Urethral advancement and glanuloplasty UAGP vs. MAGPI for distal hypospadias repair

Distal hypospadias is a commonly encountered anomaly. Since its innovation by Duckett the MAGPI procedure has become almost the standard operation for the correction of minor cases. Recently case selection has been advised to avoid possible complications and limitations. Between April 1986 and April 1995, 153 boys were treated for distal hypospadias. In 51 patients (coronal 31, subcoronal 20) a modified technique of urethral advancement and glanuloplasty (UAGP) has been used. The main indications of UAGP were the presence of glanular chordee (7), failed MAGPI (3), circumcised children with distal hypospadias (7), immobile fibrotic urethral meatus (5), and as an alternative to MAGPI (29). The overall complication rate was 4% compared to 3.8% with the MAGPI procedure which has been used in the treatment of 102 patients (glanular 50, coronal 47, and subcoronal 5). We feel this technique can be used effectively in patients with coronal and subcoronal hypospadias, particularly in the presence of distal chordee, fibrotic immobile urethral meatus or MAGPI limitations. Also UAGP could be a useful alternative to MAGPI where tension-free urethral advancement and glanular wrapping can be achieved.     

Long-term outcome evaluation of patients undergoing the meatal advancement and glanuloplasty procedure

A total of 100 consecutive children with distal hypospadias who underwent a variation of the Duckett procedure of meatal advancement and glanuloplasty between 1985 and 1990 was evaluated for outcome in terms of urinary stream, erection, cosmetic appearance and overall parental satisfaction. Minimum interval between procedure and reevaluation for this study was 3 years. Parents of 90 of the 100 children were surveyed by surgeons via telephone and 89 (99%) expressed a high level of satisfaction with the outcome.     

Modified-Mathieu''s technique: a variation of the classic procedure for hypospadias surgical repair

For years, a wide and deep excision of primary cutaneous melanomas has been recommended to achieve a better care and to decrease the risk of local recurrence of the disease. However, recent studies indicate that removal of peritumoral tissue beyond complete excision of the primary neoplasm does not decrease significantly the risk of local metastases. In addition, it confers no benefit to the patient survival.     

PLGA材料仿生改性的最新进展

聚乳酸-乙交酯（PLGA）因具有优良的可降解性而在医用生物材料中得到了广泛应用，然而由于其表面缺乏细胞识别位点，以及存在亲水性和细胞亲和性不足等缺点，影响了细胞在其表面的粘附生长。为了得到生物功能和亲水性均较理想的聚乳酸类生物降解高分子，通过物理或者化学的方法在材料中引入胶原或多肽对其进行改性，赋予材料生物信号，以提高其生物功能，使其在组织工程支架的研究和临床应用更加广泛。该文主要对PLGA仿生改性的最新进展进行综述。     

Hand-foot-uterus-(HFU) syndrome with hypospadias: the hand-foot-genital- (HFG) syndrome

Three brothers with the typical findings of the HFU-syndrome, but in addition with various degrees of hypospadias are reported. The family history otherwise was negative. The similarity of the "pattern-profile" of these cases with the mean pattern of the 11 previously reported ones is striking, as expressed by a product moment correlation of 0.83, 0.8 and 0.78 respectively. The widening of the concept of the HFU to that of a HFG-syndrome, as suggested by Poznanski et al, in 1974, is discussed.     

Appendiceal cecoplication: a modification of the Malone antegrade colonic enema procedure

Laryngopharynx and tracheobronchial tree were examined in 20 patients with purulent mediastinitis (PM) of different origin. Endoscopically, upper posterior mediastinitis was characterized by swallowing of membraneous wall into the lumen due to pressure outside. The authors recommend diagnostic application of laryngobronchofibroscopy to verify PM following traumas of the respiratory tracts and therapeutic use of the above procedure to treat PM complications; propose to perform nasotracheal intubation using bronchofibroscope as a method of choice in prevention of asphyxia in PM patients provoked by laryngeal edema.     

A modification of the bladder flap of Boari for the management of defects of the distal ureter (author's transl)

The results of the management of defects of the distal ureter of various causes with a bladder flap of Boari including the anti-reflux implantation of the ureter in 65 patients are reported. 50 patients had prior gynaecological operations. The other 15 patients had prior urological operation, inflammations (tuberculosis), tumors or anomalies of the ureter. The follow-up time ranges from a few weeks to five years and 80-90% of the patients were cured. 24 of these patients had prior malignant tumors.     

