST were assessed for milk production traits, BW, blood components, and health and reproductive variables. Data reported compare controls to all bST-treated cows. There was an average increase of 18% in 3.5% FCM for bST versus control cows. This increase resulted in enhanced feed efficiency for bST cows, as their DM intakes were not elevated above those of the control cows. Recovery of BW was similar between control and bST groups. Milk composition was unaffected except for a slight decrease in protein percentage during the first 9 wk of treatment, and an elevated SCC between wk 19 and 28. Blood parameters were not different between control and bST cows, except for hematocrit, which decreased with bST treatment. The only health and reproductive parameters affected by bST were mastitis and days open, which were increased in the highest dosage groups. 相似文献
20.
Effect of dietary energy and previous bovine somatotropin on milk yield, mastitis, and reproduction in dairy cows. 总被引:2,自引:0,他引:2
R W Hemken R J Harmon W J Silvia W B Tucker G Heersche R G Eggert 《Journal of dairy science》1991,74(12):4265-4272
Thirty multiparous lactating Holstein cows were blocked according to time of calving and assigned to a 2 x 3 factorial arrangement of treatments in a randomized complete block design to evaluate the effects of two dietary energy concentrations either without or with bST (20.6 mg/d per cow) administered to cows that had not or had received bST during the preceding lactation. Subcutaneous injection of bST began 28 to 35 d postpartum and continued for 39 wk. The dietary energy concentration x bST interaction was not significant for any response variable. Compared with DMI of control cows, DMI was higher for cows receiving bST, being 1.6 and 2.4 kg/d higher for cows receiving bST for one and two lactations, respectively. Milk, fat, and protein yields were higher for cows receiving bST than for controls. Those receiving bST for a second lactation also produced more milk than controls until wk 20; thereafter, milk yields were similar to those of controls. Somatotropin administration had no adverse effect on udder health. Cows receiving bST tended to ovulate less regularly than controls, which may be attributed to their higher milk yield. However, BW gains during lactation were similar for all treatments, indicating that bST-treated cows built energy reserves for the subsequent lactation. Although energy concentrations of the diets had no significant impact on yield, the higher energy diet tended to depress milk fat concentration. Administration of bST to dairy cows for a second, consecutive lactation yielded responses similar for the first 20 wk of the study to those receiving bST for the first time. However, after wk 20, milk yield was less than that by cows receiving bST for the first lactation but similar to that of control cows. 相似文献