The 10th Joint Meeting on Medicinal Chemistry (JMMC 2017) Held in Dubrovnik,Croatia

The Croatian Chemical Society was established in 1926 and has developed over the decades into a society that actively supports all chemical activities in Croatia. The Society has eight divisions, the youngest of which, the Division of Medicinal and Pharmaceutical Chemistry, was established in 2012 and immediately became a member of the European Federation of Medicinal Chemistry (EFMC). The mission of the Medicinal and Pharmaceutical Chemistry Division is the promotion and development of scientific, professional, and educational activities within the medicinal chemistry community in Croatia, as well as to build partnerships and collaborations with other primarily EU‐based medicinal chemistry societies. In Croatia, medicinal chemistry research is ongoing at several institutes, including the University of Zagreb (Faculty of Science, Faculty of Pharmacy and Biochemistry, and Faculty of Chemical Engineering and Technology), national institutes of science (Ru?er Bo?kovi? Institute), and private‐sector drug discovery companies (CRO Fidelta Ltd.). In order to effectively exchange knowledge, ideas, and scientific results, Croatian medicinal chemists meet twice annually.     

关于药物化学教育的思考

药物化学是制药工程、药学以及药物制剂专业的核心课程,是新药研究与开发的龙头学科。文章结合教学改革实践,通过教学方法改革,对有利于提高教学质量的各个环节进行了分析探讨。     

药物化学课程建设的探索与实践

药物化学是制药工程、药物制剂以及药学专业本科教育的专业核心课程.我们以教学内容、教学方法以及教学手段的改进和完善为杠杆,使理论课教学直观、形象、生动,在有限的教学时数内最大限度地充实教学内容,注重实践教学环节,培养学生的实验技能和创新意识.     

The 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry

The second biannual Alpine Winter Conference on Medicinal and Synthetic Chemistry (short: Alpine Winter Conference) took place January 19–23, 2020, in St. Anton in western Austria. There were roughly 180 attendees from around the globe, making this mid-sized conference particularly conducive to networking and exchanging ideas over the course of four and a half days. This report summarizes the key events and presentations given by researchers working in both industry and academia.     

以提高教学质量为主旨 深化药物化学教学改革

药物化学是药学一级学科所涵盖专业——制药工程、药学以及药物制剂专业的核心课程,是新药研究与开发的龙头学科。本文结合教学改革实践,从师资队伍、课堂教学、课程体系以及实践环节等方面,阐述了华东理工大学药物化学课程的建设情况,并就课程建设中尚存的问题和遇到的新困境,提出了解决设想。     

XV All-European Colloquium “Chemical Technology of Polymers” (XV Kunststofftechnisches Colloquium Eurogress)

The XV All-European Colloquium “Chemical Technology of Polymers” was held March 14–16, 1990, in Aachen (Germany). The colloquia are organized by the Institute of Polymer Processing (Aachen) and the German Chemical Society (Frankfurt am Main) and are sponsored by many chemical companies of the areas. Prof. W. Michaeli, director of the Institute of Polymer Processing (Aachen) is the chairman of the organizing committee.     

制药工程专业药物化学理论课教学探索

《药物化学》是制药工程及药物专业一门重要的核心课程,是药学与基础化学的桥梁学科。但目前药物化学教学过程中存在许多问题,针对药物化学教学中出现的问题,文章结合教学改革实践,通过教学方法改革,对各个环节进行了分析探讨,对药物化学教学水平的提高做出了有益的尝试和创新。     

Systems engineering and technology assessment—the NSF-JPS conference

This short note is a somewhat personalized review of the U.S.-Japan Conference on the Application of Process Systems engineering to Chemical Technology Assessment held in Kyoto, Japan, 23–27 June. All of the papers mentioned are available from the author of this communication for a nominal charge. Most of the papers presented at the conference (or slight variations thereof) have been submitted for publication: the first two to “make it” appear in this issue of Computers & Chemical Engineering (E. Rosen and A. C. Pauls; Computer Aided Chemical Process Design: the FLOWTRAN System, and K. Niida, H. Yagi and T. Umeda; An application of Data Based Management Systems to Process Design).     