Stress osteotomy of the distal radius- and ulna metaphysis (Illarramendi procedure): an alternative treatment method in lunate necrosis

Using conventional in vitro extracellular field potential recordings we have investigated both short- and long-term synaptic plasticity in the hippocampal CA1 area of mice infected with ME7 scrapie. In agreement with earlier studies, no changes were seen in the properties of the Sch?ffer collateralevoked field excitatory postsynaptic potential during the early stages of the disease (up to 160 days, post inoculation, d.p.i) after which time the recorded potentials were seen to attenuate. Also, up to this time no changes were seen in either paired-pulse facilitation or post-tetanic potentiation, which are short-term phenomena associated with brief elevations in presynaptic calcium levels. However, there was a significant shift from the ability of slices to maintain long-term potentiation (LTP) from 100 d.p.i. onwards. In all of these experiments short-term potentiation (STP) was preserved, suggesting that from the time that abnormal PrP becomes detectable, or perhaps even earlier, the mechanisms responsible for stabilizing the maintenance phase of LTP are impaired. This result is discussed in terms of the relationship between STP and LTP and how this might be compromised by the conversion of cellular prion protein (PrPC) to the scrapie, protease resistant form of PrP (PrPSc).     

An experimental procedure for the modification of psychotic behavior.

Subjected a 47-yr-old hospitalized female exhibiting hallucinatory behavior to a self-monitoring procedure with and without social reinforcement. After 16 days of treatment, hallucinations were extinguished with no remissions reported for approximately 6 mo. Other aspects of her behavior also showed improvement. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The reduction of anxiety vulnerability through the modification of attentional bias: A real-world study using a home-based cognitive bias modification procedure.

Recent laboratory work suggests that biased attentional responding to negative information causally impacts anxiety reactivity to a contrived laboratory stressor. However, it remains unknown whether such attentional bias contributes to real-world anxiety vulnerability. In the present study, the authors addressed this issue by experimentally inducing biased attentional response to emotionally negative stimuli, using a home-based attentional training program and then examining the influence of this attentional manipulation on trait anxiety scores and on state anxiety responses to a subsequent stressful life event. The attentional bias modification procedure was effective in inducing attentional avoidance of negative information. Furthermore, this attentional manipulation served to reduce trait anxiety scores and to attenuate state anxiety responses to the subsequent naturalistic stressor. These findings support the hypotheses that biased attentional responding to emotionally negative information contributes causally to real-world anxiety vulnerability. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Salvage procedure for failed Bowers' hemiresection interposition technique in the distal radioulnar joint

Three patients who continued to have distal radioulnar joint pain following Bowers' hemiresection interposition technique were treated by converting the resection arthroplasty into a Sauvé-Kapandji procedure. The resected 10 mm segment from the distal ulnar metaphysis was used as an interposition bone graft in the arthrodesis site, placed between the sigmoid notch of the radius and distal end of the ulna. After a minimum follow-up of 3 years, all three patients were satisfied with the procedure, were pain-free, and the preoperative range of wrist and forearm motion had increased. All three returned to their previous working activities.     

Urethral sphincterotomy for delivery of vesical calculus in the mare: a case report

A case of vesical calculus in which haematuria was not a presenting sign is described. Methods of removal of vesical calculi are discussed. In this case, urethral sphincterotomy facilitated delivery.     

A new procedure for keratometry (author's transl)

The principle of construction of a keratometer is explained which shows digitally the radii of curvature of the cornea obtained by automatic optical measurement and processed by an inbuilt computer.     

Alternative surgical method in malalignment of healed distal radius fracture: Kapandji-Sauvé procedure

OBJECTIVE: To evaluate the neurovascular structures at risk with the placement of anterior-posterior locking screws in the proximal femur. DESIGN: Cadaveric study. MAIN OUTCOME MEASURE: Anatomic relationships. RESULTS: The femoral artery lies medial to the femur, and its branches cross the anterior femur more than four centimeters distal to the lesser trochanter. Branches of the femoral nerve cross the anterior femur proximal to the lesser trochanter and start four centimeters distal to the piriformis fossa. CONCLUSIONS: Risks to the neurovascular structures during anterior-posterior locking in the proximal femur are diminished if locking is performed above the level of the lesser trochanter.     

Design and biomechanics of a plate for the distal radius

A dorsal plate for the distal radius was designed to provide rigid fixation and thus allow early motion. It functions as a blade plate, lessening the role of metaphyseal screws, and providing internal neutralization rather than compression. The rigidity and strength of the plate were compared to the existing T-plate in an unstable, extra-articular fracture model in paired, fresh-cadaver, axially loaded radii. The dorsal plate construct was significantly stronger and more rigid than the T-plate construct. The failure mode was similar for both plate types; 8 of 10 constructs failed with plate bending and screw loosening, while the oldest specimen pair showed primary bone failure. Compared to the T-plate, the dorsal plate transmitted a greater single axial load from the articular surface to the shaft.