Sixth Semenov's Readings

Abstract

The Sixth Semenov's? Readings were held on April 15, 1993, in Moscow, at the Institute of Chemical Physics (ICP) of the Russian Academy of Sciences. They were organized by the Scientific Council of Moscow Semenov Institute of Chemical Physics, the Scientific Council of Chernogolovka Institute of Chemical Physics? and by the Scientific Council on Chemical Kinetics and Structure of Compound of the Division of General and Technical Chemistry of the Russian Academy of Sciences. Following annual tradition the Readings were held on the Birthday of Professor Nikolai N. Semenov.     

制药工程专业药物化学实验的教学改革

药物化学是制药工程专业一门重要的专业课程,药物化学实验课旨在加深学生对药化理论知识的理解,培养学生分析问题、解决问题的能力和创新能力。为了更好的达到教学目的,需要加强实验课与专业课的对接,找准实验课的学习重点;加强与其他相关实验课的横向联系;启发他们思考行业内纵向联系;教学时强调实验思路的设计;尝试进行双语教学;最后并选取一种更加具有挑战性的考核方式,以培养合格的学生来满足社会对药学人才的需求。     

The structure and chemical composition of fats and oils

This is essentially a general review of progress during the past ten years both in the chemistry of the glycerides of fats and oils and in the chemistry and nature of their constituent fatty acids. Applications of some of the newer research methods are described and discussed. This paper was presented at the Symposium on the Chemistry & Metabolism of Fats, held at the Rochester meeting of the American Chemical Society. It is published here by special arrangement with the Division of Agricultural & Food Chemistry.     

New electrodes for oxygen evolution in acidic solution

Conventional electrowinning of metals such as zine and copper from 1–1.5 kmol m^–3 H₂SO₄ electrolytes involves anodic oxygen evolution at Pb alloy/PbO₂ anodes operating at 200–800 A m^–2. The oxygen overpotential, estimated to be about 0.6 V, constitutes a significant proportion of the cell voltage (typically 2.5 V for Cu and 3.3 V for Zn). The objective of this work was to lower the anode overpotential and so decrease the process specific energy requirements, by devising new anode materials based on: (1) PTFE-bonded PbO₂ catalysts, supported on Pb–Ag alloys; (2) modification of the pore structure of porous electrodes to maximize the utilization of the available surface without the use of PTFE bonding. Both methods are shown to produce significant benefits in lowering oxygen overpotentials, though the latter technique has been tested only in alkaline electrolytes, as yet. However, with the former approach, substrate oxidation through the porous catalyst layer has been found to cause catalyst shedding after>60 h at 1 kA m^–2, though careful pre-oxidation of the anode substrate appears to extend the anode life.Paper presented at the 2nd International Symposium on Electrolytic Bubbles organized jointly by the Electrochemical Technology Group of the Society of Chemical Industry and the Electrochemistry Group of the Royal Society of Chemistry and held at Imperial College, London, 31st May and 1st June 1988.     

天然药物化学教学改革探讨

天然药物化学是药学专业的一门必修课、核心课程.文章根据天然药物化学课程的特点,探讨采用讨论式教学、理论联系实际、多媒体教学的教学方法提高教学效果;同时适应时代发展,探讨天然药物化学实验教学中贯彻绿色化学理论.     

50 Years European Federation for Medicinal Chemistry (EFMC) – The Ascent of Medicinal Chemistry in Europe

A historical overview of key events that led, 50 years ago, to the foundation of the European Federation for Medicinal Chemistry (EFMC), and the impact this had on promoting and structuring medicinal chemistry as a discipline in Europe. EFMC, together with the growing number of newly established national medicinal chemistry societies or divisions, created the framework for networking and knowledge exchange. This includes organizing conferences, in particular its biennial ‘International Symposium on Medicinal Chemistry (EFMC-ISMC)’. Several interesting trends can be identified from EFMC meetings, EFMC governing bodies, or the federation's recognition of scientific excellence, that highlight changes in the medicinal chemistry community over the last decades, related to affiliation, gender, young scientists, communication tools, and embracing scientific advances.     

Potential drops due to an attached bubble on a gas-evolving electrode

It is shown how the various components of the overpotential due to an attached bubble on an electrode can be separated and estimated. By considering the resistance increments due to the presence on the electrode surface of a bubble, obtained from impedance measurements, it is possible to determine the predominant potential distribution which controls the gas evolution. A relationship between the measured overpotential and the diameter of the bubble is established. The time evolution of the overpotential due to a growing bubble is modelled in the case of the limitation of the bubble growth by dissolved gas diffusion in the solution. In agreement with previous experimental results a linear time variation is found.Paper presented at the 2nd International Symposium on Electrolytic Bubbles organized jointly by the Electrochemical Technology Group of the Society of Chemical Industry and the Electrochemistry Group of the Royal Society of Chemistry and held at Imperial College, London, 31st May and 1st June 1988.     

Summary of discussion on ‘Sciences related to pitch and coke usage in carbon manufacture’

This article is a brief summary of the Discussion session held after the presentation of the preceding papers at the conference organized by the Industrial Carbon and Graphite Group of the Society of Chemical Industry, London, March 1984.     

Main‐chain poly(1,2,3‐triazolium hydroxide)s obtained through AA+BB click polyaddition as anion exchange membranes

A series of aromatic poly(1,2,3‐triazolium iodide)s were synthesized by step growth polymerization of dipropargyl bisphenol A with aliphatic and aromatic diazides followed by quantitative or partial N‐alkylation of the main‐chain 1,2,3‐triazole groups using iodomethane. After characterization by ¹H NMR spectroscopy, SEC and DSC the corresponding self‐standing membranes were obtained by hot pressing. Poly(1,2,3‐triazolium iodide) membranes were converted to the corresponding hydroxide‐containing membranes by anion exchange. Structure–property correlations are discussed based on the evolution of water uptake and ionic conductivity with respect to the ionic exchange capacities of the different materials having distinct chemical structure, quaternization degree and counter‐anion structure. Poly(1,2,3‐triazolium hydroxide) anion exchange membranes exhibit water uptakes below 150% and ionic conductivity in the hydrated state up to 4 mS cm^?1 for ionic exchange capacities up to 3.2 meq g^?1. © 2019 Society of Chemical Industry     

IX All-Union Scientific and Technical Conference on Chemical Admixtures for Polymer Materials

In Tambov from May 22 to May 24, 1990, the regular All-Union Scientific and Technical Conference on Chemical Admixtures for Polymer Materials was held. The conference was organized by the Ministry of Chemical and Petroleum Refinery Industry, the Tambov Regional Board of the All-Union D. I. Mendeleev Chemical Society, the Scientific and Research Institute of Chemicals for Polymer Materials (NIIkhimpolymer, Tambov), and the subsidiary of NIITEKhIM (Cherkassy).     

药物化学教学的探讨

《药物化学》课程具有很强的理论性和实践性,但传统的教学方法往往使课堂变得枯燥乏味,学生失去学习兴趣。文章以药物化学课堂教学为出发点,结合自己的教学实践和经验,从讲述学科前沿知识、充分利用互联网资源、讲述药物发展史、激发学习兴趣、增强学习动力、培养创造性思维、重视药物设计思路的讲述和巧妙设问,激疑促思等七个方面来探讨如何选择合理的教学内容及设计不同的教学方法等。     

浅谈药学实验教学改革

随着药学的飞速发展,社会需要具有创新思想和较强综合能力的复合型药学人才。我们改革传统药学实验教学模式,让学生从查阅文献开始自主确立实验方案,将药物化学、药物分析、药物制剂及药理学实验教学进行交叉、融合,设立开放性实验室,发挥学生主观能动性,让其独立思考、培养创新意识和综合能力,实现客观主义教学观向建构主义教学观的转变。